Podcast 651: Hereditary Angioedema

Podcast 651: Hereditary Angioedema

Contributor: Katie Sprinkel, MD

Educational Pearls:

  • Hereditary angioedema (HA) is an autosomal dominant bradykinin-mediated disease affecting the airway, skin or gastrointestinal tract and typically presents with swelling in the absence of pruritus
  • HA episodes last 3-5 days, typically occur first in childhood or adolescence, and decrease in frequency with aging
  • Airway angioedema is the most dangerous but least common
  • Skin angioedema is usually uncomfortable and should be monitored if involving the face
  • GI angioedema involves nausea, vomiting, and severe abdominal pain
  • No definitive triggers, but episodes may be preceded by a variable prodrome but can include headache, GI symptoms, and even a rash
  • Treatment can include infusion of a C-1 inhibitor, such as Berinert but it is very expensive

References

Busse PJ, Christiansen SC. Hereditary Angioedema. N Engl J Med. 2020 Mar 19;382(12):1136-1148. doi: 10.1056/NEJMra1808012. PMID: 32187470.

Longhurst HJ, Bork K. Hereditary angioedema: an update on causes, manifestations and treatment. Br J Hosp Med (Lond). 2019 Jul 2;80(7):391-398. doi: 10.12968/hmed.2019.80.7.391. PMID: 31283393.

Summarized by John Spartz, MS3 | Edited by Erik Verzemnieks, MD



Avsnitt(1145)

Podcast 875: A Pediatric Case of Myopericarditis

Podcast 875: A Pediatric Case of Myopericarditis

Contributor: Meghan Hurley MD Educational Pearls: Pericarditis is inflammation of the pericardial sac, which can arise from infectious or non-infectious etiologies Myocarditis is inflammation of t...

30 Okt 20236min

Episode 874: Bradyarrhythmias

Episode 874: Bradyarrhythmias

Contributor: Dylan Luyten MD Educational Pearls: What is a Bradyarrhythmia? Also known as a bradyarrhythmia, it is an irregular heart rate that is also slow (below 60 beats per minute). What can c...

23 Okt 20232min

Podcast 873: Intravesical Tranexamic Acid for Gross Hematuria

Podcast 873: Intravesical Tranexamic Acid for Gross Hematuria

Contributor: Aaron Lessen MD Educational Pearls: Tranexamic acid (TXA) is a common medication to achieve hemostasis in a variety of conditions Patients visiting the ED for gross hematuria (between...

16 Okt 20232min

Podcast 872: Preseptal and Orbital Cellulitis

Podcast 872: Preseptal and Orbital Cellulitis

Contributor: Meghan Hurley MD Educational Pearls: What is Cellulitis? A common and potentially serious bacterial skin infection. Caused by various types of bacteria, with Streptococcus and Staphyl...

9 Okt 20234min

Mental Health Monthly #17: Mania

Mental Health Monthly #17: Mania

Contributors: Andrew White MD - Outpatient Psychiatrist; Fellowship Trained in Addiction Psychiatry; Denver Health Travis Barlock MD - Emergency Medicine Physician; Swedish Medical Center Summary In t...

5 Okt 202340min

Podcast 871: Increased Intracranial Pressure and the Cushing Reflex

Podcast 871: Increased Intracranial Pressure and the Cushing Reflex

Contributor: Travis Barlock MD Education Pearls: The Cushing Reflex is a physiologic response to elevated intracranial pressure (ICP) Cushing's Triad: widened pulse pressure (systolic hypertensio...

2 Okt 20233min

On The Streets #15: Hydrofluoric Acid Case Review

On The Streets #15: Hydrofluoric Acid Case Review

Contributors: Kalen Abbott, MD - EM Physician and Medical Director for AirLife Denver Brendan Reiss - Flight Nurse AirLife Denver Matt Spoon - Flight Paramedic AirLife Denver Jordan Ourada - E...

29 Sep 202341min

Episode 870: Advanced Trauma Life Support (ATLS)

Episode 870: Advanced Trauma Life Support (ATLS)

Contributor: Meghan Hurley MD Educational Pearls: What is ATLS? Advanced Trauma Life Support (ATLS) is a systematic and comprehensive approach to the evaluation and management of trauma patients I...

25 Sep 20237min

Populärt inom Vetenskap

p3-dystopia
dumma-manniskor
svd-nyhetsartiklar
allt-du-velat-veta
kapitalet-en-podd-om-ekonomi
det-morka-psyket
dumforklarat
pojkmottagningen
rss-vetenskapsradion-2
rss-vetenskapsradion
rss-ufo-bortom-rimligt-tvivel
sexet
halsorevolutionen
rss-spraket
medicinvetarna
rss-experimentet
vetenskapsradion
paranormalt-med-caroline-giertz
4health-med-anna-sparre
rss-tidslinjen-podcast