009 The Case of the False Negative Celiac Test w/ Dr. Peter Osborne

009 The Case of the False Negative Celiac Test w/ Dr. Peter Osborne

The Case:

  • Diana is 36 and suffers from irregular bowel movements and stomach upset.
  • Endoscopies, colonoscopies and genetic testing for celiac disease provided no answers
  • She tried adjusting her diet but nothing has helped and her doctor was stumped.

My first suspicion was that her Celiac test was a false negative or that she had some underlying gluten-sensitivity. Gluten is found in wheat, rye, barley and oats and many people may have the sensitivity. It’s estimated that 30 – 40% of people are genetically positive for gluten-sensitivity. Many go undiagnosed.

Dr. Peter Osborne is world renown in the field of gluten and grain sensitivity. He is the author of the highly acclaimed bestseller, ‘No Grain, No Pain’ and is a Doctor of Chiropractic and board certified in clinical nutrition and pastoral medicine. He is the clinical director of Origins Healthcare in Sugarland, Texas and is also an advisor for Functional Medicine University.

He joins me in the discussion of this case to share his significant expertise in this field.

Confusion Around Gluten Terminology

Many people mislabel conditions relating to gluten and mistakenly use gluten-sensitive, gluten-intolerant, gluten allergy, and celiac interchangeably. So, what is the difference between gluten sensitivity and gluten allergy? What’s the difference between gluten intolerance and celiac disease?

Dr. Osborne explains that gluten sensitivity is a state of genetics which is not a disease. However, this sensitivity can lead to the development of celiac disease which is an autoimmune disease. Gluten intolerance is a reaction to gluten without the genetic disposition. The body cannot digest gluten properly because it is not producing the necessary enzyme. This can result in irritable bowel, gas, bloating and other intestinal discomforts. An allergy to gluten it very rare. Classically, this would show up as an acute response similar to other food allergies which often have symptoms like hives, swollen lips, and throat constriction. It’s potentially life-threatening.

Traditional Testing for Celiac is Insufficient

Most doctors will test two genetic markers for celiac disease but there are 5 antibodies that should be tested. Some people, like Diane, are told they don’t have Celiac disease and can eat gluten when that is not the case. Comprehensive tests that specifically include HLA DQ2 and DQ8 as well as the wheat zoomer (see below for links to these tests) are needed to completely rule out gluten issues. These tests are a simple cheek swab and a blood test.

Gluten Sensitivity due to Genetics is Permanent

While some people may feel better after giving up gluten for a period of time, this does not mean they can return to eating gluten. Dr. Osborne says that it can’t be reversed and his best advice is to stay away from it if they want to maintain their health. Eating gluten (for those that have the gluten genes) is unhealthy for them so if they go back to it, they’ll soon feel the repercussions of their unhealthy ways.

Consider the Quality of Grains

People who do not have the genetic markers for gluten sensitivity, antibodies to gluten, or the presence of autoimmune disease do not need to follow a gluten-free diet. However, it’s important to look at the quality of the food they’re eating. Grains can have mold or mycotoxins (see episode 006). They may also have trace amounts of pesticides that could include glyphosate which has been linked to cancer, neurodegeneration and fertility issues. In addition to that, many grains have been genetically modified.

You Can’t Just Take a Pill

There are enzymes available in supplement form that will help the body digest gluten. While this might seem like a ‘get out of jail free’ card, it’s not. If you have a gluten sensitivity or Celiac disease these are meant only to protect you against unwitting exposure (often through cross contamination in non-gluten-free restaurants or homes). It’s not a magic pill that you can take and then go devour a pizza. Sorry, guys.

Eliminating Health Mysteries

For Diana we were able to get to the real root of the problem and help her regain her health. Could a gluten sensitivity be the missing clue for you or someone in your life? Please share this episode with them so that they can feel better too.

Links:

Resources mentioned

Thanks to my guest Dr. Peter Osborne. You can connect with him through his website: https://drpeterosborne.com/

You can get a copy of his book No Grain, No Pain here:

www.glutenfreesociety.com

Thanks for Listening

If you like what you heard, please rate and review this podcast. Every piece of feedback not only helps me create better shows, it helps more people find this important information.

Never miss an episode – Subscribe NOW to Health Mysteries Solved with host, Inna Topiler on Apple Podcasts, Spotify, Stitcher or Google Podcasts. Find out more at http://healthmysteriessolved.com

Overcoming Hashimoto’s Summit

Claim your free spot to this 7-day virtual summit featuring the top experts in Hashimoto’s and Hypothyroidism so that you can overcome this diagnosis and feel better.

https://bit.ly/2KigemW

PLEASE NOTE

All information, content, and material on this podcast is for informational purposes only and is not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified physician or healthcare provider.

Some of the links provided are affiliate links. This means we may make a very small amount of money should you choose to buy after clicking on them. This will in no way affect the price the product but it helps us a tiny bit in covering our expenses.

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197 What No One Told You About The Connection of Progesterone, Estrogen, and Hashimoto’s with Dr. Felice Gersh (Part 1)

197 What No One Told You About The Connection of Progesterone, Estrogen, and Hashimoto’s with Dr. Felice Gersh (Part 1)

In this episode of Thyroid Mystery Solved, Inna welcomes back the brilliant Dr. Felice Gersh for a conversation that takes Hashimoto’s and hormones to a whole new level. Together, they dive deep into the role of estrogen and progesterone in regulating the immune system, inflammation, and thyroid health. Most people have only heard the basics about these hormones, but as Dr. Gersh explains, the story goes far beyond reproduction. From Hashimoto’s flares that appear around menstrual cycles to the critical impact of hormones during perimenopause and menopause, this discussion unpacks what most doctors never tell their patients and you are going to be amazed!Dr. Gersh also shines a light on how misconceptions about hormones, especially progesterone, have shaped conventional medicine and why so many women are left without the support they truly need. This episode is part one of a two-part series, and it is filled with insights that will completely change the way you think about hormones and Hashimoto’s.----------For full show notes, please see https://innatopiler.com/podcasts/connection-progesterone-estrogen-and-hashimotos-dr-felice-gersh/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Hashimoto’s at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

4 Sep 45min

196 Why Positive Thinking Can Backfire with Hashimoto’s with Anat Peri

196 Why Positive Thinking Can Backfire with Hashimoto’s with Anat Peri

In this powerful episode, Inna is joined by transformational leader and inner child expert Anat Peri to explore an unexpected twist in the Hashimoto’s healing journey. Together, they dive into the case of Jessica, who was doing all the “right” things, following the AIP diet, taking supplements, working on her mindset, but still felt exhausted and stuck. Her symptoms weren’t improving, and her doctor’s solution was to increase her medication yet again.The turning point came when she uncovered something deeper. Jessica was trying so hard to stay positive, think positive, do her affirmations because that is what she was told she should be doing. However by doing that, she was unintentionally overriding her true emotions and it made her feel way worse.Anat explains how this kind of forced positivity can be a detriment because it can actually create stress in the nervous system, keeping the body in a chronic state of fight, flight, or freeze. This episode unpacks how overriding your feelings can actually worsen autoimmune symptoms and why true healing starts with emotional safety.Anat also shares the science behind how the nervous system reacts faster than the conscious mind, how inner child work helps create safety, and why nervous system regulation must come before mindset work can truly be effective. From breathwork to sensation naming to reparenting tools, you’ll learn how to create space for your emotions and support your healing from the inside out.This episode is an essential listen for anyone who has tried it all and still feels like something is missing. It might not be about doing more. It might be about feeling more.For full show notes, please see:https://innatopiler.com/podcasts/positive-thinking-hashimotos-anat-peri/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Hashimoto’s at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

24 Juli 54min

195 The Surprising Empath–Thyroid Connection with Kristen Schwartz

195 The Surprising Empath–Thyroid Connection with Kristen Schwartz

If you have Hashimoto’s, there’s a very real chance you’re also an empath and you may not even realize it.This matters more than you think. Because when you’re highly sensitive and constantly absorbing everything around you (other people’s energy, emotions, even stress), your nervous system takes the hit. And when the nervous system is in overdrive, it becomes very hard to heal, no matter how clean your diet is or how many supplements you take.In this episode, Inna is joined by trauma-informed coach and empath expert Kristen Schwartz to talk about something that’s rarely discussed in the Hashimoto’s world: how being an unrecognized empath can be one of the biggest hidden blocks to healing. Kristen breaks down how fatigue, overstimulation, anxiety, heart palpitations, and even sleep issues can all trace back to nervous system dysregulation and how this shows up differently in sensitive people.You’ll learn how to tell if this is what’s really happening in your body, how to start regulating (without adding more to your to-do list), and how to gently reconnect to yourself without pressure or performance. Kristen shares simple but powerful shifts that help you reclaim your energy, feel safe in your body again, and finally get unstuck.If you've ever felt like you're doing all the right things but still feel wired, tired, or anxious, this conversation could be the missing link. You’ll walk away with a deeper understanding of what’s really going on under the surface and what to do about it.----------For full show notes, please see:https://innatopiler.com/podcasts/empath-thyroid-connection-kristen-schwartz/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Hashimoto’s at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

10 Juli 50min

194 Conflicting Hashimoto’s Advice: How To Find Your Path to Healing

194 Conflicting Hashimoto’s Advice: How To Find Your Path to Healing

When you’re living with Hashimoto’s,  it’s easy to end up overwhelmed, especially when you’re getting conflicting advice from different practitioners. In this episode, Inna shares a real-life case where a client was stuck in that very situation, caught between protocols and unsure how to move forward. What helped wasn’t more advice, instead it was learning to trust her own intuition.To explore this idea further, Inna is joined by Karly Ashworth, a transformational coach and intuitive guide who helps people reconnect to their inner voice and find clarity. Together, they talk about how tuning into your intuition can help you navigate confusing symptoms, make better health decisions, and even uncover emotional patterns that might be affecting your thyroid.They dive into what intuition really is (and why we all have it), how it relates to the throat chakra and the thyroid, and why emotional triggers such as indecision or self-doubt can sometimes do just as much damage as physical ones. Karly also shares practical ways to quiet the noise, get grounded, and start recognizing the signals your body is already sending you.Whether you’ve been second-guessing your health decisions or you’ve just felt out of touch with your body, this episode is a powerful reminder that sometimes, the answers you’re looking for aren’t out there but they’re already within.For full show notes, please see (TIM PLEASE ADD LINK)Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Hashimoto’s at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

26 Juni 50min

193 Root Canals, Cavities, and Hashimoto’s: What Your Dentist Isn’t Telling You with Dr. Michelle Jorgensen

193 Root Canals, Cavities, and Hashimoto’s: What Your Dentist Isn’t Telling You with Dr. Michelle Jorgensen

When a patient has tried every clean-eating plan, every supplement protocol, and every practitioner,  but is still exhausted, anxious, and foggy  it’s time to look where no one else has. In this episode, Inna teams up with functional dentist Dr. Michelle Jorgensen to explore a very overlooked trigger and aggravator for Hashimoto’s symptoms: your mouth.Through the case of “Cindy,” a Hashimoto’s patient who did everything right but still wasn’t getting better, Inna and Dr. Michelle reveal how hidden dental infections, past root canals, and even the materials used in old dental work can silently drive inflammation and autoimmune flares. What looks like “perfect” dental health on X-rays might actually be masking deep, ongoing issues that most conventional dentists never catch.Dr. Michelle brings her unique insight as a dentist-turned-health detective, showing how problems like cavitations, mixed metals, and even mouth breathing can create a ripple effect on the immune system, the microbiome, and the thyroid. She also explains how to safely investigate and address these issues  and why healing often requires asking the questions no one else is asking.This episode opens a powerful new conversation for anyone with Hashimoto’s who still doesn’t feel well despite doing “everything right” and exactly what you can do to explore what your mouth is trying to tell you.----------For full show notes, please see:https://innatopiler.com/podcasts/root-canals-cavities-hashimotos-dentist-dr-michelle-jorgensen/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Hashimoto’s at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

12 Juni 52min

192 The Emotional Root of Chronic Symptoms in Hashimoto’s with Lizzy Swick

192 The Emotional Root of Chronic Symptoms in Hashimoto’s with Lizzy Swick

If you’ve ever felt like you’ve tried everything…very diet, every supplement, every protocol, but your Hashimoto’s symptoms still aren’t budging, this episode might be the missing link. In this tender and deeply personal conversation, Inna sits down with her dear friend and colleague Lizzy Swick, RDN, to explore a part of healing that’s so often overlooked: the emotional and nervous system layer. Lizzy shares her own journey of chronic migraines, pain, and doing all the right things until she discovered that true progress began when she stopped doing more and started feeling more.Together, they unpack what it really means to feel safe in your body and how emotions, past experiences, and the way we push ourselves can quietly drive inflammation, fatigue, and even autoimmunity. You’ll hear practical tools like "rage on the page" journaling, embodiment meditation, and the internal shifts that helped Lizzy finally get relief after years of searching. It’s gentle, honest, and eye-opening in the most beautiful way.This conversation is one that Inna truly hopes you’ll take to heart. It’s not just about healing your thyroid, it’s about healing you. If you’ve been stuck, if nothing is working, or if you’ve ever wondered whether your emotions and nervous system might be part of the puzzle, this episode will feel like a breath of fresh air. Please listen, it might be the turning point you didn’t know you needed.----------For full show notes, please see https://innatopiler.com/podcasts/root-chronic-symptoms-hashimotos-lizzy-swick/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Hashimoto’s at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

29 Maj 50min

191 Hashimoto’s and the Hidden Growth You Might Not See Yet

191 Hashimoto’s and the Hidden Growth You Might Not See Yet

When you’re in the thick of it, whether it’s fatigue, brain fog, a flare, or something even bigger, it’s so easy to feel like you’re losing yourself. But what if something deeper is happening beneath the surface? In this heartfelt solo episode, Inna shares a powerful reframe that might just change how you see your Hashimoto’s journey… and your life.Drawing from her own healing path with Hashimoto’s and the ongoing challenges she’s facing with her son Jake’s autism and PANDAS diagnosis, Inna opens up about what it means to go through something and become someone in the process. She shares how surrender, patience, humor, and deep empathy have shaped her, not just as a mom, but as a woman and practitioner.This episode is an invitation to pause and reflect on your own journey, what it’s teaching you, how it’s changing you, and who you’re becoming through it all. If you’ve ever felt alone in your struggles or unsure of your path, this conversation will help you feel seen, grounded, and more hopeful.----------For full show notes, please see https://innatopiler.com/podcasts/hashimotos-hidden-growth/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Hashimoto’s at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

15 Maj 22min

190 The Hidden Factor Behind Brain Fog and Fatigue in Hashimoto’s with Inna Topiler

190 The Hidden Factor Behind Brain Fog and Fatigue in Hashimoto’s with Inna Topiler

There’s one hidden factor that could be draining your energy and clouding your brain, and most people with Hashimoto’s have no idea it’s happening.In this episode, Inna reveals the overlooked role that poor blood and lymph flow play in fatigue and brain fog, and very specific things that can make a big difference in how your brain functions and how your body feels.She walks you through the exact steps you can take right now to improve circulation, clear your head, and start feeling better with gentle, doable strategies that actually work for Hashimoto’s. Plus, she dives into the full picture of why energy gets blocked, including deeper layers like blood sugar, mitochondrial inflammation, adrenal rhythm, and nutrient deficiencies. It’s everything you need to understand why you’re still tired and what to do about it.If you’ve been doing everything “right” but still feel off, you need to hear this.----------For full show notes, please see https://innatopiler.com/podcasts/brain-fog-fatigue-hashimotos-inna-topiler/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Hashimoto’s at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

1 Maj 18min

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