Direct Line April 2026: Stopping Ozempic and Lifting With Osteopenia
Stop a GLP-1 and about two thirds of the weight loss comes back within a year. Three randomized withdrawal trials (SURMOUNT-4, STEP 1 extension, STEP 4) and a new BMJ 2026 systematic review of 37 RCTs...
21 Apr 38min
Is the Testosterone Crisis Real? The Numbers Behind the Headlines | Signal Ep 1
A quarter of men start testosterone without a single lab test. Most boosters don't work. And the "testosterone crisis" headline is half testing artifact, half waistline. Two physicians walk through wh...
14 Apr 40min
Medical Mystery: The Man Who Got Weaker When He Started Training
A 43-year-old man starts exercising and ends up in the ER with a CK over 100x the upper limit of normal. His doctor says it’s from training. We don’t think so. In this episode, Dr. Jordan Feigenbaum a...
7 Apr 1h 15min
Overtraining Syndrome: Causes, Diagnosis, and What's Actually Going On
In 2022, researchers conducted the most rigorous systematic review ever performed on overtraining syndrome — looking specifically for controlled studies that documented a human transitioning from a he...
31 Mar 1h 36min
Episode #391: VO2 Max vs. Cardiorespiratory Fitness, GLP-1 Costs, and the 10,000-Step Myth | Direct Line March 2026 (Free)
In this free preview of the March 2026 Direct Line AMA. Drs. Feigenbaum and Baraki cover: VO2 max versus cardiorespiratory fitness for longevity (are Peter Attia’s targets evidence-based? — with Goodh...
24 Mar 30min
Episode #390: Why Your Waist Matters More Than Your Weight — The Science of Visceral Fat
You can have a completely normal BMI and be on your way to cardiovascular disease, type 2 diabetes, and metabolic syndrome without triggering a single alert on a standard health screening. The fat tha...
17 Mar 44min
Episode #389: Your Liver Enzymes Are Elevated — But It Might Not Be Your Liver
A fit, healthy 39-year-old was nearly sent for a liver biopsy. The cause? Was it that he went to the gym before every blood draw or because his supplement was throwing his labs off?. Dr. Jordan Feigen...
9 Mar 1h 1min
Episode #388: Muscle Imbalances, Red Meat Risk, and the Science of Body Fat Set Points
In this special preview of the Barbell Medicine Plus Direct Line, Dr. Jordan Feigenbaum and Dr. Austin Baraki move past the fitness basics to tackle high-level technical nuances. We dive into the pers...
26 Feb 34min
