10-Minute Biohacking News Update : 1367

10-Minute Biohacking News Update : 1367

This episode covers:


Nano CBD Pain Relief Without Cognitive Side Effects


A new nano-micelle formulation of CBD called CBD-IN delivers fast, non-addictive pain relief in mice without memory issues, motor impairment or the usual cannabinoid “fog.” Because it crosses the blood brain barrier and directly targets hyperactive pain circuits, it sidesteps many opioid-type drawbacks. Dave explains why precision-designed cannabinoids could reshape chronic pain treatment and longevity support.

Source: https://www.sciencedaily.com/releases/2025/11/251117095652.htm



Moderate Calorie Restriction Slows Biological Aging


A long-term trial from the National Institute on Aging found that cutting calories by about 12% over two years slowed the pace of aging — measured by methylation clocks and metabolic markers — in lean and mildly overweight adults alike. Dave breaks down why small, manageable dietary tweaks can deliver big longevity gains, without crash dieting or extreme fasting.

Source: https://www.nia.nih.gov/news/cutting-calories-may-slow-pace-aging-healthy-adults


FDA Approves AI-Guided Robotic Surgery Trials for Alzheimer’s


The U.S. Food and Drug Administration (FDA) has granted IDE approval for the first robotic microsurgical study targeting early stage Alzheimer’s disease using AI and deep imaging. The trial uses adaptive robotics to target deep brain lymphatic pathways, potentially clearing amyloid/tau deposits with surgical precision. Dave explains why this signals a new era in neurodegeneration – moving from drug-only to machine-assisted brain repair.

Source: https://www.mmimicro.com/ide-approval-for-first-robotic-microsurgery-alzheimers-study/


Antibiotic Reprograms Gut Bacteria to Produce Anti-Aging Molecules


Researchers demonstrated that the veterinary antibiotic cephaloridine can reprogram gut microbes to secrete colanic acid — a molecule linked to better mitochondrial health, reduced gut permeability and improved cholesterol/insulin balance in mice. Dave explores how this could evolve into a pipeline of engineered probiotics that act as internal “longevity factories.”

Source: https://newatlas.com/aging/antibiotic-longevity-microbiome/ (link remains unchanged)


Klotho: The Longevity Protein Nears Clinical Reality


The longevity protein Klotho, known for clearing toxic by-products, calming inflammation and protecting brain/organ networks, is now advancing toward human trials via injectables, oral formats and gene therapy. Dave explains why Klotho is shaping up as a foundational target for next-gen age-reversal strategies and stacking protocols.

Source: https://investingnews.com/longevity-focused-health-fueling-u-s-anti-aging-products-market-projected-to-reach-27-billion-by-2033/ (link remains unchanged)


All source links provided for easy reference to the original reporting and research above.


This episode is essential listening for fans of biohacking, human performance, functional medicine and longevity who want practical tools from Host ­Dave Asprey and the latest breakthroughs shaping the future of health.


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade gives you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence and conscious living.


New episodes are released every Tuesday, Thursday, Friday (audio only) and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.


Keywords: nano CBD, CBD-IN, pain relief research, non opioid pain therapies, chronic pain and aging, caloric restriction aging, methylation clocks, metabolic resilience, AI robotics, Alzheimer’s microsurgery, neurotech advancement, microbiome engineering, colanic acid, longevity probiotics, mitochondrial support, Klotho protein, anti aging gene therapy, cellular rejuvenation, longevity news, biohacking updates


Thank you to our sponsors!



Resources:

• Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome

• Danger Coffee: https://dangercoffee.com/discount/dave15

• My Daily Supplements: SuppGrade Labs (15% Off)

• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)

• Dave Asprey’s BEYOND Conference: https://beyondconference.com

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com

Timestamps:

0:00 — Intro

0:19 — Story 1: Nano CBD for Pain Relief

1:53 — Story 2: Caloric Restriction and Aging

3:20 — Story 3: AI Robotic Surgery for Alzheimer’s

4:50 — Story 4: Microbiome Reprogramming

6:05 — Substack Announcement

7:04 — Story 5: Klotho Longevity Protein

8:39 — Weekly Homework

9:31 — Outro

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Avsnitt(1431)

A WELLTH of Knowledge with Jason Wachob

A WELLTH of Knowledge with Jason Wachob

Jason Wachob is the Founder and CEO of mindbodygreen, the leading independent media brand dedicated to wellness with 12 million monthly unique visitors and the author of WELLTH: How I Learned to Build a Life, Not a Resume. He has been featured in The New York Times, Entrepreneur, Fast Company, Goop, and Vogue. On today's episode of Bulletproof Radio, Dave and Jason talk about meditation, yoga, becoming an entrepreneur, WELLTH, values and motivation, soul-mates and more. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

12 Aug 201654min

Hugs from Dr. Love with Paul Zak

Hugs from Dr. Love with Paul Zak

Paul Zak is a scientist, prolific author and public speaker. His book The Moral Molecule: The Source of Love and Prosperity was published in 2012 and was a finalist for the Wellcome Trust Book Prize. He is the founding Director of the Center for Neuroeconomics Studies and Professor of Economics, Psychology and Management at Claremont Graduate University. Dr. Zak's work on oxytocin and relationships has earned him the nickname "Dr. Love." His current work applies neuroscience to improve marketing and consumer experiences, and to build high performance organizations. On this episode of Bulletproof Radio, Dave and Dr. Zak talk about corporate culture, different reactions to oxytocin, empowerment, trust, decision-making and more. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

9 Aug 20161h 10min

Short Report: Hacking a Concussion with Dave

Short Report: Hacking a Concussion with Dave

On today's episode of Bulletproof Radio, Dave talks about the process he went through to hack a concussion he suffered earlier this year. After three days of stem cell injections and a bout with food poisoning, he passed out "praying to the porcelain god" and hit his head. Here, he talks about his symptoms, the supplements he took to combat them, helpful tech, kids and sports, supporting your mitochondria and more. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

5 Aug 201634min

The Healing Powers of Stem Cells with Dr. Harry Adelson

The Healing Powers of Stem Cells with Dr. Harry Adelson

Dr. Harry Adelson has performed over 3,000 bone marrow and adipose-derived adult stem cell procedures. He's in the company of those most experienced in the world with use of autologous stem cells for the treatment of musculoskeletal pain conditions. He opened Docere Clinics in Salt Lake City in 2002 and his practice is 100% regenerative injection therapies for the treatment of musculoskeletal pain conditions. This episode of the podcast comes days after he gave Dave full-body stem cell treatment, and was recorded inside his lab. Listen to Dave and Dr. Harry talk about fat vs. bone marrow, different kinds of stem cell treatment, culture expansion, prolotherapy, bio-identical hormones and more. Enjoy the show. Dr. Harry will be speaking at this year's Bulletproof Conference, and we're currently offering $200 dollars off of our three-day pass! Get more info at BulletproofConference.com See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

2 Aug 20161h 9min

July Q&A: Aging, Gut Health, Red Meat Substitutes & More!

July Q&A: Aging, Gut Health, Red Meat Substitutes & More!

In this episode of Bulletproof Radio, we've selected the best questions that Bulletproof fans submitted through our voicemail, Facebook and the Bulletproof® Forums, for a great Q&A. Listen to Dave and Bulletproof Coach trainer Dr. Mark Atkinson talk about personal development, aging solutions, gut health and Irritable Bowel Syndrome, red meat and substitutes, handling stress as a student and more. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

29 Juli 20161h 3min

Patrolling with the Health Ranger, Mike Adams

Patrolling with the Health Ranger, Mike Adams

Mike Adams, known as the "Health Ranger," is an outspoken consumer health advocate, award-winning investigative journalist, internet activist and science lab director. He is the founder and editor of NaturalNews.com, the internet's most-trafficked natural health news website. He is also the creator of CounterThink.com, FoodInvestigations.com and several other websites covering natural health topics. On today's episode of Bulletproof Radio, Mike and Dave talk about EPA standards and quality control, glyphosate, water filtration tests, superfoods, future environmental concerns and more. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

26 Juli 20161h 8min

Adventures in Ayahuasca & Psychedelic Medicine with Dennis McKenna

Adventures in Ayahuasca & Psychedelic Medicine with Dennis McKenna

Dennis McKenna's professional and personal interests are focused on the interdisciplinary study of ethnopharmacology and plant hallucinogens. He received his doctorate in 1984 from the University of British Columbia, where his doctoral research focused on ethnopharmacological investigations of the botany, chemistry, and pharmacology of ayahuasca and oo-koo-he, two orally-active tryptamine-based hallucinogens used by indigenous peoples in the Northwest Amazon. He is a founding board member of the Heffter Research Institute and serves on the advisory board of non-profit organizations in the fields of ethnobotany and botanical medicines. On today's episode of Bulletproof Radio, Dennis and Dave talk about psychopharmacology, DMT and the drug culture in the '60s, psychedelic conspiracy theories, microdosing, rescheduling psychedelic drugs, his pursuit of Ayahuasca with the Witoto people and more. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

22 Juli 20161h 10min

Dinner and a Side of Spirituality with Cynthia Pasquella

Dinner and a Side of Spirituality with Cynthia Pasquella

Cynthia Pasquella is a celebrity nutritionist, spiritual leader, media personality and best-selling author. She is the founder and director of the Institute of Transformational Nutrition, the only nutrition certification program that combines nutritional science, psychology, spirituality and coaching skills to people create permanent change in their health and life. Cynthia is also the creator and host of "What You're Really Hungry For," a web series that goes beyond food to examine the true secrets behind having the body, health, and life you've always wanted. On today's episode of Bulletproof Radio, Dave and Cynthia talk about her battles with health and depression, dietary tips, leaving behind a vegan diet, Imposter Syndrome, inner-hunger, sex tips and more. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

19 Juli 20161h 7min

Populärt inom Utbildning

rss-bara-en-till-om-missbruk-medberoende-2
det-skaver
historiepodden-se
alska-oss
nu-blir-det-historia
johannes-hansen-podcast
harrisons-dramatiska-historia
allt-du-velat-veta
roda-vita-rosen
sektledare
not-fanny-anymore
rss-sjalsligt-avkladd
rss-max-tant-med-max-villman
psykologsnack
kungar-och-krig
sa-in-i-sjalen
nar-man-talar-om-trollen
vi-gar-till-historien
rikatillsammans-om-privatekonomi-rikedom-i-livet
sex-pa-riktigt-med-marika-smith