Ep 158 Scarlet Fever: You’ve changed

Ep 158 Scarlet Fever: You’ve changed

A mere 150 years ago, uttering the words “scarlet fever” was enough to strike fear into the hearts of many, especially parents of young children. For a brief period of time, this disease, caused by an infection with the bacterium Streptococcus pyogenes, reigned as a leading cause of childhood death in many parts of the world. It left its mark on gravestones, in public health decrees, in literature like the Velveteen Rabbit, but then something changed. The disease became milder, no longer the deadly threat it once was. But it didn’t go away entirely or lose its bite completely. In this episode, we examine the biology of scarlet fever and trace how it can make you sick before exploring its strange and tragic history. How did such a deadly disease change almost overnight, before any effective treatment was developed? And what can that tell us about its potential to change back? Tune in to find out.

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Ep 205 Cancer Part 4: Where do things stand today?

Ep 205 Cancer Part 4: Where do things stand today?

For the entirety of our species’ history, our approach to cancer has largely been to react, to design new therapies and better combinations of treatments. This energy has certainly been well-spent, bu...

31 Maalis 1h 19min

Ep 204 Cancer Part 3: How do we treat it?

Ep 204 Cancer Part 3: How do we treat it?

A century and a half ago, the list of effective cancer treatments was essentially a single entry: surgery. Today, in 2026, you’d need pages to contain the number of treatments available, and multiple ...

24 Maalis 1h 32min

Special Episode: Lawrence Ingrassia & A Fatal Inheritance

Special Episode: Lawrence Ingrassia & A Fatal Inheritance

For centuries, physicians noticed that cancer sometimes ran in families, but until the 1960s, an answer to this mystery remained out of reach. Only then were scientists beginning to unlock the cellula...

17 Maalis 45min

Ep 203 Cancer Part 2: Why does it happen?

Ep 203 Cancer Part 2: Why does it happen?

Each of our cells can become cancerous. It’s an uncomfortable, yet unavoidable truth. Nor is it a truth restricted to our species - cancer is a consequence of complex life. The features that make a ce...

10 Maalis 1h 18min

Ep 202 Cancer Part 1: What is it?

Ep 202 Cancer Part 1: What is it?

Cancer has touched every one of us in some capacity, and learning of a diagnosis inspires many more questions than it answers. In this four-part series on cancer, we aim to lay a foundation of knowled...

3 Maalis 1h 36min

Special Episode: Jon Adams and Edmund Ramsden & Rat City

Special Episode: Jon Adams and Edmund Ramsden & Rat City

What happens if you put a bunch of rats in an enclosure and provision them with unlimited food and water? Researcher John B. Calhoun was committed to finding out. Results from Calhoun’s “rat utopia” e...

24 Helmi 56min

Ep 201 Poop Part 2: Flushed away

Ep 201 Poop Part 2: Flushed away

Poop is an incredibly valuable and massively underutilized resource. However, most of us don’t see it that way because of our evolutionarily ingrained disgust towards poop. Flush toilets and intricate...

17 Helmi 1h 21min

Ep 200 Poop Part 1: How the sausage gets made

Ep 200 Poop Part 1: How the sausage gets made

It might be stinky and it might be unpleasant to behold, but we all do it. For many of us, our poop is out of sight, out of mind once we flush it away. But for the next hour and fifteen minutes or so,...

10 Helmi 1h 11min

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