Dr Evelyn Cooper | Dr Candice Duncan – Improving Agriculture and Geoscience through Educational Initiatives

Research from Professor Germaine A. Hoston at the University of California, San Diego, reveals how traditional Chinese philosophical idealism influenced the development of Chinese Marxism. Her findings demonstrate that despite their rejection of China's feudal past, key Chinese Marxist theorists like Li Dazhao and Mao Zedong incorporated elements of Neo-Confucian idealism into their revolutionary philosophy. This "sinification" of Marxism drew particularly on concepts of consciousness, will, and the unity of knowledge and action from traditional Chinese thought, creating a uniquely Chinese revolutionary philosophy that challenged Soviet economic determinism.

6 Maj 9min

Sitting directly over a complex network of fault lines, Haiti is one of the most earthquake-prone nations on Earth. In 2021, the Nippes earthquake became the latest to devastate the country, and today, researchers are still piecing together the timeline of seismic events which unfolded during the earthquake. Through their research, Professor Jeremy Maurer and colleagues at Missouri University of Science and Technology have described how the Nippes earthquake originated, shifted, and ruptured a major fault line, triggering numerous ‘afterslip’ events in the following days.

1 Maj 6min

Research from Professors Tristan Nighswander and Ariel Roddy at Northern Arizona University examines the effects of pre-employment training on employment outcomes for previously incarcerated individuals through the lens of two economic theories. Their findings reveal that while training significantly improves employment outcomes for the general population, it shows no meaningful benefit for those with incarceration histories. Even more surprisingly, high-ability individuals (defined through scores on an aptitude test called the Armed Forces Qualification Test, or the AFQT) with past incarceration may actually experience negative employment effects. This highlights the complex challenges of societal re-entry.

30 Apr 11min

We can imagine our health as a jigsaw, with each individual piece representing a different aspect of our medical history. These pieces might include blood test results, X-ray images or the notes taken by a doctor as we describe our symptoms. These jigsaw pieces are ultimately recorded and stored in electronic health records (or EHRs). EHRs are a valuable resource, providing an overview of someone’s health and they could have the potential to allow clinicians and researchers to unlock new medical insights. However, there’s a fly in the ointment - not all the pieces in such records always fit together correctly, and they may not completely capture the required information. Some clinical event documentation may not be complete, others do not align with related pieces, and some events are even missing entirely. This data quality problem was tackled by Dr. Hanieh Razzaghi of the Children’s Hospital of Philadelphia, and her colleagues, in their innovative work on the PRESERVE study, a research project exploring chronic kidney disease in children (the PRESERVE study itself was led by Drs. Michelle Denburg and Christopher Forrest). Using EHRs from 15 different hospitals across the United States, the team aimed to understand how various treatments could potentially slow down chronic kidney disease progression. However, initially, they had to make sure that the data they were relying on were accurate, reliable, and suitable for the required complex analyses.

29 Apr 8min

Associate Professor Yassir Mahgoub and his team at Penn State University have uncovered an important link between melancholia – a severe form of depression that often doesn’t respond to treatment – and catatonia – a condition characterized by abnormal movements and associated with schizophrenia. The researchers analyzed case studies involving six patients who had been hospitalized for severe depression. All six patients experienced significant relief from their depressive symptoms by taking lorazepam – a drug typically used to treat catatonia. This discovery reveals a potential new avenue for treating severe, treatment-resistant depression.

25 Apr 8min

Our gut contains a sleepless army, creating a hostile environment for pathogens, and helping to fortify our body’s immune defences. It may surprise you to learn that this army isn’t even human in nature, but is bacterial. The trillions of bacteria that naturally live in our gut, known as the gut microbiota, form an important component of our overall immunity against infectious disease. While bacteria can also cause disease, beneficial bacteria naturally colonise available spaces in our body, such as the gut, and play a key role in our immunity and physiology. Research conducted by Prof. Nelson Gekara of Stockholm University in Sweden and colleagues has revealed that these microscopic organisms play a crucial role in protecting us from viral infections, even in organs that are unconnected to the gut. Their study, published in the journal Immunity, uncovers a fascinating link between the gut microbiota and our body's ability to fight viruses, offering new insights into immune function and the unintended consequences of antibiotic use.

24 Apr 10min

A recent paper from Professor William Gardner at Texas Tech University and Professor Kelly Davis McCauley at West Texas A&M University challenges a critique that characterized authentic leadership theory as “wrong” and "perilous." Their analysis demonstrates how misrepresentations of the theory can undermine valuable leadership approaches, while highlighting the empirical support and practical benefits of leaders striving for authenticity in organizational settings.

23 Apr 10min

Cancer is a daunting healthcare challenge, and is still affecting millions worldwide, despite the enormous research resources that have been directed at finding effective treatments over the past decades. Many anti-cancer treatments remain poorly specific for the tumours they are intended to treat, and often suffer from modest efficacy and serious off-target effects. Part of the problem is the inherent variability between many tumours and their resulting unpredictable responses to standard chemotherapy. However, the latest advancements in precision oncology may be the start of a new paradigm, potentially providing targeted therapeutic payloads that can successfully address the specific and unique issues underlying a given patient’s cancer. Researchers such as Prof. Diana Jaalouk and her colleagues at the American University of Beirut in Lebanon are pioneering innovative tools that are changing the way we understand and treat this complex disease. Two remarkable recent technologies, CRISPR-Cas9 and PROteolysis TArgeting Chimeras (or PROTACs for short), are at the forefront of this precision revolution. While distinct in their approach, these tools share a common goal: targeting cancer with precision and minimizing harm to healthy cells. Together, they are set to reshape the therapeutic landscape.

17 Apr 7min