Dialing In A High Gain Amp Sound

Chris and Jody walk thru the steps of dealing with High Gain guitar sounds. Which amps are good choices? What if you're using amp sims? Mic'ing an actual cabinet, or using IR's? Why too much gain may hurt you, why you should consider a Tube Screamer, and how the mid's can actually be your friend. It's also not unlikely that there will be some nonsense discussed.