Best of Big Technology: Demis Hassabis On AGI, Deceptive AIs, Building a Virtual Cell

Best of Big Technology: Demis Hassabis On AGI, Deceptive AIs, Building a Virtual Cell

Demis Hassabis is the CEO of Google DeepMind. He joined Big Technology Podcast in early 2025 discuss the cutting edge of AI and where the research is heading. In this conversation, we cover the path to artificial general intelligence, how long it will take to get there, how to build world models, whether AIs can be creative, and how AIs are trying to deceive researchers. Stay tuned for the second half where we discuss Google's plan for smart glasses and Hassabis's vision for a virtual cell. Hit play for a fascinating discussion with an AI pioneer that will both break news and leave you deeply informed about the state of AI and its promising future. --- Enjoying Big Technology Podcast? Please rate us five stars ⭐⭐⭐⭐⭐ in your podcast app of choice. Want a discount for Big Technology on Substack + Discord? Here’s 25% off for the first year: https://www.bigtechnology.com/subscribe?coupon=0843016b Questions? Feedback? Write to: bigtechnologypodcast@gmail.com --- Wealthfront.com/bigtech. If eligible for the overall boosted 3.90% rate offered with this promo, your boosted rate is subject to change if the 3.25% base rate decreases during the 3-month promo period. The Cash Account, which is not a deposit account, is offered by Wealthfront Brokerage LLC ("Wealthfront Brokerage"), Member FINRA/SIPC, not a bank. The Annual Percentage Yield ("APY") on cash deposits as of 12/19/25, is representative, requires no minimum, and may change at any time. The APY reflects the weighted average of deposit balances at participating Program Banks, which are not allocated equally. Wealthfront Brokerage sweeps cash balances to Program Banks, where they earn the variable base APY. Instant withdrawals are subject to certain conditions and processing times may vary. Learn more about your ad choices. Visit megaphone.fm/adchoices

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OpenAI President Greg Brockman on GPT-5.5 “Spud,” AI Model Moats, and Cybersecurity Risks

OpenAI President Greg Brockman on GPT-5.5 “Spud,” AI Model Moats, and Cybersecurity Risks

Greg Brockman is the president and co-founder of OpenAI. Brockman joins Big Technology to discuss GPT-5.5, also known as Spud, and what it means for OpenAI’s next phase of AI development. Tune in to h...

23 Huhti 28min

Are We Too Obsessed With AI Predictions? — With Carissa Véliz

Are We Too Obsessed With AI Predictions? — With Carissa Véliz

Carissa Véliz is an Oxford philosopher and the author of Prophecy: Prediction, Power, and the Fight for the Future, from Ancient Oracles to AI. Véliz joins Big Technology Podcast to discuss whether so...

22 Huhti 54min

Tim Cook Steps Down — With Joanna Stern

Tim Cook Steps Down — With Joanna Stern

Joanna Stern is the ex-WSJ senior personal technology columnist and author of I Am Not a Robot. News of Tim Cook stepping down as CEO of Apple broke as Stern and I were recording a forthcoming episode...

21 Huhti 15min

Jensen On The Ropes, Sam Altman’s Conflicts, Allbirds’ GPU Pivot

Jensen On The Ropes, Sam Altman’s Conflicts, Allbirds’ GPU Pivot

Ranjan Roy from Margins is back for our weekly discussion of the latest tech news. We cover: 1) Nvidia CEO Jensen Huang's pedestrian performance on the Dwarkesh Podcast 2) Jensen's argument about comp...

17 Huhti 58min

The Pentagon's AI Plan + Behind the Anthropic Fight — With Under Secretary of War Emil Michael

The Pentagon's AI Plan + Behind the Anthropic Fight — With Under Secretary of War Emil Michael

Emil Michael is the Under Secretary of War for Research and Engineering at the Pentagon. Michael joins Big Technology to discuss how AI is transforming the Department of War, from targeting systems to...

15 Huhti 59min

Anthropic’s Mythos Dilemma, Violence Against AI, Tokenmaxxing at Meta

Anthropic’s Mythos Dilemma, Violence Against AI, Tokenmaxxing at Meta

Ranjan Roy from Margins is back for our weekly discussion of the latest tech news. We cover: 1) Anthropic's new Mythos preview 2) Is Mythos marketing or a legit breakthrough? 3) The Mythos sandwich gu...

10 Huhti 1h 1min

OpenAI vs. Anthropic's Direct Faceoff + Future of Agents — With Aaron Levie

OpenAI vs. Anthropic's Direct Faceoff + Future of Agents — With Aaron Levie

Aaron Levie is the CEO of Box . Levie joins Big Technology to discuss the battle between OpenAI and Anthropic as their product roadmaps converge around coding, enterprise, and AI agents. Tune in to he...

8 Huhti 58min

More OpenAI Executive Drama, Is Siri Seriously Broken?, Meta’s Elusive Next Hit

More OpenAI Executive Drama, Is Siri Seriously Broken?, Meta’s Elusive Next Hit

M.G. Siegler of Spyglass is back for our monthly tech news discussion. Siegler joins us to discuss latest turmoil inside OpenAI, what the reported tension between CEO Sam Altman and CFO Sarah Friar sa...

6 Huhti 1h 5min

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