Part 55 - Dr. Anthony Jay on Decoding your DNA, Avoiding Male Feminization, and Epigenetics

Part 55 - Dr. Anthony Jay on Decoding your DNA, Avoiding Male Feminization, and Epigenetics

Hey everyone out there in podcast land, we're back for another great episode. I had the pleasure of speaking with Dr. Anthony Jay this week. He's probably best known for his book Estrogeneration where he explores how all the nasty xenoestrogens creep into our body through plastics, food like soy, personal care products, sunscreen, the water, etc. This is important stuff because you may think it doesn't affect you, but it does, and you just don't realize it. You don't have to go crazy over this stuff, but it's best to minimize your exposure.

What was really cool for me is that I got to talk to him before and after the show and realized what a great wealth of knowledge he has on so many subjects - which is also very apparent throughout the episode. We could have talked all day, but we cut ourselves off at 2 solid hours of hot nutrition talk.

Dr. Jay earned his Ph.D. in Biochemistry from Boston University School of Medicine, researching fats, hormones, and cholesterol. He's currently at the Mayo Clinic in Rochester, Minnesota researching stem cells, epigenetics, and infrared light. He also does DNA consulting which I'm going to do with him in the near future.

So now for a huge announcement - the SAPIEN show is finally here! I haven't mentioned it much, but it's been in the works for a while. It's recorded on video and audio at SAPIEN headquarters at Evolve Healthcare in Woodland Hills, California with in-person guests.

My co-host is the one and only Dr. Gary Shlifer who was a recent Peak Human guest. By far the most positive feedback of any episode. Go back and listen if you'd like (it's episode 48) or just jump in and start with the Sapien podcast that is launching today!

So I'd suggest pausing this episode and subscribing now before you forget. Go ahead, I'll wait. Just look up Sapien in any podcast app or on youtube. The podcast version has higher quality audio and the youtube version has our smiling faces! We already have a bunch of great episodes in the bag, including one where Dr. Paul Saladino and Dr. Gary get in a small war. It got awkward after that one.

My other co-host is Yaniv Fituci, the producer of Food Lies and co-founder of http://Attack.Media

He produces shows for Disney, Sony, Nintendo and all that other Hollywood stuff. He'll be coming in and out and bringing his awesome perspective into the mix.

So I'll keep it quick this week on how to support this show, myself, and all things Sapien. My main venture is the sapien organization which can be found at http://sapien.org which includes the Food Lies film, Nose to Tail grass finished meat, this podcast, and even the long term vision of changing the way we farm with the Sapien Movement. You can find out more about the Sapien Diet there which people have been asking about. I posted my before and after picture on instagram, facebook, and twitter to show what happens when you eat densely and move intensely and live a Sapien Lifestyle, which is how us modern homo sapiens in 2019 should be living. I swear it's the easiest thing to do once you understand what to do and why you're doing it. I eat the most delicious meals I can imagine until I'm full, never worry about calories or macros, then go work out for 17 minutes most weekdays… and this helped me transform my body and my life.

So start eating densely with all the grass finished meat on http://NoseToTail.org support this podcast so I can keep doing it at http://patreon.com/peakhuman preorder the film so we can finish it - the more funds we have, the sooner it will come out. You can click through to the Indiegogo at http://FoodLies.org and subscribe to the new Sapien show on any podcast app and the Food Lies YouTube channel.

Without further ado, please welcome the superb Dr. Anthony Jay.

BUY THE MEAT NosetoTail.org

Support me on Patreon! http://patreon.com/peakhuman

Preorder the film here: http://indiegogo.com/projects/food-lies-post

SHOW NOTES

  • Dr. Anthony Jay is currently a researcher at the esteemed Mayo Clinic
  • He received his Phd at Boston University School of Medical in Biochemistry
  • Anthony's definition of cholesterol and why it is absolutely essential
  • Why dietary cholesterol does not directly affect your blood cholesterol in a harmful way
  • How harmful exposure from estrogen is all around you whether it be everyday use products, your environment, diet or water supply
  • Fake estrogen (man-made chemicals) are harming you in products you would never expect
  • Why scientists, researchers, and governmental standards tend to ignore the negative effects of these everyday products and how they manage to stay on shelves
  • Explanation of how the problem lies with the slow buildup of these artificial estrogens in the body long term
  • How artificial estrogens alter sex hormones and can lead to male feminization
  • How Epigenetics work and instances it has been shown in history
  • You can read more about one of the first instances of Epigenetics here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579375/
  • How methylation changes creates physical marks on DNA which lead to increases in DNA mutations and epigenetic alterations
  • How Atrazine, a widely used herbicide in North American agriculture (but illegal in Europe) is harming current and future generations
  • How estrogen directly influences PPAR-gamma (Peroxisome Proliferator-Activated Receptor Gamma) to store more fat
  • How estrogen affects SHBG (Sex Hormone Binding Globulin) and leads to lower testosterone
  • Why 4-Methylbenzylidene-camphor is being outlawed in Hawaii, Australis, New Zealand, Philippines, and the Caribbeans
  • How xenoestrogen compounds are even being found in polar bears in northern Alaska
  • Why Dr. Anthony Jay stopped using sea salt due to microplastics
  • How a pristine mountain lake in Switzerland with little to no human contact had its male fish somehow becoming female
  • Atrazine in even relatively low doses compared to US agriculture can still lead to male frogs to become female
  • How religious dogmatism in scientific community leads to little or no discourse about these types of issues
  • What Dr. Anthony Jay's power rankings of dangerous xenoestrogens are
  • Check out what everyday products he uses and feels safe about at: AJconsultingcompany.com/whatiuse
  • Learning about your genetic predispositions and how to cater your diet, supplements, and lifestyle to best fit your genetics is an effective way to live a healthier, longer life
  • How ancestry.com analyzes your genetics and allows you to get it looked at by professionals such as Dr. Anthony Jay to customize your own diet and supplementation
  • Iodine and Vitamin D are essential
  • The importance of cycling in and out of ketosis and being able to get fat adapted/metabolic flexibility
  • Reasoning behind intermittent fasting
  • Developing a foundation of strength - the big 6: squat, deadlift, bench, row, pull-down, overhead press
  • Why there is no such thing as a perfect diet for everybody
  • How to optimize sleep and why it's important
  • What flavonoids are and why he suggests them for most people
  • How you can optimize your testosterone
  • Heavy metal exposure can lead to testosterone to drop
  • How having too much of essential micronutrients can drop testosterone
  • Why you should avoid BPA, BPS, BPF and phthalates
  • If you want to learn more go check out his book "Estrogeneration: How Estrogenics are Making You Fat, Sick and Infertile"
  • Find him at http://ajconsultingcompany.com

BUY THE MEAT NosetoTail.org

Support me on Patreon! http://patreon.com/peakhuman

Preorder the film here: http://indiegogo.com/projects/food-lies-post

Film site: http://FoodLies.org

YouTube: https://www.youtube.com/c/FoodLies

Sapien Movement: http://SapienMovement.com

Follow along:

http://twitter.com/FoodLiesOrg

http://instagram.com/food.lies

http://facebook.com/FoodLiesOrg

Theme music by https://kylewardmusic.com/

Episoder(233)

Sapien Podcast - Simplicity, Discipline & Living Fit Past 40 with Chris Kruger

Sapien Podcast - Simplicity, Discipline & Living Fit Past 40 with Chris Kruger

In this episode of Sapien Podcast, Brian Sanders and Chris unpack how to simplify health in a noisy world. They discuss intermittent fasting, the truth about cardio, testosterone, and why building muscle is the foundation for longevity. Chris and Brian share their personal journey, practical tips for busy men, and the philosophy that has helped thousands transform their lives by doing less, but better.   Show Notes: 04:00 The Ten Commandments of Health – Simplicity Over Complexity 07:30 Why Discipline Brings Freedom in Health and Life 10:15 Eating Real Food vs. Diet Dogma 13:40 Intermittent Fasting, Energy, and Recovery 17:20 Muscle as the Anchor of Longevity 20:00 Cardio Myths and Why Strength Training Wins 24:00 Testosterone, Aging, and Building Vitality After 40 28:00 Lifestyle Habits That Compound Over Time 32:00 The Role of Faith, Family, and Community in Health 36:00 Why Simplicity Is the Ultimate Sophistication

4 Nov 35min

Part 229 -Reviving Regenerative Agriculture with Will Harris

Part 229 -Reviving Regenerative Agriculture with Will Harris

Will Harris is known for his pioneering regenerative agriculture practices. The episode explores Harris's journey from traditional farming to regenerative agriculture, the economic challenges, and the impact on land, community, and ecosystems. Harris shares insights from his experiences, including his transition away from chemical-dependent farming and the development of vertically integrated operations. They discuss the benefits of regenerative practices, the difficulties in marketing and scaling, as well as the broader implications for nutrition and sustainability. Lastly, the episode addresses the sustainability of feeding the world through regenerative practices, emphasizing local community support and the long-term generational benefits. 05:10 Introduction to Will Harris 09:05 Challenges and Evolution in Farming Practices 29:43 The Impact of Erosion on Soil Health 30:09 Scientific Comparison: Monocrop vs. Diverse Ecosystem 30:48 Economic Challenges of Transitioning to Regenerative Farming 31:49 The Rise of Grass-Fed Beef and Market Challenges 33:00 Educating Consumers on Grass-Fed Beef 35:03 The Influence of Propaganda on Food Choices 42:18 The Role of Debt in Farm Management 44:15 Challenges in Poultry Farming 50:31 The Benefits of Regenerative Agriculture 53:31 Feeding the World Sustainably 01:00:20 Reflections on the Future of Regenerative Farming BEEF TALLOW PRODUCTS: NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

29 Okt 1h 2min

Sapien Podcast- Fiber Myths, Vitamin C Lies, and the Fight for Root-Cause Health with Chris Kruger

Sapien Podcast- Fiber Myths, Vitamin C Lies, and the Fight for Root-Cause Health with Chris Kruger

In this episode of the Sapien Podcast, Chris Kruger returns as co-host with Brian Sanders for a deep dive into nutrition myths, fiber fallacies, and the failures of mainstream dietetics. Together, they expose how official guidelines and academic institutions push confusion for profit while ignoring root-cause solutions. The hosts critique health narratives around fiber, red meat, vitamin C, and weight-loss drugs, while sharing client case studies that reveal the real path to metabolic health. They emphasize the Sapien approach: whole foods, animal-based nutrition, hormone balance, and lifestyle over pills and procedures. SHOW NOTES: 04:00 The Football Analogy: nutritionists misunderstand cause and effect 06:00 Debunking fiber myths and why whole foods matter most 09:00 Case study: reversing lifelong constipation with a low-fiber diet 12:00 Red meat, healthy user bias, and flawed nutrition studies 14:30 Academia, food industry funding, and distorted guidelines 15:30 Carnivore diets and the vitamin C myth 18:00 Beyond "calories in, calories out" 27:00 Defining metabolic syndrome vs. metabolic excellence 30:00 Statins, side effects, and why lifestyle beats prescriptions 32:00 Hormone health as the foundation of motivation and vitality BEEF TALLOW PRODUCTS: NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

27 Okt 37min

Sapien Podcast- Fitness Wisdom Unplugged

Sapien Podcast- Fitness Wisdom Unplugged

In this episode of the Sapien Podcast, Chris Krueger joins the show as a new co-host along with host Brian Sanders. They introduce the podcast as a fun, unplanned discussion about health, fitness, and hormone optimization. The hosts share personal fitness stories and emphasize the importance of a holistic approach to health, advocating for living naturally and avoiding artificial supplementation like TRT. They critique Brian Johnson's extreme health regimens and promote practical, actionable steps for achieving and maintaining elite health without extensive gym workouts or complex diet plans. SHOW NOTES: 00:00 Introduction to the Sapien Podcast 01:11 Fitness and Hormone Optimization 01:25 Generational Fitness and Relatability 01:43 Chris's Fitness Feats and Midlife Reflections 04:57 The Importance of Staying Active 05:38 Family Dynamics and Health Advice 08:01 The Sapien Lifestyle and Hormone Balance 14:16 Insulin and Metabolic Health 17:31 Raw Milk and Sapien Center Community 18:42 Farmer's Market Raw Milk Prices 20:43 Brian Johnson's Cult-Like Brunch 22:03 The Profit in Food Processing 25:31 Debunking Diet Myths   BEEF TALLOW PRODUCTS: NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post    Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies   Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

22 Okt 35min

Part 228 - Dr. Doug McGuff on High-Intensity Training, Recovery, and the Truth About Nutrition

Part 228 - Dr. Doug McGuff on High-Intensity Training, Recovery, and the Truth About Nutrition

Dr. Doug McGuff is an emergency physician, exercise researcher, and co-author of Body by Science. Known for his pioneering work in high-intensity resistance training, McGuff blends decades of medical practice with deep knowledge of physiology to reveal how short, focused workouts can yield extraordinary health benefits. He also runs training studios in South Carolina that specialize in safe, supervised strength training. In this episode of Peak Human, Brian Sanders and Dr. McGuff dive into why most people misunderstand exercise, the dangers of overtraining, and how nutrition and movement fit together for long-term health. They cover everything from the "12-minute workout" to the role of myokines, why VO₂ max is misunderstood, and how subsidies and processed foods hijacked the human diet. This conversation reframes what it truly means to build strength, resilience, and health for life. Show Notes: 03:00 Dr. McGuff's Background: Emergency Medicine & Strength Training 07:00 Adaptive Resistance Training (ARX) & How It Works 14:00 The Physiology of Strength: Motor Units & True Failure 22:00 The "12-Minute Workout" – Time Efficiency & Maximum Results 25:00 Overtraining, PEDs, and the Myths of Modern Fitness Culture 28:00 Long-Term Damage from Inefficient Training Methods 30:00 You Can't Out-Exercise a Bad Diet 33:00 The Straight Line Between You and the Sun – Whole Food Nutrition 44:00 Debunking the Meat & Gout Myth 48:00 Eat Densely, Move Intensely – Rethinking Fitness Advice 49:00 Cardio Myths, VO₂ Max, and the Zone 2 Obsession 56:00 What Really Correlates With Longevity: Adaptation, Not Numbers BEEF TALLOW PRODUCTS: NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

24 Sep 1h 14min

Part 227 - Holistic Health, Slow Food, and Lifelong Vitality with Tara Couture

Part 227 - Holistic Health, Slow Food, and Lifelong Vitality with Tara Couture

In this episode of Peak Human, host Brian Sanders welcomes back Tara Couture. Tara, a renowned advocate for the Sapien lifestyle, shares insights into her holistic approach to health, which includes growing her own food and embracing a nutrient-dense diet. The discussion covers various topics, including nutrition, lifestyle factors, nature, hormone optimization for both men and women, and practical tips for adopting this lifestyle even in urban settings. Tara also discusses her new book, 'Radiance of the Ordinary,' which explores the profound rewards of living authentically and nourishing one's body. Brian also highlights the benefits of natural supplements like oyster pills for hormone optimization. A must-listen for anyone interested in sustainable living and holistic health. Show Notes: 00:15 Tara's Lifestyle and Farmstead 00:59 Nutrition and Lifestyle 07:46 Raising Healthy Children 15:36 Cooking and Food Preparation 31:45 Travel and Eating Healthy 35:10 Carbs and Diet Adjustments 36:42 Exploring the Benefits of Carbs 38:00 Introducing Tara's Book: Radiance of the Ordinary 38:46 The Dichotomies of Life and Embracing Mortality 43:33 The Importance of Real Food and Nutrition 48:13 Men's Health and Hormones 57:41 The Simplicity of Whole Foods 01:05:54 The Gift of a Healthy Body BEEF TALLOW PRODUCTS: NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies Tara's Book: https://www.penguinrandomhouse.com/books/798098/radiance-of-the-ordinary-by-tara-couture/ Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

3 Sep 1h 12min

Part 226 - Biohacking and Homesteading: Bridging the Gap with Michael Kummer

Part 226 - Biohacking and Homesteading: Bridging the Gap with Michael Kummer

In this episode, Brian Sanders chats with Michael Kummer about his multifaceted approach to health and wellness, which combines elements of biohacking, fitness, and homesteading. Kummer, a proponent of the 'Sapien' philosophy, emphasizes a diet and lifestyle that closely mimic natural human behaviors. The discussion covers Michael's fitness routine, which involves minimal gym time, his creation of an accessible fitness program, and his unique perspective on the synergy between biohacking and homesteading. They delve into the issue of modern diets, stress, and lifestyle factors impacting health, using Austria as a case study to highlight these trends. Kummer also shares insights into his family's transition to a homesteading lifestyle and offers practical tips for integrating these principles into various lifestyles.   Try the oyster pills! https://nosetotail.org/products/pure-oyster   Show Notes: 02:18 Biohacking vs. Natural Living 04:12 Homesteading and Food Production 08:45 Health Impacts of Modern Lifestyle 12:03 Traditional Food Preparation Techniques 24:41 The Importance of Muscle Mass 28:12 Austrian Lifestyle and Longevity 33:02 Traditional Austrian Diet: Then and Now 33:16 Impact of World War II on Diet and Lifestyle 35:32 Modern Austrian Diet and Health Trends 37:46 Comparing Health Outcomes: Austria vs. USA 45:38 Personal Fat Threshold and Its Implications 51:52 Homesteading and Sustainable Living 54:21 Balancing Modern Life with Traditional Practices 58:21 The Role of Community in Homesteading 01:03:13 Supplements and Whole Foods for Optimal Health   BEEF TALLOW PRODUCTS: NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post    Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies   Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

13 Aug 1h 6min

Part 225 - Unlocking the Secrets of Satiety Per Calorie with Dr. Ted Naiman

Part 225 - Unlocking the Secrets of Satiety Per Calorie with Dr. Ted Naiman

In this episode of Peak Human, host Brian Sanders interviews Dr. Ted Naiman, discussing the concept of satiety per calorie and its implications for diet and health. They dive into the importance of understanding different diet patterns, focusing on high-protein, nutrient-dense foods, and avoiding overly processed foods. The conversation covers the four pillars of satiety per calorie: protein percentage, energy density, fiber content, and hedonics. Dr. Naman also talks about his new book 'Satiety Per Calorie,' which aims to provide a comprehensive understanding of diet and nutrition, helping people make informed food choices to maintain optimal body composition effortlessly. The episode concludes with discussions on the benefits of natural exercise routines and natural supplements for overall health.   Try the oyster pills! https://nosetotail.org/products/pure-oyster   Show notes   00:28 Understanding Diets and Nutrition 01:28 Exercise and Fitness Insights 02:09 Oyster Pills and Testosterone Boost 03:15 Daily Life and Health Philosophy 03:53 Satiety and Nutrient Density 05:38 The PE Diet and Satiety Per Calorie 06:34 Explaining Diet Patterns and Health Outcomes 12:48 Practical Tips for Diet and Exercise 41:09 Understanding Protein Leverage and Obesity 44:07 Can You Get Fat on Protein? 45:47 Nutrient Calories vs. Energy Calories 49:33 The Four Pillars of Satiety Per Calorie 54:42 The Role of Fiber in Satiety 01:01:38 Energy Density and Caloric Intake 01:07:01 The Liver's Role in Metabolism   REGENERATIVE PRODUCTS: NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post    Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies   Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

6 Aug 1h 14min

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