The Future of Prostate Cancer Care

The Future of Prostate Cancer Care

Today, we’ll be tackling the future of prostate cancer care. We’ll be reflecting on what prostate cancer care means in practice, how the way we think about the disease is shifting, and must continue to shift in the years ahead. Scientific advances have transformed treatment in recent years, yet the lived reality of prostate cancer still extends far beyond the clinic. The disease reshapes daily life, and may leave men and their families grappling with difficult choices about how best to manage it. Dr. Güneş Taylor is joined by three key voices at the centre of this story, following the prostate cancer journey from diagnosis through to long-term management, and asking how patients and clinicians can work together to re-think what patient-centred care could mean in the years to come. This episode is brought to you in collaboration with Bayer, part of their Prostate Cancer Perspectives series. PP-UN-ONC-GB-0168. November 2025 References Bray F, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024;74(3):229-263 (Prostate cancer is the second most common cancer in men and the fifth leading cause of cancer death worldwide) James D, et al. The Lancet Commission on prostate cancer: planning for the surge in cases. Lancet. 2024;403(10437):1683–1722 (Each year, around 1.5 million men are diagnosed and nearly 400,000 lose their lives to the disease.1 And the numbers are rising. Diagnoses are projected to double from 1.4 million annually in 2020 to 2.9 million by 2040) Siegel RL, et al. Cancer statistics, 2022. Ca Cancer J Clin. 2022;72:7–33 (In the U.S., the proportion of men diagnosed with advanced-stage prostate cancer has doubled in recent years, due to increasing incidence of advanced-stage disease and changing guidelines regarding the prostate specific antigen screening test, implemented in the U.S. in 2012) Dodkins J, et al. Geographic, socioeconomic and demographic inequalities in the incidence of metastatic prostate cancer at time of diagnosis in England: a population based evaluation. BMJ Oncology. 2025;4:e000643 (In England, nearly one in five men only receive a diagnosis once their cancer has spread) Calvo-Schimmel A, et al. Supportive care interventions and quality of life in advanced disease prostate cancer survivors: An integrative review of the literature. Can Oncol Nurs J. 2021;31(4):412-429 (Advanced prostate cancer is often associated with long-term challenges leading to greater levels of unmet needs in supportive care) Learn more about your ad choices. Visit podcastchoices.com/adchoices

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An Anatomy Of Truth: Conversations on Truth-Telling

An Anatomy Of Truth: Conversations on Truth-Telling

Not everyone tells the truth. ‘Read my lips: no new taxes.’ ‘This isn’t going to hurt.’ ‘I see no ships, my lord.’ ‘Of course I love you.’ When can we know what to believe? Four out of five of us don’t think politicians tell the truth, according to a recent MORI poll. But is telling the truth always the right or best thing to do? If it isn’t, what happens to trust? If it is, are there different kinds of truth? Do we always want to hear the truth? Do different professions need to have systemically different attitudes to truth-telling? Is there a moral difference between outright lies, falsehoods, deceits, dissimulation and just plain old ‘economy with the actualité’? In October 1013, Intelligence Squared headed to London's Westminster Abbey to discuss truth with a politician (Jack Straw), a journalist (Max Hastings), a scientist (Professor Robert Winston) and a poet (Wendy Cope). — We’d love to hear your feedback and what you think we should talk about next, who we should have on and what our future debates should be.  Send us an email or voice note with your thoughts to podcasts@intelligencesquared.com or Tweet us @intelligence2.  And if you’d like to support our mission to foster honest debate and compelling conversations, as well as ad-free podcasts, exclusive bonus content, early access and much more, become a supporter of Intelligence Squared.. Just visit intelligencesquared.com/membership to find out more.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

27 Loka 20161h 3min

Pornography is Good For Us: Without it We Would Be a Far More Repressed Society

Pornography is Good For Us: Without it We Would Be a Far More Repressed Society

Hooray for porn! What would we be without it? Bored, repressed, frustrated. Porn allows the timid to indulge fantasies they’d never live out in real life and the adventurous to experiment with new forms of pleasure. Now that it has stepped down from the top shelf and waltzed across the internet we can all enjoy it. All we need to do is stop pretending it’s something dirty and come straight out and salute it. Or maybe not. Porn after all is selling a lie: that women are always eager to engage in extreme practices, that bodies are always tanned and buffed, orgasms explosive. Isn’t this a recipe for frustration and disappointment? And to attract the restless voyeur, porn is always having to up the ante – cyber-sex is getting ever more degrading and extreme. Men are finding it harder to be satisfied with their real world partners, women are feeling inadequate and pressured to live up to the cyber-competition – this is the reality of pornland. So which is it – the great liberator of the libido or a blight on... — We’d love to hear your feedback and what you think we should talk about next, who we should have on and what our future debates should be.  Send us an email or voice note with your thoughts to podcasts@intelligencesquared.com or Tweet us @intelligence2.  And if you’d like to support our mission to foster honest debate and compelling conversations, as well as ad-free podcasts, exclusive bonus content, early access and much more, become a supporter of Intelligence Squared.. Just visit intelligencesquared.com/membership to find out more. Learn more about your ad choices. Visit podcastchoices.com/adchoices

20 Loka 20161h 2min

PJ O'Rourke on the US Presidential Clash

PJ O'Rourke on the US Presidential Clash

As Donald Trump faces Hillary Clinton in what has been one of the most vitriolic and unpredictable races in recent US election history, we were joined by America’s leading political satirist PJ O’Rourke, just a month ahead of US election day, as he cast his merciless eye over both candidates. He is known for taking no prisoners on either side of the political divide. He has already called Trump ‘a flying monkey’ and Clinton ‘Jimmy Carter in a pantsuit’. As author of such bestsellers as 'Don’t Vote: It Only Encourages the Bastards', and with more citations in 'The Penguin Dictionary of Humorous Quotations' than any other living writer, O’Rourke has been lambasting American politics for some 40 years. Such is his stature that even President Nixon conceded: ‘Whether you agree with him or not, PJ writes a helluva piece.’ O’Rourke will delved into why, in his own words, ‘America is experiencing the most severe outbreak of mass psychosis since the Salem witch trials of 1692’. As a sign of how the race for the... Support this show http://supporter.acast.com/intelligencesquared. See acast.com/privacy for privacy and opt-out information. Learn more about your ad choices. Visit podcastchoices.com/adchoices

14 Loka 20161h 3min

The Gene: Unlocking the Human Code, with Siddhartha Mukherjee

The Gene: Unlocking the Human Code, with Siddhartha Mukherjee

Genetics has revolutionised not just how we think of biology but how we think of ourselves. We are, in the words of one geneticist, the first organism that has ‘learned to read its own instructions’. Now, with the breakthrough of gene-editing technology — whose precision allows us to alter a single letter of DNA — we can now not only decipher but rewrite our genetic code. We may soon be able to treat diseases such as cancer not simply with drugs, but with genetic manipulation. Yet behind this medical revolution lies the prospect of something altogether more worrying. Already, we possess the technology to add to our genetic code at will, and thus create the world’s first generation of ‘transgenic’ humans. As we intervene genetically on ourselves with ever more accuracy, do we risk changing what it means to be human? In a potential quest for the genetically ‘normal’, will we risk annihilating the very diversity and mutations on which evolution depends? These are some of the questions that the Pulitzer... Support this show http://supporter.acast.com/intelligencesquared. See acast.com/privacy for privacy and opt-out information. Learn more about your ad choices. Visit podcastchoices.com/adchoices

7 Loka 20161h 3min

Karl Marx Was Right

Karl Marx Was Right

We can’t say Karl Marx didn’t warn us: capitalism contains the seeds of its own destruction. In their chase for ever higher profits, the capitalists shed workers for machines. The higher return on capital means that the share of profits rises and the share of wages falls, and soon the mass of the population isn’t earning enough to buy the goods capitalism produces. And that’s exactly what’s been happening over the past four years of the Great Recession: ever increasing income inequality, leading to ever weaker aggregate demand – temporarily disguised by an unsustainable credit binge – leading to collapse. You don’t have to be a communist to see that this is so. We should all be Marxists now. Or should we? Every time capitalism hits an inevitable bad patch, Marx’s name is invoked with wearisome regularity. But no serious economist or political thinker – with the possible exception of Gordon Brown – has ever suggested capitalism can break free of booms and busts. Once bust, as we’ve seen time and again, the... Support this show http://supporter.acast.com/intelligencesquared. See acast.com/privacy for privacy and opt-out information. Learn more about your ad choices. Visit podcastchoices.com/adchoices

30 Syys 20161h 2min

The End of Antibiotics?

The End of Antibiotics?

This panel discussion took place at the New York Academy of Sciences in September 2016 and was produced by Intelligence Squared, in partnership with the World Health Organisation and the Wellcome Trust. There’s a time bomb ticking that is going to affect us all. Whether you are a sub-Saharan subsistence farmer or a New Yorker buying a super-smoothie in Wholefoods, there will be no escape. The threat? An invisible army of super-resistant bacteria is on the march. Antibiotics, the drugs that have saved millions of lives and are critical for the world’s health and wellbeing, have become a victim of their own success. Their overuse and misuse have helped bacteria and other infectious bugs to develop resistance to them, meaning that many infections are no longer effectively treatable by current medicines. Every year 700,000 people die of drug-resistant infections, and experts predict that this number could rise to 10 million. On top of this, recent research points to a possible link between antibiotics and... Support this show http://supporter.acast.com/intelligencesquared. See acast.com/privacy for privacy and opt-out information. Learn more about your ad choices. Visit podcastchoices.com/adchoices

23 Syys 20161h 11min

Yuval Noah Harari on the Myths we Need to Survive

Yuval Noah Harari on the Myths we Need to Survive

Myths. We tend to think they’re a thing of the past, fabrications that early humans needed to believe in because their understanding of the world was so meagre. But what if modern civilisation were itself based on a set of myths? This is the big question posed by Professor Yuval Noah Harari, author of 'Sapiens: A Brief History of Humankind', which has become one of the most talked about bestsellers of recent years. In this exclusive appearance for Intelligence Squared, Harari argued that all political orders are based on useful fictions which have allowed groups of humans, from ancient Mesopotamia through to the Roman empire and modern capitalist societies, to cooperate in numbers far beyond the scope of any other species. Support this show http://supporter.acast.com/intelligencesquared. See acast.com/privacy for privacy and opt-out information. Learn more about your ad choices. Visit podcastchoices.com/adchoices

19 Syys 20161h 4min

David Eagleman on the Science of De- (and Re-) Humanisation (and Why it Matters)

David Eagleman on the Science of De- (and Re-) Humanisation (and Why it Matters)

Which side were you on? The Jets or the Sharks? The Capulets or the Montagues? The Greeks or the Trojans? Antony or Caesar? William or Harold? And so the list goes on ... Indeed, maybe the whole of human history is the story of group-making and group-breaking. The passions of loyalty and love for the in-group are matched by the de-humanising indignation and hatred for the out-group. But what's actually going on in the chemical soup of the brain when Agamemnon gathers his heros-to-be and sets sail after Helen? Will peering into that soup - as neuroscientist David Eagleman is now doing - actually give peace a chance? Maybe utopia can come out of the lab. Will a scientific understanding of love and hate deliver social programmes that undermine the nastiness without sacrificing the good? — We’d love to hear your feedback and what you think we should talk about next, who we should have on and what our future debates should be.  Send us an email or voice note with your thoughts to podcasts@intelligencesquared.com or Tweet us @intelligence2.  And if you’d like to support our mission to foster honest debate and compelling conversations, as well as ad-free podcasts, exclusive bonus content, early access and much more, become a supporter of Intelligence Squared.. Just visit intelligencesquared.com/membership to find out more.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

16 Syys 20161h 3min

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