Merel Kindt: How to Eliminate Phobias and PTSD Permanently

Merel Kindt: How to Eliminate Phobias and PTSD Permanently

Merel Kindt discusses how fear extinction can be achieved permanently, covering propranolol, epigenetics, psychedelics, and the broader implications of erasing fear. The conversation explores scientific approaches to phobias, PTSD, and future challenges in fear‑removal research.- 00:00 - Introduction to fear extinction- 14:07 - Propranolol and blood/brain barrier- 18:32 - Epigenetics and inherited fears- 26:33 - Removing fear of public speaking- 30:36 - PTSD- 33:45 - Psychedelics MDMA for self‑treatment- 37:29 - Pilot study with cigarette addiction- 42:31 - Should we get rid of fear? Consequences- 43:13 - MDMA vs LSD vs Psilocybin- 48:07 - Fear of silverfish- 50:13 - Modeling‑based phobias- 54:37 - Kindt 2009 paper on memory engrams- 55:34 - Kindt 2019 paper- 58:02 - Imagery scripting- 59:35 - Disgust removal?- 1:00:36 - How beta‑blockers work- 1:02:04 - Sleep for memory reconsolidation- 1:03:33 - Startle reflex measurement- 1:06:07 - Testing alternative beta‑blocker- 1:07:12 - Future challenges and limitationsSPONSORS:- Patreon: https://patreon.com/curtjaimungal- PayPal: https://bit.ly/2EOR0M4- Twitter: https://twitter.com/TOEwithCurt- Apple Podcasts: https://podcasts.apple.com/ca/podcast/better-left-unsaid-with-curt-jaimungal/id1521758802- Pandora: https://pdora.co/33b9lfP- Spotify: https://open.spotify.com/show/4gL14b92xAErofYQA7bU4e- Google Podcasts: https://play.google.com/music/listen?u=0#/ps/Id3k7k7mfzahfx2fjqmw3vufb44RESOURCES:- DOCUMENTARY SERIES: https://www.youtube.com/watch?v=pM3G6kITdYk- MEREL'S WEBSITE: https://kindtclinics.com/en/- http://betterleftunsaidfilm.com Theories of Everything with Curt Jaimungal features long-form, technically detailed interviews with leading researchers in physics, mathematics, consciousness, and philosophy, exploring topics at the level of active research. For academics, graduate students, and anyone seeking depth beyond popular science. SPONSOR: I subscribe to The Economist for their science and tech coverage. As a TOE listener, get 35% off! No other podcast has this: https://economist.com/TOE FOLLOW: Substack | Spotify | YouTube | Twitter Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices

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Renato Renner: Quantum Mechanics Contains Its Own Contradictions

Renato Renner: Quantum Mechanics Contains Its Own Contradictions

Renato Renner (ETH Zurich) proves quantum mechanics contains logical contradictions that undermine its foundations.Quantum theory may be the most successful theory in history — and Renato Renner has p...

30 Maalis 3h 26min

Jenny Wagner: What If We've Been Wrong About Dark Matter For Decades?

Jenny Wagner: What If We've Been Wrong About Dark Matter For Decades?

Jenny Wagner examines the inverse problem: how to map dark matter without assuming what it is.What if 85% of the universe's matter isn't missing — it's just that our models were never clean enough to ...

26 Maalis 2h 38min

Curt Jaimungal: Why Write?

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Curt Jaimungal argues writing reveals something deeper than output—what LLMs expose about human purpose.Curt Jaimungal argues that in an age where LLMs can produce beautiful prose on demand, we've dis...

19 Maalis 6min

JB Manchak: Time Travel in Physics and What We Still Don't Know

JB Manchak: Time Travel in Physics and What We Still Don't Know

Curt Jaimungal examines why physicists still can't resolve whether time travel is possible or forbidden.What if you gathered every possible piece of evidence about the universe — every observation, pa...

16 Maalis 2h 17min

Curt Jaimungal: General Relativity Is NOT Deterministic (Here's the Proof)

Curt Jaimungal: General Relativity Is NOT Deterministic (Here's the Proof)

Many people think physics / reality is either guided by a probabilistic distribution or is “determined.” Actually, there’s a third, far‐more unsettling option. Curt Jaimungal explains why Einstein’s g...

12 Maalis 21min

John Donoghue: We Have Already Quantized Gravity (And It Works)

John Donoghue: We Have Already Quantized Gravity (And It Works)

Professor John Donoghue explains why quantum physics and gravity actually work perfectly together. He tackles quadratic gravity, effective field theory, and random dynamics, arguing that grand unifica...

11 Maalis 1h 6min

Nir Lahav: A Relativistic Theory of Consciousness from Spacetime

Nir Lahav: A Relativistic Theory of Consciousness from Spacetime

A physicist proposes a relativistic theory of consciousness based on spacetime geometry and information.Physicist Nir Lahav joins me to argue that the hard problem isn't hard so much as confused—a con...

5 Maalis 3h 8min

Curt Jaimungal: Why Neil deGrasse Tyson Gets "Belief" Wrong

Curt Jaimungal: Why Neil deGrasse Tyson Gets "Belief" Wrong

Curt Jaimungal argues that astrophysicists like Neil deGrasse Tyson and spiritual gurus Deepak Chopra and Thomas Campbell can’t logically claim they don’t hold beliefs. This “Theories of Everything” w...

2 Maalis 16min

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