Part 35 - Dr. Thomas Seyfried on Cancer as a Metabolic Disease, More Effective Therapies, and Treating it Without Toxicity

Part 35 - Dr. Thomas Seyfried on Cancer as a Metabolic Disease, More Effective Therapies, and Treating it Without Toxicity

Dr. Thomas Seyfried is a Professor of Biology at Boston College, and received his Ph.D. in Genetics and Biochemistry from the University of Illinois. He then worked as an assistant professor in the neurology department at the Yale school of medicine. He has over 180 peer-reviewed publications and is author of the book, Cancer as a Metabolic Disease. He recently received a Lifetime Achievement Award from the Academy of Complimentary and Integrative Medicine.

I got a chance to meet and interview him at the Metabolic Health Summit earlier this year. You'll notice we did this podcast shortly after the Super Bowl. In case people aren't familiar with American football the New England Patriots had just beaten the LA Rams.

I hope people look up the paper he recently published that we mention and watch his presentation I linked to in the show notes and go deeper on this topic. It's very surprising to learn of this completely new view on cancer if you haven't heard of it before. This really shouldn't be very surprising to anyone, however, because of course our modern diet and lifestyle would have the biggest effect on the rising cancer rates. And of course fixing these things would also be a major part of the treatment. He's really doing legendary work. So without further ado, here's professor Seyfried.

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http://indiegogo.com/projects/food-lies-post

Support me on Patreon! http://patreon.com/peakhuman

Show Notes

  • Dr. Thomas Seyfried believes cancer is a metabolic disease, not a genetic disease and explains in simple terms why that is
  • The mitochondria in your cells make energy (ATP)
  • There's 2 types of energy: ancient energy which is a fermentation metabolism which means you can make energy without oxygen, or respiration where you make energy from breathing air
  • Cancer cells ferment - therefore they don't use oxygen
  • Not all cancer cells have genetic mutations, but all cancer cells ferment
  • The mitochondrial metabolic theory says that the organelle that makes energy from respiration is defective, forcing the cell to ferment. When the cell ferments, mutations collect in the nucleus
  • This means the genetic mutations seen in cancer cells come from a downstream effect of disruption of energy metabolism
  • The cancer cell has to consume a large amount of glucose and the amino acid glutamine in order to survive on a fermentation metabolism
  • On the other hand, normal cells use oxygen and very little amounts of glucose
  • This should make sense to a lot of people because they've probably heard cancer cells need a lot of glucose and if you starve them of that they die
  • Have to re-emphasize the fact that the DNA damage comes as a downstream effect
  • Damaged mitochondria, instead of making ATP, make Reactive Oxygen Species (ROS) or oxidative stress (which causes a lot of problems in our body)
  • The oxidative stress also causes damage to the nucleus and the genome
  • The field of cancer research studies effects instead of causes
  • We're not treating cancer by looking at the root cause - it's absurd - how would we ever cure it?
  • This is supported by thousands of experiments and studies
  • Obvious step to treat cancer is to deprive the cancer cells of glucose and glutamine and transition healthy cells into the use of ketones which they can readily use
  • We evolved as a starving creature and convert fatty acids into ketones and usable forms of energy
  • Cancer cells can't use ketones
  • There's no dietary way to restrict glutamine to the cancer cells so drugs have to be used
  • Basically nobody he's heard of is treating it this way
  • If it's so clear this is how cancer works, why has this not reached the mainstream?
  • The Federal government puts out websites saying cancer is genetic, medical schools teach it's genetic, leading cancer clinics tell patients it's genetic
  • Entrenched beliefs continue this. Also funding money is all based around the genetic theory
  • If you look at the mitochondria of any cancer cell under an electron microscope you can easily see the damage to the organelles and mitochondria
  • Cancer is a result of the industrialization as a society
  • Cancer is so rare throughout history or with non-industrialized societies they don't even have the word for it in their language
  • Cancer comes from all kinds of things like pollution, chemicals, radiation, hypoxia, infections, chronic inflammation, even some rare inherited diseases like BRCA1 (but it has to damage the mitochondria)
  • These are all secondary - the root cause is damage to the respiration
  • Obese people have higher rates of cancer and also higher inflammation (measured by C reactive protein)
  • To avoid cancer it's as simple as avoiding diets and lifestyles that risk damage to the mitochondria
  • Metabolic therapies need to at least be options for people
  • Problem is doctors aren't aware of them or aren't trained on them
  • Therapeutic ketosis is a medicine - it's different than just a diet (which is a turn-off to a lot of medical professionals)
  • There's therapeutic weight loss and toxic weight loss
  • Using a suite of therapies to cure cancer including ketogenic metabolic therapy and hyperbaric oxygen therapy
  • Hyperbaric oxygen creates reactive oxygen species that kills cancer cells but healthy cells using ketones are protected from oxidative stress and are fine
  • Burning ketones creates less ROS (which is a good thing) and is why many people without cancer eat a ketogenic diet
  • ROS damages tissues and is why you age
  • He published the glucose-ketone index calculator
  • People need to realize sweets are a treat once in awhile - not an everyday thing
  • The food industry has played into our ancient desires for sweet
  • Otto Warburg studied cancer in the early 1900s
  • He found that cancer cells would grow in an 100% oxygen environment - they continue to ferment and create lactic acid
  • Because their mitochondria are defective they can't switch back to oxidative phosphorylation
  • He recently published a paper filling in the gaps from Otto Warburg's work
  • Missing link was the glutamine that cancer cells can also use
  • Have to pulse the glutamine so the immune system can do it's job and clear out the dead cells
  • He's developed the press-pulse system in his lab to attack tumors strategically
  • Almost there with dosage, timing, and schedule - when done with this will have the pathway to resolution
  • He's having trouble getting funding for this for some reason
  • One problem is people have created separate little communities and foundations around their specific type of cancer even though they all have the common metabolic foundational problem
  • People are going to have to participate in the management of their disease and the culture of the diseases has to change
  • Another problem is the high cost of these standard therapies - people have to pay $400k
  • His paper looking at research conducted on cancer https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941741/
  • If you take a normal cytoplasm and implant a nucleus with a tumor you get normal cells. But if you implant a normal nucleus to a cell with damaged cytoplasm, you get more tumor cells. This shows it's the damaged mitochondria in the cytoplasm, not the DNA in the nucleus
  • The wheelchair doesn't cause your legs to not work
  • Needle biopsies are putting people at risk and are pointless
  • He calls this general misunderstanding of cancer the biggest tragedy in the history of medicine
  • What do critics of his views say? They try to create doubt
  • They rely on private funding and some great organizations supporting this research
  • Travis Christofferson's foundation https://foundationformetaboliccancertherapies.com
  • His book Tripping Over the Truth https://www.amazon.com/Tripping-over-Truth-Overturning-Entrenched/dp/1603587292/
  • Dr. George Yu's foundation https://yufoundation.org
  • Presentation by Dr. Seyfried https://www.youtube.com/watch?v=APwnkpD_BfI&frags=pl%2Cwn
  • Dr. Seyfried's book https://www.amazon.com/Cancer-Metabolic-Disease-Management-Prevention/dp/0470584920/

Preorder the film here: http://indiegogo.com/projects/food-lies-post

Support me on Patreon! http://patreon.com/peakhuman

Film site: http://FoodLies.org

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Part 2 - Dr. Ted Naiman on Lifelong Health

Part 2 - Dr. Ted Naiman on Lifelong Health

Our first guest is the great Dr. Ted Naiman. Maybe you know who that is, maybe you don't…. But I'll just say, listen to the man. Some of this may be new to people who aren't total nutrition nerds - but just know it's the truth. Dr. Naiman might be the most on-point authority on how your metabolism works, how to stay lean and fit, and how to eat optimally. He has a ton of experience with thousands of patients and sees first hand how different diets affect all different kinds of people. I've learned so much from him and a lot of things clicked into place once I started really understanding his way of thinking about nutrition. So before we start, just remember that we're trying to break even on all this by crowdfunding to get the film made. Please pre-order it now on Indiegogo - just search for Food Lies or click here - Thank you! http://indiegogo.com/projects/food-lies-post Show Notes How insulin resistance develops Can't eat both high carb and high fat How a few of his patients are "pulling off" veganism with a lot of supplementation and restrictions Problems with vegan and low protein diets Your body is a battery - it runs on stored body fat. How this works. Protein sparing modified fast WHy juice cleanses and starvation is absurd and doing more harm Lean mass and fat mass Macronutrient wars and how America got obese Too much protein and gluconeogenesis is overblown Low carb and low fat both have success stories - what's the unifying theory? The amazingly simple (and free) way Ted stays ripped Preorder the film here: http://indiegogo.com/projects/food-lies-post Podcast site: http://Peak-Human.com Film site: http://FoodLies.org Youtube: http://youtube.com/c/foodlies Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

21 Kesä 201850min

Part 1 - The Unifying Theory of Nutrition

Part 1 - The Unifying Theory of Nutrition

This episode gives you a complete look at nutrition. Learn what to eat, what not to eat, and why. Learn how basically all chronic diseases come from us moving away from the foods our ancestors ate (you know, the ones free of all chronic diseases). Everything will make a lot more sense after this episode. Preorder the film here: http://indiegogo.com/projects/food-lies-post Show Notes Pat and Marife - who they are and why we are doing this Why I'm doing this film Major health myths cholesterol Saturated fat Link to studies about sat fat Vegetable oils are harmful https://chriskresser.com/how-too-much-omega-6-and-not-enough-omega-3-is-making-us-sick/ What causes clogged arteries WHO and other orgs have vegetarian members which should be a conflict of interest Meat and cancer https://chriskresser.com/the-truth-about-red-meat/ Processed meat Nitrates and nitrites https://chriskresser.com/the-nitrate-and-nitrite-myth-another-reason-not-to-fear-bacon/ Salt is not bad for us https://www.scientificamerican.com/article/its-time-to-end-the-war-on-salt/ Healthcare company reversing type 2 diabetes with low carb, high fat diets http://virtahealth.com Published study of this https://link.springer.com/article/10.1007%2Fs13300-018-0373-9 What you get from animal products that you can't get from plants Study of iron absorption of spinach "Even though some plants, such as spinach, are high in iron, the body can only absorb 1.4-7% of the iron in plants whereas it can absorb 20% of the iron in red meat" https://www.ncbi.nlm.nih.gov/pubmed/1745900 Influence of dietary carbohydrate and fat on LDL and HDL particle distributions. https://www.ncbi.nlm.nih.gov/pubmed/16256003 No link between saturated fat and CVD https://www.ncbi.nlm.nih.gov/pubmed/20071648 https://news.osu.edu/news/2014/11/21/study-doubling-saturated-fat-in-the-diet-does-not-increase-saturated-fat-in-blood/ A total of 6,786 people have participated in these 76 studies. 6 have lasted 2 years or more to prove the low carb diet is effective https://docs.google.com/spreadsheets/d/1Ucfpvs2CmKFnae9a8zTZS0Zt1g2tdYSIQBFcohfa1w0/edit Weston A. Price info https://www.westonaprice.org The great book The Vegetarian Myth http://www.lierrekeith.com Preorder the film here: http://indiegogo.com/projects/food-lies-post Film site: http://FoodLies.org Podcast site: http://peak-human.com Youtube: http://youtube.com/c/foodlies Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

19 Kesä 201858min

Peak Human Podcast Preview

Peak Human Podcast Preview

Hi Everyone, I'm Brian Sanders, and I'm making a feature length documentary called Food Lies which is about the sordid history of our dietary guidelines, the epidemic of chronic disease and obesity that followed, what the new science is telling us humans should actually be eating, and how to eat that food sustainably. As I make the film, I'm talking to a bunch of experts who have graciously lent me their time to create this podcast. Actually, you can think of this as a free audio course on nutrition - all without ads. I'm doing this to support the Food Lies film which is now crowdfunding on Indiegogo.com. Over the next 13 episodes you'll hear from some of the top experts in their field, specifically chosen to cover all areas of this complicated subject. There's so much conflicting health information out there, it's almost impossible to know who and what to believe. I quit my job and have spent the past year researching it from all sides, even veganism, and this audio series provides an overview. By the end, all the confusion around health and what we should eat should make sense. You'll learn so much more of the science behind this all, like the real deal with cholesterol and saturated fat, how to prevent cancer and diseases, if carbohydrates can be part of a healthy diet, and how ruminants like cows are essential for the health and future of the soil and environment The first part of the season includes these amazing doctors, researchers, and journalists: Professor Tim Noakes Dr. Ted Naiman Dr. Zoe Harcombe Gary Taubes Dr. Dom D'Agostino Denise Minger Dr. Shawn Baker Amy Berger Peter Ballerstedt And more to come There's so much awesome information in this audio series, I can't wait to share it with everyone. So please subscribe now wherever you get your podcasts. You're probably wondering "So who's this Brian guy?" by now. Well, first of all, I've been a filmmaker since middle school. I've also built and sold a tech company, worked as a mechanical engineer, and now, I've quit my job to devote the rest of my life to this cause. I've read dozens of books, watched dozens of films, watched hundreds of lectures and presentations, and listened to over a thousand hours of podcast episodes on this subject. I've looked at all the different approaches and figured out what the common truths are and what's BS. I now understand the unifying theory of nutrition that pulls together all sides - from Paleo to Vegan. Nobody is really talking about this - everyone is too busy being blinded by their tribe. I've also put this research into practice, and now, at age 35, I'm in the best shape of my life. My vitals and blood work are flawless and I haven't been sick in 3 years. The same goes for countless family and friends, as well as millions around the world. I'm so excited to share this all with you. Once again, the film is called Food Lies and we're crowdfunding now on Indiegogo.com. Please support us and preorder a copy the film. We also have tons of great rewards like the limited edition Real Foods challenge coin. Also don't forget to subscribe to this podcast as the episodes will be airing soon. You can find out more at peak-human.com and foodlies.org and find us on Twitter (@FoodLiesOrg) and Instagram (@food.lies). Thanks again! Preorder the film here: http://indiegogo.com/projects/food-lies-post Podcast site - http://Peak-Human.com Film site - http://FoodLies.org Youtube: http://youtube.com/c/foodlies Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

1 Kesä 20186min

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