America Isn’t Ready for the Weight-Loss-Drug Revolution That’s Coming

America Isn’t Ready for the Weight-Loss-Drug Revolution That’s Coming

We have historically thought about weight as the mere outcome of our deliberate choices about diet and exercise. We have not typically thought about weight like a disease. But in the past 18 months, there’s been an extraordinary revolution in weight-loss medication that's putting in our hands a therapy that can help people easily shed weight without major side effects. You may have heard these drugs go by the name Wegovy or Ozempic. What happens when you take a country obsessed with self-image and diet and tell them that the mystery of weight loss has now been reduced to a daily injection? You change a lot more than body mass index. You change society. Today’s guest is Susan Z. Yanovski. She is the co-director of the Office of Obesity Research and the program director of the Division of Digestive Diseases and Nutrition at NIH. We talk about the stakes of anti-obesity medication, why diet and exercise doesn’t work for so many people, how these weight-loss drugs could help American health care, strain American insurance, and revolutionize America’s sense of willpower, responsibility, and diet. Host: Derek Thompson Guest: Susan Z. Yanovski Producer: Devon Manze Learn more about your ad choices. Visit podcastchoices.com/adchoices

Episoder(370)

The Triple Crisis That’s Breaking Hollywood—and Changing the Future of Movies

The Triple Crisis That’s Breaking Hollywood—and Changing the Future of Movies

Hollywood is in the middle of a triple crisis. You can measure it in tickets, jobs, and ideas. Start with tickets. The best year for the movie business this century was 2002, when Americans and Canad...

24 Apr 1h 10min

The Most Powerful and Dangerous AI Model Yet

The Most Powerful and Dangerous AI Model Yet

Two weeks ago, Anthropic announced an AI model so capable and so dangerous that it decided not to release it to the public. The model, codenamed Mythos, could autonomously infiltrate computer systems...

21 Apr 1h 2min

The Whole World Is Fighting About Energy

The Whole World Is Fighting About Energy

The two biggest stories in the world right now—the war involving Iran and the rise of artificial intelligence—are, at their core, the same story: energy. The Iran conflict has become a war of competin...

14 Apr 1h 4min

‘The Job Market for Young People Is Brutal’

‘The Job Market for Young People Is Brutal’

Something weird is going on with the elevated unemployment rate for young people today, but no one knows what exactly it is. For the last year, as the unemployment rate for recent college graduates h...

10 Apr 1h 7min

America's Religious Revival Is a Mirage

America's Religious Revival Is a Mirage

Perhaps you’ve heard the news: The U.S. is experiencing a religious revival, and it’s concentrated among young people, who are flocking back to the fold. The Economist announced that “the West has sto...

8 Apr 1h 8min

Is China the Winner of the Iran War?

Is China the Winner of the Iran War?

The 1970s oil crisis changed the world in ways that many people forget today, from the transformation of American politics to the rise of the Japanese electronics industry. The Iran war of 2026 could ...

3 Apr 52min

Why We're Addicted to ‘Sh*tty Flow’

Why We're Addicted to ‘Sh*tty Flow’

One of the themes we’ve circled in the last few weeks is the way that the modern world can hijack our values. This principle was recently articulated by the philosopher C. Thi Nguyen in an episode cal...

31 Mar 48min

Anthropic Thinks AI Might Destroy the Economy. It's Building It Anyway.

Anthropic Thinks AI Might Destroy the Economy. It's Building It Anyway.

Today’s podcast is an interview with one of the cofounders of the AI company Anthropic, Jack Clark. One thing I’m trying to do with the subject of artificial intelligence is offer a balance of perspec...

27 Mar 1h 2min

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