S6 - E5.3 - Expert: Scott Friedman on Gene Therapy and Advances in Liver Science

S6 - E5.3 - Expert: Scott Friedman on Gene Therapy and Advances in Liver Science

Send us a text This week’s expert, Hepatologist and Key Opinion Leader Scott Friedman, joins Roger to discuss advances in acceptance of gene therapy and knowledge in other areas of basic liver science. When discussing science, he pays particular attention to findings on the diversity of stellate cells and his interest in CAR-T as a therapy for liver disease. This conversation starts with Scott discussing gene therapy. Specifically, he applauds the idea that gene therapy is becoming acce...

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6,13 - Locating MASH patients, Population Screening for Advanced Disease, Impact of Washington on Americans' Health

6,13 - Locating MASH patients, Population Screening for Advanced Disease, Impact of Washington on Americans' Health

Send us a text 00:00:00 - Surf's Up: Season 6 Episode 13 Louise Campbell, Jörn Schattenberg and Roger Green continue their discussion of some major issues from earlier this year, while co-authors Aleksander Krag and Stine Johanset join Roger to discuss their recent publication in The Lancet, titled "Screening for Advanced Liver Disease." 00:04:45 - Major Issues of the First Six Months: Integrated Patient Management Louise drives this conversation based on two related issues she se...

5 Syys 1h 13min

S6.12.3 - After the Semaglutide Approval: What Next For MASH Therapy?

S6.12.3 - After the Semaglutide Approval: What Next For MASH Therapy?

Send us a text Key Opinion Leaders Manal Abdelmalek, Naim Alkhouri, Scott Isaacs and Zobair Younossi join Roger Green to discuss the FDA's approval of semaglutide for patients with non-cirrhotic MASH. This conversation centers on the roles that new technologies and an expanded APP population will play in MASLD and MASH management in the US, and concludes by exploring how care might look different 12 months from now, and then in subsequent years. As panelists identify some of the changes...

2 Syys 21min

S6.12.2 - After the Semaglutide Approval: Expanding MASH Awareness Will Change Medical Practices

S6.12.2 - After the Semaglutide Approval: Expanding MASH Awareness Will Change Medical Practices

Send us a text Key Opinion Leaders Manal Abdelmalek, Naim Alkhouri, Scott Isaacs and Zobair Younossi join Roger Green to discuss the FDA's approval of semaglutide for patients with non-cirrhotic MASH. This conversation focuses on how the US healthcare system must adapt to handle the growing number of MASH and MASLD patients who might seek treatment, given likely increases in publicity and education. The conversation starts with a focus on the implications of semaglutide approval for hepatolog...

31 Elo 22min

S6.12.1 - After the Semaglutide Approval: Impact on Patients and Pharmacotherapy

S6.12.1 - After the Semaglutide Approval: Impact on Patients and Pharmacotherapy

Send us a text Key Opinion Leaders Manal Abdelmalek, Naim Alkhouri, Scott Isaacs and Zobair Younossi join Roger Green to discuss FDA's approval of semaglutide for patients with non-cirrhotic MASH. This conversation focuses on benefits for patients and ways that having two drugs with different modes of action will change pharmacotherapy choices. This conversation starts with the group describing the sense of "enthusiasm" and "fulfillment" hepatology drug developers feel to see two drugs ...

31 Elo 24min

6.12 - A Second US Drug Approval! What Semaglutide's Success Portends For MASLD Care in the US

6.12 - A Second US Drug Approval! What Semaglutide's Success Portends For MASLD Care in the US

Send us a text 00:00:00 - Surf's Up, Season 6, Episode 12 This week's episode is a special three-part roundtable on the implications of the FDA's recent approval of semaglutide. Naim Alkhouri, Manal Abdelmalek, Scott Isaacs and Zobair Younossi join Roger Green in a discussion that focuses less on specifics of pharmacotherapy and more on how having two drugs available will change MASH management in the US. 00:08:45 - Part I: How Will The Semaglutide Approval Affect Patient Treatment and Pharma...

29 Elo 1h 4min

6.11.3 - Expert: Emily Andaya Asks Why There Is No "L" In the (Multi-Meatbolic) CKM Initiative

6.11.3 - Expert: Emily Andaya Asks Why There Is No "L" In the (Multi-Meatbolic) CKM Initiative

Send us a text This week's expert interview is with Dr. Emily Andaya, Medical Director of the Cardiovascular Program at Major Health Partners of Shelbyville, IN. She joins Louise Campbell and Roger Green to discuss the American Heart Assocation's CKM initiative, why she believe it should be titled "CKLM" for liver, and how including liver in the CKM scoring system would make it stronger and provide a more robust tool to help improve patients' health. Emily begins by discussing her atten...

17 Elo 41min

6.11.2 - Multi-Metabolic Week Part II: Benefits of the Multi-Metabolic Approach

6.11.2 - Multi-Metabolic Week Part II: Benefits of the Multi-Metabolic Approach

Send us a text Multi-Metabolic Week focuses on the idea that MASLD and MASH are elements in a systemic set of Multi-Metabolic issues. This conversation is the second of two looking at the concept of the "Multi-Metabolic Clinic," a clinic that treats the entire spectrum of multi-metabolic diseases. This conversation starts by focusing on how the two clinics train other physicians and practices on multi-metabolic issues. The EDOM clinic in Spain is certified to provide nutritional training to o...

17 Elo 43min

6.11.1 - Multi-Metabolic Week Part I: Role of MASLD In Multi-Metabolic Clinics

6.11.1 - Multi-Metabolic Week Part I: Role of MASLD In Multi-Metabolic Clinics

Send us a text Multi-Metabolic Week focuses on the idea that MASLD and MASH are elements in a systemic set of Multi-Metabolic issues. This conversation is the first of two looking at the concept of the "Multi-Metabolic Clinic," a clinic that treats the entire spectrum of multi-metabolic diseases. The core of this episode starts during the weekly groundbreaker exercise, during which our guests began to describe the path that brought them from single-disease specialization to the broader ...

16 Elo 37min

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