S1 E3: Cancer polyp project
Gut Questions?22 Jun 2021

S1 E3: Cancer polyp project

In this episode I finally understand, and you can see it in my facial expressions, the cancer polyp project (human samples) and why it is so exciting for DePaolo Lab. While many groups are studying the cancer, DePaolo Lab is studying the environment where the cancer is present. Give it a listen, or watch on our YouTube channel, and meet Bacteroides fragilis, learn how bacteria are like Uber drivers and their passengers, and what happens when our “good” bacteria (commensals / probiotics) are dropped into a zombie apocalypse.

* * Shameless plea for research support * * Part of what makes this project so exciting is that the data goes against microbiome research dogma and Will hates, HATES, science dogma as you will learn in this episode. But, as he says, going against dogma doesn’t get you funded, or published, and he needs to secure funding to continue this study. If you're interested in learning more about this project and possibly supporting this research, please reach out to me, Parker, at aparker@medicine.washington.edu

If you've gut a question(s) you want Will to answer in an upcoming podcast, shoot me an email at aparker@medicine.washington.edu

A bunch of our websites and social media platforms:

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Gut Questions? website www.yourgutquestions.com
Gut Questions? Instagram www.instagram.com/gutquestions/

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DePaolo Lab website: www.depaololab.com
DePaolo Lab Instagram: www.instagram.com/depaololab/
DePaolo Lab Twitter: www.twitter.com/depaololab

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CMiST, Center for Microbiome Sciences & Therapeutics: www.cmistuw.org

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Will's LinkedIn: www.linkedin.com/in/williamdepaolo/

#microbiome
#gutmicrobiome
#guthealth
#probiotics
#sciencepodcast

Episoder(12)

S1 E6: Brief wrap of season 1 and season 2 preview

S1 E6: Brief wrap of season 1 and season 2 preview

In the second season of Gut Questions? Will and I get into the research and business of -biotics. Will is going to cover probiotics, prebioitics, synbiotics, and postbiotics. He'll give a brief over...

29 Jul 20213min

S1 E5, PUFAs and infection, Part 4: Relevance to human health

S1 E5, PUFAs and infection, Part 4: Relevance to human health

Episode 5, part 4 – Will talks about why the results from this study are relevant to our everyday lives. DePaolo Lab ultimately found that the presence of omega-6 polysaturated fatty acids (arachidoni...

27 Jul 202114min

S1 E5, PUFAs and infection, Part 3: Details of omega-6 fatty acid (arachidonic acid)

S1 E5, PUFAs and infection, Part 3: Details of omega-6 fatty acid (arachidonic acid)

In the this part of the PUFA episode, Will explains the growth and virulence changes of Yersinia enterocolitica under room and body temperatures. In essence, omega-6 fatty acids (arachidonic acid was...

27 Jul 202113min

S1 E5, PUFAs and infection, Part 2: The project design

S1 E5, PUFAs and infection, Part 2: The project design

Episode 5, part 2 - Will sets up the infection project (which was very enlightening for me). In part two of the PUFA episode, Will gives some fascinating detail on the bacteria of choice for this ...

27 Jul 202110min

S1 E5, PUFAs and infection, Part 1: Omega-6 and Omega-3 fatty acids

S1 E5, PUFAs and infection, Part 1: Omega-6 and Omega-3 fatty acids

Episode 5, part 1 - Will lays the groundwork for talking about the PUFAs and infection project. In the first part of this episode, Will introduces the two types of polyunsaturated fatty acids (PUFAs) ...

27 Jul 202118min

S1 E4, Part 2: Nonalcoholic fatty liver disease (NAFLD) - discussion

S1 E4, Part 2: Nonalcoholic fatty liver disease (NAFLD) - discussion

In the second part of this episode, Will and I talk about a bunch of stuff: • How nonalcoholic fatty liver disease (NAFLD) is reported on / presented in the news and social media • Why there is such a...

29 Jun 202129min

S1 E4, P1: Nonalcoholic fatty liver disease (NAFLD) - project

S1 E4, P1: Nonalcoholic fatty liver disease (NAFLD) - project

In the first part of this episode, Will talks about investigating nonalcoholic fatty disease (NAFLD) with Tania Mitsinikos, MD, who at the time, was a clinical fellow with Children’s Hospital Los Ange...

28 Jun 202125min

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