Part 34 - Dave Feldman on a New Way to Look at Cholesterol, Increasing Health Markers with Fat, and Lowering LDL with a Bad Diet

Part 34 - Dave Feldman on a New Way to Look at Cholesterol, Increasing Health Markers with Fat, and Lowering LDL with a Bad Diet

Dave Feldman is a senior software engineer, lipid and cholesterol investigator, and self-experimenter. He's done a ton of tests on himself over the past 4 years that are making huge waves in the nutrition world. He's helping the world rethink cholesterol and go away from the standard lipid hypothesis to the energy model of how our lipid system works. He's got a great facebook group with an active audience of Lean Mass Hyper Responders. He also travels around the country speaking at conferences

This is a must-listen if you have high LDL cholesterol on a high fat diet or still think that cholesterol is bad. You should also go back and listen to the Ivor Cummins episode in season 1 which gives more of a foundation of knowledge and a bunch of other great info on the topic.

We jump straight in and get technical in the beginning, but stick around. We backtrack and give a lot more context and explain things more clearly. You'll want to keep going even if we get into the weeds because we come out again and go over a lot of useful information and ideas.

This might be the last time you hear from me before the Food Lies Indiegogo campaign ends. This is the last chance to preorder the film and support us. The crowdfunding ends Monday, April 1st at midnight. We have a ways to go, but if we get support in these last few days I think we'll hit our goal. We're still looking for private investors who want to get equity in the film by contributing $15k or more. Please reach out or pass this along if this is a possibility.

Thanks so much, I'm really in love with this community. You've all been so supportive and it looks like we're going to be able to make a super high quality film to get this information out to the world without any outside interests or producers stepping in and influencing the message. Click through the link in the show notes or from FoodLies.org. Now let's hear from the great Dave Feldman.

https://www.indiegogo.com/projects/food-lies-post

Support me on Patreon! http://patreon.com/peakhuman

Show Notes

  • We jump straight into his carnivore experiment
  • He unexpectedly had very high triglycerides after a short time eating only beef products
  • How much things like fasting affect lipid tests
  • New blood test protocol doesn't even ask you to fast even though if you're eating a low carb diet and eat a fatty meal before your blood test you're loading your body temporarily full of triglycerides that will throw off the test
  • We back up a bit and start from the begining with his story of how he got into this cholesterol world
  • Cholesterol is like a distributed systems network
  • The less fat he ate (on a keto ratio) the higher his cholesterol would go. So to lower his cholesterol he would just have to eat more fat before his test
  • This is disrupting the whole standard medical community in 2 ways - they don't think it can change that much over the course of a few days, and it's also the opposite of what they say - they believe more fat should be bad
  • What is the lipid hypothesis?
  • There's no study that really confirms this hypothesis
  • He thinks LDL particles have 2 purposes - first to deliver energy, then to patrol
  • The energy delivery might only be an hour, but they can "patrol" for 2-4 days
  • There's other purposes we haven't even studied much like immune response
  • They can bind to pathogens or can provide alpha tocopherol to reactive oxygen species to turn them into non-reactive products
  • Ambulances, accidents, and aliens
  • All cause mortality and lower LDL does NOT correlate as the standard narrative suggests it should
  • People go on low carb or keto diets and every single thing in their life and lipid panel improves except for this 1 factor - LDL
  • He's been developing what he calls "the energy model" for how lipids work
  • He runs a Facebook group called Lean Mass Hyper Responders for a certain type of people who are lean and fit on a LCHF diet who have super good HDL and triglycerides but super high LDL
  • He polled the group and the vast majority report they feel better to significantly better
  • This "cholesterol is bad" stuff has been hammered into him for so long he may never believe anything otherwise
  • He did a 3.5 hour podcast with Peter Attia (who was in ketosis for 3 years straight) who still looks at cholesterol in the context of a Standard American Diet of trash
  • The group of LMHR people is really interesting to study because they also have super low cardiovascular disease markers
  • The podcast with Peter had some positive outcomes
  • His CIMT (Carotid intima-media thickness) tests that he does regularly to measure his CVD risk factor
  • It actually got a lot better since transitioning from his SAD diet to keto, even though doctors say that's not even possible
  • He then made his score get worse eating white bread, pizza, and a high carb + high fat killer combo diet and gaining a lot of weight
  • He then got it to drop back down again on a keto diet all while having 200+ LDL-C and 2000+ LDL-P
  • Doing exactly the opposite of what the literature says should happen
  • ALSO on the unhealthy Standard American Diet test where he was gaining weight his LDL went back down to good levels that a normal doctor would like WHILE his CIMT score got worse
  • Join the facebook group https://www.facebook.com/groups/LeanMassHyperResponder/
  • He thinks LMHRs experience a higher level of autophagy - they're in a blended fasted state - so it's hard for them to do extended fasts (which is true for me)
  • Your cells need to time to rest and repair
  • Basically, don't always be eating!
  • Let's talk other diets - he has too longtime friends who are vegan and they eat from when they wake until they sleep
  • You can get away with eating trash while you're young - he was skinny as a rail while eating rame, Totinos and chugging Coke
  • For the vast majority of people it eventually catches up to them - it could be alcohol, smoking, excessive sunlight - they seem immune to it and then all of a sudden they fall off
  • We both haven't been sick since being fat adapted/eating a nutrient dense diet
  • I actually got a tiny but sick though, for the first time, by assaulting my body with stressors for 3 days straight and then working out
  • More on how LDL plays a big role in the immune system
  • He has an interesting theory about people with familial hypercholesterolemia having lower total mortality rates despite having high cholesterol because of these high LDL numbers that serve them in times of need. These people have survived pandemics
  • Let's talk N of 1 studies
  • If you're feeling good 24/7 you're probably doing something right and shouldn't worry about a single number or theory
  • Find dave on Twitter http://twitter.com/daveketo
  • His website is http://cholesterolcode.com
  • If you're a lean mass hyper responder (LDL 200 or higher, HDL 80 or higher, and triglycerides 70 or lower) join the group https://www.facebook.com/groups/LeanMassHyperResponder/

Preorder the film here: http://indiegogo.com/projects/food-lies-post

Support me on Patreon! http://patreon.com/peakhuman

Film site: http://FoodLies.org

YouTube: https://www.youtube.com/c/FoodLies

Sapien Movement: http://SapienMovement.com

Follow along:

http://twitter.com/FoodLiesOrg

http://instagram.com/food.lies

http://facebook.com/FoodLiesOrg

Theme music by https://kylewardmusic.com/

Episoder(234)

Part 202 - Stephan Guyenet, PhD on Why Do Humans Overeat?

Part 202 - Stephan Guyenet, PhD on Why Do Humans Overeat?

Stephan J. Guyenet, Ph.D. is an obesity researcher and health writer whose work ties together neuroscience, physiology, evolutionary biology, and nutrition to offer explanations and solutions for our global weight problem. He received a B.S. in biochemistry at the University of Virginia and a Ph.D. in neurobiology at the University of Washington. He is the author of the popular health website, Whole Health Source, and is a frequent speaker on topics of obesity, metabolism, and nutrition. https://www.stephanguyenet.com/about-stephan-guyenet/ BUY THE MEAT NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post SHOW NOTES: (11:16) Our brains determine our food intake and regulate our energy expenditure, in a way that works best in our ancestral environment, but not in our modern environment. (24:33) We consume calories for many reasons, hunger being just one of them. Likewise, satiety is just one of many reasons we stop eating. (34:40) As a rule of thumb, eat a diet of omnivorous whole foods that are lower in calorie density. (49:56) Fiber is not an essential nutrient. (58:35) Nutrient-to-energy is important to health, but once you have adequate intake, there's not much benefit in taking in more. (1:04:46) Most people in the US are more susceptible to obesity than others. Whether or not they actually become obese comes down to the environment they choose. (1:15:31) Blood pressure, on a genetic level, doesn't typically change as one gets older. BUY THE MEAT NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

12 Sep 20231h 26min

Part 201 - Brad Kearns on Finding the Holy Grail of Diet & Lifestyle

Part 201 - Brad Kearns on Finding the Holy Grail of Diet & Lifestyle

Brad Kearns, 58, is a New York Times bestselling author, Guinness World Record setting professional Speedgolfer, #1 USA-ranked Masters age 55-59 track & field high jumper in 2020, and former national champion and #3 world-ranked professional triathlete. He has written twenty books on diet, health, peak performance, and ancestral living, and is a popular speaker, retreat host, and face of the Primal Blueprint online multimedia educational courses. In 2017, The Keto Reset Diet became a New York Times bestseller, and briefly ranked as the #1 overall bestselling book on amazon.com. Brad also hosts the B.rad podcast BUY THE MEAT NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post SHOW NOTES: (09:56) We know what's possible. Now let's shoot for optimal. (21:22) Processed foods disrupt our appetite and satiety hormones, prompting us to overeat. (33:02) Injuries are a sign of overdoing it. (40:56) Homo sapiens are built for near-constant everyday movement. (47:38) Always ask "what's optimal" instead of just "what's possible". (59:54) Raw forms of high-toxin natural plant foods is a potentially problematic category of nutrition. (1:08:26) Our main nutritional challenge is energy toxicity. BUY THE MEAT NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

31 Aug 20231h 24min

Part 200 - My biggest impact fat loss & health tips

Part 200 - My biggest impact fat loss & health tips

This episode features the synthesis of my learnings after doing 200 episodes over the last 5.5 years with many of the world's top doctors & scientists in the health field. Get 80% of the results with 20% of the effort. I've dedicated my life to learning from the best and distilling things down to actionable insights that make it easy for you to get results. Today my sister interviews me in an episode packed with useful info. BUY THE MEAT NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post SHOW NOTES (10:52) The only nutrition plan you'll be able to stick with for the long-term is the one that you enjoy following, and is both nutrient-dense and complete. (24:58) Food Lies was originally a documentary that turned into a six-part series. (29:43) The Sapien Center can be described as a work-from-home health-focused community that makes the journey to health and longevity sustainable and fun. (36:36) Ancestral health combines how humans traditionally ate with modern medicine to prevent and treat chronic disease. (49:25) The main problem with binge eating dietitians and the fat acceptance movement is that they do not understand that there are differences in food. (57:34) Nutrient calories are not the same as energy calories. (1:07:25) Cholesterol is foundational to hormonal health. BUY THE MEAT NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

16 Aug 20231h 20min

Part 199 - Tucker Max on Raising Your Own Food, Providing for Your Family, and the Future of Freedom

Part 199 - Tucker Max on Raising Your Own Food, Providing for Your Family, and the Future of Freedom

Tucker Max has written four New York Times Best Selling books (three that hit #1), which have sold over 4.5 million copies worldwide. He co-founded Scribe Media, the premier professional publishing company that has helped people like David Goggins, Tiffany Haddish and Dan Sullivan publish their books. He was nominated to the Time Magazine 100 Most Influential List in 2009. He received his BA from the University of Chicago in 1998, and his JD from Duke Law School in 2001. He currently lives on a ranch in Dripping Springs, Texas, with his wife Veronica and five children on a homestead ranch where they raise animals, grow their own food, and create sustainable and redundant systems to be self-sufficient. They also helped start an alternative school with their community. BUY THE MEAT NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post SHOW NOTES (14:30) Consuming content endlessly from media personalities is not all that different to binging soap operas. (22:56) Whether or not you develop type 2 diabetes does depend on genetics, but a huge, often-overlooked factor is how your diet looks. (25:51) To Tucker, Waldorf is the ideal homeschooling curriculum for its heavy emphasis on student-led education. (40:15) "The only reason hospitals aren't cesspools of death is because nurses keep it together." (44:37) True sovereignty over your family's livelihood comes down to owning your own sources of food, water, and power. (50:08) Don't be an oldschool doomsday prepper. Control your inputs. (53:43) Taking responsibility for your livelihood—for your food, water, and power, education, and health—creates a sense of urgency in your life. (1:00:35) The COVID-19 crisis taught Tucker to ask himself the two-part question: "What do I believe and why do I believe it?" (1:11:25) Creating your own society starts with the actions you take. Website I mentioned https://www.sovereignhumans.org/ BUY THE MEAT NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

9 Aug 20231h 23min

Part 198 - Mark Sisson on Health From Your Feet On Up

Part 198 - Mark Sisson on Health From Your Feet On Up

Mark Sisson is a renowned health and fitness expert, author, and entrepreneur, celebrated for pioneering the primal lifestyle movements. Once a competitive endurance athlete who achieved a top-five finish in the Ironman World Championship, he is now a successful businessman who founded Primal Kitchen, a purveyor of paleo-friendly foods and supplements, bought by Kraft Heinz in 2018. In addition to his business ventures, he's a bestselling author, with works like "The Primal Blueprint" that promote ancestral eating and exercise habits for health optimization. Recently, Sisson embarked on a new entrepreneurial journey with his son, Kyle, to create Peluva, a better-for-your-body shoe company. He still produces content on his legendary blog, "Mark's Daily Apple," and is absolutely ripped and supremely healthy despite turning 70 next month. Get 10% off Mark's new shoes https://peluva.com/discount/SAPIEN Video version: https://youtu.be/A3jQXP9y5Uo   BUY THE MEAT NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post   SHOW NOTES:   00:00:00 Introduction to Mark Sisson and his shoe company, Peluva.  00:05:00 Talking about NoseToTail.org and the great products  00:10:00 Sisson's insights on modern running shoes and his journey to designing minimalist shoes.  00:15:00 Emphasis on foot health and the drawbacks of cushioned shoes.  00:20:00 Sisson dispels misconceptions about orthotics, advocates minimalist shoes, and introduces Peluva's Strand model.  00:25:00 Sisson discusses human feet evolution, barefoot experience benefits, and safe transition to minimal shoes.  00:30:00 Importance of toe articulation and foot strength training, promoted through Peluva shoes.  00:35:00 Overview of Peluva's different shoe models and their applications. 00:40:00 Critique of cushioned shoes and the benefits of minimalist footwear for foot mobility.  00:45:00 Sisson talks about the role of walking, exercise, and his personal dietary habits.  00:50:00 Sisson outlines his daily routine, metabolic flexibility, and the value of nutrient-dense diets.  00:55:00 Discussion on caloric value of nutrients, protein-centric diets, and metabolic flexibility.  01:00:00 Closing with Sisson promoting Peluva (use code SAPIEN to get 10% off) and his ambition to globally improve foot health. Get 10% off Mark's new shoes https://peluva.com/discount/SAPIEN   BUY THE MEAT NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post       Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

21 Jun 202357min

Part 197 - Chris Knobbe, MD on Why Seed Oils are The Single Most Harmful Ingredient in the Human Diet

Part 197 - Chris Knobbe, MD on Why Seed Oils are The Single Most Harmful Ingredient in the Human Diet

Chris Knobbe, MD, is a physician, researcher, ophthalmologist, public health advocate, and Associate Clinical Professor Emeritus, formerly of the University of Texas Southwestern Medical Center in Dallas, Texas. Dr. Knobbe is known primarily for his research, publications, and presentations connecting Westernized diets and highly polyunsaturated vegetable oils to numerous chronic diseases, including coronary heart disease, hypertension, stroke, cancers, type 2 diabetes, metabolic syndrome, obesity, Alzheimer's disease, autoimmune diseases, and age-related macular degeneration (AMD). Dr. Knobbe's research has focused greatly on the "vegetable oil hypothesis" as the primary driver of overweight and chronic disease. In 2016, Knobbe formally introduced the hypothesis that processed foods and vegetable oils are the primary drivers of AMD, which is the leading cause of irreversible vision loss and blindness in people over the age of 50, worldwide. GET THE MEAT: http://NosetoTail.org FREE SAPIEN FOOD GUIDE: http://sapien.org SHOW NOTES (3:06) Dr. Chris Knobbe's latest publication: Ancestral Diet Revolution (4:54) How Dr. Knobbe left his ophthalmologist practice in 2015 to pursue the topic of seed oils (6:10) The connection between age-related macular degeneration and diet (12:06) Dr. Chris Knobbes impactful use of data and graphs (14:43) Why are seed oils more concerning than other processed foods? (41:31) Dietary changes in populations across the globe and prevalence of disease- the modern displacement of foods (1:04:49) The effect of sugar vs. vegetable oils on the rate of incidence in the United States (1:18:30): Dietary lipid profile is a determinant of tissue phospholipid fatty acid composition and rate of weight gain in rats (https://pubmed.ncbi.nlm.nih.gov/8463854/) (1:26:40) Seeds oils and poor diet as a driver for cancer (1:34:23) Diet and lifestyle is crucial in determining health outcomes regardless of genetics GET THE MEAT: http://NosetoTail.org FREE SAPIEN FOOD GUIDE: http://sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

13 Jun 20231h 34min

Part 196 - Kyle Lasota on Unlocking The Natural Limitless Pill Through Sleep Optimization

Part 196 - Kyle Lasota on Unlocking The Natural Limitless Pill Through Sleep Optimization

On this episode, Brian interviews, Kyle Lasota a Sleep Expert, Biohacker, and YouTuber. Kyle has spent over $150,000 on his own personal health and has helped 1,000's of people transform their sleep. Kyle breaks down exactly how you can start improving your sleep and achieve new levels of performance you previously never had access to. Using these practical biological principles and psychological triggers, he says, anyone can master their sleep. https://www.thesleepadvantage.co/sapien Check out the free video and the course above

25 Mai 20231h 23min

Part 195 - Tara Couture on Incredible Health with the Ultimate Human Lifestyle

Part 195 - Tara Couture on Incredible Health with the Ultimate Human Lifestyle

Tara Couture is one of the most sensational humans the world has to offer. She is a retired Registered Holistic Nutritionist and mother of 3 amazing girls. She and her husband Troy, who works as an ER Doctor, live and manage their homestead farm where they raise and butcher all their own animals. She nourishes her family with nose to tail, regeneratively grown, beyond organic food. Show Notes coming soon!

18 Mai 20231h 30min

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