Do Androgen Receptors Downregulate From Continuous Steroid Use?

Do Androgen Receptors Downregulate? There is a very common misconception in the bodybuilding community that androgen receptors downregulate during a steroid cycle, or during long-term steroid use. A plateau in muscle gain is commonly attributed to this “androgen receptor downregulation”. If you've ever cycled anabolics, you can also attest to the fact that during a new cycle the gains always seem to come within the first 8 weeks or so, and then the weeks following that it is typical to notice a blatant diminishing returns effect.… Learn more about your ad choices. Visit megaphone.fm/adchoices