The Dirty Secret Behind Ozempic: How It Wrecks Your Gut (Here’s How to Fix It) | Hannah Kleinfeld  : 1265

The Dirty Secret Behind Ozempic: How It Wrecks Your Gut (Here’s How to Fix It) | Hannah Kleinfeld : 1265

For decades, gut health was reduced to yogurt commercials and vague promises from probiotics that barely worked. But what if we’ve been targeting the wrong bugs, using the wrong delivery, and ignoring the true source of chronic inflammation and accelerated aging?

In this thought-provoking episode, Dave sits down with Hannah Kleinfeld, a leader in microbiome innovation, to expose why most probiotics fail—and how one company’s scientifically validated approach could redefine your gut, brain, immune system, and even your metabolism.

You’ll learn how dysbiosis may be wrecking your brain without you knowing it, why your probiotic likely died in your stomach acid, and the secret to rebooting your microbiome after antibiotics, GLP-1 drugs, or years of toxic exposure. This isn’t just about digestion—your gut controls your cravings, energy, sleep, mood, and aging trajectory.

So what’s the one upgrade that can actually reset your gut… for good?

What You’ll Learn in This Episode:

• Why your gut—not your brain—is making most of your decisions

• How 93% of probiotics on the market fail before they reach your intestines

• The “AB 10” protocol that rebuilds your gut after antibiotics or SIBO

• What GLP-1 weight-loss drugs are doing to your microbiome (and how to stop it)

• The shocking gut–brain–heart axis connection you’ve never heard of

• Why inflammation, brain fog, and mood swings may start with leaky gut

• Which probiotic strains are clinically proven to improve cognition and mood

• What to do if you want to eat gluten again—or survive American wheat

• How a fermented papaya concentrate could replace your acid reflux meds

• Why optimizing your gut could extend your lifespan by 40%


***Get 20% off your next purchase by going to https://omnibioticlife.com/pages/dave-asprey/ or omnibioticlife.com/dave***

SPONSORS

-Timeline | Head to https://www.timeline.com/dave to get 10% off your first order.

-Zbiotics | Go to https://zbiotics.com/DAVE for 15% off your first order.

Resources:

Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/

OMNi-BiOTiC's Instagramhttps://www.instagram.com/fatty15/

OMNi-BiOTiC's Website: https://omnibioticlife.com/

2025 Biohacking Conference: https://biohackingconference.com/2025

Danger Coffee: https://dangercoffee.com

Dave Asprey’s Website: https://daveasprey.com

Dave Asprey’s Linktree: https://linktr.ee/daveasprey

Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com

Own an Upgrade Labs: https://ownanupgradelabs.com

Upgrade Labs: https://upgradelabs.com

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com


Timestamps:

00:00 – Trailer

03:15 – Intro

05:05 – Probiotics, Prebiotics, and Postbiotics Explained

08:21 – The Importance of Delivery Mechanisms

17:36 – Addressing SIBO and Gut Health Protocols

31:55 – The Impact of GLP-1 Drugs on Gut Health

39:26 – The Role of Gut Bacteria in Hunger and Fasting

40:01 – Painkillers and Gut Health: A Personal Experience

40:51 – The Dangers of Proton Pump Inhibitors

42:00 – The Importance of Stomach Acid

44:55 – Probiotics for Chronic Conditions

48:38 – The Impact of Glyphosate on Gut Health

57:04 – Alcohol and Gut Bacteria

01:02:01 – New Solutions for Acid Reflux

01:07:57 – The Future of Gut Health and Longevity

01:11:33 – Conclusion and Special Offer

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Avsnitt(1432)

Top Tips from the Trainer of Superheroes – Magnus Lygdbäck : 929

Top Tips from the Trainer of Superheroes – Magnus Lygdbäck : 929

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Get Grounded with Better Foot Function: https://www.vivobarefoot.com/us/daveasprey, use code ASPREY20 to get 20% off your first order and access to the VHealth Barefoot Movement online coursesMattress Temperature Tech: https://www.eightsleep.com/dave, use code DAVE to save $250 on the Pod ProIsometrics for Cardiovascular Health: https://www.zona.com, use code DAVE2022 to get $150 off the Zona PlusIN THIS EPISODE OF THE HUMAN UPGRADE™...…you’ll learn how a trainer of superheroes and superstars combines core principles of fitness, nutrition, structure and balance.Magnus Lygdbäck, a Swedish health and wellness expert, entrepreneur, and lifestyle coach, joins the show to discuss powering your life in ways that most benefit your health and energy.For more than 20 years, he’s trained some of the world’s most recognizable actors, musicians, athletes, artists, and high-performance business entrepreneurs.Musicians like pop stars Katy Perry, Dua Lipa, Harry Styles and Britney Spears. Actors like Gal Gadot for Wonder Woman 1984; Alicia Vikander, for Tomb Raider; Ben Affleck, for Justice League; and many more.He designed Alexander Skarsgård’s incredible transformation for the lead role as a Viking Berserker in the brand new movie, The Northman. Even with his “celebrity trainer” title (which he doesn’t love), Magnus is quick to say, “It's not who you train, it's howyou train.”His Magnus Method training philosophy embraces the “ethos of an athlete.” This all-inclusive approach to performance includes an athlete’s intensity and structure, while also maintaining balance and energy. Time-zone travel, long days of filming, rehearsals, and the constant demands on a celebrity performer’s time means examining all aspects of fueling, rest and recovery. The same applies to the everyday lives of mere mortals.He encourages being open to learning new things and seeking out discomfort so you can grow. “Look at three things,” Magnus recommends. “One, what do I like to do? No. 2, what does my body need? No. 3, what do I want to master or get better at? That should create your weekly programming.”You already know, and Magnus will remind you, that there are absolutely no life shortcuts to being the superhero of your own life.In this conversation, you’ll find out how much time to spend on your workouts (not as much as you think). “What doesn’t happen in the first hour will not happen in the second,” he says frequently. Even for superheroes.Learn more about Magnus Lygdbäck’s journey from hockey player to celebrity trainer.Find out how you can improve your own performance on Magnus’s extensive YouTube channel.Get Magnus’ superhero training programs, nutrition guides, coaching and a community of like-minded people with the Magnus Method app. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

22 Apr 202248min

How a Probiotic Strain Calms Your Body & Brain Stress – Kiran Krishnan, Ph.D. : 927

How a Probiotic Strain Calms Your Body & Brain Stress – Kiran Krishnan, Ph.D. : 927

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Support Immune & Digestive Health: https://justthrivehealth.com, use code ASPREY to get 15% offMeat Sticks and More: https://paleovalley.com/DAVE, use code DAVE to get 15% off your first orderTrigger Autophagy: https://spermidinelife.us/dave, use code DAVE25 for 25% off your first month’s orderSPECIAL OFFER FOR BULLETPROOF RADIO LISTENERS: Go to https://justthrivehealth.com. You’ll find their new line, Joot, and their new Just Calm probiotic for stress management and mood support. Just Calm features the proprietary “psychobiotic” strain BL 1714™ combined with brain-nourishing B vitamins. You’ll also find other products that tackle gut health and inflammation. Use code ASPREY to get a 15% off discount.IN THIS EPISODE OF THE HUMAN UPGRADE™...…you’ll learn about a strain of probiotics called psychobiotics. This strain shows promising effects on stress relief, anxiety, mood, sleep and other important gut-brain axis connections.Microbiologist Kiran Krishnan, Ph.D., explores the human microbiome and how it functions so you can have better gut health. He has an extensive research background in the fields of molecular medicine and microbiology. His particular expertise lies in gut commensal spore bacteria microbiology.He’s been a guest on the show before to educate listeners about probiotics and the connections between your microbiome, inflammation and immune function. This time, he’s sharing exciting research about a probiotic strain that’s tackling the gut-brain axis, called Bifidobacterium longum 1714™.Kiran says, “One really important message that I want people to really wrap their heads around and understand when we're talking about the gut-brain axis is, of course, the gut. A healthy gut is incredibly supportive to the brain. It supports the brain in a number of really important critical functions like recovery, for example, or production of serotonin and dopamine and all these important neurotransmitters, but on the other end of the spectrum, an unhealthy gut is not only not supportive, but it's arguably one of the most toxic things for the brain.”Big topics covered in this episode include:Basic mechanisms by which the gut microbiome can influence neurochemicals and brain inflammationThe gut-brain connection as it relates to stress coping and mental healthHow cortisol and interleukin 6 drive stress response and inflammation in your whole bodyVariables that can cause a breakdown or dysfunction in the psychobiomeTherapeutic interventions, including psychobiotics that can help correct gut-brain axis dysfunctionKiran’s great at explaining the science so you clearly understand what the studies mean and can apply new knowledge to your own biology. He also partners with Just Thrive Health on product research and development.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

15 Apr 20221h 1min

8 Natural Landscapes That Will Restore Your Energy – Emma Loewe : 926

8 Natural Landscapes That Will Restore Your Energy – Emma Loewe : 926

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Mattress Temperature Tech: https://www.eightsleep.com/dave, use code DAVE to save $250 on the Pod ProHealth Upgrades with Custom Lab Testing and Your Data: https://get-base.com/DAVE, use code DAVE to get 20% off your first month of membershipVascular System Protection: https://arterosil.com/DAVE/, save up to 45% a 3-pack to protect your blood vessels from vulnerable plaque.IN THIS EPISODE OF THE HUMAN UPGRADE™...…you’ll learn how nature, human health, and climate activism interconnect. Emma Loewe, environmental journalist and senior sustainability editor at mindbodygreen, joins the show to share how nature can restore all aspects of your health. You’ll find out how you can reap the benefits of specific nature landscapes, wherever you live or roam.You’ll come away from this episode with: Tips on how to combat stress, anxiety and burnout by being outdoors.Actions you can take to conserve the landscapes you care about.Mindset shifts that will change the way you think about the climate crisis.In her new book, “Return to Nature: The New Science of How Natural Landscapes Restore Us,” she’s researched the ways eight distinct nature landscapes improve your physical, mental and spiritual health. Parks & GardensOceans & CoastsMountains & HighlandsForests & TreesIce & SnowDeserts & DrylandsRivers & StreamsCities & Built EnvironmentsEmma shares research-backed ways to explore nature now and protect it for the future, including SRT (stress-reduction theory). This theory says that humans are hardwired to relax while looking at environments that have extensive views, areas to retreat, and essential resources like shade and water.“Return to Nature” also offers:Mindful exercises you can do in short or long chunks of time that allow you to fully experience nature when you’re in it. Additional resources about the eight natural landscapes Emma writes about.Nearly 30 pages of research references! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

12 Apr 202255min

How AI Transforms Your Body’s Biodata Into Real Health Solutions – Lola Priego : 925

How AI Transforms Your Body’s Biodata Into Real Health Solutions – Lola Priego : 925

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Kickstart Autophagy: https://timelinenutrition.com/DAVE, use the code ASPREY10 to get 10% off any planIsometrics for Cardiovascular Health: https://www.zona.com, use code DAVE2022 to get $150 off the Zona PlusBusiness Growth With SEO: https://www.stephanspencer.com, get a FREE consultationSPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS! Go to https://get-base.com/DAVE. Use code DAVE to get 20% off your first purchase.IN THIS EPISODE OF THE HUMAN UPGRADE™...… you’re going to learn about the engineering it takes to build a health data app. You’ll find out how data science, mathematics and predictive analysis look at how biomarkers impact overall wellness. At Base, your own data, along with deep expertise from an advisory board of functional medicine doctors, inform the algorithms. This means you get a distinctly personalized prescription on how to manage your health concerns.Guest Lola Priego, founder and CEO of Base, is an experienced software engineer and former medical student on a mission to help people better understand what is going on in their bodies. She possesses a unique combination of skills to do just that.She studied medicine before transferring to engineering at the Technical University of Madrid and earned a master’s degree in Computer Science and Artificial Intelligence at the Illinois Institute of Technology. While struggling with her own health problems, she identified major pain points in the healthcare system like lack of access to personalized health data. She created Base to solve this issue with a data-driven approach that also provides actionable diet and lifestyle recommendations. Base gets to the root cause of health concerns through analyzing biodata like hormones, nutrition, and vitamin deficiencies to get to the core of why you feel “off.” Base provides testing options that usually are not available at a primary care doctor’s office (they’re often only offered by specialists). Convenience is built into the lab testing process. Base’s blood and saliva tests gets to the root of issues like stress, anxiety, fatigue, and brain fog. Here’s what Base and its accompanying app offer you so you can take control of your own biology and make meaningful life changes:Regular testing tells you what’s going on with your biology.Your own data informs recommendations on how to improve your diet, stress, energy, sleep, and sex drive.You can track your results over time, get help from a team of online experts, and set specific health goals.Because it’s your own health data, there are privacy issues at play you have to know about. Lola explains that security and privacy are built-in design features at Base.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

7 Apr 202258min

The Clear Eye Guide: How to Improve Your Vision Naturally – Claudia Muehlenweg : 924

The Clear Eye Guide: How to Improve Your Vision Naturally – Claudia Muehlenweg : 924

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Strengthen Your Back, Align Your Spine: https://bodyaline.com, use code DAVE100 to save $100 Health Upgrades with Custom Lab Testing and Your Data: https://get-base.com/DAVE, use code DAVE to get 20% off your first month of membershipControl Blood Glucose: https://pendulumlife.com, sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipmentIN THIS EPISODE OF THE HUMAN UPGRADE™...… natural vision expert Claudia Muehlenweg shares interesting knowledge and practical solutions about how you can take better care of your eyes and improve your vision. In this longer episode, You’ll discover ways you can improve your vision through natural methods that start with root causes in your body, including nervous system regulation.You’ll explore bodywork, breathwork, rest, light and movement healing methods.You’ll find out the essential Dos and Don’ts for good eyesight.You’ll get practical suggestions for things you can do right now to offset the effects of screen time.You’ll learn how you can keep your vision sharp throughout your life span. After working to improve her own eyesight, Claudia founded Holistic Vision LLC to help others. Her work is based in the Bates Method. She focuses on finding the root cause of blurry vision instead of using symptomatic treatments like glasses, contacts or surgery that actually can make eyesight worse in the long term. She’s been teaching eyesight improvement since 2009. Her methods can improve presbyopia, myopia, astigmatism, hyperopia, strabismus, convergence insufficiency, and eye diseases such as cataracts, macular degeneration and glaucoma. She also helps people restore clarity after corrective surgeries like LASIK have worn off.Her experience as a yoga teacher brings together complementary practices like myofascial release, breathwork and bodywork that greatly influence holistic vision care and natural vision healing methods.SPECIAL OFFERS FOR THE HUMAN UPGRADE LISTENERS!Step 1: FREE 5 Day Training “See Better in Just 5 Days” April 11-15, 2022. Click here to register.Step 2: FREE “See Clearly Without Glasses or Surgery!” live workshops. Choose one date: April 18, 20 or 22, 2022. Click here to register.Step 3: “Naturally Clear Vision” 10-week online holistic vision improvement program. Click here to register-waitlist only.Just want a freebie? “10 Habits for Happy, Healthy Eyes.” Get the guide here.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

5 Apr 20221h 24min

Upgrade Spotlight: Improve Your Sleep With a Cooler Body Temp – ChiliSleep : 923

Upgrade Spotlight: Improve Your Sleep With a Cooler Body Temp – ChiliSleep : 923

SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS! Be Cool, Get Deeper Sleep: Check out the Dock Pro Sleep System at https://www.chilisleep.com/discount/HUMANUPGRADE20. Use code HUMANUPGRADE20 to save 20%.IN THIS EPISODE OF THE HUMAN UPGRADE™...…you’re listening to a new Upgrade Spotlight series based on what you told me you wanted to hear on this podcast. On one Friday each month, these shorter episodes will feature guests who’ll get right into useful information in a Q&A style. You’ll find out how to improve your energy and upgrade your performance. You’ll also get the latest knowledge about powerful tools and technologies that allow you to change your biology and the environment around you. Introducing ChiliSleep! During this Upgrade Spotlight, you’re going to learn about the physical and mental health benefits of cool sleep and how to hack your sleep with new bed technology.You already know about the physical and psychological effects of not getting good sleep. Whether you’re dangerously sleep-deprived or can’t stop waking up in the middle of the night, struggling to get enough sleep over time can have devastating impacts on your body and mind.Poor sleep increases a person’s risk of developing serious medical conditions, and not getting enough deep sleep increases the chance of high blood pressure; heart attack and stroke; Dementia and Alzheimer’s disease; and Type 2 Diabetes. Tara Youngblood founded ChiliSleep so people could get the coolest sleep ever. Water-based cooling helps your body settle into a just-right temperature that’s just right for you. Your core body temperature should naturally drop every night, but for lots of people for lots of reasons it doesn't. Here are a few of the good things that happen when you regulate your sleep temperature:Cooler temperatures cue your brain to release melatonin and help you fall asleep faster. Sleeping at colder temperatures improves deep sleep and increases muscle recovery.Muscle repair and growth occur during deep sleep and REM sleep stages due to the natural release of growth hormones.Tara creates technologies and apps to help you recover your sleep and your energy. She’s a trained scientist with degrees in Science and Physics who also studied traditional Chinese medicine, Ayurvedic practices, neuroscience, and psychology.She focuses on how your physical body can get better sleep and the important essential link between sleep and mental health.Get Dangerous with Dave's new Remineralized Coffee: https://dangercoffee.comJoin the 8th Annual Biohacking Conference: September 2022! https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

2 Apr 202229min

Home Lab Testing 101: Your Guide to Great Results – Dolce Conde : 922

Home Lab Testing 101: Your Guide to Great Results – Dolce Conde : 922

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Vascular System Protection: https://arterosil.com/DAVE/, save up to 45% a 3-pack to protect your blood vessels from vulnerable plaque.Must-Have Magnesium: https://magbreakthrough.com/DAVE, use code DAVE10 to get a 10% discountBusiness Growth With SEO: https://www.stephanspencer.com, get a FREE consultationSPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS! Go to https://www.knowinglabs.com/DAVE. Use code DAVE to get 20% off every home test kit.IN THIS EPISODE OF THE HUMAN UPGRADE™...… you’re going to get a step-by-step guide to taking accurate labs at home. You’ll learn how to use home test kits effectively to get high-quality results.At-home test kits got more popular in the past few years as people wanted to know more about their personal health data. Knowing your data gives you the power to control your own biology.Some of the biggest value drivers of at-home labs include: Convenience, performance specificity, and being proactive rather than reactive about your symptoms.Dolce Conde co-founded Knowing Labs to support a growing community of people who want to be proactive about their health.Knowing Labs offers reliable laboratory testing directly to consumers in the convenience and privacy of their homes. The kinds of test kits available at Knowing Labs include panels for vitamin D, inflammation, sleep & stress, weight & energy, male and female hormones and wellness, and many more.If you want to use home test kits to find out more about your own data and upgrade your health, here are a few essentials to know:It’s important to choose a certified lab.Knowing Labs is a High Complexity CLIA Certified Laboratory in the State of Texas.CLIA means the Clinical Laboratory Improvement Amendments that regulate laboratory testing.All Knowing Labs testing is done in-house so they have total control over the quality and performance of the services.It’s important to understand the type of at-home test kit you have and how to collect accurate samples. This could be saliva, blood or urine, depending on the kit you choose. For blood samples, this could mean a spot, pipette or home phlebotomist visit.Conde talks about some best practices and troubleshooting tips.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

31 Mars 202248min

How to Ditch Diet Dogma and Simplify Superfoods – Max Lugavere : 921

How to Ditch Diet Dogma and Simplify Superfoods – Max Lugavere : 921

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Non-Tobacco Nicotine Alternative: https://lucy.co, use code DAVE20 to get 20% off your first order of pouches, gums, or lozengesTasty Keto Bread & Chips: https://www.uprisingfood.com/DAVE, use code DAVE to get $10 off the starter bundleFranchise Opportunity: https://ownanupgradelabs.com, to check out the fitness center of the futureIN THIS EPISODE OF THE HUMAN UPGRADE™...…you’ll take a deep dive into the science of healthy eating so that you can know how to leverage food for high energy and performance.Health and science journalist Max Lugavere studies and writes about ways that food and movement fuel you. And allow you some balance and freedom in your choices.He joins the show to round out a body of work that includes his best-selling “Genius Foods,” “The Genius Life” and now his latest to complete the trio: “GENIUS KITCHEN: Over 100 Easy and Delicious Recipes to Make Your Brain Sharp, Body Strong, and Taste Buds Happy.“It's a kitchen and wellness guide,” Max explains. “I didn't want to just make a book of recipes. That would've been too easy. I wanted to make something that was going to stand the test of time and serve as a resource for people."His work was inspired by his mom’s diagnosis with a rare form of dementia in her 50s. He dedicated himself to her care and also began researching how to prevent cognitive decline through nutrition. “Though I began to cook when my mother could no longer cook herself, I realized that culinary literacy (like health literacy) had become yet another aspect of life that we had outsourced,” Max says in “Genius Kitchen.” I became passionate about creating healthy food that is delicious and easy to make."There’s a multi-billion dollar diet industry that makes nutrition confusing and complex. This conversation gets into the value of simple food, how to find your own food philosophy and why Max rejects diet dogma. So this is the episode for you to:-Learn science-backed tactics to improve digestion, increase nutrient extraction and stop common digestive complaints. -Get practical food lists and cooking methods for easy, nutritious meals that work for your performance goals and everyday life.-Find out how to eat like a “genius” with these topics:The upside & downside of plantsProtein quality & muscle maintenanceOrgan meatsFantastic fats & ominous oilsThe shudder of sugarEssential fatty acidsCalcium & the debate about dairyAnd more!More about Max: Max gets his curious on hosting The Genius Life podcast. He appears regularly on the Dr. Oz Show, the Rachael Ray Show, and The Doctors. He’s been featured on NBC Nightly News, The Today Show, and in The New York Times and People Magazine and contributed to Medscape, Vice, Fast Company, CNN, and the Daily Beast. He’s an international speaker who’s presented at events like South by Southwest, TEDx, the New York Academy of Sciences, and the Biohacker Summit in Stockholm, Sweden.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

29 Mars 202259min

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