Debut Biotech’s Joshua Britton on the breakthrough beetle pigment set to disrupt beauty, plus Amazon Prime sale news

The female cochineal beetle may not be aware of it, but it owes a debt of gratitude to Joshua Britton. In February, Britton’s Debut Biotech unveiled a breakthrough set to disrupt how beauty products are formulated. Using biotechnology, the San Diego-based company created a vegan, bio-identical alternative to a common red cosmetics colorant traditionally harvested from the cochineal beetle. This beetle pigment can be found on ingredient labels as “carmine,” “cochineal extract,” “crimson lake,” “natural red 4” or “C.I. 75470.” A quick online search reveals carmine in products from Stila, Fenty Beauty, Maybelline, M.A.C., Chanel and dozens more brands. Britton has had a team of 10 researchers working on this for around four years. Debut has invested around $10 million in the project thus far, and the new, vegan pigment will soon be available for the industry at scale. Britton has a PHD in biochemistry and organic chemistry and launched Debut six years ago. Debut is backed by L’Oréal’s science-focused incubator arm Bold and was named a Time 100 2025 Most Influential Companies of the Year. The company also launched its first in-house skin-care brand, called Deinde, in 2024. Glossy awarded Britton a Glossy 50 award last year. Britton joins the Glossy Beauty Podcast to discuss the breakthrough and its impact, and provides a primer on the power of biotechnology in beauty today. But first, Lexy Lebsack is joined by senior reporter Emily Jensen to discuss the news of the week. This includes early results from Amazon Prime Days, which is on track to be the retailer’s largest annual sale yet. Jensen and Lebsack also discuss Sephora’s newest brand, Beauty of Joseon, which is known for its viral and hard-to-get sunscreens. Founder Sumin Lee joined the Glossy Beauty Podcast late last year to discuss its stunning growth in the U.S. market. The company hopes to sell $120 million in the U.S. market this year.