Dr Bill Lawrence: Reversing Aging PART 2 Bioregulator Peptides Effect on DNA Methylation Clinical Trial

Dr Bill Lawrence: Reversing Aging PART 2 Bioregulator Peptides Effect on DNA Methylation Clinical Trial

In this week’s episode, (part 2 to Episode #42)...

Nathalie continues her conversation with Dr. Lawrence about Russian Bioregulator peptides and the role they may play in reversing biological age in humans. They review several different studies, discuss organ regeneration as well as how precisely designed BioRegulator Peptide cycles have so far affected DNA methylation patterns in Clinical Trial participants.

Meet This Week's Guest

Dr. Lawrence has a Jurisprudence Degree (UCLA-Law), an MS in Psychology and a Ph.D. in Nutrition with a particular interest in Longevity. Since 1990 his focus has been on slowing and reversing human biological aging. 3 years ago he started a human clinical trial in collaboration with Dr Vladimir Khavinson from the Saint Petersburg Institute of He has developed numerous science-based protocols focused on optimal aging for health professionals and individual clients.

Presently Dr. Lawrence is the administrator of two clinical studies to determine if human biological age can be reversed. NB- Dr. Lawrence’s chronological age is 74. His ‘biological age,’ based on his telomere length is 35.

To buy the Nature's Marvels Bioregulator Peptides that Dr Lawrence uses in his trial you can click here or go to Profound-Health.com and use discount code Longevity15 to save 15% off your first order

Key Takeaways

If possible, it is best to watch this podcast on YouTube as well so that you can see the slides. There is a slide for all the highlights.

[1:04] About Dr. Lawrence and a brief overview of what was talked about last episode…

[8:00] Telomerase Activation and DNA Methylation Longevity Interventions…

[9:00] Theories of aging/ways to intervene in the aging process…

[10:36] St. Petersburg Institute of Bioregulation and Gerontology…

[11:42] Vladimir Khavison, who he is and what he does…

[13:30] What are peptides?...

[14:00] What was the catalyst for creating bioregulator peptides? The program that created them and some of the first test subjects…

[18:19] How your body uses amino acids as building blocks…

[20:15] Photo of DNA and bioregulator peptide and how they fit together…

[21:15] The influence of peptide bioregulators on morbidity…

[24:11] Can peptide bioregulators restore retinal function?…

[29:30] How are bioregulator peptides sourced?..

[29:34] Epigenetic methylation study, what methylation effects in the body and what can affect methylation…

[39:05] Want to know when you are going to die?..

[44:00] How much do your genes control when it comes to health?..

[49:25] Epigenetic study on gene expression during aging… Looking at DNA age vs chronological age…

[64:58] Human lifespan potential study published by the Smithsonian Magazine…

[66:55] Organ regeneration with bioregulator peptides…

[79:45] Can we live 150 years?.. What can we do to make that happen?..

[89:04] Do some peptides make other peptides more effective?..

[90:00] Nathalie fires off some closing questions such as are allergic reactions possible with bioregulators?…

To purchase Bioregulator Peptides you can use this link https://bit.ly/BioregNN and discount code Longevity15 to save 15% off your first order!

EPISODE SPONSOR:

drinkHRW: For the past 4 years I have been using molecular hydrogen tablets every single day for dozens of reasons including mitigation of oxidative stress, to support my mitochondria and metabolic health, to help me recover from my workouts ....I have every one of my clients using drinkHRW tablets and they all love them too!

Check out their amazing products at drinkHRW.com and use promo code Longevity10 to get 10% off your purchase!

Disclaimer: This podcast and the information presented are for informational purposes only and not intended to diagnose or treat disease. Before making any changes to your nutrition or supplementation please check with your physician or health provider.

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Episoder(330)

#332: Ben Greenfield Reveals Latest Biohacks, Peptide Routines, and Detox Tips for Longevity

#332: Ben Greenfield Reveals Latest Biohacks, Peptide Routines, and Detox Tips for Longevity

If you’ve been anywhere near health optimization circles, you already know Ben Greenfield as a NYT bestselling author, former Ironman triathlete, coach, one of the OGs of biohacking. Today, he’s my guest on the Longevity podcast.   What we discuss: Ben’s new home, cold exposure, and microdosing cryotherapy ... 00:06 Writing, updating, and revising “Boundless” ... 00:09 Key updates: Self-quantification, longevity, new detox protocols ... 00:12 High-tech blood filtration and its impact ... 00:15 Daily detox strategies: Lymphatic movement, sauna, exercise ... 00:17 Ben’s evolution: From strict keto to Mediterranean-style eating ... 00:21 Genetics, ancestry, and personalized nutrition lessons ... 00:23 Impact of endurance training, hormone and gut issues, recovery via flexible dieting ... 00:27 Addressing high coronary plaque: Statins, PCSK9 inhibitors, supplementation ... 00:35 Tracking heart health non-invasively (CIMT) ... 00:38 Thoughtful, limited use of pharmaceuticals for health ... 00:44 Peptides: Orals, protocols, favorites (BPC-157, TA1, etc.) ... 00:47 GLP-1 agonists: Powerful but require careful dosing ... 00:51 Biohacks gone wrong: Dosing mishaps and psychedelic stories ... 00:55 Ben’s three core tips: Family time, naps, and prayer ... 00:58   Our Amazing Sponsors: Wizard Sciences - Mitoblue Everything in the formula is there to help you think clearer, move better, and stay resilient mentally and physically - Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase.   Mitolux NEW Second Generation - This second-generation red and near-infrared light therapy panel hits all the marks. Two new wavelengths—810nm and 940nm—target brain performance, deep muscle recovery, and circulation. I use GAMA mode when I want to lock in focus, and Fireplace 2 when I want to wind down. Get a Mitolux BTS2 Sunlamp for 10% off at https://mitolux.com/NAT10, NAT10 will be automatically applied at checkout.   LVLUP - Neuro Re-Generate the world's first liposomal triple peptide formula, designed to support mental clarity, focus, and overall brain health. Visit www.lvluphealth.com and use code NAT for 10% off your order.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

6 Mai 1h 1min

#331: Can Exosomes Wake Up the Body’s Dormant Healing Powers? Dr. Ed Park Shares Insights On How Exosomes Can Help Heal Intense Pain, Acute Injury, and More.

#331: Can Exosomes Wake Up the Body’s Dormant Healing Powers? Dr. Ed Park Shares Insights On How Exosomes Can Help Heal Intense Pain, Acute Injury, and More.

In this episode, I dive deep into the transformative world of regenerative medicine with Dr. Ed Park—a leader who has spent nearly two decades pushing the boundaries of aging and healing. Curious about exosomes and how these tiny biological messengers are redefining our ability to recover from injury, illness, and even chronic conditions? You’ll love this conversation.   What we discuss: Why exosomes? Origins, discovery, and benefits of stem cells ... 00:03:00 How exosomes communicate and trigger healing ... 00:06:00 Exosomes for neurological repair and brain injuries ... 00:10:00 Exosome delivery: IV, targeting, and blood-brain barrier ... 00:12:00 Exosomes in musculoskeletal injuries and healing rates ... 00:18:00 Patient selection, expectations, and placebo effects ... 00:23:00 Exosomes for immune system support and aging ... 00:30:00 Lifestyle pillars alongside regenerative medicine ... 00:32:00 Exosomes in cardiac and nerve repair ... 00:34:00 Provider training, resources, and Dr. Park’s practice ... 00:43:00 Closing remarks and medical disclaimer ... 00:45:00   Our Amazing Sponsors: Timeline: Mitopure: is a breakthrough supplement that promotes cellular renewal. It contains Urolithin A, which helps your body clear out damaged mitochondria and create new, efficient ones—giving you more sustainable energy. Timeline is offering 10% off your order of Mitopure now. Go to timeline.com/NAT10.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

2 Mai 45min

#330: Lose the Bloat, Fix Your GUT: Inside the Microbiome Revolution (Skin, Weight & Longevity Secrets) with Dr William Davis

#330: Lose the Bloat, Fix Your GUT: Inside the Microbiome Revolution (Skin, Weight & Longevity Secrets) with Dr William Davis

On this episode of the Longevity Podcast, host Nathalie Niddam is joined by renowned cardiologist and bestselling author Dr. William Davis for a deep dive into the powerful connection between gut health, the microbiome, and vibrant longevity. Dr. Davis—who made waves with his groundbreaking books Wheat Belly and Super Gut—shares his journey from mainstream cardiology to pioneering work on the true drivers behind chronic disease, fat gain, and aging.   What we discuss: Meet Dr. William Davis & Wheat Belly origins ... 00:04:00 From cholesterol to calcium scoring ... 00:10:00 Dramatic health wins from removing wheat, grains, sugar ... 00:14:00 Transition to the microbiome & SIBO ... 00:19:00 Modern SIBO causes and prevalence ... 00:24:00 SIBO yogurt strategy and benefits ... 00:31:00 Women’s health, pregnancy, and key microbes ... 00:47:00 Actionable gut health tips and food swaps ... 01:03:00 Fermentation: dos and don’ts ... 01:21:00 Where to find Dr. Davis and wrap-up ... 01:23:00   Our Amazing Sponsors: Peptide Pro App: can help manage every part of your peptide protocol. From smart scheduling to real-time dose checklists, note taking, and easy calculations. Listeners receive 50% off for the first month. Visit www.peptidepro.app to download the app and use code NATHALIE50 to get started today.   Puori - 21 grams of high-quality whey protein from pasture-raised cows with no hormones, GMOs, or pesticides. Ready to ditch the questionable protein powders? Visit Puori.com/NAT and use my code NAT to get 20% off your first order!   Profound Health - Nature’s Marvels have been making bioregulators for over a decade, working directly with Prof. Khavinson, the pioneer of Bioregulator science! They’re manufactured in the UK. They’re GMP and HACCP certified and FDA-compliant. Head to profound-health.com and use code NAT15 for 15% off your first order.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

29 Apr 1h 27min

#329: How C60 Is Changing Aging: Energy, Brain Health, and Recovery Insights With Ian Mitchell

#329: How C60 Is Changing Aging: Energy, Brain Health, and Recovery Insights With Ian Mitchell

In this episode, we’re going deep on Carbon 60—also known as C60 or buckyballs. If you’ve ever wondered how a molecule that started life as an industrial lubricant ended up a star player in the world of anti-aging, you’re in for a treat. Ian and I talk about the original studies that blew everyone’s minds (including a rat study where the animals lived nearly twice as long as expected!), and we discuss Ian’s own hands-on research, from mouse models to dogs, horses, and even human applications.   What we discuss: C60 explained: origins, “buckyballs,” and research ... 00:08 C60 rat and mouse longevity studies ... 00:09 Lipid binding & targeted delivery ... 00:16 C60: antioxidant, adaptogen, mitochondrial effects ... 00:18 Athlete case study & performance benefits ... 00:25 Applications for fatigue, brain fog, metabolic issues ... 00:32 Autoimmune/inflammatory benefits & mitochondrial origins ... 00:34 Hair, scalp, and ovarian health ... 00:38 Neurodegeneration, glymphatics & brain serums ... 00:45 Optimizing cognition & cycling C60 ... 00:51 Safety notes: who should avoid and why ... 00:53 Product lineup & new developments ... 01:01 What to look for in C60 products ... 01:09   Our Amazing Sponsors: LVLUP - Neuro Re-Generate the world's first liposomal triple peptide formula, designed to support mental clarity, focus, and overall brain health. Visit www.lvluphealth.com and use code NAT10 for 10% off your order.   Peptide Pro App - When you’re working with multiple peptides, timing and precision matter. From smart scheduling to real-time dose checklists, it keeps things organized and on track. Receive 50% off for the first month. Visit www.peptidepro.app to download the app and use code NATHALIE50 to get started today.   Wizard Sciences (Neural Rx) - designed to protect your brain long-term. With C60 (an antioxidant) and anti-inflammatory benefits, it combats oxidative stress and helps keep those brain cells healthy and happy. Plus, it supports mitochondrial efficiency, meaning more energy and focus for the long haul. Use code NAT15 at checkout to get 15% off your purchase. Visit wizardsciences.com.    Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

25 Apr 1h 13min

#328: Mastering Facial Rejuvenation: Botox, Fillers, Facelifts & Fundamentals with Dr. Amir Karam

#328: Mastering Facial Rejuvenation: Botox, Fillers, Facelifts & Fundamentals with Dr. Amir Karam

Today, I'm joined by the exceptional Dr. Amir Karam, a genius at the intersection of science and art in facial aesthetics. I've been following Dr. Karam's work for years, and having him on the show feels like a fantastic opportunity to explore why our faces age and what we can truly do to maintain a youthful appearance.   What we discuss: Dr. Amir Karam's Background ... 00:07:35 Facial Rejuvenation Evolution ... 00:08:46 Historical Context of Facelifts ... 00:09:20 Vertical Approach in Rejuvenation ... 00:12:37 Genetics and Aging ... 00:20:39 Importance of Skin Care ... 00:23:00 Fillers' Long-Term Impact ... 00:34:04 Botox Best Practices ... 00:42:19 Skin Care Techniques ... 00:46:31 Light Therapy and Microcurrent ... 00:47:01 Diet and Skin Health ... 01:00:44 Surgical Outcomes and Longevity ... 01:17:29   Our Amazing Sponsors: Troscriptions - Blue Cannatine - think of it as a small but mighty brain boost that melts in your mouth. A precise blend of methylene blue, caffeine, CBD, and microdosed nicotine gives me steady energy, focus, and mental clarity without the usual ups and downs. Visit  troscriptions.com and use code NAT10 for 10% off. Get in the zone and stay there.   Qualia - NAD+ This vital molecule powers cellular energy, supports DNA health, aids detox, and helps keep your body remain youthful. Visit qualialife.com/nathalie to try Qualia NAD+, backed by a 100-day money-back guarantee, and use promo code NATHALIE for 15% off!   Quantum Upgrade - Imagine plugging yourself into a limitless power source rigorously tested and shown to improve blood flow, reduce stress, and even boost cellular energy by up to 29%. Try it today at quantumupgrade.io/NAT and start running life, instead of life running you. Use my code NAT15 to get a 15-day free trial on the All-in-One Frequency Bundle. Good through June 1st, 2025   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

22 Apr 1h 23min

 #327: Testosterone for Women: Enhancing Strength, Libido, and Cognitive Function With Nat Niddam

#327: Testosterone for Women: Enhancing Strength, Libido, and Cognitive Function With Nat Niddam

Hey there, Longevity Podcast listeners! It's just me, Nathalie Niddam, in today's episode, diving into a subject that's often overlooked but super important—testosterone in women. Yes, you heard that right! While most people think of testosterone as a "male" hormone, it plays a crucial role in women's health, especially as we navigate through menopause.   What we discuss: Testosterone in Women ... 00:00:37 Muscle Challenges ... 00:02:10 Sexual Function ... 00:04:33 Energy Levels ... 00:05:14 Cognitive Function ... 00:05:56 Mood and Bone Health ... 00:05:56 Muscle and Cardiovascular Health ... 00:07:02 Somatic Symptoms ... 00:09:01 Sleep and Motivation ... 00:10:14 Cautions with Therapy ... 00:11:13 Administration Methods ... 00:14:38 Transdermal vs. Injectable ... 00:16:47   Our Amazing Sponsor: BiOptimizers - MassZymes is the most complete, most potent digestive enzyme with over 102% MORE PROTEASE than the nearest competitor. That’s crucial because protein is the most complex macronutrient to break down. Try MassZymes at bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

18 Apr 26min

#326: From Brain Fog to Focus: Techniques and Supplements to Enhance Cognitive Function With Kyal Van Der Leest

#326: From Brain Fog to Focus: Techniques and Supplements to Enhance Cognitive Function With Kyal Van Der Leest

In this episode of the Longevity Podcast, I sit down with my good friend and brilliant supplement formulator, Kyal Van Der Leest, who's known for his innovative work in the peptide space. Together, Kyal and I explore the fascinating world of brain health and uncover powerful strategies to boost cognitive function.    What we discuss: Mold toxicity and health effects ... 00:03:49 Kyal's journey and Level Up Health ... 00:04:26 Lifestyle factors in brain health ... 00:19:19 Role of BDNF in neuroplasticity ... 00:24:44 Overview of neurotransmitters ... 00:30:12 Tessa Fensin and market withdrawal ... 00:39:01 Peptides for brain health ... 00:46:18 Blood flow and botanicals ... 00:53:06 Liposomal delivery benefits ... 01:06:22 Creatine for brain health ... 01:13:02 Kyal's supplement quality commitment ... 01:19:04 Conclusion and product info ... 01:26:00   Our Amazing Sponsors: Timeline: Mitopure is a breakthrough supplement that promotes cellular renewal. It contains Urolithin A, which helps your body clear out damaged mitochondria and create new, efficient ones—giving you more sustainable energy. Timeline is offering 10% off your order of Mitopure now. Go to timeline.com/NAT10.   Wizard Sciences (Neural Rx) - isn’t just about a quick boost. It’s designed to protect your brain long-term. With C60 (an antioxidant) and anti-inflammatory benefits, it combats oxidative stress and helps keep those brain cells healthy and happy. It supports mitochondrial efficiency, for more energy and focus for the long haul. Use code NAT15 at checkout to get 15% off your purchase. Visit wizardsciences.com.   Young Goose L.A.D.R. Serum -  Powered by light-activated DNA repair enzymes, NAD+, and collagen peptides, it reverses damage. Sunlight? Red light therapy? It all helps this serum work smarter, not harder. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you’re an existing customer. Future-proof your face.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

15 Apr 1h 27min

#325: No More 3PM Burnout: How to Have A Successful Workday AND Energy Left for What Matters Most At The End Of The Day with Greg Kelly

#325: No More 3PM Burnout: How to Have A Successful Workday AND Energy Left for What Matters Most At The End Of The Day with Greg Kelly

Today’s guest, Dr. Gregory Kelly, creator of Qualia Mind, has spent years studying how to help people think faster, age better, and avoid that 3 p.m. crash that turns you into a zombie.  If you’ve ever wished for an extra gear in your mental engine, this is the episode for you! And if you are interested in giving it a try, visit qualialife.com/nathalie and use promo code NATHALIE to save 15% on your order.    What we discuss: Difference Between Brain and Mind ... 00:07:03 Mental Energy and Brain Function ... 00:09:49 Glucose and Ketones as Brain Fuel ... 00:17:45 Nootropic Supplements and Their Impact ... 00:24:53 Stacking Compounds for Cognitive Performance ... 00:34:07 Short-term and Long-term Benefits of Ingredients ... 00:43:18 Using Nootropics Like Qualia Mind for Performance ... 00:52:28 Safety and Effectiveness of Ingredient Stacking ... 01:16:40 Five Tips for Maintaining Cognitive Energy ... 01:19:15 Conclusion and Final Thoughts ... 01:26:28   Our Amazing Sponsors: STEMREGEN - Triggers the release of 10 million of your own stem cells, supporting tissue repair, recovery, and overall longevity. Visit stemregen.co/NAT15 and use code: NAT15 for 15% off your order.   BEAM - These minerals come from humate, a natural substance formed over millions of years as freshwater plants broke down and deposited their nutrients into the soil. Over time, those minerals concentrated into this black, crystalline material that’s now one of the most mineral-dense substances on earth. Visit https://www.beamminerals.com/NAT20 and use code NAT20 for 20% off.   Profound Health - Nature’s Marvels have been making bioregulators for over a decade, working directly with Prof. Khavinson, the pioneer of Bioregulator science! They’re manufactured in the UK. They’re GMP and HACCP certified and FDA-compliant. Head to profound-health.com and use code NAT15 for 15% off your first order.   Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

11 Apr 1h 28min

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