35. Pulmonary Embolism Masterclass with Dr. Rich Channick

35. Pulmonary Embolism Masterclass with Dr. Rich Channick

On this week's release, Cyrus and Nick revisit one of their favorite topics: Pulmonary Embolism! In this episode - a follow up to our two-parter from season 1 - we sit down with Dr. Rick Channick of UCLA to talk about his approach to PE management with a focus on catheter directed therapies & PE response teams. This episode is packed full of expert insights and practical clinical pearls. Give it a listen and let us know what you think!


Risk Stratification Methodologies


What is the landscape of risk stratification in Pulmonary Embolism (PE)?

Broadly, what interventions does each risk category group warrant?


  • Rule of Thumb: The greater the risk to the patient, the more likely aggressive interventions will be considered.
  • Most patients with PE are low risk:
  • Typically treated with systemic anticoagulation
  • Excellent prognosis
  • High risk PE patients typically have hemodynamic involvement and can present in shock requiring emergent management :
  • No contraindications + shock due to PE systemic thrombolysis
  • Absolute contraindications:
  • Prior history of ICH
  • Known cerebrovascular lesion
  • Known malignant intracranial neoplasm
  • Non-acute ischemic stroke, within the last 3 months
  • Suspect aortic dissection
  • Intermediate risk patients:
  • Management options exist and are tailored to each specific patient.
  • Most, but not all, patients with PE deemed to be at intermediate risk will do well with systemic anticoagulation.
  • Some patients are good candidates for catheter directed therapies such as thrombectomy or thrombolysis.
  • Who? We don’t really know with a high degree of certainty. Considerations should be made for those with numerous risk factors for poor PE-related outcomes OR those with significant cardiopulmonary reserve / excellent functional status who theoretically could benefit from more brisk reversal of their acute pulmonary hypertension.


See more in depth show notes at criticalcaretime.com

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72. ICU Toxicology with Dr. Adam Mora

72. ICU Toxicology with Dr. Adam Mora

On this week, Cyrus & Nick are joined again by intensivist extraordinaire, Dr. Adam Mora, for a long overdue episode on ICU Toxicology! Together, the three of us embark on a case-based journey coverin...

23 Maalis 1h 53min

71. LIVE! From CHEST 2025: Cases in Cardiogenic Shock

71. LIVE! From CHEST 2025: Cases in Cardiogenic Shock

We've been teasing this one for a while and now it's finally ready! This week we've released our first LIVE podcast from Chest 2025 where we cover cases in cardiogenic shock with our amazing panel of ...

9 Maalis 49min

70. Right Heart Failure with Dr Matt Siuba

70. Right Heart Failure with Dr Matt Siuba

Buckle up because on this week's episode of Critical Care Time we are treated to a master class on Right Heart Failure with world-class educator Dr. Matt Siuba. We are taking a deep dive on diagnosis,...

23 Helmi 1h 39min

69. Mechanical Circulatory Support Master Class with Dr. Bindu Akkanti

69. Mechanical Circulatory Support Master Class with Dr. Bindu Akkanti

Folks this right here is a JAM PACKED episode of CCT goodness for you guys to enjoy! In this show for the ages we take a deep dive into the world of Mechanical Circulatory Support (MCS) and Cardiopulm...

9 Helmi 1h 45min

68. Sleep for ICU Clinicians: Functioning Better on Night Shifts

68. Sleep for ICU Clinicians: Functioning Better on Night Shifts

On this week’s BONUS episode of Critical Care Time, Cyrus & Nick flip the coin on sleep and discuss the importance of sleep for those of us that have to work nights. We also discuss how to find ways t...

2 Helmi 1h 7min

67. Sleeping in the ICU: Why is it critical and how do we help our patients get more of it?

67. Sleeping in the ICU: Why is it critical and how do we help our patients get more of it?

On this episode of Critical Care Time we delve into the fascinating world of sleep with a focus on the importance of sleep in our ICU patients and how we can promote good quality sleep in the sickest ...

26 Tammi 1h 18min

66. Rheumatology Emergencies with Dr. Marcela Ferrada

66. Rheumatology Emergencies with Dr. Marcela Ferrada

On this episode of Critical Care Time, we tackle the enigma - shrouded in mystery and caped in uncertainty - know as rheumatologic emergencies in the critically ill patient! We sit down with Dr. Marce...

12 Tammi 1h 31min

65. Journal Club: The RSI Trial

65. Journal Club: The RSI Trial

This Critical Care Time bonus is our ode to RSI... that is the RSI Trial! In this episode, we'll unpack all the important elements of the recently released RSI Trial by the Pragmatic Critical Care Res...

29 Joulu 202529min

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