Correlation vs. Causation: Part 1, a problematic clinical trial

Correlation vs. Causation: Part 1, a problematic clinical trial

Understanding correlation versus causation is important. It is important in clinical drug trials and it is important in making public policy. If we dont really understand what the underlying cause of a problem is, we cannot fix that problem. In this 2-part episode, we'll explore this concept a bit and use relevant examples to highlight what is correlated and what is truly cause-and-effect.

Episoder(15)

Vitamania, Part 2

Vitamania, Part 2

In this second part of the 2-part episode "Vitamania," we dig in to the clinical trial data behind vitamins as dietary supplements. In Part 1 of this episode, we met a patient with Scurvy....and said ...

12 Mai 202222min

Vitamania, Part 1

Vitamania, Part 1

Vitamins are widely used in the U.S., to the tune of between $15-20 billion dollars per year. But what are vitamins and what do they do? How are they regulated by the FDA and does the clinical trial d...

10 Mai 202216min

Drugs (Sometimes) Work: "Do ACE inhibitors treat Diabetes?"

Drugs (Sometimes) Work: "Do ACE inhibitors treat Diabetes?"

Before we ask a patient to take any drug we should be confident that the benefits outweigh the risks. This involves considerations like duration of therapy and whether the drug is being used to treat ...

2 Jun 202117min

Medicating the Failing Heart, Part 3 of 3: The finale

Medicating the Failing Heart, Part 3 of 3: The finale

As we finish up we focus on the contemporary management of systolic heart failure or so called heart failure with reduced ejection fraction. Our focus in this episode is on RAAS blockade which include...

18 Mai 202122min

Medicating the Failing Heart; Part 2: The difference between a drug and not a drug is dose

Medicating the Failing Heart; Part 2: The difference between a drug and not a drug is dose

In this continuation of "Medicating the Failing Heart" we pick up the theme of systolic heart failure and how good beta blockers are or aren't compared to our newest agent for systolic heart failure -...

12 Mai 202116min

Episode 9, Medicating the failing heart, Part 1

Episode 9, Medicating the failing heart, Part 1

When it comes to treating symptomatic heart failure, many things have changed but many have not. Some things that haven't changed maybe should change - that depends on who you listen to. In this multi...

7 Mai 202114min

"Ceph-a-Something" Part 2: pesky PK

"Ceph-a-Something" Part 2: pesky PK

The cephalosporin antibiotics are a confusing class of medications. We talk about them in "generations" like a pharmacologic family tree. And while there is a general rule regarding which bugs are cov...

23 Apr 202114min

"Ceph-a-Something" Part 1: Genealogy

"Ceph-a-Something" Part 1: Genealogy

The cephalosporin antibiotics are a confusing class of medications. We talk about them in "generations" like a pharmacologic family tree. And while there is a general rule regarding which bugs are cov...

23 Apr 202111min

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