The Gene: Unlocking the Human Code, with Siddhartha Mukherjee

The Gene: Unlocking the Human Code, with Siddhartha Mukherjee

Genetics has revolutionised not just how we think of biology but how we think of ourselves. We are, in the words of one geneticist, the first organism that has ‘learned to read its own instructions’. Now, with the breakthrough of gene-editing technology — whose precision allows us to alter a single letter of DNA — we can now not only decipher but rewrite our genetic code. We may soon be able to treat diseases such as cancer not simply with drugs, but with genetic manipulation. Yet behind this medical revolution lies the prospect of something altogether more worrying. Already, we possess the technology to add to our genetic code at will, and thus create the world’s first generation of ‘transgenic’ humans. As we intervene genetically on ourselves with ever more accuracy, do we risk changing what it means to be human? In a potential quest for the genetically ‘normal’, will we risk annihilating the very diversity and mutations on which evolution depends? These are some of the questions that the Pulitzer... Support this show http://supporter.acast.com/intelligencesquared. See acast.com/privacy for privacy and opt-out information. Learn more about your ad choices. Visit podcastchoices.com/adchoices

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Why Are People Having Fewer Children Than They Want? With Camilla Cavendish

Why Are People Having Fewer Children Than They Want? With Camilla Cavendish

In England and Wales, the total fertility rate fell to 1.39 children per woman in 2025. More than half of the world’s countries and areas are now below the level at which a population replaces itself ...

18 Loka 44min

Archive: Can the Arts Drive Social Change? With Idris Elba, Kwame Kwei-Armah and Yassmin Abdel-Magied

Archive: Can the Arts Drive Social Change? With Idris Elba, Kwame Kwei-Armah and Yassmin Abdel-Magied

In the summer of 2020, as Black Lives Matter protests swept the world, the arts and creative industries faced urgent questions about racism, representation and their role in driving meaningful change....

18 Loka 1h 2min

How One Family Remade Britain: Thomas and Oliver Cromwell, with Miranda Malins

How One Family Remade Britain: Thomas and Oliver Cromwell, with Miranda Malins

Thomas Cromwell helped Henry VIII break with Rome, reshape government and establish the Church of England. A century later, his distant relative Oliver Cromwell helped defeat a king, establish a repub...

15 Loka 57min

Can Europe Defend Itself? Timothy Garton Ash on Europe's Future

Can Europe Defend Itself? Timothy Garton Ash on Europe's Future

Europe’s past is not past. The borders of vanished empires still surface in election results. The European Union and Nato face a world in which Russia is aggressive, America is less dependable and Eur...

13 Loka 34min

Can Pigs Really Appreciate Bach? Katherine Rundell Live

Can Pigs Really Appreciate Bach? Katherine Rundell Live

Katherine Rundell has dazzled millions of readers globally with her writing on fantastical beasts. In her bestselling book The Golden Mole, she profiled some of the world’s most extraordinary endanger...

12 Loka 1h 23min

Archive: What Are the Chances We Exist at All? With Brian Cox and Alice Roberts

Archive: What Are the Chances We Exist at All? With Brian Cox and Alice Roberts

Who are we? Why are we here? Are we alone in the universe? How did we become the creatures that we are? How might we further evolve? These are some of the big questions that Brian Cox and Alice Robert...

11 Loka 1h 3min

What James Baldwin Can Teach Us About the World Today

What James Baldwin Can Teach Us About the World Today

On the 70th anniversary of the publication of Giovanni’s Room, James Baldwin’s seminal novel about sexuality, race and myth in America, Booker Prize-winning writer Ben Okri joined us to reflect on the...

10 Loka 1h 17min

The Age of Change with Jeremy Hunt, in Partnership with IBM

The Age of Change with Jeremy Hunt, in Partnership with IBM

In this episode, Kamal was joined by Jeremy Hunt, former Chancellor of the Exchequer, Lawrence Tallon, Chief Executive of the Medicines and Healthcare products Regulatory Agency (MHRA), and Dr. Angela...

6 Loka 43min

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