Ep. 262 Ozempic: Exploring the Benefits and Uses - A Comprehensive Review with Dr. Tracy Gapin

Ep. 262 Ozempic: Exploring the Benefits and Uses - A Comprehensive Review with Dr. Tracy Gapin

I am honored to reconnect with Dr. Tracy Gapin today. He is a board-certified urologist and men’s health expert. The current state of metabolic health in the United States and most westernized countries has sparked a great interest in a GLP1 agonist, AKA Semaglutide Ozempic. So I wanted to talk to a clinician actively utilizing this medication. Dr. Gapin and I discuss what this drug class represents. (These are synthetic peptides.) We speak about Semaglutide, Ozempic, Wegovy, and oral Rybelsus. We get into current research, side effects, who should not take these medications, and the mechanisms of action specific to the pancreas and beta cells, reductions, gastric emptying, and the upregulation of satiety. We discuss changes in the brain regarding leptin and how these drugs work. We also talk about weight loss resistance, and I answer questions from listeners. From my perspective, it all comes back to basics. I believe that if we are to prescribe these medications, we must help our patients understand how lifestyle impacts weight-loss resistance and metabolic health. I loved that Dr. Tracy spent some time talking about the specific ways he works with his patients, even before prescribing medications. He also explains how important he has felt this drug has been for his patients. I approached today’s conversation with an open mind, and I hope you will do the same. IN THIS EPISODE YOU WILL LEARN: How the GLP1 agonists help Dr. Tracy motivate his patients to lose weight. What are GLP1 agonists, and how do they work? The physical benefits of GLP1 agonists. Who is Semaglutide not appropriate for? Some of the common side-effects of GLP1 agonists. How those who fail to implement lifestyle changes when they stop using Semaglutide may regain all the weight they lost. Why it is essential to stay hydrated when using Semaglutide. Why you need to eat enough food- protein in particular when taking Semaglutide. How to follow the metrics that matter. Some factors that could hinder successful weight loss. What Dr. Tracy does to ensure his patients do not regain the weight they lost after they stop using Semaglutide. Listener questions: Why is a diabetic drug being used for non-diabetics? Does this drug target muscle versus fat in terms of weight loss? For how long do most patients take it? Are there unique characteristics in perimenopausal and menopausal women that must be accounted for differently? Bio: Dr. Tracy Gapin is a board-certified urologist, a world-renowned men’s health & performance expert, and the founder of the Gapin Institute, the global leader in High-Performance Health. He has over 20 years of experience focused on men’s health optimization, human performance, and longevity, providing executives & entrepreneurs a personalized path to fulfill their highest potential. He’s been featured in Entrepreneur, Dave Asprey’s Biohacking Conference, and as a TEDx speaker. Connect with Cynthia Thurlow Follow on Twitter, Instagram & LinkedIn Check out Cynthia’s website Connect with Tracy Gapin On his website Gapin Institute Text “Health” to 26786 to receive 10 Secrets to High-Performance Health and a free copy of Dr. Gapin’s book.

Jaksot(623)

Ep. 537 The #1 Longevity Nutrient You’re Missing – How Fiber Supercharges Your Gut, Immunity & Sleep with Dr. Will Bulsiewicz | Gut Health , Menopause & Sleep

Ep. 537 The #1 Longevity Nutrient You’re Missing – How Fiber Supercharges Your Gut, Immunity & Sleep with Dr. Will Bulsiewicz | Gut Health , Menopause & Sleep

Today, I am thrilled to connect with Dr. Will Bulsiewicz, a board-certified gastroenterologist, gut health authority, and New York Times bestselling author with an upcoming book called Plant Powered Plus.  In our discussion today, we examine the gut-immune connection, looking at how inflammation affects the gut microbiome and gut barrier, and how technology and lifestyle impact our health. We discuss the limitations of conventional allopathic medical approaches to disease, the telltale signs that inflammation may underlie your gut-related symptoms, why fiber is the longevity nutrient, and the critical importance of short-chain fatty acids. We also explore the food matrix, changes in perimenopause and menopause regarding fiber intake, the significance of lipopolysaccharides and circadian biology, and how fiber can improve your sleep quality.  This episode is truly a must-listen. I thoroughly enjoyed connecting with Dr. B. I have admired his work for years, and his new book is one you will want to buy for its insights and your enjoyment. IN THIS EPISODE, YOU WILL LEARN: Lifestyle changes that are essential for preventing and managing chronic diseases The importance of fiber for chronic disease prevention How fiber feeds the gut microbes  Why women need more fiber during perimenopause and menopause Why you need to increase your fiber intake gradually How fermented foods support microbiome diversity and reduce inflammation How gut barrier leaks can trigger immune activation and inflammation How circadian rhythm disruptions affect the microbiome The value of consistent fiber intake for better sleep quality Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community (The Midlife Pause/Cynthia Thurlow)  Cynthia’s Menopause Gut Book is on presale now! Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause supplement line Connect with Dr. Will Bulsiewicz On his website Preorder a copy of Plant Powered Plus

3 Tammi 1h 4min

Ep. 536 “Fiber Isn’t Optional” – The Most Powerful Way Women in Menopause Lose Weight Naturally | Weight loss & Menopause

Ep. 536 “Fiber Isn’t Optional” – The Most Powerful Way Women in Menopause Lose Weight Naturally | Weight loss & Menopause

We have another episode today where I answer questions from my podcast listeners, providing more details than I usually would in the podcast. I genuinely hope you’re enjoying these short-form videos and podcasts. I’d love to know which topics you'd like me to cover in this YouTube format, where I can dive a little deeper into your questions. Please share your thoughts! IN THIS EPISODE, YOU WILL LEARN: What our ability to eat fiber reflects about the health of our microbiome How hormonal changes in midlife influence women’s weight patterns and metabolic flexibility How declining estrogen during perimenopause and menopause affects the gut microbiome How fiber can indirectly support weight loss  How fiber helps maintain gut barrier integrity and reduces systemic inflammation Why middle-aged women need more protein  The role the strobilome plays in supporting estrogen recycling and gut detoxification  Practical strategies for increasing fiber intake safely and sustainably Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow  Cynthia’s Menopause Gut Book is on presale now! Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement Line

1 Tammi 23min

Ep. 535 Masterclass: Inflammation, Hormones & Weight Loss | Hormones & Menopause

Ep. 535 Masterclass: Inflammation, Hormones & Weight Loss | Hormones & Menopause

Today, we have the second episode of a two-part mashup series focused on weight-loss resistance.  For today’s episode, I am delighted to welcome experts Dr. Mary Claire Haver, Dr. Rocio Salas-Whalen, and Physician’s Assistant McCall McPherson.  Dr. Haver and I explore how inflammation drives weight gain and unpack specific strategies for macronutrients, meal timing, and more. Dr. Salas-Whalen and I examine body composition changes during perimenopause and menopause, our family responsibilities, the importance of strength training for maintaining muscle mass, and the targeted use of GLP-1 agonist drugs. Finally, McCall and I break down the labs that help guide decision-making, also discussing informed consent, the effects of hormonal replenishment therapy (now known as personalized endocrine treatment), the strategic use of GLP-1s, personalized dosages, and microdosing. This mashup includes many timely and relevant insights from three experts at the forefront of women’s health. Join us as we explore the science, strategies, and solutions shaping the future of weight loss resistance. IN THIS EPISODE, YOU WILL LEARN: How slowing sugar absorption reduces insulin spikes and inflammation The value of combining healthy fats, complex carbs, and lean protein at every meal  Why spreading protein intake throughout the day is crucial for metabolism, hormone regulation, and muscle preservation How prioritizing self-care and modeling it for children helps break the cycle of parental over-sacrifice Why strength training is more effective than cardio for long-term body composition and metabolic health The mounting stress, family pressures, and reduced self-care that many women face in their 40s and 50s How synthetic hormones in oral contraceptives disrupt thyroid, testosterone, and reproductive hormones How GLP-1 agonists can improve weight loss, food freedom, and metabolic flexibility How supporting adrenal health enhances energy, balances hormones, and improves metabolic flexibility Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community (The Midlife Pause/Cynthia Thurlow)  Cynthia’s Menopause Gut Book is on presale now! Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause supplement line Connect with Dr. Mary Claire Haver On her website Instagram and TikTok The Galveston Diet Book Ep. 308 Weight Gain in Middle Age, Perimenopause and Inflammation with Mary Claire Haver Connect with Dr. Rocio Salas-Whalen On her website Instagram Ep. 384 Why Weight Loss is Complex: Obesity’s Multi-Factorial Nature with Dr. Rocio Salas-Whalen Connect with McCall McPherson Modern Thyroid Clinic On Instagram and TikTok Modern Thyroid and Wellness Podcast Thyroid Lab Guide Ep. 282 Thyroid Health: Hormones, Medications & Weight Loss with McCall McPherson

31 Joulu 20251h 5min

BONUS: Bio-individuality and Fasting: Personalized Approaches to Metabolic Health with Dr. Jason Fung

BONUS: Bio-individuality and Fasting: Personalized Approaches to Metabolic Health with Dr. Jason Fung

I am delighted to reconnect with Dr. Jason Fung today. We last connected in October 2020 for Episode 121.  Dr. Fung is a nephrologist and a prominent figure in the intermittent fasting and low-carb space. He has made significant contributions as a founding member of The Fasting Method, providing evidence-based guidance on weight loss and blood glucose management through low-carb diets and intermittent fasting. He has written several books, including The Obesity Code, The Complete Guide to Fasting, The Diabetes Code, and The Cancer Code.  In our discussion today, we look at the forecast for metabolic health in 2024, exploring how the growth of the diabetes population relates to the effects of the pandemic and addressing the conflict of interest with organizations like the ADA and registered dieticians. Dr. Fung shares some of his biggest frustrations, including the shallow and myopic thinking amongst those focusing on calories in and calories out, and we get into various facets of metabolic health, from the nuanced influences of gender, puberty, perimenopause, and menopause to hedonistic eating, sarcopenia, bio-individuality, and therapeutic fasting. Dr. Fung also shares his perspective on GLP-1s, shiftwork, supplements, and more. Join us for valuable insights on various aspects of metabolic health and how they impact our well-being. IN THIS EPISODE YOU WILL LEARN How the influence of food companies has led dieticians and diabetes associations to focus on moderation instead of a balanced diet Dr. Fung shares his frustration with the lack of progress in addressing the diabetes issue How hormones impact weight gain and hunger Why does focusing on calories in and out not provide the solution to weight loss? How intermittent fasting can help to control hormonal issues How middle-aged women need to find balance when fasting to maintain muscle mass and avoid sarcopenia How intermittent fasting can lead to increased strength despite losing muscle mass  What causes shift workers to gain weight? The potential drawbacks of using GLP-1 drugs for weight loss Why magnesium deficiency is a common problem in modern society Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community (The Midlife Pause/Cynthia Thurlow)  Cynthia’s Menopause Gut Book is on presale now! Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause supplement line Connect with Dr. Jason Fung ⁠Website⁠ ⁠Twitter ⁠and ⁠YouTube⁠ ⁠The Fasting Method⁠ Dr. Fung's ⁠books⁠ Previous Episode Featuring Dr. Jason Fung ⁠Ep. 121 – The Truth About Diabetes, Kidney Disease and Insulin Resistance with Dr. Jason Fung⁠

29 Joulu 202556min

Ep. 534 The Hidden Forces Making Women Gain Weight – The Shocking Truth About Hormones, Trauma & GLP-1s | Hormones & Menopause with Dr. Rocio Salas-Whalen

Ep. 534 The Hidden Forces Making Women Gain Weight – The Shocking Truth About Hormones, Trauma & GLP-1s | Hormones & Menopause with Dr. Rocio Salas-Whalen

Today, I’m thrilled to reconnect with Dr. Rocio Salas-Whalen, a board-certified endocrinologist and obesity medicine specialist with more than 15 years of clinical experience, widely recognized as one of the earliest adopters of GLP-1 therapies in the United States. She is also the author of the upcoming book Weightless: A Comprehensive Guide to the New Era of GLP-1 Medications. In our discussion, we explore the transgenerational impact of obesity as a complex, chronic, and deeply multifactorial condition. We discuss the effects of environmental exposures and trauma, the essential role of education in overcoming weight-loss resistance and managing obesity, and the physiological changes women experience in the perimenopause-to-menopause transition. We explain the importance of body positivity and image, reframing our thoughts around obesity and being overweight, and why building and maintaining muscle is non-negotiable. We dive into the physiology of GLP-1 medications and specific targets for women in perimenopause and menopause, ways to address weight-loss stalls, and the effects of the weight bias so deeply entrenched in our society. Dr. Salas Whalen also shares her thoughts on alternatives and additions to GLP-1 therapies, clarifying the importance of protein and strength training while using GLP-1 drugs.  This conversation with Dr. Salas-Whalen is truly invaluable, and I highly recommend her upcoming book, Weightless. IN THIS EPISODE, YOU WILL LEARN: • What people come to understand about “normal eating” after starting GLP-1s • How GLP-1s interrupt the binge–guilt–shame cycle • The role GLP-1s play in helping people stay in control of food rather than letting food control them • Strategies for avoiding side effects when using GLP-1 medications • Why certain foods trigger problems on injection days • Importance of proper guidance to prevent severe side effects • The impact a prescriber’s guidance has on your success with GLP-1s • Why treatment plans must be tailored to each patient’s needs and metabolism • Factors doctors consider when deciding whether to add additional medications to a GLP-1 plan Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community (The Midlife Pause/Cynthia Thurlow)  Cynthia’s Menopause Gut Book is on presale now! Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause supplement line Connect with Dr. Rocio Salas-Whalen Website On social media: @drsalaswhalen Dr. Rocio’s Book, Weightless - Pre-order now! (Releases 12-30-25)

27 Joulu 202557min

Ep. 533  “Under 60 or Else?” – The Dangerous Myth Limiting Women’s Hormone Therapy

Ep. 533 “Under 60 or Else?” – The Dangerous Myth Limiting Women’s Hormone Therapy

We have another AMA episode today, where I answer some of the most frequently asked podcast listener questions. In response to a question from Catherine, we unpack the timing hypothesis in this episode, exploring the cardiovascular nuances and clarifying why individualized care truly matters. IN THIS EPISODE, YOU WILL LEARN: Cardiovascular and metabolic benefits of starting hormone therapy within about 10 years of menopause onset What the timing hypothesis really means in clinical practice Why feeling better does not necessarily imply long-term disease risk has been reduced How endothelial (blood vessel) health influences the effectiveness of hormone therapy  Why metabolic changes after menopause matter more than most women realize How their hormone therapy decisions must change as women move further beyond menopause  Risks and benefits of oral versus transdermal hormone delivery Value of shared patient-clinician decision-making  How lifestyle habits and risk assessment form the foundation for safe, effective, and personalized hormone therapy decisions Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow  Cynthia’s Menopause Gut Book is on presale now! Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement Line

25 Joulu 202517min

Ep. 532 Medicine Has Lost Its Way – The Most Honest Take on What’s Broken | Menopause with Drs. Lazris & Roth

Ep. 532 Medicine Has Lost Its Way – The Most Honest Take on What’s Broken | Menopause with Drs. Lazris & Roth

Today, I am honored to connect with doctors Andy Lazris and Alan Roth, the authors of A Return to Healing. Dr. Lazris, a physician practicing geriatric primary care medicine in Maryland, is a Certified Medical Director who orchestrates medical care and provides education for several long-term care facilities. Dr Roth is a physician, practicing family medicine and palliative care in New York. He is the Chairman of the Department of Family Medicine and Ambulatory Care at MediSys Health Network.  In our discussion, we explore the impact of the Flexner Report, including how it has reshaped our medical system and clinical guidelines, expanded the definition of disease, and influenced critical thinking. Drs. Lazris and Roth explain how challenging established medical dogma becomes even more problematic within a Flexnerian framework. They examine the prevalence of ineffective and costly procedures, the manipulation of research studies, the role of documentation in medical literature, and the impact of terms like non-compliant and histrionic on the quality of patient care. They also clarify what actually happens with screening measures and how patients can find excellent care.  Their book, A Return to Healing, is truly a love letter to their communities. It is a must-read for anyone seeking to understand the complexities of our current medical system and how it has gotten derailed. IN THIS EPISODE, YOU WILL LEARN: Why doctors should question dogma and think critically rather than just following medical guidelines How medical training encourages standardized testing and discourages nuanced and patient-centered thinking How our profit-driven system rewards procedures and prescriptions over proper patient care Why drugs can sometimes cause more harm than good, and how elderly patients often suffer due to overprescribing How drug companies manipulate statistics to make small benefits seem huge Why patient noncompliance can often mean informed refusal rather than ignorance or defiance How biased medical documentation may unfairly target women and minorities Modern fast-food-type medicine and eroding trust within the doctor–patient relationship Why shared decision-making is meaningless in a system built on one-size-fits-all dogma Protecting yourself within a dysfunctional medical system Connect with Cynthia Thurlow  Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community (The Midlife Pause/Cynthia Thurlow)  Cynthia’s Menopause Gut Book is on presale now! Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause supplement line Connect with Dr. Andy Lazris and Dr. Alan Roth On their⁠ website⁠ Email Dr. Lazris: ⁠alazris50@gmail.com ⁠ Email Dr. Roth: ⁠aroth@jhmc.org ⁠

24 Joulu 202558min

BONUS: AMA: What Every Woman Needs to Know About Their Health with Dr. Tabatha Barber

BONUS: AMA: What Every Woman Needs to Know About Their Health with Dr. Tabatha Barber

I am delighted to have my good friend and fan-favorite, Dr. Tabatha Barber, join me again to share her wisdom on the podcast!  Dr. Tabatha is a triple board-certified OB/GYN specializing in menopause and functional medicine. She has a wonderful podcast called The Gutsy Gynecologist Show and is often referred to affectionately as the Gutsy Gynecologist. Dr. Tabatha was with me in two previous podcast episodes, ⁠#206⁠ and ⁠#212⁠, and both are in the top twenty downloaded podcasts in the last 18 months! Many women suffer unnecessarily when going through perimenopause and menopause. Dr. Tabatha and I have an AMA (Ask Me Anything) episode today. We discuss weight gain related to perimenopause and menopause, issues with estrogen replacement therapy, how many different factors can impact libido, how to address a partial hysterectomy and HRT, and bioidenticals versus synthetic hormones. We also get into lab work, skin reactions relative to perimenopause and menopause, emotional eating, leptin resistance, and many other topics.  I’m grateful for all the great questions and have no doubt this episode with Dr. Tabatha will be another fan-favorite! IN THIS EPISODE YOU WILL LEARN: Why do too much estrogen and too little estrogen both cause weight gain?  How fragrances and plastic contribute to the imbalance between estrogen and progesterone. How changing to organic tampons and pads, or using a Diva cup, can be a game-changer for women. Should women who have had a partial hysterectomy and are on HRT still check progesterone and testosterone levels and fast like a post-menopausal female? Dr. Tabatha shares her thoughts on plain estradiol versus Biest and Triest. Dr. Tabatha offers her recommendations for a healthy 48-year-old female with zero libido. What can a 17-year-old with high testosterone do to get her testosterone level within the normal range? Is there a biological or mindset issue at play if you never feel full and always want to eat, irrespective of how healthy or satisfying the foods you eat are? The benefits of fasting.  What can we do to support our pelvic joints? How do our hormones affect our skin? Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community (The Midlife Pause/Cynthia Thurlow)  Cynthia’s Menopause Gut Book is on presale now! Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause supplement line Connect with Dr. Tabatha Barber On her ⁠website⁠ ⁠The Gutsy Gynecologist Show⁠ ⁠Episode 206 Pt 1: A Deep Dive into Perimenopause- Hormonal Imbalances and Birth Control with Dr. Tabatha Barber⁠ ⁠Episode 212 Pt. 2: A Deep Dive into Hormonal Imbalances and Menopause with Dr. Tabatha Barber⁠ Books mentioned: ⁠The XX Brain⁠ by Lisa Mosconi

22 Joulu 20251h 4min

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