David Sinclair On Extending Human Lifespan & The Science Behind Aging

David Sinclair On Extending Human Lifespan & The Science Behind Aging

Everybody grows old. Everyone dies. But is this scientific fact? Or is it merely a story based on history and our current understanding of biology? What if we instead consider aging as a disease? This begs the question: what is the cure? Welcome to the mind of David Sinclair, PhD, one of the world’s leading scientific authorities on longevity, aging and how to slow its effects. A professor in the Department of Genetics at Harvard Medical School and co-Director of the Paul F. Glenn Center for the Biological Mechanisms of Aging, David obtained his Ph.D. in Molecular Genetics at the University of New South Wales, Sydney in 1995 and worked as a postdoctoral researcher at M.I.T. where, among other things, he co-discovered the cause of aging for yeast. The co-founder of several biotechnology companies, David is also co-founder and co-chief editor of the journal Aging. His work has been featured in a variety of books, documentaries, and media, including 60 Minutes, Nightline and NOVA. He is an inventor on 35 patents, has been lauded as one of the Top 100 Australian Innovators, and made TIME magazine’s list of the 100 most influential people in the world. In addition, David is the author of the forthcoming book, Lifespan: The Revolutionary Science of Why We Age — and Why We Don't Have To* which hits bookstores on Sept. 10 and is currently available for pre-order here*. This is an absolutely fascinating conversation on all things human lifespan, aging and longevity. We begin with the specific scientific mechanisms that contribute to biological degeneration. Then we dive deep into the hard science David and his peers are examining to better understand what contributes to aging and how to prevent it. According to David, the prospect of living to 200+ is not a pipe dream, but a very possible reality. If humans could indeed double lifespan, how would this change how you live? And what does this mean for the future of humanity? This conversation travels deep into the scientific weeds. Perfect for the geeks among us. But it's also grounded in practical takeaways for all of us — because David's work isn't just about extending lifespan. It's about learning how to live as vibrantly and energetically as possible for as long as possible. It’s an honor and a privilege this brilliant man’s pioneering work and wisdom with you today. Plus he's a lovely guy. If you enjoyed my episode with Dr. Valter Longo (RRP #367), a fellow brilliant warrior in the longevity space, then I’m fairly confident you’re going to love this one. So break out that pen and paper, because you're going to want to take notes on this one. I sincerely hope you enjoy the episode. Peace + Plants, Rich

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Ross Edgley Is A Human Poseidon: Lessons From The World’s Longest Non-Stop Swim

Ross Edgley Is A Human Poseidon: Lessons From The World’s Longest Non-Stop Swim

Ross Edgley is a world-renowned extreme adventurer, author, and the star of National Geographic’s “Shark vs. Ross Edgley” This conversation explores Ross’s superhuman feats of endurance, including his recent 510km non-stop swim down the Yukon River. We discuss his unique physiological abilities, training with the Hemsworth brothers, and his race against sharks. He shares his philosophy on finding purpose through struggle and reveals how he consumed 40,000 calories in 24 hours. Ross is a force of nature. And this conversation is an adventure. Enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Today’s Sponsors:  Bon Charge: Use code RICHROLL to save 15% OFF 👉 boncharge.com  LMNT: Get a FREE Sample Pack with any drink mix purchase  👉drinkLMNT.com/RICHROLL On: Enter RichRoll10 at the checkout to get 10% OFF your first order 👉on.com/richroll Whoop: Personalized insights that help you reach your goals 👉join.whoop.com/roll AG1: Get a FREE 1-year supply of Vitamin D3+K2 AND 5 free AG1 Travel Packs 👉drinkAG1.com/richroll Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

19 Aug 20241h 55min

The Voice of Swimming: Olympian Rowdy Gaines on The Sport That Saved His Life

The Voice of Swimming: Olympian Rowdy Gaines on The Sport That Saved His Life

Rowdy Gaines is a three-time Olympic gold medalist, NBC’s voice of swimming, and a living legend in the aquatic world. This conversation explores Rowdy’s extraordinary journey from late-blooming swimmer to world record holder and beloved broadcaster. We dig into his mental resilience through setbacks like the 1980 Olympic boycott and a battle with Guillain-Barré syndrome, his perspective on the evolution of competitive swimming, and his passion for water safety advocacy. He offers a behind-the-scenes look at the Paris Olympics and much more along the way. Rowdy’s infectious enthusiasm is a gift to the sport. He shows everyone how and why we love this sport, which means so much to us both. Enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Today’s Sponsors:  Waking Up: Get a FREE month, plus $30 OFF  👉wakingup.com/RICHROLL Roka: Unlock 20% OFF your order with code RICHROLL 👉ROKA.com/RICHROLL Bon Charge: Use code RICHROLL to save 15% OFF 👉 boncharge.com  Birch: Get 25% off ALL mattresses and 2 free eco-rest pillows 👉BirchLiving.com/richroll This episode is sponsored by Better Help: Listeners get 10% off their first month 👉BetterHelp.com/RICHROLL Meal Planner: For customized plant-based recipes 👉meals.richroll.com Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

12 Aug 20241h 51min

Dr. Ted Schaeffer: All Things Prostate Cancer, Urology, & Men’s Health

Dr. Ted Schaeffer: All Things Prostate Cancer, Urology, & Men’s Health

Dr. Edward Schaeffer is a world-renowned urologist, pioneering robotic surgeon, and Chair of Urology at Northwestern University. This conversation explores the complexities of prostate health and cancer care. We discuss the latest advancements in early detection and treatment and the importance of proactive health management for men. Dr. Schaeffer shares insights on interpreting PSA tests, the role of genetics in prostate cancer risk, and the revolutionary impact of robotic surgery. Along the way, we debunk common myths about prostate health, address the controversies surrounding mass screening, and examine the interplay between lifestyle choices and cancer risk. Dr. Schaeffer is a pioneer in his field. The conversation is enlightening and potentially life-saving. Enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Today’s Sponsors:  AG1: Get a FREE 1-year supply of Vitamin D3+K2 AND 5 free AG1 Travel Packs  👉drinkAG1.com/richroll Peak Design: 20% OFF sleek carry solutions 👉PeakDesign.com/RICHROLL Squarespace: Save 10% off your first purchase of a website or domain 👉 Squarespace.com/RichRoll  On: Enter RichRoll10 at the checkout to get 10% OFF your first order 👉on.com/richroll Meal Planner: For customized plant-based recipes 👉meals.richroll.com Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

8 Aug 20241h 51min

Tom Shadyac: The A-List Filmmaker Who Gave Away Millions & Found Fulfillment Through Service

Tom Shadyac: The A-List Filmmaker Who Gave Away Millions & Found Fulfillment Through Service

Tom Shadyac is the acclaimed director of hit comedies like “Ace Ventura,” “Bruce Almighty,” and “The Nutty Professor,” who walked away from Hollywood success to pursue a life of greater meaning. This conversation explores Tom’s spiritual journey from materialism to service, his life-changing work with Memphis Rox, and his iconoclastic views on consciousness and human interconnectedness. We discuss the illusion of separation, finding purpose through community, and how embracing uncertainty can lead to profound personal growth. Along the way, Tom turns the tables and becomes the interviewer—probing my relationship with ego and uncertainty. Tom’s wisdom and humor are such a treasure. Enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Today’s Sponsors:  Seed: Use code RICHROLL25 for 25% OFF your first order  👉seed.com/RichRoll Bon Charge: Use code RICHROLL to save 15% OFF 👉boncharge.com On: Enter RichRoll10 at the checkout to get 10% OFF your first order 👉on.com/richroll Go Brewing: Use the code Rich Roll for 15% OFF 👉gobrewing.com  Momentous: Save up to 36% OFF your first subscription order of Protein or Creatine + 20% OFF all of my favorite products 👉livemomentous.com/richroll  Meal Planner: For customized plant-based recipes 👉meals.richroll.com Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

5 Aug 20242h 15min

Postcards From Paris: Cody Simpson & Katie Hoff

Postcards From Paris: Cody Simpson & Katie Hoff

Direct from Paris, Rich joins former RRP guests 2x Olympian Katie Hoff, and global singer-songwriter star turned Olympic hopeful Cody Simpson talks big dreams, finding himself, and lessons learned from sport and stage. Plus the latest on the swimming competitions, what it's like behind-the-scenes at the games -- and tons more. Watch on YouTube Browse all episodes of The Rich Roll Podcast at: https://www.richroll.com/all-episodes/ Meal Planner: For customized plant-based recipes 👉meals.richroll.com Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

2 Aug 20241h 11min

Postcards From Paris: Elizabeth Beisel, Katie Hoff, & Chris Morgan

Postcards From Paris: Elizabeth Beisel, Katie Hoff, & Chris Morgan

Direct from Paris, Rich joins 3x Olympian & NBC correspondent Elizabeth Beisel, 2x Olympian & former RRP guest Katie Hoff, and former Swiss Olympic Swimming coach Chris Morgan for a roundtable on the swimming competition, what it's like behind-the-scenes at the games -- and tons more. Watch on YouTube Browse all episodes of The Rich Roll Podcast at: https://www.richroll.com/all-episodes/ Meal Planner: For customized plant-based recipes 👉meals.richroll.com Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

30 Jul 20241h 8min

Rising From Rock Bottom: David Manheim On Addiction, Recovery, Loss & Dopey

Rising From Rock Bottom: David Manheim On Addiction, Recovery, Loss & Dopey

David Manheim is the creator of the Dopey Podcast and a central figure in This American Life’s episode on addiction. This conversation explores the intersection of addiction, recovery, and David’s unconventional approach to healing, which emphasizes raw storytelling and humor. We discuss David’s journey from heroin addict to podcaster, the birth of “Dopey Nation,” the impact of losing his co-host to an overdose, and how vulnerability can lead to profound transformation. He shares insights on addiction treatment and the power of community in recovery. David’s honesty is inspiring. And his conversation is powerful. Enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Today’s Sponsors:  Waking Up: Get a FREE month, plus $30 OFF  👉wakingup.com/RICHROLL  Eight Sleep: Use code RICHROLL to get $350 OFF Pod 4 Ultra 👉eightsleep.com/richroll On: Enter RichRoll10 at the checkout to get 10% OFF your first order 👉on.com/richroll Roka: Unlock 20% OFF your order with code RICHROLL 👉ROKA.com/RICHROLL This episode is brought to you by BetterHelp: Listeners get 10% off their first month 👉 BetterHelp.com/RICHROLL Meal Planner: For customized plant-based recipes 👉meals.richroll.com Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

29 Jul 20241h 53min

The Godfather of Probiotics on Facts Vs Fiction, The Microbiome, & The Power of Microbes To Heal

The Godfather of Probiotics on Facts Vs Fiction, The Microbiome, & The Power of Microbes To Heal

Dr. Gregor Reid is a world-renowned microbiologist, author, and the scientist who defined “probiotics” for the UN/WHO. This conversation explores the world of beneficial microbes and Dr. Reid’s groundbreaking perspective on health, emphasizing probiotics’ power to complement medical approaches. We discuss Dr. Reid’s journey, his scientific philosophy, the potential of probiotics in preventing various conditions, the importance of embracing microbial diversity, the role of fermented foods, finding solutions through microbial interventions, and many other topics. Dr. Reid is a visionary. This exchange is a masterclass in microbial science with far-reaching implications for human and environmental health. Enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Today’s Sponsors:  Bon Charge: Use code RICHROLL to save 15% OFF 👉 boncharge.com Go Brewing: Use the code Rich Roll for 15% OFF your first purchase and get free two-day shipping with 3 six packs or more👉 gobrewing.com  On: Enter RichRoll10 at the checkout to get 10% OFF your first order 👉on.com/richroll Waking Up: Get a FREE month, plus $30 OFF  👉wakingup.com/RICHROLL  Meal Planner: For customized plant-based recipes 👉meals.richroll.com Check out all of the amazing discounts from our Sponsors 👉 richroll.com/sponsors Find out more about Voicing Change Media at voicingchange.media and follow us @voicingchange

25 Jul 20241h 50min

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