035 The Case of Unpredictable Anxiety w/ Trudy Scott
Thyroid Mystery Solved: Hashimoto's and Hypothyroidism Revealed14 Nov 2019

035 The Case of Unpredictable Anxiety w/ Trudy Scott

The Case:

  • Lauren is 32 and has been dealing with anxiety most of her life
  • She noticed that her anxiety can be worse during stressful times and during the winter.
  • She was on anti-anxiety medication but they made her feel flat.
  • She tried meditation for anxiety but this wasn't enough and didn’t completely resolve the panic attacks.

The Investigation

Lauren’s situation is pretty common and I knew that we had to get to the root of the problem if we were going to help her deal with her anxiety. I suspected her neurotransmitters were part of the solution so that’s where I started investigating.

Trudy Scott is a certified nutritionist and food-mood expert. She’s the author of The Anti-anxiety Food Solution: How the Foods You Eat Can Help You Calm Your Anxious Mind, Improve Your Mood and End Cravings and is the host of The Anxiety Summit.

Neurotransmitters Role in Anxiety

While anxiety is seldom only caused by neurotransmitters, there are several that can play a role. In this week’s episode, and for Lauren’s case, we look at two neurotransmitters - serotonin and gaba - which are both proven to impact our ability to handle stress and deal with different types of anxiety.

Can Low Serotonin Causes Anxiety?

Most people understand the relationship between serotonin and depression but they don’t realize that it also impacts anxiety. Low serotonin results in a specific type of anxiety, according to Trudy. She explains that it is linked to anxiety that may present as negative self talk, low mood, lack of confidence and self-esteem. Low serotonin can also result in panic attacks, phobias, ruminating thoughts (where you replay past events or constantly re-processing things) obsessive behaviors or obsessive thinking (often lying awake at night thinking about things). Another tell tale sign of low-serotonin-anxiety is afternoon and evening cravings were the only way to calm the anxiety is with eating (fulfilling the craving). Because serotonin naturally slows down during the darker winter months, anxiety can be seasonal.

Low GABA Triggers Anxiety

Anxiety triggered by low GABA (Gamma-Aminobutyric Acid) presents differently than anxiety caused by low serotonin. Low GABA anxiety is physical. This might present as general stiffness and tension in the body. You may lay awake at night feeling physically tense which stops you from being able to sleep. Often, low GABA suffers will feel tension in the gut, they may even feel sick to their stomach. Unlike those with low-serotonin anxiety who may self-medicate with food, those with low-GABA anxiety are more likely to self-medicate with alcohol.

Diagnosing Neurotransmitter Triggered Anxiety

There are a few tests (like urinary neurotransmitter tests and platelet serotonin tests) that can determine serotonin or GABA levels that can help determine if this might be the root cause of the anxiety. However, Trudy prefers to use a questionnaire to pinpoint the symptoms and then do a trial. For this, she has patients rank specific anxieties and then gives them a small dose, sublingually, of either GABA or an amino acid that replicates serotonin. She then re-administers the questionnaire. If there is a significant drop in their anxiety response, then she proceeds with a treatment plan.

Treating Anxiety Caused by Low Serotonin

Instead of just replacing the serotonin with a supplement, Trudy likes to help the body relearn how to make its own. Each treatment is highly individualized but a common plan would include amino acids including 5HTP and Tryptophan. These amino acids are considered substrates or precursors to us for us to make serotonin. There are some other nutrients that are needed like zinc, vitamin B6, magnesium, that are all cofactors that, together with tryptophan and 5HTP, help us to make our own serotonin.This supplement protocol, should be done along with dietary and lifestyle changes. Whatever caused the serotonin to slow down in the first place needs to also be addressed. This may be things like a gluten sensitivity, dysbiosis, parasites, autoimmune disease (like Hashimoto’s), or chronic stress.

Treating Anxiety Caused by Low GABA

Again, the treatment needs to be individualized and go hand in hand with diet or lifestyle changes that relate back to the root cause of the lower GABA production. Trudy prefers to use sublingual GABA supplements because its faster and it also ensures that there aren’t any issues with digestion. In this episode, she also addresses the controversial theory that GABA can’t cross the blood/brain barrier. There are different GABA receptors in the body (including muscle and gut) which she outlines as part of the reason that she feels GABA can still be effective. GABA has other benefits such as supporting the endocrine system, pancreas, liver, and fluoride-induced hypothyroidism. There are also benefits for people with diabetes.

The Gut Connection to Anxiety

So many things that happen in the gut can cause reduced levels of serotonin and GABA. 95% of our serotonin originates in the gut, so that is the first place to look when trying to determine the root cause of low-serotonin anxiety. Studies have found that 5HTP can improve motility. Poor motility is often linked to gut issues like SIBO (Small Intestinal Bacterial Overgrowth) so an added benefit to treating low-serotonin is that it improves gut health, which we know in turn improves communication through the vagus nerve resulting in decreased depression and anxiety.

Additionally, studies have shown that lactobacillus rhamnosus probiotics not only affect GABA receptors, they also lowers cortisol. High levels of cortisol are often related to depression and anxiety. So, this probiotic is improving gut health and simultaneously altering GABA and cortisol levels.

Deficiencies Related to Anxiety

Trudy also tests patient levels of B12, methylmalonic acid, and homocysteine. These can often contribute to anxiety. Constipation may also indicate a B12 deficiency and, as mentioned above, can contribute to anxiety through poor gut health. This may be treated with a B12 supplement.

Cautions About Supplements and Anxiety

Each protocol is highly individualized because there may be other factors to consider. For example, if someone is on an antidepressant or anti-anxiety medication, natural treatments must be monitored carefully. Additionally, if someone has Lyme disease, an auto-immune disease or heavy metal toxicity, the protocol needs to be altered. Some do find that by getting to the root cause, dealing with it, and then retraining the body to produce adequate amounts of serotonin or GABA results in them being able to stop taking medication - but that would need to be determined by the individuals professional health team.

Mystery Solved

When we looked at Lauren’s symptoms in light of a potential neurotransmitter issues, they pointed directly to low serotonin. Here’s what she was experiencing:

  • Anxiety
  • Panic attacks or phobias
  • Feeling worried or fearful
  • Obsessive thoughts or behaviors
  • Perfectionism or being overly controlling

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197 What No One Told You About The Connection of Progesterone, Estrogen, and Hashimoto’s with Dr. Felice Gersh (Part 1)

197 What No One Told You About The Connection of Progesterone, Estrogen, and Hashimoto’s with Dr. Felice Gersh (Part 1)

In this episode of Thyroid Mystery Solved, Inna welcomes back the brilliant Dr. Felice Gersh for a conversation that takes Hashimoto’s and hormones to a whole new level. Together, they dive deep into the role of estrogen and progesterone in regulating the immune system, inflammation, and thyroid health. Most people have only heard the basics about these hormones, but as Dr. Gersh explains, the story goes far beyond reproduction. From Hashimoto’s flares that appear around menstrual cycles to the critical impact of hormones during perimenopause and menopause, this discussion unpacks what most doctors never tell their patients and you are going to be amazed!Dr. Gersh also shines a light on how misconceptions about hormones, especially progesterone, have shaped conventional medicine and why so many women are left without the support they truly need. This episode is part one of a two-part series, and it is filled with insights that will completely change the way you think about hormones and Hashimoto’s.----------For full show notes, please see https://innatopiler.com/podcasts/connection-progesterone-estrogen-and-hashimotos-dr-felice-gersh/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Hashimoto’s at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

4 Sep 45min

196 Why Positive Thinking Can Backfire with Hashimoto’s with Anat Peri

196 Why Positive Thinking Can Backfire with Hashimoto’s with Anat Peri

In this powerful episode, Inna is joined by transformational leader and inner child expert Anat Peri to explore an unexpected twist in the Hashimoto’s healing journey. Together, they dive into the case of Jessica, who was doing all the “right” things, following the AIP diet, taking supplements, working on her mindset, but still felt exhausted and stuck. Her symptoms weren’t improving, and her doctor’s solution was to increase her medication yet again.The turning point came when she uncovered something deeper. Jessica was trying so hard to stay positive, think positive, do her affirmations because that is what she was told she should be doing. However by doing that, she was unintentionally overriding her true emotions and it made her feel way worse.Anat explains how this kind of forced positivity can be a detriment because it can actually create stress in the nervous system, keeping the body in a chronic state of fight, flight, or freeze. This episode unpacks how overriding your feelings can actually worsen autoimmune symptoms and why true healing starts with emotional safety.Anat also shares the science behind how the nervous system reacts faster than the conscious mind, how inner child work helps create safety, and why nervous system regulation must come before mindset work can truly be effective. From breathwork to sensation naming to reparenting tools, you’ll learn how to create space for your emotions and support your healing from the inside out.This episode is an essential listen for anyone who has tried it all and still feels like something is missing. It might not be about doing more. It might be about feeling more.For full show notes, please see:https://innatopiler.com/podcasts/positive-thinking-hashimotos-anat-peri/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Hashimoto’s at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

24 Juli 54min

195 The Surprising Empath–Thyroid Connection with Kristen Schwartz

195 The Surprising Empath–Thyroid Connection with Kristen Schwartz

If you have Hashimoto’s, there’s a very real chance you’re also an empath and you may not even realize it.This matters more than you think. Because when you’re highly sensitive and constantly absorbing everything around you (other people’s energy, emotions, even stress), your nervous system takes the hit. And when the nervous system is in overdrive, it becomes very hard to heal, no matter how clean your diet is or how many supplements you take.In this episode, Inna is joined by trauma-informed coach and empath expert Kristen Schwartz to talk about something that’s rarely discussed in the Hashimoto’s world: how being an unrecognized empath can be one of the biggest hidden blocks to healing. Kristen breaks down how fatigue, overstimulation, anxiety, heart palpitations, and even sleep issues can all trace back to nervous system dysregulation and how this shows up differently in sensitive people.You’ll learn how to tell if this is what’s really happening in your body, how to start regulating (without adding more to your to-do list), and how to gently reconnect to yourself without pressure or performance. Kristen shares simple but powerful shifts that help you reclaim your energy, feel safe in your body again, and finally get unstuck.If you've ever felt like you're doing all the right things but still feel wired, tired, or anxious, this conversation could be the missing link. You’ll walk away with a deeper understanding of what’s really going on under the surface and what to do about it.----------For full show notes, please see:https://innatopiler.com/podcasts/empath-thyroid-connection-kristen-schwartz/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Hashimoto’s at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

10 Juli 50min

194 Conflicting Hashimoto’s Advice: How To Find Your Path to Healing

194 Conflicting Hashimoto’s Advice: How To Find Your Path to Healing

When you’re living with Hashimoto’s,  it’s easy to end up overwhelmed, especially when you’re getting conflicting advice from different practitioners. In this episode, Inna shares a real-life case where a client was stuck in that very situation, caught between protocols and unsure how to move forward. What helped wasn’t more advice, instead it was learning to trust her own intuition.To explore this idea further, Inna is joined by Karly Ashworth, a transformational coach and intuitive guide who helps people reconnect to their inner voice and find clarity. Together, they talk about how tuning into your intuition can help you navigate confusing symptoms, make better health decisions, and even uncover emotional patterns that might be affecting your thyroid.They dive into what intuition really is (and why we all have it), how it relates to the throat chakra and the thyroid, and why emotional triggers such as indecision or self-doubt can sometimes do just as much damage as physical ones. Karly also shares practical ways to quiet the noise, get grounded, and start recognizing the signals your body is already sending you.Whether you’ve been second-guessing your health decisions or you’ve just felt out of touch with your body, this episode is a powerful reminder that sometimes, the answers you’re looking for aren’t out there but they’re already within.For full show notes, please see (TIM PLEASE ADD LINK)Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Hashimoto’s at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

26 Juni 50min

193 Root Canals, Cavities, and Hashimoto’s: What Your Dentist Isn’t Telling You with Dr. Michelle Jorgensen

193 Root Canals, Cavities, and Hashimoto’s: What Your Dentist Isn’t Telling You with Dr. Michelle Jorgensen

When a patient has tried every clean-eating plan, every supplement protocol, and every practitioner,  but is still exhausted, anxious, and foggy  it’s time to look where no one else has. In this episode, Inna teams up with functional dentist Dr. Michelle Jorgensen to explore a very overlooked trigger and aggravator for Hashimoto’s symptoms: your mouth.Through the case of “Cindy,” a Hashimoto’s patient who did everything right but still wasn’t getting better, Inna and Dr. Michelle reveal how hidden dental infections, past root canals, and even the materials used in old dental work can silently drive inflammation and autoimmune flares. What looks like “perfect” dental health on X-rays might actually be masking deep, ongoing issues that most conventional dentists never catch.Dr. Michelle brings her unique insight as a dentist-turned-health detective, showing how problems like cavitations, mixed metals, and even mouth breathing can create a ripple effect on the immune system, the microbiome, and the thyroid. She also explains how to safely investigate and address these issues  and why healing often requires asking the questions no one else is asking.This episode opens a powerful new conversation for anyone with Hashimoto’s who still doesn’t feel well despite doing “everything right” and exactly what you can do to explore what your mouth is trying to tell you.----------For full show notes, please see:https://innatopiler.com/podcasts/root-canals-cavities-hashimotos-dentist-dr-michelle-jorgensen/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Hashimoto’s at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

12 Juni 52min

192 The Emotional Root of Chronic Symptoms in Hashimoto’s with Lizzy Swick

192 The Emotional Root of Chronic Symptoms in Hashimoto’s with Lizzy Swick

If you’ve ever felt like you’ve tried everything…very diet, every supplement, every protocol, but your Hashimoto’s symptoms still aren’t budging, this episode might be the missing link. In this tender and deeply personal conversation, Inna sits down with her dear friend and colleague Lizzy Swick, RDN, to explore a part of healing that’s so often overlooked: the emotional and nervous system layer. Lizzy shares her own journey of chronic migraines, pain, and doing all the right things until she discovered that true progress began when she stopped doing more and started feeling more.Together, they unpack what it really means to feel safe in your body and how emotions, past experiences, and the way we push ourselves can quietly drive inflammation, fatigue, and even autoimmunity. You’ll hear practical tools like "rage on the page" journaling, embodiment meditation, and the internal shifts that helped Lizzy finally get relief after years of searching. It’s gentle, honest, and eye-opening in the most beautiful way.This conversation is one that Inna truly hopes you’ll take to heart. It’s not just about healing your thyroid, it’s about healing you. If you’ve been stuck, if nothing is working, or if you’ve ever wondered whether your emotions and nervous system might be part of the puzzle, this episode will feel like a breath of fresh air. Please listen, it might be the turning point you didn’t know you needed.----------For full show notes, please see https://innatopiler.com/podcasts/root-chronic-symptoms-hashimotos-lizzy-swick/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Hashimoto’s at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

29 Maj 50min

191 Hashimoto’s and the Hidden Growth You Might Not See Yet

191 Hashimoto’s and the Hidden Growth You Might Not See Yet

When you’re in the thick of it, whether it’s fatigue, brain fog, a flare, or something even bigger, it’s so easy to feel like you’re losing yourself. But what if something deeper is happening beneath the surface? In this heartfelt solo episode, Inna shares a powerful reframe that might just change how you see your Hashimoto’s journey… and your life.Drawing from her own healing path with Hashimoto’s and the ongoing challenges she’s facing with her son Jake’s autism and PANDAS diagnosis, Inna opens up about what it means to go through something and become someone in the process. She shares how surrender, patience, humor, and deep empathy have shaped her, not just as a mom, but as a woman and practitioner.This episode is an invitation to pause and reflect on your own journey, what it’s teaching you, how it’s changing you, and who you’re becoming through it all. If you’ve ever felt alone in your struggles or unsure of your path, this conversation will help you feel seen, grounded, and more hopeful.----------For full show notes, please see https://innatopiler.com/podcasts/hashimotos-hidden-growth/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Hashimoto’s at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

15 Maj 22min

190 The Hidden Factor Behind Brain Fog and Fatigue in Hashimoto’s with Inna Topiler

190 The Hidden Factor Behind Brain Fog and Fatigue in Hashimoto’s with Inna Topiler

There’s one hidden factor that could be draining your energy and clouding your brain, and most people with Hashimoto’s have no idea it’s happening.In this episode, Inna reveals the overlooked role that poor blood and lymph flow play in fatigue and brain fog, and very specific things that can make a big difference in how your brain functions and how your body feels.She walks you through the exact steps you can take right now to improve circulation, clear your head, and start feeling better with gentle, doable strategies that actually work for Hashimoto’s. Plus, she dives into the full picture of why energy gets blocked, including deeper layers like blood sugar, mitochondrial inflammation, adrenal rhythm, and nutrient deficiencies. It’s everything you need to understand why you’re still tired and what to do about it.If you’ve been doing everything “right” but still feel off, you need to hear this.----------For full show notes, please see https://innatopiler.com/podcasts/brain-fog-fatigue-hashimotos-inna-topiler/Get ThyroLove - the first all in one bottle multi-nutrient comprehensive formula designed specifically for those with Hashimoto’s at ThyroLove.com - use code “Podcast” to get 10% off and free shipping For more information about everything Hashimoto’s please visit InnaTopiler.comIf you are struggling to lose weight with Hashimoto’s, Inna has a 10 day plan just for you at InnaTopiler.com/jumpstartIf you need help with fatigue or brain fog with Hashimoto’s, please check out Inna’s 9 Day Exhaustion Solution at innatopiler.com/energyIf you don’t yet know your thyroid type, please be sure you sign up for Inna’s next free training at InnaTopiler.com/zoomcall

1 Maj 18min

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