157 | Elizabeth Strychalski on Synthetic Cells and the Rules of Biology

157 | Elizabeth Strychalski on Synthetic Cells and the Rules of Biology

Natural selection has done a pretty good job at creating a wide variety of living species, but we humans can't help but wonder whether we could do better. Using existing genomes as a starting point, biologists are getting increasingly skilled at designing organisms of our own imagination. But to do that, we need a better understanding of what different genes in our DNA actually do. Elizabeth Strychalski and collaborators recently announced the construction of a synthetic microbial organism that self-reproduces just like a normal unicellular creature. This work will help us understand the roles of genes in reproduction, one step on the road to making DNA molecules and artificial cells that will perform a variety of medical and biological tasks.

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Elizabeth Strychalski received her Ph.D. in physics from Cornell University. She is the founder and current leader of the Cellular Engineering Group at the National Institute of Standards and Technology. She serves on the steering group for the Build-A-Cell collaboration.


Jaksot(419)

348 | Jessica Riskin on Jean-Baptiste Lamarck and Life as Creative Agency

348 | Jessica Riskin on Jean-Baptiste Lamarck and Life as Creative Agency

"Lamarkism" is a term often attached to a seemingly discredited idea in evolutionary biology: that one organism could acquire characteristics (e.g., becoming stronger through exercise) that would then...

23 Maalis 1h 15min

347 | Andrew Guthrie Ferguson on How Your Data Will Be Used Against You

347 | Andrew Guthrie Ferguson on How Your Data Will Be Used Against You

In the 18th century, philosopher Jeremy Bentham suggested the Panopticon as a model of a prison where inmates could be constantly observed by just a single prison guard. Although his original idea was...

16 Maalis 1h 8min

346 | Erica Cartmill on How Human and Animal Minds Think and Play

346 | Erica Cartmill on How Human and Animal Minds Think and Play

Intelligence is a many splendored thing, especially when it comes to comparisons between species. Chimpanzees are better than humans at some numerical tasks, but less good at understanding what number...

9 Maalis 1h 28min

AMA | March 2026

AMA | March 2026

Welcome to the March 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patre...

2 Maalis 3h 53min

345 | Adam Elga on Being Rational in a Very Large Universe

345 | Adam Elga on Being Rational in a Very Large Universe

Behaving rationally involves facing up to conditions of uncertainty; we never navigate the world with perfect confidence. Sometimes we are uncertain about the way the world is, but we can also be unce...

23 Helmi 1h 34min

344 | Adam Gurri on Liberal Democracy and How to Fight For It

344 | Adam Gurri on Liberal Democracy and How to Fight For It

It's possible to look at the course of history over the past few centuries and discern a movement toward increasing democracy, freedom, and individual rights -- "liberalism," in the political-philosop...

16 Helmi 1h 21min

343 | Tom Griffiths on The Laws of Thought

343 | Tom Griffiths on The Laws of Thought

For all that human beings spend a lot of their time thinking, it's far from obvious what that process actually entails. Part of it amounts to classical logical reasoning. But an even bigger part invol...

9 Helmi 1h 19min

AMA | Feb 2026

AMA | Feb 2026

Welcome to the February 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pa...

2 Helmi 3h 10min

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