Biohacking News Weekly Update : 1363

Biohacking News Weekly Update : 1363

This episode covers:


• Cocoa Extract Cuts Heart Deaths

A massive COSMOS trial found that older adults taking high flavanol cocoa extract daily saw a 27 percent reduction in cardiovascular deaths along with drops in inflammation markers like HSCRP. Women showed unique anti inflammatory cytokine shifts, pointing to a broader longevity effect. Dave explains why cocoa extract is becoming a foundational nutrient for vascular health rather than a dessert ingredient.

Source: https://www.sciencedaily.com/releases/2025/09/250926135957.htm


• AI Stethoscope for Home Diagnostics

Lapsi Health’s Keikku 2.0 just became the first FDA cleared AI powered digital stethoscope for both clinicians and home users. It records heart and lung sounds, analyzes them instantly, and flags early warning signs before symptoms appear. Dave breaks down why tools like this move you from reactive to predictive medicine and why they belong in every quantified self toolkit.

Source: https://www.prnewswire.com/news-releases/lapsi-health-unveils-keikku-2-0-worlds-first-fda-cleared-digital-stethoscope-with-integrated-ai-scribe-302585083.html?utm_source=chatgpt.com


• Beef Organ Supplements Surge

Beef organ supplements have exploded more than 8,000 percent this year, driven largely by women reporting improvements in energy, hormones, mood, and skin. Liver, kidney, and heart deliver vitamin A, heme iron, B12, copper, and choline that modern diets often lack. Dave covers sourcing concerns, purity standards, and why this shift reflects a move from fear based nutrition to evolutionary nutrition.

Source: https://www.verywellhealth.com/beef-organ-supplement-11710185?utm_source=chatgpt.com


• Spirulina for Collagen and DNA Protection

New research highlights spirulina’s ability to support collagen production, reduce oxidative stress, protect DNA, and improve glucose and lipid balance. It is becoming a staple of eco focused anti aging routines and is driving the viral green stacking trend with chlorella and chlorophyll. Dave explains why spirulina functions as a clean daily defense against oxidative stress.

Source: https://www.news-medical.net/news/20250707/Is-Spirulina-the-Next-Anti-Aging-Superfood.aspx


• Health Data Privacy Reform

A new Senate bill aims to extend HIPAA level protections to wearables, genomic tools, glucose monitors, and wellness apps. The goal is to give users control over who sees their biometrics, how they are stored, and whether they can be sold. Dave outlines why this matters for anyone using Oura, Whoop, CGMs, or genetic testing and why your biology should belong to you and not the cloud.

Source: https://natlawreview.com/article/federal-healthcare-update-november-7-2025


All source links provided for easy reference to the original reporting and research above.


This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality.


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.


New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.


Keywords: cocoa extract, flavanols, heart health, nitric oxide pathways, COSMOS trial, AI stethoscope, digital diagnostics, Keikku device, predictive health tech, beef organ supplements, women’s hormonal health, nutrient dense foods, ancestral nutrition, spirulina benefits, collagen support, oxidative stress defense, green stacking, chlorella pairing, DNA protection, wearable privacy laws, HIPAA reform, biometric data rights, longevity news, biohacking updates


Thank you to our sponsors!


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• Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome

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• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com


Timestamps:

0:00 – Intro

0:19 – Cocoa Extract & Heart Health

1:52 – AI Digital Stethoscope

3:01 – Beef Organ Supplements

4:24 – Spirulina for Longevity

5:42 – Substack Announcement

6:53 – Health Data Privacy Reform

8:23 – Weekly Upgrade Protocol

9:46 – Outro

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Jaksot(1432)

Insulin Resistance, Fasting, Ketones and “Why We Get Sick” – Dr. Ben Bikman with Dave Asprey : 804

Insulin Resistance, Fasting, Ketones and “Why We Get Sick” – Dr. Ben Bikman with Dave Asprey : 804

This episode of Bulletproof Radio runs over 90 minutes and definitely will be worth the time you’ll spend listening. We’re talking about insulin resistance, something that affects half of all adults in the U.S., a lot of our children, and is the leading cause of many common health disorders. Insulin resistance makes you less powerful every day until you get diabetes. Insulin resistance has been a focus for me for more than 10 years. It's part of the Bulletproof Diet and it's part of my book “Fast This Way.” In fact, fasting is very impactful for this. And I've asked Ben Bikman, Ph.D., a biomedical scientist and pathophysiology professor at Brigham Young University, on the show to talk about why insulin resistance is happening. Ben’s research focuses on the role of elevated insulin in regulating obesity and diabetes, including the relevance of ketones in mitochondrial function. “Insulin resistance itself will start to affect the degree to which the mitochondria work,” he says.However, when in balance, insulin is really important to our bodies. “We [speak] about insulin and its role as being a villain, but it's also very much a hero,” Ben says. “It is absolutely essential to survival.”Why is insulin important? It controls blood glucoseEvery cell has insulin receptors, and insulin tells the cell what to do with energy: when to grow, shrink, build or break.Ben brings new insights into what’s going on with insulin resistance and why we must pay attention to it. He synthesizes the latest research and information in his book, “Why We Get Sick: The Hidden Epidemic at the Root of Most Chronic Disease―and How to Fight It.” Due to elevated insulin, elevated stress hormones (cortisol and epinephrine) and inflammation, our bodies can become insulin resistant. Most of the population is insulin resistant and are hyper-insulinemic. This means they have metabolic inflexibility and get stuck in sugar-burning mode and never shift to burning fat, making it nearly impossible to burn or lose weight.“If you are among the majority of people whose brain is yoked to glucose, because your insulin is always high, your glucose is always high, your brain is adapted to only using glucose, and you feel that drop in glucose,” Ben explains. “You will feel the symptoms of hypoglycemia, that carb crash, you will get jittery, you'll get shaky, you'll get anxious, you'll get hungry again even though you just ate 90 minutes ago.”“It's because your brain is so addicted to glucose,” he continues, “that when it starts to drop and in the absence of ketones, which aren't there in that situation, you have no alternative.”Listen on to find out how continuous glucose monitoring can allow you to get a better of sense of your body and what you need to be eating. Ben also gives tips on the best things to eat, how to cook (or what to cook with), fasting (of course) and other ways to protect your body from disease and sickness.This episode will absolutely change your understanding of insulin resistance.Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Cardiovascular Health: https://arterosil.com/dave20/, get a 3-pack and save up to 34% with free shippingNatural Foods: https://paleovalley.com to get 15% offLight Therapy: https://joovv.com/dave, use code DAVE WANT TO UPGRADE YOURSELF EVEN MORE?Learn directly from Dave Asprey in his new membership group https://ourupgradecollective.com. DAVE ASPREY’S NEW BOOK!“Fast This Way: Burn Fat, Heal Inflammation, and Become the High-Performing Human You Were Meant to Be”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

17 Maalis 20211h 36min

How to Identify Your Energy Blockers and Beat Fatigue – Dr. Steven Gundry with Dave Asprey : 803

How to Identify Your Energy Blockers and Beat Fatigue – Dr. Steven Gundry with Dave Asprey : 803

At 70 years young, Dr. Steven Gundry feels and exudes more energy than he did at 40. In this episode of Bulletproof Radio, we’ll talk about how you can make sure you feel the same.Dr. Gundry explains seven deadly energy disruptors that surround us in his new book, “The Energy Paradox: What to Do When Your Get-Up-and-Go Has Got Up and Gone.”“The walking well have become proficient at shouldering a pretty heavy pack of fatigue,” he says in his book. “And it’s taking a toll on multiple fronts—from their personal contentment and fulfilment, to their ability to show up fully in relationships, to their ability to work.”Things like glyphosate, fructose and environmental pollutants often lead to a leaky gut, mitochondrial gridlock and an epidemic of fatigue. That means greater inflammation and less energy from the places we need it most, like our brain and muscles. “We literally are overfed and underpowered,” Dr. Gundry says. “We've been told, and you see it on commercials every day, that you need this energy drink or you need a 30-gram protein drink to get your energy up to take on the day. They literally clog the fuel line and that's our big paradox.We go into these energy disruptors in our conversation that covers the “epidemic” of fatigue and low energy that we often take as a given in our busy day-to-day lives. Today’s episode will give you actionable tips on how to get some of that energy back into your life. “We think that this is something because of our stressful existence or our hard work is just something underlying that we have to deal with or overcome,” Dr. Gundry says. “And it's absolutely not the case at all.”As a practicing cardiologist and retired cardiothoracic surgeon, Dr. Gundry has become a major voice in the world of food toxins and what they do to us. He teaches people how to eat, guiding them on how to get ahead of the problem, not just fixing it after the fact.He’s published more than 300 articles in peer-reviewed journals on using diet and supplements to eliminate heart disease, diabetes, autoimmune disease, and multiple other diseases. He’s also the best-selling author of “The Plant Paradox” and “The Longevity Paradox” books. Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form. WANT TO UPGRADE YOURSELF EVEN MORE?Learn directly from Dave in his new membership group https://ourupgradecollective.com.DAVE ASPREY’S NEW BOOK!“Fast This Way: Burn Fat, Heal Inflammation, and Become the High-Performing Human You Were Meant to Be”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

13 Maalis 20211h 7min

Why Dave Asprey Changed His Mind About Juicing – Junaid Kalmadi of Farmers Juice : 802

Why Dave Asprey Changed His Mind About Juicing – Junaid Kalmadi of Farmers Juice : 802

For a while I was anti-juicing because I found myself consuming a lot of sugar with very few health benefits. But I wanted to flip my own script and introduce you to a brand-new juice company. These juices don’t cause a blood sugar spike. Instead, you get a lot of phytonutrients and the bonus opportunity to support small farmers.In this episode of Bulletproof Radio, I’m talking about juicing with Farmers Juice founder and CEO Junaid Kalmadi. Farmers Juice is the world’s first keto-friendly and functional green juice line with adaptogens, antioxidants and mushrooms. These ingredients boost focus, increase athletic performance, and create a sense of calm.Farmers Juice juices contain no GMOs, artificial colors/preservatives, synthetic fertilizers or toxic persistent pesticides.“Cold-pressed juicing takes one to 1.5 pounds of produce and it separates the liquid from the solid and the juice from the pulp,” Junaid says. “It creates this really concentrated and potent beverage that has all sorts of nutrients of roughly three to five plates of salad in one drink.”And thanks to high pressure processing, Farmers Juice retains all the ingredient goodness. Another bonus that the juices stay fresh for 20 days.Most juice companies use sugar-based ingredients. Instead, Farmers Juice uses a mint, basil, lime, lemon, turmeric, and ginger combination. This gives your tastebuds a tingle every time you drink it and contains only four to five grams of sugar per juice bottle.“I think juice companies selling sugary drinks, even though they have good intentions, contribute to the health care burden of 240 million Americans being overweight or obese and nearly 125 million Americans that are diabetic or prediabetic,” Junaid says. “Juice does not need to be part of the problem; it can be part of the solution.”In addition to supporting human health, Farmers Juice also prioritizes decreasing food waste by partnering up with Alliance of Family Farms to get the “ugly produce” that often gets thrown away. Then, they donate their extra pulp to local farmers for cattle feed. All of their produce comes from small farmers in California.Farmers Juice is good for you, local farmers and the planet. That’s something I can get behind.Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.SPECIAL OFFER FOR BULLETPROOF RADIO LISTENERSGo to https://thefarmersjuice.com/Dave, use code DAVE to get $5 off any box order WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Muscle Stimulation: https://www.powerdot.com/DAVE, use code DAVE to save 20%Autophagy & Anti-Aging: https://spermidinelife.us/dave; use code DAVE25 for 25% off your first month’s orderInfrared Benefits: https://www.sunlighten.com/DAVE. Call the number on the website and mention “Dave Asprey” too get $200 off a cabin sauna, $100 off a Solo system, and free shipping.DAVE ASPREY’S NEW BOOK!“Fast This Way: Burn Fat, Heal Inflammation, and Become the High-Performing Human You Were Meant to Be”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

12 Maalis 202144min

The Metabolism-Cancer Connection & How to Treat It – Dr. Charles Meakin with Dave Asprey : 801

The Metabolism-Cancer Connection & How to Treat It – Dr. Charles Meakin with Dave Asprey : 801

In this episode of Bulletproof Radio, my guest approaches cancer much differently than mainstream medical thinking.Dr. Charles Meakin is Chief Medical Officer for Care Oncology Clinic USA and works specifically on metabolic treatment strategies for curing cancer. He’s also a career biohacker-physician focused on alternative and holistic treatment strategies that he hopes will shape the “fourth field of cancer care.”We talk personalized strategies and specifically about some of the drugs we take for anti-aging that are interesting for cancer care, including stuff that is a little bit shocking to me like statins. We're going to get into that, and if you're interested in metabolism, this show is for you.“Cancer hits one in two men, four in 10 women, and we spend a lot of money on it,” Dr. Meakin says. “And it's still not fixing it.”We’re learning more every day about how cancer manifests and acts in the body. Over the last 10 years, many of the same cancer screening recommendations remain intact, but a lot has changed, such as:Cancer is gradually catching up with cardiovascular disease as the primary cause of death in AmericaThe emergence of obesity as the second most common risk factor for cancerThe increased prevalence of some diseases means many more will experience cancer (1/3 women, 1/2 men)The emergence of HPV virus as a trigger for oral pharyngeal cancer is escalating Dr. Meakin brings holistic alternatives to the normal standard of care: simple balance training programs, nutrition strategies, supplements additive, portable 02, exercise bands, sleep hacks, and more. His options not only improve treatment outcomes for patients, but helps other health conditions in an accessible, inexpensive and safe way. “Our ultimate goal is a paradigm shift to not just let cancer develop, and then try to jump on it in our current ways once it's done, but to work in a better way with prevention and earlier identification,” he explains.Dr. Meakin and I explore the ways we view and treat cancer has changed over time, and how far it still has to go. You’ll learn about developments in oncology like targeted immune therapies, and a new belief called Epigenetic Theory. He doesn’t shy away from hard questions, and that’s what makes this such a great episode.Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Nicotine Gum: https://lucy.co; use code DAVE20 to get 20% off all productsFabric Tech: https://getlambs.com, use code DAVE20 to save 20% on all EMF-protective clothing itemsHigh-Performance Leadership: https://www.humanpotentialinstitute.com/coach-training/DAVE ASPREY’S NEW BOOK!“Fast This Way: Burn Fat, Heal Inflammation, and Become the High-Performing Human You Were Meant to Be”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

10 Maalis 202158min

Why You Have to Heal Your Trauma to Free Your Energy – Tana Amen with Dave Asprey : 800

Why You Have to Heal Your Trauma to Free Your Energy – Tana Amen with Dave Asprey : 800

In this episode of Bulletproof Radio, the topic is something that drives all of us, whether we like it or not: fear and trauma. Tana Amen is just the right guest to talk about this subject. She’s a neurosurgical ICU trauma nurse, vice president of the Amen Clinics, a health and fitness expert and a New York Times best-selling author. She taken on these topics in her new book, “The Relentless Courage of a Scared Child: How Persistence, Grit, and Faith Created a Reluctant Healer.”Tana defines trauma as any event or set of events that occurred in your life that:made you think the world was unsafe,broke your trust in people that you’re surrounded by, andreally caused you to just not trust. We’ve all experienced trauma to varying degrees, so in our conversation we unpack how to identify your responses and access your inner strength.“When we don't heal from trauma, all of that energy is stuck, and it's focused on the wrong things,” Tana says. “You're stuck in this flight or fight thing. You're stuck in this mode of “I need to survive” as opposed to, "I need to just thrive and heal and live life." You can't do that. And that's one of the really big reasons to do it.”Our conversation goes into how trauma impacts your brain function and your healing process. From your biology and psychology to your social circle and spiritual circle, every influence throughout your life can change that process. "We are more beautiful, we are more complex, more interesting because of those broken pieces that we've mended back together and mends just like a scar,” Tana says. “You can be stronger because of that, as long as you heal it, as long as you allow it to set."Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form. DAVE ASPREY’S NEW BOOK!“Fast This Way: Burn Fat, Heal Inflammation, and Become the High-Performing Human You Were Meant to Be”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

5 Maalis 202151min

5 Steps of Neurocycle Can Clean Up Your Mental Mess – Dr. Caroline Leaf with Dave Asprey : 799

5 Steps of Neurocycle Can Clean Up Your Mental Mess – Dr. Caroline Leaf with Dave Asprey : 799

In this episode of Bulletproof Radio, my guest, Dr. Caroline Leaf, has been changing lives through her research into the human mind-brain connection for nearly four decades. “We’ve been sold such a lie that your brain controls you,” she says. The brain isn’t a generator, it’s a responder, so it has to be stimulated. We have the power to change the environment in which the brain thinks, feels and chooses. Dr. Leaf talks about how we can all use self-awareness to better understand and strengthen our minds. Her new book, Cleaning Up Your Mental Mess: 5 Simple, Scientifically Proven Steps to Reduce Anxiety, Stress and Toxic Thinking, shows you ways to use your mind to biohack your brain.It may look different for everyone, but she believes wholeheartedly in our abilities to change through understanding our minds and fostering self-awareness. We can build up our brain health, resilience and strength. Dr. Leaf developed a five-stop process called Neurocycle to help us get there. “The five steps teach you how to grow a healthy thought,” she says.Listen on to learn what these five steps are and how to put them into practice in your own life. “I am absolutely 100% convinced that if we focus more on the mind and understand that we have a level of control that we use online to change our mind, we can change our brain and our body function,” Dr. Leaf says.As a communication pathologist, Dr. Leaf looks at people’s communication tendencies and the roots of those tendencies. She does so by tapping into the depths of the mind, exploring the non-conscious, conscious, and subconscious levels. During her career, she’s conducted research with people who have extreme brain damage, traumatic head injuries and many others, and directed them towards life-altering change. Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Hair Health: https://nutrafol.com, use code DAVENature’s Nootropic: https://gettrukava.com, use code DAVE15 for 15% offReplenish Electrolytes: https://drinklmnt.com/dave, claim your free Sample Pack with $5 shipping DAVE ASPREY’S NEW BOOK!“Fast This Way: Burn Fat, Heal Inflammation, and Become the High-Performing Human You Were Meant to Be”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Maalis 20211h 13min

Tame Your Dragons, Train Your Brain and Take Back Your Happiness – Dr. Daniel Amen with Dave Asprey : 798

Tame Your Dragons, Train Your Brain and Take Back Your Happiness – Dr. Daniel Amen with Dave Asprey : 798

This episode of Bulletproof Radio goes deep into the dragon psyche. No, not “Game of Thrones,” but specifically our inner dragons. “A dragon is an issue you're dealing with, that your brain is listening to, but it's not helping you,” says brain expert Dr. Daniel Amen.These dragons are the ones that “breathe fire on our emotional brain,” like anxiety, depression, grief, loneliness and more (you can find out what yours are at www.knowyourdragons.com).As a physician, double board-certified psychiatrist, professor, and author of 30 books, Dr. Amen has a lot to share about taming the beasts that beset us. In his newest book “Your Brain is Always Listening: Tame the Hidden Dragons that Control Your Happiness, Habits and Hang-ups,” he talks about those dragon origin stories, their triggers, your reactions and how to tame them.He has a lot of tips for how we can step outside of our mind to distance ourselves from the dragon’s fire, like tuning into your pleasure centers, and how to guide your mind to look for what’s right rather than what’s wrong.“It's like a little treasure hunt,” Dr. Amen says. “And I look for even the micro moments. What are the smallest things that happened today that just made me happy? And it sets your dreams up to be more positive. These little habits are so helpful if you can make them part of your everyday life. You literally can train your brain. And when you do, your life is happier.”We talk about the ways past physical and emotional trauma may impact the way we heal, how our dragons are always interacting with other people’s dragons, how this is all affected by the COVID-19 pandemic and much more. Dr. Amen gives practical tools you can use to stop feeling sad, mad, nervous or out of control and start being happier, calmer, and more in control of your own destiny. Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form. SPECIAL OFFER FOR BULLETPROOF RADIO LISTENERShttps://yourbrainisalwayslistening.com book order to get FREE stuff! Ends March 7.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Better-For-You Brews: https://www.flyingembers.com/DAVE, use code DAVE to save 15%Light Therapy: https://joovv.com/dave, use code DAVEBrain Power: https://www.cognibiotics.com/dave, use code DAVE10 DAVE ASPREY’S NEW BOOK!“Fast This Way: Burn Fat, Heal Inflammation, and Become the High-Performing Human You Were Meant to Be”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

2 Maalis 20211h 7min

Mini-Episode: Cool Facts Friday #8

Mini-Episode: Cool Facts Friday #8

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month. Enjoy!Here’s the current lineup for episode #8:Butter texture has changed in Canada.Sleep affects teenagers' mental health.Memories leave unique fingerprints in your brain.EPISODE SPONSOR: ChiliSleep water-based mattress toppers are customizable, climate-controlled sleep solutions. Go to https://www.chilitechnology.com/ASPREY for special discounts.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

26 Helmi 20215min

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