How OxyContin Was Sold to the Masses

How OxyContin Was Sold to the Masses

When OxyContin came on the market, in 1995, physicians were understandably wary of the addictive potential of a powerful new opioid. As Patrick Radden Keefe reports, the manufacturer, Purdue Pharma, aggressively marketed OxyContin to physicians, claiming that the drug’s delayed-release mechanism could limit the risk of addiction. Instead, OxyContin led to many new addictions, and many addicted patients eventually sought street drugs like heroin. Steven May started at Purdue Pharma as a sales rep in 1999, and years later went on to allege fraud against Purdue as a participant in a whistle-blower lawsuit (which was dismissed on procedural grounds). May tells Keefe that he was trained to market the drug as one “to start with and to stay with,” despite seeing early on its addictive potential.

Purdue Pharma is a privately held company controlled by members of the Sackler family, who have a net worth of thirteen billion dollars. The Sacklers have donated handsomely to cancer research, medical schools, art museums, and universities. But Keefe tells David Remnick that the Sacklers have donated “nothing for the opioid crisis. Nothing for addiction treatment. If there is any sense in that family that they bear any moral culpability for where we are today, they’re not acting on it.”

Jaksot(1019)

Sam Altman’s Trust Issues at OpenAI

Sam Altman’s Trust Issues at OpenAI

At the end of February, OpenAI’s C.E.O., Sam Altman, made headlines by swiftly cutting a deal with the Pentagon for his company to replace Anthropic, which had balked at the Trump Administration’s bid...

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Pick Three: Spring Sports News

Pick Three: Spring Sports News

The New Yorker staff writer Louisa Thomas, who writes the Sporting Scene column, talks with David Remnick about the biggest basketball stories this season: how LeBron James embraced a new late-career ...

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How Donald Trump’s War on Iran Helps Vladimir Putin’s War on Ukraine

How Donald Trump’s War on Iran Helps Vladimir Putin’s War on Ukraine

In 2021, when Olga Rudenko and other journalists launched the English-language news outlet the Kyiv Independent, they were committed to making a publication that wouldn’t face political pressure from ...

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A Former Federal Prosecutor on Why He Quit Donald Trump’s Department of Justice

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Thousands of federal prosecutors have been fired or have resigned from their roles since Pam Bondi took over as Attorney General. She has made no secret of weaponizing the Justice Department to pursue...

31 Maalis 22min

John Lithgow on the Controversial Authors Roald Dahl and J. K. Rowling

John Lithgow on the Controversial Authors Roald Dahl and J. K. Rowling

The new play “Giant,” on Broadway, dramatizes the scandal around Roald Dahl, the beloved children’s-book author who, in the nineteen-eighties, began making antisemitic statements and invoking stereoty...

27 Maalis 28min

Julio Torres Makes Everything Funny—Including Color Theory

Julio Torres Makes Everything Funny—Including Color Theory

Julio Torres got his big break as a writer on “Saturday Night Live,” and went on to make the cult favorites “Los Espookys” and “Fantasmas” for HBO. He also wrote and directed the film “Problemista,” a...

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Is Cuba Trump’s Next Target?

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The staff writer Jon Lee Anderson has reported from Cuba for many years, and recently wrote about the deteriorating economic conditions on the island. His newest piece for the magazine dives into the ...

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Chloé Zhao on “Hamnet,” Which Is Nominated for Eight Academy Awards

Chloé Zhao on “Hamnet,” Which Is Nominated for Eight Academy Awards

Chloé Zhao became only the second woman to win an Oscar for Best Director, for 2020’s “Nomadland,” and she is nominated once again for “Hamnet,” starring Paul Mescal and Jessie Buckley. Based on Maggi...

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