10 Minute Weekly Biohacking Update : 1347

10 Minute Weekly Biohacking Update : 1347

Upgrade your biology in 10 minutes with this week’s rundown from Dave Asprey. T


This episode covers:

Longevity Scores Are Going Mainstream

Elegant Hoopoe’s new clinics are using 56 biomarkers to track biological aging — and early users are reporting up to six years reversed in under two months. Could scoring systems replace reactive healthcare?

Source: Morningstar via PR Newswire — https://www.morningstar.com/news/pr-newswire/20251014ln95054


AI Heart Scans Spot Trouble Sooner

Hospitals are using machine learning to analyze echocardiograms in real time — making heart diagnostics faster, cheaper, and more accurate, even without top specialists on site.

Source: Crescendo.AI News — https://www.crescendo.ai/news/latest-ai-news-and-updates


Brain Training That Rebuilds Neurotransmitters

McGill’s INHANCE trial shows that 10 weeks of digital training on BrainHQ doesn’t just improve memory — it chemically rejuvenates acetylcholine pathways. That’s measurable neuroplasticity.

Source: Longevity.Technology — https://longevity.technology/news/brain-training-restores-youth-to-aging-minds/


HLTH 2025 Unveils Digital Twins & Real-Time Immune Wearables

This year’s HLTH conference put bio-individuality front and center: AI twins that simulate your biology, hormone-tracking wearables, and apps syncing with EMRs to turn raw data into real decisions.

Source: HLTH Official — https://hlth.com/2025event


One Blood Test, Many Diagnoses

New multi-panel tests rolling out in clinics screen for dozens of diseases from a single draw — boosting compliance, streamlining early detection, and making full-spectrum testing routine.

Source: Instagram Science Updates — https://www.instagram.com/p/DP0oGGTiiT5/


This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality.


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.


New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.


Keywords: longevity score, elegant hoopoe, AI heart scans, brainHQ, acetylcholine, McGill INHANCE trial, HLTH 2025, digital twins, hormone wearables, immune tracking, biological age, multi-panel blood test, early detection, personalized medicine, Dave Asprey, Human Upgrade, biohacking news, health tech, performance medicine, smart diagnostics


Thank you to our sponsors!

-SKILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off.

-EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off.


Resources:

• Danger Coffee: https://dangercoffee.com/discount/dave15

• Dave Asprey’s BEYOND Conference: https://beyondconference.com

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com


Timestamps:

0:00 — Introduction

0:18 — Story 1: Elegant Hoopoe Longevity Score

1:26 — Story 2: AI-Assisted Echocardiograms

2:17 — Story 3: Brain HQ Cognitive Training Study

3:03 — Story 4: Digital Twins at HLTH Conference

4:13 — Story 5: Single Vial Blood Testing

5:04 — Five Day Experiment

5:46 — Closing

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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#86 Your Personal Paleo Code with Chris Kresser

#86 Your Personal Paleo Code with Chris Kresser

The Paleo Diet has been growing in popularity for a while now. So much so that you might consider it an official fad diet. On this episode of Bulletproof Radio, author and Paleo expert, Chris Kresser, makes a valid and fundamentally sound argument about how that is just not the case! After many years of hacking his own health and discovering the distinct formula that works best for his biology, Kresser is eager to share the formula he thinks will work for everyone – and it’s all about personalization. Chris comes on the show to discuss the principles behind his new book, Your Personal Paleo Code. You’ll hear how a desperate health scare became a big motivator for Kresser, his thoughts on epigenetics, Chris' response to some current Paleo Diet criticisms, and a ton more! Have a great listen and happy New Year!   Chris Kresser, M.S., L.Ac, is a practitioner of integrative and functional medicine and the creator of ChrisKresser.com, one of the most respected natural health sites in the world. He developed Your Personal Paleo Code based on more than ten years of research, his own recovery from a debilitating, decade-long illness, and his clinical work with patients. Chris was recently named one of the 50 most influential people in health and fitness by Greatist.com, along with Michelle Obama, Dr. Oz, Dr. Weil, and Deepak Chopra. Paleo Magazine declared Chris’s blog the top science-oriented blog in the Paleo community, and he is a regular health columnist at the Huffington Post. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

31 Dec 201349min

#85 In a State of Ketosis with Dominic D’Agostino

#85 In a State of Ketosis with Dominic D’Agostino

How many of you know what a ketone is? You’ve heard of ketosis, but are you aware of the benefits it can have on your health? On this episode of Bulletproof Radio research scientist Dominic D’Agostino, Ph.D. comes on the show to discuss what it’s like living in ketosis 95% of the time and what he’s discovering through his work developing therapies for diseases like cancer and Alzheiemer’s with ketogenic principles. Also learn how ketones feed your brain, if a ketogenic diet is for everyone, and why MCT oil is so badass!   Dominic D'Agostino, Ph.D. is an Assistant Professor at the College Of Medicine Molecular Pharmacology & Physiology at the University of South Florida. He works to develop and test nutritional and metabolic therapies including ketogenic diets and ketogenic agents for CNS oxygen toxicity (seizures), epilepsy, metabolic disorders, Alzheimer's disease, ALS, muscle wasting and cancer. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

24 Dec 20131h

#84 Hacking Stress with HRV Sense and Ronda Collier

#84 Hacking Stress with HRV Sense and Ronda Collier

“Everything we can do to reduce stress in our lives will lead to great health.” – Ronda Collier   Stress is the new health epidemic only that it’s not new at all. Stress has influenced humans since we were running away from sabre-toothed tigers and living in caves. That same flight-or-fight response still powers our nervous system today – and many of us are not very good at managing it. But that is certainly changeable with generative feedback technology like the HRV Sense™ app. Ronda Collier from SweetWater Health, joins Bulletproof Radio for a second time to discuss the science of Heart Rate Variability and how monitoring it efficiently allows for peak performance and a healthier life! Learn about why the average person should care about HRV, how broccoli is used to qualify fractals, and why self-awareness is key to self-preservation.    Ronda Collier, B.S.E.E., M.A. Psychology holds more than 25 years of experience in high technology product development with a proven track record of delivering leading edge consumer electronic products within both privately held startups and Fortune 500 corporations. She has spent the last 3 years as an independent scholar researching non-invasive health monitoring techniques to improve overall personal well being. This research led to the founding of SweetWater Health, L.L.C. in 2010. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

20 Dec 201349min

#83 Be Real. Be Whole. Be Innovative. With Stew Friedman

#83 Be Real. Be Whole. Be Innovative. With Stew Friedman

How often do you ask yourself what actually matters to you? And do you honestly know what matters to the people around you? Considering both of these questions, how do you align the two?  Stew Friedman  has the answers to these questions and more on this episode of Bulletproof Radio. Stew talks about how he addressed these philosophical questions with science and why data can help us learn the answers. Stew also talks about his new book Baby Bust: New Choices for Men and Women and the fascinating statistics he discovered about why fewer young people expect to be parents these days. There is a ton of good stuff to grab at on this show. Enjoy! Stewart D. Friedman is the Practice Professor of Management at The Wharton School. In 1991, he founded both the Wharton Leadership Program and the Wharton Work/Life Integration Project.  While on academic leave, from 1999 to 2001, he served as the senior executive responsible for leadership development at Ford Motor. There he created the Total Leadership program, which marries the work/life and leadership development fields and is now used around the world.  Working Mother named Friedman one of America’s 25 most influential men to have made things better for working parents.  His widely-cited publications and internationally-recognized expertise led Thinkers50 to select him as one of the “world’s top 50 business thinkers,” and the Families and Work Institute honored him with its Work Life Legacy Award. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

17 Dec 201348min

#82 CILTEP Revealed with Abelard Lindsay

#82 CILTEP Revealed with Abelard Lindsay

From chat rooms to forums, the Internet allows us to communicate anonymously about anything under the sun – the extremely useful and the unfortunately useless. The nootropic stack CILTEP is one of those “extremely useful” gems from an Internet forum via Longecity.org. The creator of this underground nootropic stack comes on the show for an exclusive talk about CILTEP and how it works. CILTEP is  a natural stack designed to improve and maintain brain performance, especially memory, focus, and motivation. On this episode you’ll learn about how it was created and why you should supplement with it for optimal performance. Abelard Lindsay has been doing software development professionally for 20 years. He is currently in his late 30s and in his second year of earning a masters in computer science.  Abelard started investigating alternative medicine and the brain about 10 years ago and was motivated to apply and go back to graduate school in computer science after he began taking the nootropic stack CILTEP because, as he says: “…it was so much easier and enjoyable for me to learn new material… CILTEP made me want to study.” See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

13 Dec 201346min

#81 Revisiting The Calorie Myth with Jonathan Bailor

#81 Revisiting The Calorie Myth with Jonathan Bailor

Have you ever wanted to bash your bathroom scale in with a really large sledgehammer? Bulletproof Radio guest and passionate calorie myth buster, Jonathan Bailor, wants you to do just that! On this episode, Bailor brings back his wealth of knowledge to the show and discusses why counting calories does not make your life better – in fact it can make your life worse. You’ll also hear about the epidemic of girls and calorie counting,  weight loss success rates when counting calories,  and why we should definitely stop freebasing with Oreos!? It’s a great show with tons of information. Enjoy it! Jonathan Bailor is a nutrition and exercise expert and former personal trainer who specializes in using high-quality food and exercise to simplify wellness. He has registered over 25 patents and authored the revolutionary upcoming The Calorie Myth (HarperCollins, 12.31.13). Bailor serves as a Senior Program Manager at Microsoft, hosts a popular syndicated wellness radio show, blogs on The Huffington Post, and consults for organizations around the world. His free 28-day quick-start eating and exercise guide is available at BailorGroup.com. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

10 Dec 201346min

#80 Be More Successful With Gratitude and UJ Ramdas

#80 Be More Successful With Gratitude and UJ Ramdas

‘Tis the season to be grateful! And while that sentiment can often feel a bit disingenuous, it turns out that practicing gratitude can actually make you happier, more effective, and smarter! On this episode of Bulletproof Radio, hypnotist and behavioral biohacker UJ Ramdas talks about the many ways in which gratitude can make you a more successful person. You will learn about the benefits of being resilient, how to put pen to paper, and a short list of things you can do each day to express your gratitude. Oh! And UJ offers a special surprise to Bulletproof listeners! Please enjoy. UJ Ramdas is passionate about bringing together practical psychology and business to create a better world. With a background in Behavioral science, Marketing and Hypnosis, he’s consulted with (several hundred) clients, bringing them from confusion to clarity. Currently based out of Toronto, Canada, he’s a big fan of the wilderness, eastern meditative practices and a good cup of tea. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Dec 201346min

#79 Shamanic Biohacking with Alberto Villoldo

#79 Shamanic Biohacking with Alberto Villoldo

Shamanism and science aren’t often thought of as being allies of one another. Should they be? It turns out that ancient shamans were some of our first brain scientists and biohackers! Expect to take note on this episode of Bulletproof Radio with the inspirational shaman, biohacker, and teacher Alberto Villoldo. There is a ton of useful information to be learned from this talk with Alberto including why a broken diet equals a broken brain, what are the right kinds of medicine plants, and how to, “Pass the salt, bitch!” Trust me; you’ll want to listen. It’s a real honor to have such a wise and humble healer on the show. You won’t be disappointed!  Alberto Villoldo, Ph.D., a psychologist and medical anthropologist, has studied the healing practices of the Amazon and Inka shamans for more than 25 years. While at San Francisco State University, he founded the Biological Self-Regulation Laboratory to study how the mind creates psychosomatic health and disease. Dr. Villoldo directs The Four Winds Society, where he trains individuals throughout the world in the practice of energy medicine. Founder of The Four Winds Society, Alberto instructs individuals throughout the world in the practice of energy medicine.  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

3 Dec 20131h

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