Ep 125 Blastomycosis: How fungus became amongus

Ep 125 Blastomycosis: How fungus became amongus

Fungal infections don’t often make an appearance on this podcast, but when they do, you know you’re in for a wild ride. In this episode, we explore the rare but potentially deadly fungal infection blastomycosis. We trace the journey of Blastomyces spores as they depart from their cozy homes of decomposing wood and make their way first into mammalian lungs before possibly moving into the skin, intestines, and brain. How and why these fungi can be so deadly is our next stop, one that takes us into an unexpected direction: the fall of dinosaurs, the rise of mammals and the role that pathogenic fungi played in this transition. We delve into why comparatively few fungi are pathogenic to humans and how our warm-bloodedness may protect us. But, as we discuss in the episode’s conclusion, that protection may be weakened as our warming planet selects for fungi that can tolerate increasing temperatures. Dinos, dogs, deep time, and deadly outbreaks - this episode has it all.

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Special Episode: Adam Kucharski & Proof

Special Episode: Adam Kucharski & Proof

Why do we believe what we believe? Is what we believe the truth? How can we convince others of our beliefs? If you’ve ever found yourself pondering these questions, you know that the answers are rarel...

21 Apr 50min

Ep 207 Tear Gas: How can a chemical weapon be “humane”?

Ep 207 Tear Gas: How can a chemical weapon be “humane”?

Tear gas is an expected, normalized part of protests today. But its use in international war is banned. How can that be? That’s just one of the questions we investigate in this episode. First, we take...

14 Apr 1h 15min

Ep 206 Oropouche Virus: More than a smidge worrisome

Ep 206 Oropouche Virus: More than a smidge worrisome

Though discovered relatively recently, Oropouche virus has been making headlines as an emerging vector-borne infectious disease on the rise. Not transmitted by the usual suspects (like ticks and mosqu...

7 Apr 1h 12min

Ep 205 Cancer Part 4: Where do things stand today?

Ep 205 Cancer Part 4: Where do things stand today?

For the entirety of our species’ history, our approach to cancer has largely been to react, to design new therapies and better combinations of treatments. This energy has certainly been well-spent, bu...

31 Mars 1h 19min

Ep 204 Cancer Part 3: How do we treat it?

Ep 204 Cancer Part 3: How do we treat it?

A century and a half ago, the list of effective cancer treatments was essentially a single entry: surgery. Today, in 2026, you’d need pages to contain the number of treatments available, and multiple ...

24 Mars 1h 32min

Special Episode: Lawrence Ingrassia & A Fatal Inheritance

Special Episode: Lawrence Ingrassia & A Fatal Inheritance

For centuries, physicians noticed that cancer sometimes ran in families, but until the 1960s, an answer to this mystery remained out of reach. Only then were scientists beginning to unlock the cellula...

17 Mars 45min

Ep 203 Cancer Part 2: Why does it happen?

Ep 203 Cancer Part 2: Why does it happen?

Each of our cells can become cancerous. It’s an uncomfortable, yet unavoidable truth. Nor is it a truth restricted to our species - cancer is a consequence of complex life. The features that make a ce...

10 Mars 1h 18min

Ep 202 Cancer Part 1: What is it?

Ep 202 Cancer Part 1: What is it?

Cancer has touched every one of us in some capacity, and learning of a diagnosis inspires many more questions than it answers. In this four-part series on cancer, we aim to lay a foundation of knowled...

3 Mars 1h 36min

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