Biohacking News Weekly Update : 1363

Biohacking News Weekly Update : 1363

This episode covers:


• Cocoa Extract Cuts Heart Deaths

A massive COSMOS trial found that older adults taking high flavanol cocoa extract daily saw a 27 percent reduction in cardiovascular deaths along with drops in inflammation markers like HSCRP. Women showed unique anti inflammatory cytokine shifts, pointing to a broader longevity effect. Dave explains why cocoa extract is becoming a foundational nutrient for vascular health rather than a dessert ingredient.

Source: https://www.sciencedaily.com/releases/2025/09/250926135957.htm


• AI Stethoscope for Home Diagnostics

Lapsi Health’s Keikku 2.0 just became the first FDA cleared AI powered digital stethoscope for both clinicians and home users. It records heart and lung sounds, analyzes them instantly, and flags early warning signs before symptoms appear. Dave breaks down why tools like this move you from reactive to predictive medicine and why they belong in every quantified self toolkit.

Source: https://www.prnewswire.com/news-releases/lapsi-health-unveils-keikku-2-0-worlds-first-fda-cleared-digital-stethoscope-with-integrated-ai-scribe-302585083.html?utm_source=chatgpt.com


• Beef Organ Supplements Surge

Beef organ supplements have exploded more than 8,000 percent this year, driven largely by women reporting improvements in energy, hormones, mood, and skin. Liver, kidney, and heart deliver vitamin A, heme iron, B12, copper, and choline that modern diets often lack. Dave covers sourcing concerns, purity standards, and why this shift reflects a move from fear based nutrition to evolutionary nutrition.

Source: https://www.verywellhealth.com/beef-organ-supplement-11710185?utm_source=chatgpt.com


• Spirulina for Collagen and DNA Protection

New research highlights spirulina’s ability to support collagen production, reduce oxidative stress, protect DNA, and improve glucose and lipid balance. It is becoming a staple of eco focused anti aging routines and is driving the viral green stacking trend with chlorella and chlorophyll. Dave explains why spirulina functions as a clean daily defense against oxidative stress.

Source: https://www.news-medical.net/news/20250707/Is-Spirulina-the-Next-Anti-Aging-Superfood.aspx


• Health Data Privacy Reform

A new Senate bill aims to extend HIPAA level protections to wearables, genomic tools, glucose monitors, and wellness apps. The goal is to give users control over who sees their biometrics, how they are stored, and whether they can be sold. Dave outlines why this matters for anyone using Oura, Whoop, CGMs, or genetic testing and why your biology should belong to you and not the cloud.

Source: https://natlawreview.com/article/federal-healthcare-update-november-7-2025


All source links provided for easy reference to the original reporting and research above.


This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality.


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.


New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.


Keywords: cocoa extract, flavanols, heart health, nitric oxide pathways, COSMOS trial, AI stethoscope, digital diagnostics, Keikku device, predictive health tech, beef organ supplements, women’s hormonal health, nutrient dense foods, ancestral nutrition, spirulina benefits, collagen support, oxidative stress defense, green stacking, chlorella pairing, DNA protection, wearable privacy laws, HIPAA reform, biometric data rights, longevity news, biohacking updates


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• 40 Years of Zen: https://40yearsofzen.com


Timestamps:

0:00 – Intro

0:19 – Cocoa Extract & Heart Health

1:52 – AI Digital Stethoscope

3:01 – Beef Organ Supplements

4:24 – Spirulina for Longevity

5:42 – Substack Announcement

6:53 – Health Data Privacy Reform

8:23 – Weekly Upgrade Protocol

9:46 – Outro

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Finding Joy, Building Community and Raising Your Own Pork – Radha Agrawal : 874

Finding Joy, Building Community and Raising Your Own Pork – Radha Agrawal : 874

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Grounding Gear for Your Feet: https://harmony783.com/pages/dave, use code DAVE20 at checkout to get 20% off all grounding footwear and socks.Non-Tobacco Nicotine Alternative: https://lucy.co, use code DAVE20 to get 20% off your first order of pouches, gums, or lozengesGet Salty AF: https://drinklmnt.com/dave, from unflavored to flavor-burst watermelon to classy combos like mango chili.IN THIS EPISODE OF THE HUMAN UPGRADE™️... …you’re going to learn how to biohack joy—and why it’s simpler, and more necessary, than you might think.Radha Agrawal is an author and successful entrepreneur with a singular purpose: to bring people together through joy and genuine human connection.She’s the founder and CEO of Daybreaker, a morning dance, music, and wellness movement that spans five continents. Through Daybreaker, Radha has built a community of more than 500,000 people across the globe who wake up early to dance together.She’s also co-founded, sold, and invested in multiple nine-figure businesses in the wellness space. MTV named her “one of eight women who will change the world,” and she recently toured with Oprah, bringing live music and dance to more than 150,000 people.One of the things Radha has learned over the years is that, for all the superficial connection available in the Digital Age, people are starving for true community—and real human connection seems to be harder to come by now, not easier.Radha thinks one of the biggest things we’re missing is vulnerability.“Every single person listening right now has a backpack full of their own history,” she says. “So, we all carry around this invisible backpack with all of our history in it. [With real community], you start pulling out, ‘My father died in an accident,’ or, ‘this happened,’ or, ‘I got betrayed by this person.’ All of a sudden, there's a depth of tenderness...that’s where community starts.”She goes deeper into the importance of human connection in her book, “Belong: Find Your People, Create Community, and Live a More Connected Life.”This conversation meandered through several unexpected topics, too. Listen on to learn:How to hack your brain for more joy (and how to quantify the joy in your life) – all backed by scienceWhy drugs are a poor substitute for human connection How to build true community in the Digital Age Why dance and music are the future of medicine How Radha went from a small idea to an enormous, successful company—without a single investor The bittersweet reality of being a pig farmer How pain and tragedy can make you stronger, not weaker The importance of forgiveness (and why we have to stop cancelling people) By the end of this podcast, you’ll have practical tools to become a more joyful person. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Nov 20211h 12min

You Control Your Own Karma – Sadhguru : 873

You Control Your Own Karma – Sadhguru : 873

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Nervous System Recovery: https://apolloneuro.com/pages/dave10, sign up to get 10% off an Apollo Neuro deviceSupplement Bioavailability: https://www.quicksilverscientific.com, use code DAVE15 to save 15% on your first order Upgrade Your Magnesium: https://magbreakthrough.com/DAVE, use code DAVE20 to get 20% off. You’ll also get FREE bottles of BiOptimizers’ best-selling products with select purchases. Exclusive discount through November 30, 2021.IN THIS EPISODE OF THE HUMAN UPGRADE™️... Sadhguru, a yogi, mystic, visionary and spiritual master who spreads wisdom around the world, clarifies the meaning of karma (no, it’s not a checklist of good and bad deeds) and explains how much you’re in charge of your own karma. His most recent book, “Karma: A Yogi’s Guide to Crafting Your Destiny,” breaks down the ways in which karma frames our lives.“It’s time to unpack the most overused, abused and yet indispensable world in the spiritual vocabulary of the world,” says Sadhguru in his book. “It is time to examine how karma is connected to some of the most vital areas of human inquiry: the meaning of life and above all, how to live it.”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

2 Nov 202142min

Mini-Episode: Cool Facts Friday #16

Mini-Episode: Cool Facts Friday #16

In this Episode of The Human Upgrade™...Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.Examining the relationship between autoimmunity and pain.Plants up regulate their own autophagy to bring nutrients back in balance.How autophagy supports stressed-out cells.New genes found! Nearly three times more cause obesity than prevent it.EPISODE SPONSOR: Trigger autophagy with Spermidine. Visit https://spermidinelife.us/dave and use code DAVE25 to get 25% off your first month’s order.LISTEN: "Follow" or "subscribe" to The Human Upgrade™ with Dave Asprey on your favorite podcast platform.REVIEW: Go to Apple Podcasts at daveasprey.com/apple and leave a (hopefully) 5-star rating and a creative review.FEEDBACK: Got a comment, idea or question for the podcast? Submit via this form!SOCIAL: Follow @thehumanupgradepodcast on Instagram and Facebook.JOIN: Learn directly from Dave Asprey alongside others in a membership group: https://ourupgradecollective.com.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

29 Okt 202111min

Discover Your ‘Sparketype’ and Meet Your True Self – Jonathan Fields : 872

Discover Your ‘Sparketype’ and Meet Your True Self – Jonathan Fields : 872

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Mattress Temperature Tech: https://www.eightsleep.com/dave, use code DAVE to save $250 on the Pod ProControl Blood Glucose: https://pendulumlife.com, sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipmentHealth Upgrades with Custom Lab Testing and Your Data: https://get-base.com/, use code DAVE to get 20% off your first month of membership.Support Immune & Digestive Health: https://justthrivehealth.com, use code ASPREY to get 15% offIN THIS EPISODE OF THE HUMAN UPGRADE... If you find yourself deeply questioning parts of your life that you haven’t before, you’re not alone. People are asking more existential questions about their lives than they were two years ago, and Jonathan Fields joins the show to guide you through some answers.Jonathan maximizes human potential, especially in the realm of meaningful work. He’s the bestselling author of four books on self-development, most recently “Sparked: Discover Your Unique Imprint for Work that Makes You Come Alive.” He also hosts the popular Good Life Project podcast.“I started into this topic two decades ago,” Jonathan says. “The fact that the last two years have dropped literally the entire world into the biggest existential questioning in generations is not something that I saw coming. But we are in that place, as we sit here depending on the research that you look at, anywhere from 25 to 50 percent of people either have quit their jobs or are in the process of quitting or seriously considering it.”He aims to help people realign the work they’re paid to do, with the actual work that nourishes them through something called Sparketypes. They’re the 10 different archetypes that are sparked by different kinds of work. You may be a maven, maker, scientist, essentialist, performer, sage, warrior, advisor, advocate or nurturer.https://sparketype.com/sparketest/.Get started with the Sparketype quiz at Once you determine your particular Sparketype, it can be easier to find work that lights you up. Knowing your Sparketype also can lessen the fear of a career pivot and show you how to take your enthusiasm for one passion into a different line of work. You then can confidently build a career with a sense of purpose and direction.“[People] may not know what the bargain is that they want to step into,” Jonathan explains. “But what they're getting clear on is the fact that the way that work has made them feel has satisfied certain needs, for sure, security, safety. The more existential needs, which tend to really become more important when we get a little bit further in life, those have generally been set aside. Part of that bargain was maybe later. Later is here.”Enjoy the show!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

28 Okt 20211h 4min

Moving Through Fear’s Allure to Find Inner Peace – Akshay Nanavati  : 871

Moving Through Fear’s Allure to Find Inner Peace – Akshay Nanavati : 871

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Measure Brain Function: Learn more and get a special discounted package at https://wavimed.com/, use code DAVESleep Better on Natural Memory Foam: https://myessentia.com, use code DAVE25 to get 25% off any mattressNon-Tobacco Nicotine Alternative: https://lucy.co, use code DAVE20 to get 20% off your first order of pouches, gums, or lozengesIN THIS EPISODE OF THE HUMAN UPGRADE...Akshay Nanavati’s story of perseverance includes overcoming drug addiction, alcoholism that pushed him to the brink of suicide, depression and PTSD from fighting in Iraq with the U.S. Marines.“That's when I fell in love with the experience of adversity and the struggle because boot camp was terrifying,” Akshay says. “Everything about [it] was terrifying but it was so alluring that I started to look for other ways to confront myself—ultimately to go to war with myself.” He believes that the path to inner peace is the pursuit of a worthy inner war. He went on to build a global business, run ultramarathons, conduct humanitarian work in post-conflict zones, and explore some of the most hostile environments on the planet—from mountains to caves to polar icecaps. “Nature became my playground to explore my fears and ultimately, systematically push through them one inch at a time.”“I craved a high I believed I could only get by living on the edge of life and death,” he says in his book, “Fearvana: The Revolutionary Science of How to Turn Fear Into Health, Wealth and Happiness.” He’s also spent years extensively researching neuroscience, psychology and spirituality. He combined his life experience with that research to write “Fearvana” and infused it with ways to transform fear, and its counterparts stress and anxiety, into something much more positive. His Holiness the Dalai Lama wrote in the book’s foreword, “Fearvana inspires us to look beyond our own agonizing experiences and find the positive side of our lives.” Akshay now teaches people how to overcome their own fears and how to tap into their brain’s superpower—neuroplasticity.Sounds good, but how do you really move through stress and attain growth? First, you have to learn to disidentify with fear and suffering by remembering you are not your thoughts, feelings or experiences, Akshay explains. “You are simply the one who experiences them. Through this process it becomes so much easier to create a life of fulfillment, It’s a lifelong practice and a great pathway to growth.”You can even learn to "suffer well" in the day-to-day context of your human experience.“I couldn't care less when fear shows up,” he says. “What matters to me is what I do with it once it does. I can let go of the construct I have around the fear and accept it for what it is and then choose what I want to do outside of it.”Take a listen for more tips on how to become fearless. Akshay heads to Antarctica in early November 2021. Learn more about his South Pole journey and how to follow along here. Enjoy!Got a comment, idea or question for the podcast? Submit via this form.Be sure to follow or subscribe to The Human Upgrade with Dave Asprey on your favorite podcast platform so you don’t miss an episode!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

26 Okt 20211h 14min

It's Time for an Evolution: The Human Upgrade with Dave Asprey : 870

It's Time for an Evolution: The Human Upgrade with Dave Asprey : 870

Across 10 years and nearly 1,000 episodes, this podcast elevated what you knew about the capabilities of your mind and body.Now, I’m evolving it even further in my plan to upgrade humanity.I invite you to Expand Knowledge, Explore Performance and Embrace Possibility with The Human Upgrade.You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable.People from around the world who elevate what it means to be human. People who choose danger when it's worth it. Just like you. What are you going to learn from these people in the domains of your biology, your body? What are you going to learn about your mind, your thoughts, your habits, the way you show up in the world, and what are you going to learn about the spiritual side of things? The personal development side, that weird space where you wake up and there's a dream in your mind. What does it mean?You can't just focus on one if you want to be an upgraded human. You upgrade all of them. You start with your hardware. Because when your body works right, you have enough electricity. When you have enough electricity, then you can handle the things in your life that need handling. And you can say, "Well, I have some energy left over. What will I do with it?"Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward.Join me on this next evolution to upgrade your mind, body and life. Enjoy! Got a comment, idea or question for the podcast? Submit via this form.Be sure to subscribe to follow or subscribe to The Human Upgrade with Dave Asprey on your favorite podcast platform so you don’t miss an episode!Web: daveasprey.com/Instagram: instagram.com/dave.asprey/Facebook: facebook.com/Daveaspreyofficial/YouTube: youtube.com/c/DaveAspreyBPR/featuredSubscription Box: Dave Asprey BoxMembership Group: The Upgrade CollectiveBlog: Dave Asprey BlogPodcast: The Human Upgrade with Dave AspreySee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

26 Okt 202122min

Tap Into Your Brain’s Full Potential – Patrick Porter, Ph.D., with Dave Asprey : 869

Tap Into Your Brain’s Full Potential – Patrick Porter, Ph.D., with Dave Asprey : 869

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Track Your Health: https://info.insidetracker.com/dave, save 25%Nervous System Recovery: https://apolloneuro.com/dave10 to get 10% off an Apollo Neuro deviceOzone for Healing, Cognition & Performance: http://www.drsozone.com/asprey. Use code UPGRADED10 to save 10% on Dave’s BundleSPECIAL OFFER FOR BULLETPROOF RADIO LISTENERSDiscover how to upgrade your brain fitness: https://braintap.com/daveIN THIS EPISODE OF BULLETPROOF RADIO... You’ll find out how award-winning speaker and author Dr. Patrick Porter developed tools that help your brain access its optimum state through brainwave entrainment. Brainwave entrainment means that different sounds, like Binaural Beats and Isochronic Tones, are pulsed into each of your ears to stimulate your brain into an altered state of consciousness. In a good way! This can improve your focus, energy, relaxation and deep sleep.Using guided meditation, Dr. Porter’s BrainTap device uses a neuro-algorithm to synchronize your brainwaves to a specialized sound. That results in full-spectrum brainwave activity. Each session ensures the brain’s ability to reorganize itself by forming new neural connections, also known as neuroplasticity.Dr. Porter has been a leader in brainwave entertainment tech for more than three decades years. He previously developed the world's first personal sound and light brain-training machine, the mc2, and created a Behavior Repatterning device. He’s written several books about the brain, including: Awaken the Genius: Mind Technology for the 21st Century; Discover the Language of the Mind; Thrive in Overdrive: How to Navigate Your Overloaded Lifestyle; and Awaken Your Flourishing Brain.Dr. Porter continues to widen the scope of what we know about brain capabilities and performance. He says,” We've got this globally world-class brain that can do incredible things for us,” but people often aren’t listening to it.“Once we started being able to measure the brain, we could track how the brain changes,” he says. “We know that every three to five seconds, we need to make a change or interrupt the pattern. If not, the brain will go “bye-bye,” – it's like advertising. The brain only has so much.”BrainTap increases your production of neurotransmitters, leading to a more balanced brainwave state. Even if you can’t stay in that balanced brain state, the feeling of that optimal mode will stick with you and will be within reach at all times. It’s like a flow-state from meditation if you’ve experienced that. But you don’t have to be a meditation expert to experience benefits. BrainTap allows even complete beginners to see immediate progressYou can do the BrainTap sessions at different times of the day when you naturally lose energy, helping you with things like sleep, focus, concentration, mindfulness, memory, stress and anxiety. The sessions also have been shown to increase athletic performance and recovery, and even help with addictions.In this episode, Dr. Porter explains the four elements of BrainTap, including Binaural Beats, Guided Visualization, 0-Cycle Holographic Music and Isochronic Tones. You’ll get to geek out on all the ways your brain affects your body (and vice-versa) and learn what you can do to reach your full brainiac potential. “Our brain actually is always syncing to its environment,” Patrick says. “That's why if it's chaotic {that it’s] causing some disruption. You have to filter it out. You have to learn how to do that.” Don’t miss Dr. Porter’s IG Live! Hacking Your Brain with Light and Sound.Enjoy! Got a comment, idea or question for the podcast? Submit via this form.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

21 Okt 20211h 7min

Be Your Own Hero: Take Risks, Face Your Fears and Choose Courage – Ryan Holiday with Dave Asprey : 868

Be Your Own Hero: Take Risks, Face Your Fears and Choose Courage – Ryan Holiday with Dave Asprey : 868

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Solve Sitting: https://us.harmonidesk.com/, use code DAVE20 and get $20 off any standing deskInfrared Sauna Benefits: https://www.sunlighten.com/DAVE. Call the number on the website and mention “Dave Asprey” to get $200 off a cabin sauna, $100 off a Solo system, and free shippingNon-Tobacco Nicotine Alternative: https://lucy.co, use code DAVE20 to get 20% off your first order of pouches, gums, or lozengesIN THIS EPISODE OF BULLETPROOF RADIO... you’ll discover what it takes to be courageous and heroic in your own life.The Spartans used to build temples to fear. They did so to keep fear close, see its power and ward it off. Modern-day philosopher Ryan Holiday is here to tell you how to do that in your own modern life by using courage to overcome fear.“You can have that reaction [to fear], but then you also realize, if you don't act on it, if you push through, there's often something on the other side of it,” Ryan says. “Or you realize that the more you expose yourself to it, the less scary it is each time and the less perhaps even that you feel that thing.”Everyone experiences fear, but those who can learn to go beyond it will find room for courage. His most recent book, Fear is Calling: Fortune Favors the Brave is compelling and empowering. It breaks down what it means to confront fear, courage and heroism in order to discover your own grace and wisdom. We talk about how to transform fear into courage and the power of choosing the relationship you have with fear.“Man, people get really uncomfortable when something that they were told by their parents, or their church, or their society, or their social media, and all of a sudden, they face profound evidence that it's not true,” Ryan says.Pulling stories from some of the greatest humans in history he talks about how heroism can change the world, and how history can help guide you through contemporary phenomena rooted in fear, like cancel culture and government mandates. This is the first book in Ryan’s new series on the four virtues of the ancient world: courage, temperance, justice, and wisdom. Don’t miss Ryan’s previous visit to Bulletproof Radio and the discussion about stoicism and ego: Modern Stoicism & Crushing your Ego: Ryan Holiday #527Enjoy! Got a comment, idea or question for the podcast? Submit via this form.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

19 Okt 20211h 18min

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