#18 Lessons from the ADRENAL trial
EvolutionMedicine29 Tammi 2018

#18 Lessons from the ADRENAL trial

This week Joe Alcock and Coffee Brown get into the weeds of the ADRENAL trial - a huge study designed to answer the question - does giving steroids to patients with sepsis help or hurt? I say it hurts, Coffee is not so sure. We talk about why anti-inflammatory treatments have always failed in patients with septic shock. The lesson, it turns out, is an evolutionary one.

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Jaksot(46)

#14 Epigenetics with Coffee

#14 Epigenetics with Coffee

Coffee Brown and Joe Alcock return to talk about epigenetics. Does it pose a challenge to Darwinian evolution? Does epigenetics vindicate Lamarkism, the inheritance of aquired characteristics? We mix ...

18 Loka 201757min

Too Sweet Or Just Right

Too Sweet Or Just Right

In this 13th episode of the EvolutionMedicine 'cast Joe Alcock discusses the recent New England Journal of Medicine article about intensive insulin treatment for hyperglycemia (high blood sugar) in cr...

25 Touko 201723min

#12 A Vitamin For Sepsis

#12 A Vitamin For Sepsis

Can a little vitamin C given IV help cure sepsis. Recently this idea got a lot of press, and a trial of hydrocortisone and vitamin C was published in the journal Chest. Does this make any sense? What ...

2 Touko 201716min

#11 High anxiety with Coffee Brown - a discussion about stress

#11 High anxiety with Coffee Brown - a discussion about stress

Coffee Brown MD joins Joe Alcock to discuss whether stress is good or bad for us. We also discuss the election and the idea that stress hormones play a role in political choices.

14 Marras 20161h 28min

#10 Evolution Of Dietary Inflammation With Melissa Franklin

#10 Evolution Of Dietary Inflammation With Melissa Franklin

Joe Alcock and Melissa Franklin PhD explain why some diets cause inflammation and others don't. The answer, as usual, involves the microbiome, and in our evolutionary biology. We also discuss how the ...

5 Loka 201644min

#9 Extreme Environment Encephalopathy and Zombies

#9 Extreme Environment Encephalopathy and Zombies

Joe Alcock is joined by guest Darryl Macias who describes his recent expedition to Shishapangma to help with a body recovery at high altitude. We also discuss the brain at its limits in extreme enviro...

23 Syys 201651min

#8 Altitude Adaptation And Maladaptation

#8 Altitude Adaptation And Maladaptation

Native people of the Andes can cope with high altitude better than the rest of us genetic lowlanders. How is this so? We cover the evolutionary biology of high altitude peoples of the Andes, Himalayas...

2 Syys 201627min

# 7 Teaching Evolutionary Medicine

# 7 Teaching Evolutionary Medicine

How evolution can teach students healthy skepticism in medicine. Will robots replace doctors?

2 Syys 201624min

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