Epigenetic Origins Of Heterogeneity And Disease (Andrew Pospisilik)
Epigenetics Podcast19 Helmi 2020

Epigenetic Origins Of Heterogeneity And Disease (Andrew Pospisilik)

In this episode of the Epigenetics Podcast, we caught up with Dr. Andrew Pospisilik from the Van Andel Institute in Grand Rapids, Michigan to talk about his work on the epigenetic origins of heterogeneity and disease.

Dr. Andrew Pospisilik worked at the Max-Planck Institute of Immunobiology and Epigenetics in Freiburg for 8 years and in 2018 he joined the Van Andel Institute as the director of its Center for Epigenetics. At the Van Andel Institute his research focuses on diabetes, neurodegenerative diseases, cancer, and obesity. The goal of the Pospisilik laboratory is to better understand epigenetic mechanisms of these diseases and the roles of epigenetics in disease susceptibility and heterogeneity.

These areas of medicine are among the most important public health challenges, with the latest estimates suggesting that they impact more than 1 billion people worldwide. Although these diverse conditions are all very different, they are now thought to be caused, at least partially, from alterations in the epigenetic mechanisms that regulate gene expression and metabolism. This interview covers recent work from the Pospisilik lab on the epigenetics of these complex diseases.

References

Contact

Jaksot(171)

RNA modifications and Gene Expression (Michaela Frye)

RNA modifications and Gene Expression (Michaela Frye)

In this episode of the Epigenetics Podcast, we talked with Michaela Frye from he German Cancer Research Center (DKFZ) in Heidelberg about her work on the role of RNA modifications and RNA binding prot...

26 Maalis 45min

Polycomb and Three-Dimensional Genome Organisation (Oliver Bell)

Polycomb and Three-Dimensional Genome Organisation (Oliver Bell)

In this episode of the Epigenetics Podcast, we talked with Oliver Bell from the University of Southern California in Los Angeles about his work on chromatin-based regulatory systems that encode cellul...

12 Maalis 48min

From Placeholder Nucleosomes to Zygotic Genome Activation (Patrick Murphy)

From Placeholder Nucleosomes to Zygotic Genome Activation (Patrick Murphy)

In this episode of the Epigenetics Podcast, we talked with Patrick Murphy from Cornell University about his work on gene regulation and cellular identity. Dr. Murphy's research focuses on the molecu...

26 Helmi 39min

Decoding Cell Fate Through 3D Genome Organization and Chromatin Dynamics (Srinjan Basu)

Decoding Cell Fate Through 3D Genome Organization and Chromatin Dynamics (Srinjan Basu)

In this episode of the Epigenetics Podcast, we talked with Srinjan Basu from Imperial College London to talk about his work on how chromatin architecture and epigenetic mechanisms orchestrate developm...

12 Helmi 41min

Taking ChIP from Yeast to ENCODE to Enable Genome-Wide Regulatory Protein Mapping (Peggy Farnham)

Taking ChIP from Yeast to ENCODE to Enable Genome-Wide Regulatory Protein Mapping (Peggy Farnham)

In this episode of the Epigenetics Podcast, we talked with Peggy Farnham from the Keck School of Medicine at USC about her work on establishing the ChIP Method in mammalian cells. In this episode, we ...

29 Tammi 29min

Spatial-Omics and Machine Learning in Muscle Stem Cell Repair (Will Wang)

Spatial-Omics and Machine Learning in Muscle Stem Cell Repair (Will Wang)

In this episode of the Epigenetics Podcast, we talked with Will Wang from Sanford Burnham Prebys about his work on muscle stem cell repair, regeneration, and aging, exploring spatial-omics and machine...

15 Tammi 55min

The Future of Protein–DNA Mapping (Mitch Guttman)

The Future of Protein–DNA Mapping (Mitch Guttman)

In this episode of the Epigenetics Podcast, we talked with Mitch Guttman from Caltec about ChIP-DIP (ChIP-Done In Parallel). ChIP-DIP is a newly developed approach for high-resolution protein–DNA inte...

18 Joulu 20251h 2min

Chromatin Modifiers and Their Roles in Brain Development (Fides Zenk)

Chromatin Modifiers and Their Roles in Brain Development (Fides Zenk)

In this episode of the Epigenetics Podcast, we talked with Fides Zenk from the École polytechnique fédérale de Lausanne about her work on transgenerational inheritance in Drosophila and brain organoid...

4 Joulu 202528min

Suosittua kategoriassa Tiede

tiedekulma-podcast
rss-mita-tulisi-tietaa
rss-poliisin-mieli
rss-metsantuntijat-podcast
filocast-filosofian-perusteet
rss-duodecim-lehti
mielipaivakirja
rss-astetta-parempi-elama-podcast
rss-tiedetta-vai-tarinaa
rss-luontopodi-samuel-glassar-tutkii-luonnon-ihmeita
university-of-eastern-finland
utelias-mieli
docemilia
menologeja-tutkimusmatka-vaihdevuosiin
rss-bios-podcast
rss-ranskaa-raakana
rss-ylistys-elaimille
rss-lapsuuden-rakentajat-podcast
rss-lihavuudesta-podcast
rss-sosiopodi