Do SSRIs Really Work? Depression Treatment and the Serotonin Debate with Dr Ferghal Armstrong

Do SSRIs Really Work? Depression Treatment and the Serotonin Debate with Dr Ferghal Armstrong

Do SSRIs Really Work? Understanding Depression Treatment and the Serotonin Debate.Are you wondering how SSRIs work for depression treatment or if they’re right for your mental health? Join Dr. Ferghal Armstrong on Cracking Addiction for a myth-busting dive into selective serotonin reuptake inhibitors, the cornerstone antidepressants for mood disorders like severe depression, mild depression, and moderate depression. This episode unpacks the science behind SSRIs, from the chemical imbalance theory of serotonin to the modern role of neuroplasticity in reshaping brain pathways.Dr. Armstrong explains what do SSRIs do, revealing why antidepressant efficacy isn’t instant—those crucial 4-8 weeks are about brain adaptation, not just a serotonin boost. He breaks down clinical trials, showing where SSRIs outperform the placebo effect and where they fall short, especially for mild depression. With antidepressant controversy swirling, learn why side effects like lethargy or emotional numbness affect many, and why only about half of patients see success, highlighting the need for personalized medicine.This video is essential for anyone navigating depression treatment, supporting loved ones, or prescribing antidepressants as clinicians. Dr. Armstrong explores how therapy options and the therapeutic setting amplify results, while the placebo effect can rival SSRIs in some cases. He tackles real-world challenges, from varying response rates to the push for mental health awareness in choosing the right path.Don’t miss this honest look at SSRIs—their strengths, limits, and role in mental health. Dr. Armstrong’s evidence-based insights from clinical trials empower you to make informed decisions about mood disorders and therapy options. Hit play for trustworthy answers and a fresh perspective on the antidepressant controversy!Chapters00:00:00 Introduction: SSRIs and the Mystery of How They Work00:00:41 How SSRIs Affect Serotonin in the Brain00:01:19 Challenging the Chemical Imbalance Theory00:02:09 Do SSRIs Actually Work? Examining the Evidence00:02:53 The Placebo Effect and Study Limitations00:03:31 Real World Response Rates and What They Mean00:04:05 Clinical Judgment and Finding the Right Treatment00:04:44 Setting Realistic Expectations: SSRIs Are Not Magic Bullets00:05:11 Conclusion: The Evolving Science and Role of SSRIs in Depression

Episoder(218)

Special circumstances in OST Part 2

Special circumstances in OST Part 2

In episode 34 of Cracking Addiction we discuss how to manage some of the special circumstances in opioid substation therapy including OST in renal and hepatic impairment, managing polypharmacy complications with OST and managing acute pain whilst a patient is on OST.Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

6 Apr 202218min

Special circumstances in OST Part 1

Special circumstances in OST Part 1

In episode 33 of Cracking Addiction we discuss how to manage some of the special circumstances in opioid substation therapy including vomiting of doses of OST, dealing with intoxicated patients, overdoses of OST and transitioning between Methadone and Suboxone and vice versa.Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

30 Mar 202224min

Naloxone

Naloxone

In episode 32 of Cracking Addiction we discuss the harm reduction intervention of Naloxone and when to consider prescribing this medication, the benefits of take home naloxone and how it saves lives!Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

23 Mar 202221min

Harm Reduction

Harm Reduction

In episode 31 of Cracking Addiction we discuss the harm reduction interventions that we can implement for people who inject drugs to decrease the risks of morbidity and mortality.Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

16 Mar 202226min

Suboxone Part 2

Suboxone Part 2

In episode 30 of Cracking Addiction we discuss the different opioid receptors buprenorphine acts upon and the nature of these effects, the difference between agonists and antagonists, how to start a patient on Suboxone and how to monitor patients on Suboxone and adjust doses.Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

9 Mar 202222min

Suboxone Part 1

Suboxone Part 1

In episode 29 of Cracking Addiction we discuss Suboxone and talk about the components of Suboxone as well as the pharmacology and pharmacokinetics of Suboxone.Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

2 Mar 202218min

LAIB - Top Tips

LAIB - Top Tips

In episode 28 of Cracking Addiction we discuss our practical tips, advice and experience in managing patients on LAIB and share what we have learned.Discussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

23 Feb 202219min

LAIB The Patient Arc

LAIB The Patient Arc

Episode 27 of Cracking Addiction discusses the patient journey on LAIB and how to adequately deal with and manage adjusting doses of LAIB, commencing and ceasing LAIB and ensuring that patients are maintained on LAIB therapyDiscussions and comments in our videos are for informational purposes only and should not replace the advice of your medical professional. Please consult with your doctor before making any changes to your medical treatment or lifestyle.Latest Blogshttps://www.meducate.com.au/blogAbout Meducate ®Meducate provides online education for doctors, clinicians, health professionals and the public.See the website to browse the many different talks and courses available https://www.meducate.com.au

16 Feb 202215min

Populært innen Helse

fastlegen
rss-gukild-johaug
hvordan-har-du-det-mann
relasjonspodden-med-dora-thorhallsdottir-kjersti-idem
leger-om-livet
psykodrama
lydartikler-fra-aftenposten
fryktlos
rss-garne-damer
baarli-og-benjamin-gar-i-terapi
kommentarer-fra-aftenposten
foreldreradet
morten-ramm-lar-kakla-ga-til-du-sovner
rss-puppen-og-lillemor
rss-baarli-og-benjamin-gar-i-terapi
bak-fasaden-en-reise-i-livet-med-sykepleier-ine
hormonelle-frida
klimaks
rss-femihelse
rss-kunsten-a-leve