A Brief History of Rabies

A Brief History of Rabies

Today’s rabies prophylaxis is almost 100% effective at preventing human death from the bite of a rabid animal. How did people come to understand rabies, and then develop a vaccination for it?

Research:

  • Etymologia: Rabies. Emerg Infect Dis [serial on the Internet]. 2012 Jul [date cited]. http://dx.doi.org/10.3201/eid1807.ET1807
  • Velasco-Villa, Andres et al. “The history of rabies in the Western Hemisphere.” Antiviral research vol. 146 (2017): 221-232. doi:10.1016/j.antiviral.2017.03.013
  • Pearce JLouis Pasteur and Rabies: a brief noteJournal of Neurology, Neurosurgery & Psychiatry 2002;73:82.
  • Wendt, Diane. “Surviving rabies 100 years ago.” National Museum of American History. 10/28/2013. https://americanhistory.si.edu/blog/2013/10/surviving-rabies-100-years-ago.html
  • Blancou, Jean. “The Evolution of Rabies Epidemiology in Wildlife.” Director General, Office International des Épizooties. https://www.vetmed.ucdavis.edu/sites/g/files/dgvnsk491/files/inline-files/EVOLUTION_RABIES_EPIDEMIOLOGY_WILDLIFE.pdf
  • Lite, Jordan. “Medical Mystery: Only One Person Has Survived Rabies without Vaccine--But How?.” Scientific American. 10/8/2008. https://www.scientificamerican.com/article/jeanna-giese-rabies-survivor/
  • Zeiler, Frederick A., and Alan C. Jackson. “Critical Appraisal of the Milwaukee Protocol for Rabies: This Failed Approach Should Be Abandoned.” Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques, vol. 43, no. 1, 2016, pp. 44–51., doi:10.1017/cjn.2015.331.
  • Morbidity and Mortality Weekly Report. “Mass Treatment of Humans Exposed to Rabies -- New Hampshire, 1994.” 7/7/1995. https://www.cdc.gov/mmwr/preview/mmwrhtml/00038110.htm
  • Ledesma, Leandro Augusto et al. “Comparing clinical protocols for the treatment of human rabies: the Milwaukee protocol and the Brazilian protocol (Recife).” Revista da Sociedade Brasileira de Medicina Tropical vol. 53 e20200352. 6 Nov. 2020, doi:10.1590/0037-8682-0352-2020
  • Braus, Patricia. "Rabies." The Gale Encyclopedia of Science, edited by Katherine H. Nemeh and Jacqueline L. Longe, 6th ed., vol. 6, Gale, 2021, pp. 3671-3673. Gale In Context: Science, link.gale.com/apps/doc/CX8124402043/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=fb022ca3. Accessed 13 Apr. 2022.
  • Gelfand, Toby. “11 January 1887, the Day Medicine Changed: Joseph Grancher's Defense of Pasteur's Treatment for Rabies.” Bulletin of the History of Medicine, Volume 76, Number 4, Winter 2002, pp. 698-718 (Article). Published by Johns Hopkins University Press https://doi.org/10.1353/bhm.2002.0176
  • Nadal, Deborah. “A Child, A Dog, A Virus and an Anthropologist.” Practicing Anthropology, Fall 2016, Vol. 38, No. 4. Via JSTOR. https://www.jstor.org/stable/10.2307/26539805
  • Botting, Jack H. “Rabies.” From Animals and Medicine: The Contribution of Animal Experiments to the Control of Disease. Open Book Publishers. (2015). Via JSTOR. https://www.jstor.org/stable/j.ctt15m7ng5.7
  • Baer, George M. “The History of Rabies.” From Rabies: Second Edition. Edited by Alan C. Jackson and William H. Wunner. 2007.
  • Jackson, Alan C. “History of Rabies Research.” From: Rabies: Scientific Basis of the Disease and Its Management. Third Edition. 2013.
  • Hansen, Bert. “America's First Medical Breakthrough: How Popular Excitement about a French Rabies Cure in 1885 Raised New Expectations for Medical Progress.” The American Historical Review , Apr., 1998, Vol. 103, No. 2. Via JSTOR. https://www.jstor.org/stable/2649773

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Avsnitt(2599)

Medusa Shipwreck (Part 1)

Medusa Shipwreck (Part 1)

The first episode of this two-parter covers the French mission to Senegal that the frigate Medusa led in 1816. Soon, the mission fell disastrously apart. Research: Amigo, Ignacio. “How a biologist turned amateur sleuth to solve a century-old art riddle.” The Guardian. Oct. 23, 2023. https://www.theguardian.com/artanddesign/2023/oct/27/how-a-biologist-turned-amateur-sleuth-to-solve-a-century-old-art-riddle Barran, Julian. “Théodore Géricault, Illustrations to Alexandre Corréard’s ‘Le Naufrage de La Méduse.’” The Burlington Magazine, vol. 119, no. 889, 1977, pp. 311–310. JSTOR, http://www.jstor.org/stable/878824 Baudelaire, Charles. “WHAT IS ROMANTICISM?” The Salon of 1848. https://writing.upenn.edu/library/Baudelaire-Salon-1848.pdf Burgos, Javier S. “A new portrait by Géricault.” The Lancet Neurology, Volume 20, Issue 2, 90 – 91. https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(20)30479-8/fulltext Burgos, Javier. S. “In search of Théodore Géricault’s lost monomanias.” Metode. June 3, 2024. https://metode.org/issues/article-revistes/in-search-of-theodore-gericaults-lost-monomanias.html Dard, Charlotte Adelaide Picard. “The sufferings of the Picard family after the shipwreck of the Medusa, in the year 1816.” Constable and Co. Edinburgh, Scotland. 1827. Accessed online: https://www.gutenberg.org/files/22792/22792-h/22792-h.htm Dione, Babacar and Mark Banchereau. “France withdraws from Senegal, ending its permanent military presence in West Africa.” AP. July 17, 2025. https://apnews.com/article/senegal-france-military-withdrawal-57d150687e18cd20ac6a6d7194821208 The Editors of Encyclopaedia Britannica. "Treaties of Paris". Encyclopedia Britannica, 23 May. 2025, https://www.britannica.com/event/Treaties-of-Paris-1814-1815 “The Frigate Medusa … “ The Raleigh Minerva. Nov. 4, 1816. https://www.newspapers.com/image/58081420/?match=1&terms=medusa “Gericault.” The Illustrated Magazine of Art, Vol. 2, No. 11 (1853), pp. 282-283 Stable URL: https://www.jstor.org/stable/20538136 Géricault, Théodore. “Cuirassier blessé, quittant le feu.” 1814. Louvre. https://collections.louvre.fr/ark:/53355/cl010059200 Géricault, Théodore. “Race of the Riderless Horses.” 1817. Getty Museum. https://www.getty.edu/art/collection/object/103RH8 Géricault, Théodore. “Race of the Riderless Horses at Rome, Study.” 1817. The Met. https://www.metmuseum.org/art/collection/search/665793 Huet, Marie-Hélène. “The Face of Disaster.” Yale French Studies, no. 111, 2007, pp. 7–31. JSTOR, http://www.jstor.org/stable/20479368 “Loss of the French Frigate Medusa.” Hartford Courant. Oct. 29, 1816. https://www.newspapers.com/image/1105494685/?match=1&terms=medusa Miles, Jonathan. “The Wreck of the Medusa.” Atlantic Monthly Press. 2007. Savigny, Jean Baptiste Henri, and Alexandre Correard. “Narrative of the Voyage to Senegal.” London : Printed for Henry Colburn. 1818. https://archive.org/details/narrativeofvoyag00savirich/page/xiv/mode/2up Smith, Roberta. “Art Review: Oui, Art Tips From Perfidious Albion.” New York Times. Oct. 10, 2003. https://www.nytimes.com/2003/10/10/arts/art-review-oui-art-tips-from-perfidious-albion.html See omnystudio.com/listener for privacy information.

22 Sep 36min

SYMHC Classics: Chesapeake Bay Oyster Wars

SYMHC Classics: Chesapeake Bay Oyster Wars

This 2013 episode covers the years after the Industrial Revolution and the Civil War when the oyster supply became so scarce that people turned to oyster piracy.See omnystudio.com/listener for privacy information.

20 Sep 25min

Behind the Scenes Minis: Math and Falsehoods

Behind the Scenes Minis: Math and Falsehoods

Holly shares a story about Augustin Fresnel's early career. Tracy discusses an article criticizing the Smithsonian and points out its incorrect contents.See omnystudio.com/listener for privacy information.

19 Sep 26min

Maria Amparo Ruiz de Burton

Maria Amparo Ruiz de Burton

Maria Amparo Ruiz de Burton is known as one of the earliest Mexican-American authors published in English, and her life story is tied closely to the Mexican-American war and the establishment of California as a state. Research: Amero, Richard W. “The Mexican-American War in Baja California.” The Journal of San Diego History. Winter 1984, Volume 30, Number 1. https://sandiegohistory.org/journal/1984/january/war/ Annenberg Learner. “Maria Amparo Ruiz de Burton (c. 1832-1895).” https://www.learner.org/series/american-passages-a-literary-survey/masculine-heroes/maria-amparo-ruiz-de-burton-c-1832-1895/ Brink, Jean R. “María Amparo Ruiz de Burton.” EBSCO Knowledge Advantage. 2023. https://www.ebsco.com/research-starters/history/maria-amparo-ruiz-de-burton Contreras, Alicia . "María Amparo Ruiz de Burton". In Oxford Bibliographies in American Literature. 3 Sep. 2025. https://www.oxfordbibliographies.com/view/document/obo-9780199827251/obo-9780199827251-0191.xml. Contreras, Alicia. "'I'll publish your cowardice all over California': Maria Amparo Ruiz de Burton's the squatter and the don in the age of Howells." American Literary Realism, vol. 49, no. 3, spring 2017, pp. 210+. Gale Academic OneFile, link.gale.com/apps/doc/A491311790/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=97ad48d9. Accessed 28 Aug. 2025. Crawford, Kathleen. “María Amparo Ruiz Burton.” The Journal of San Diego History. Summer 1984, Volume 30, Number 3. https://sandiegohistory.org/journal/1984/july/burton/ Diaz, Ella Maria. "Maria Amparo Ruiz de Burton: Critical and Pedagogical Perspectives." Legacy: A Journal of American Women Writers, vol. 22, no. 2, June 2005, pp. 202+. Gale OneFile: Business, link.gale.com/apps/doc/A141999447/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=1c4826f6. Accessed 28 Aug. 2025. Dietrich, Lucas. “A Sensational Job: Maria Amparo Ruiz de Burton, J.B. Lippincott Co., and Commission Printing.” Bibliographical Society of America. Via YouTube. 4/19/2019. https://www.youtube.com/watch?v=Fb6sfXdUyR8 Hedrick, Joan D. "Who Would Have Thought It?" The Women's Review of Books, vol. 13, no. 7, Apr. 1996, p. 6. Gale OneFile: Business, link.gale.com/apps/doc/A19140252/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=c31ab587. Accessed 28 Aug. 2025. Meylor, Megan. “California Nerves.” Texas Studies in Literature and Language, FALL 2020, Vol. 62, No. https://www.jstor.org/stable/10.2307/27117136 Quarstein, John V. “Worden and the Californios.” U.S. Naval Institute. October 2023. https://www.usni.org/magazines/naval-history-magazine/2023/october/worden-and-californios Raab, Josef. “The Imagined Inter-American Community of María Amparo Ruiz de Burton.” Amerikastudien / American Studies, 2008, Vol. 53, No. 1. Via JSTOR. https://www.jstor.org/stable/41158358 Sánchez, Rosaura and Beatriz Pita, editors. “Conflicts of Interest: The Letters of María Amparo Ruiz de Burton.” Arte Publico Press. University of Houston. 2001. Spitzzeri, Paul R. “Article Ten of the Treaty of Guadalupe Hidalgo, 1848.” Homestead Museum Blog. 5/31/2019. https://homesteadmuseum.blog/2019/05/31/article-ten-of-the-treaty-of-guadalupe-hidalgo-1848/ “María Amparo Ruiz, a woman of that century.” Issue 30. 3/8/2017. https://tendenciaelartedeviajar.com/en/2017/03/history/maria-amparo-ruiz-a-woman-of-that-century/ University of Texas Press. “María Amparo Ruiz de Burton and the Conquered Californios: An Interview With Meagan Meylor.” 11/15/2021. https://utpress.utexas.edu/blog/2021/11/15/maria-amparo-ruiz-de-burton-and-the-conquered-californios-an-interview-with-meagan-meylor/ Women & The American Story. “Life Story: María Ruiz de Burton (1832–1895).” The New York Historical Society. https://wams.nyhistory.org/industry-and-empire/expansion-and-empire/maria-ruiz-de-burton/ See omnystudio.com/listener for privacy information.

17 Sep 41min

Augustin Jean Fresnel

Augustin Jean Fresnel

Augustin Fresnel didn’t live a long life, but he contributed significantly to the understanding of light and to the safety of coastlines. Neither of those had anything to do with his career. Research: Anderson, F.L. “Huygens' Principle geometric derivation and elimination of the wake and backward wave.” Sci Rep11, 20257 (2021). https://doi.org/10.1038/s41598-021-99049-7 Aglialoro, Todd. “Jansenism.” Catholic.com. https://www.catholic.com/magazine/print-edition/jansenism Garcia-Atutxa, Igor, et al. “The epistemological impact of Augustin-Jean Fresnel and his wave theory of light in the 19th century.” History of Science and Technology. Vol. 14, No. 1. 2024. https://www.hst-journal.com/index.php/hst/article/view/616 Clingan, Ian C.. "lighthouse". Encyclopedia Britannica, 17 Jan. 2025, https://www.britannica.com/technology/lighthouse Crew, Henry. “The wave theory of light; memoirs of Huygens, Young and Fresnel.” New York. Cincinnati American Book Company. 1900. Accessed online: https://archive.org/details/wavetheoryofligh00crewrich/page/n3/mode/2up Davidson, Michael W. “Augustin-Jean Fresnel (1788-1827).” Molecular Expressions. Florida State University. https://micro.magnet.fsu.edu/optics/timeline/people/fresnel.html The Editors of Encyclopaedia Britannica. "Augustin-Jean Fresnel". Encyclopedia Britannica, 11 Jul. 2025, https://www.britannica.com/biography/Augustin-Jean-Fresnel The Editors of Encyclopaedia Britannica. "François Arago". Encyclopedia Britannica, 22 Feb. 2025, https://www.britannica.com/biography/Francois-Arago “The Genius of Augustin-Jean Fresnel and his Lens.” Ponce Lighthouse & Museum. July 19, 2023. https://www.ponceinlet.org/the-genius-of-augustin-jean-fresnel-and-his-lens/ Herivel, John. "Christiaan Huygens". Encyclopedia Britannica, 4 Jul. 2025, https://www.britannica.com/biography/Christiaan-Huygens. “July 1816: Fresnel’s Evidence for the Wave Theory of Light.” Advancing Physics. American Physical Society. https://www.aps.org/archives/publications/apsnews/201607/physicshistory.cfm Linden, Teri Clark. “A Short Bright Flash: Augustin Fresnel and the Birth of the Modern Lighthouse.” W.W. Norton. 2013. “May 1801: Thomas Young and the Nature of Light.” Advancing Physics. American Physical Society. https://www.aps.org/archives/publications/apsnews/200805/physicshistory.cfm “Napoleon’s Russian campaign: From the Niemen to Moscow.” Napoleon Foundation. https://www.napoleon.org/en/history-of-the-two-empires/timelines/napoleons-russian-campaign-from-the-niemen-to-moscow/ Rehman, Ayaz Ur, and Muhammad Sabieh Anwar. “Light Is a Transverse Wave.” LUMS Syed Babar Ali School of Science and Engineering. August 21, 2018. https://physlab.org/wp-content/uploads/2018/08/LightTransverse-v2.pdf Silliman, Robert H. “Fresnel and the Emergence of Physics as a Discipline.” Historical Studies in the Physical Sciences , 1974, Vol. 4 (1974), pp. 137- University of California Press. https://www.jstor.org/stable/pdf/27757329.pdf Tag, Thomas. “Lens Use Prior to Fresnel.” United States Lighthouse Society. https://uslhs.org/node/1481 See omnystudio.com/listener for privacy information.

15 Sep 36min

SYMHC Classics: Max von Pettenkofer

SYMHC Classics: Max von Pettenkofer

This 2020 episode talks about how Pettenkofer's ideas about cholera's spread weren’t exactly right, but they still had really beneficial impacts on the way we live.See omnystudio.com/listener for privacy information.

13 Sep 31min

Behind the Scenes Minis: All Things Clean

Behind the Scenes Minis: All Things Clean

Tracy talks about her background writing copy for sanitation and cleaning products. She and Holly also discuss how the implementation of the Wells' recommendations could have prevented a lot of illness.See omnystudio.com/listener for privacy information.

12 Sep 29min

William Firth Wells and Mildred Weeks Wells

William Firth Wells and Mildred Weeks Wells

Husband-and-wife team William Firth Wells and Mildred Weeks Wells conducted research that had the potential to make a big difference in the safety of indoor air. But it didn’t really have a significant impact on public health. Research: Associated Press. “Super-Oyster Is On its Way to Dinner Table Bigger and Better Bivalve Sports Pedigree.” 3/13/1927. https://www.loc.gov/resource/sn84020064/1927-03-13/ed-1/?sp=14 “Brought Back to Texas.” The Houston Semi-Weekly Post. 12/26/1889. https://www.newspapers.com/image/1196039760/ Decatur Daily Review. “Scientists Fight Flu Germs with Violet Ray.” 7/30/1936. https://www.newspapers.com/image/94335504/ Evening Star. “Scientific Trap-shooter.” 6/26/1937. https://www.loc.gov/resource/sn83045462/1937-06-26/ed-1/?sp=7&q=William+Firth+Wells&r=0.668,0.557,0.438,0.158,0 Fair, Gordon M. and William Weeks Wells. “Method and Apparatus for Preventing Infection.” U.S. Patent 2,198,867. https://ppubs.uspto.gov/api/pdf/downloadPdf/2198867 Hall, Dominic. “New Center for the History of Medicine Artifact - Wells Air Centrifuge.” Harvard Countway Library. https://countway.harvard.edu/news/new-center-history-medicine-artifact-wells-air-centrifuge “Incubator Is Now Oyster Nurse.” Washington Times. 10/1/1925. https://www.loc.gov/resource/sn84026749/1925-10-01/ed-1/?sp=12 Lewis, Carol Sutton. “Mildred Weeks Wells’s Work on Airborne Transmission Could Have Saved Many Lives—If the Scientific Establishment Listened.” Lost Women of Science Podcast. Scientific American. 5/22/2025. https://www.scientificamerican.com/article/a-public-health-researcher-and-her-engineer-husband-found-how-diseases-can/ Library and Archives Team. “William Firth Wells and Mildred Weeks Wells.” Washington College. https://www.washcoll.edu/people_departments/offices/miller-library/archives-special-collections/archives-blog/Wells%20papers.php Molenti, Megan. “The 60-Year-Old Scientific Screwup That Helped Covid Kill.” Wired. 5/13/2021. https://www.wired.com/story/the-teeny-tiny-scientific-screwup-that-helped-covid-kill/ Perkins JE, Bahlke AM, Silverman HF. Effect of Ultra-violet Irradiation of Classrooms on Spread of Measles in Large Rural Central Schools Preliminary Report. Am J Public Health Nations Health. 1947 May;37(5):529-37. PMID: 18016521; PMCID: PMC1623610. Randall, Katherine and Ewing, E. Thomas and Marr, Linsey and Jimenez, Jose and Bourouiba, Lydia, How Did We Get Here: What Are Droplets and Aerosols and How Far Do They Go? A Historical Perspective on the Transmission of Respiratory Infectious Diseases (April 15, 2021). Available at SSRN: https://ssrn.com/abstract=3829873 Riley, Richard L. “What Nobody Needs to Know About Airborne Infection.” American Journal of Respiratory and Critical Care Medicine. Volume 163, Issue 1. https://www.atsjournals.org/doi/10.1164/ajrccm.163.1.hh11-00 Simon, Clea. “Did a socially awkward scientist set back airborne disease control?” The Harvard Gazette. 3/7/2025. https://news.harvard.edu/gazette/story/2025/03/did-a-socially-awkward-scientist-set-back-airborne-disease-control/ “Texas State News.” McKinney Weekly Democrat-Gazette. 4/17/1890. https://www.newspapers.com/image/65385350/ WELLS MW, HOLLA WA. VENTILATION IN THE FLOW OF MEASLES AND CHICKENPOX THROUGH A COMMUNITY: Progress Report, Jan. 1, 1946 to June 15, 1949, Airborne Infection Study, Westchester County Department of Health. JAMA. 1950;142(17):1337–1344. doi:10.1001/jama.1950.02910350007004 WELLS MW. VENTILATION IN THE SPREAD OF CHICKENPOX AND MEASLES WITHIN SCHOOL ROOMS. JAMA. 1945;129(3):197–200. doi:10.1001/jama.1945.02860370019006 WELLS WF, WELLS MW. AIR-BORNE INFECTION. JAMA. 1936;107(21):1698–1703. doi:10.1001/jama.1936.02770470016004 WELLS WF, WELLS MW. AIR-BORNE INFECTION: SANITARY CONTROL. JAMA. 1936;107(22):1805–1809. doi:10.1001/jama.1936.02770480037010 Wells, W F, and M W Wells. “Measurement of Sanitary Ventilation.” American journal of public health and the nation's health vol. 28,3 (1938): 343-50. doi:10.2105/ajph.28.3.343 Wells, William Firth and Gordon Maskew Fair. Viability of B. coli Exposed to Ultra-Violet Radiation in Air.Science82,280-281(1935).DOI:10.1126/science.82.2125.280.b Wells, William Firth and Mildred Weeks Wells. Measurement of Sanitary Ventilation American Journal of Public Health and the Nations Health 28, 343_350, https://doi.org/10.2105/AJPH.28.3.343 Zimmer, Carl. “Air-Borne: The Hidden History of the Life We Breathe.” Dutton. 2025. See omnystudio.com/listener for privacy information.

10 Sep 46min

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