157 | Elizabeth Strychalski on Synthetic Cells and the Rules of Biology

157 | Elizabeth Strychalski on Synthetic Cells and the Rules of Biology

Natural selection has done a pretty good job at creating a wide variety of living species, but we humans can't help but wonder whether we could do better. Using existing genomes as a starting point, biologists are getting increasingly skilled at designing organisms of our own imagination. But to do that, we need a better understanding of what different genes in our DNA actually do. Elizabeth Strychalski and collaborators recently announced the construction of a synthetic microbial organism that self-reproduces just like a normal unicellular creature. This work will help us understand the roles of genes in reproduction, one step on the road to making DNA molecules and artificial cells that will perform a variety of medical and biological tasks.

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Elizabeth Strychalski received her Ph.D. in physics from Cornell University. She is the founder and current leader of the Cellular Engineering Group at the National Institute of Standards and Technology. She serves on the steering group for the Build-A-Cell collaboration.


Avsnitt(416)

AMA | March 2026

AMA | March 2026

Welcome to the March 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patre...

2 Mars 3h 53min

345 | Adam Elga on Being Rational in a Very Large Universe

345 | Adam Elga on Being Rational in a Very Large Universe

Behaving rationally involves facing up to conditions of uncertainty; we never navigate the world with perfect confidence. Sometimes we are uncertain about the way the world is, but we can also be unce...

23 Feb 1h 34min

344 | Adam Gurri on Liberal Democracy and How to Fight For It

344 | Adam Gurri on Liberal Democracy and How to Fight For It

It's possible to look at the course of history over the past few centuries and discern a movement toward increasing democracy, freedom, and individual rights -- "liberalism," in the political-philosop...

16 Feb 1h 21min

343 | Tom Griffiths on The Laws of Thought

343 | Tom Griffiths on The Laws of Thought

For all that human beings spend a lot of their time thinking, it's far from obvious what that process actually entails. Part of it amounts to classical logical reasoning. But an even bigger part invol...

9 Feb 1h 19min

AMA | Feb 2026

AMA | Feb 2026

Welcome to the February 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pa...

2 Feb 3h 10min

342 | Rachell Powell on Evolutionary Convergence, Morality, and Mind

342 | Rachell Powell on Evolutionary Convergence, Morality, and Mind

Evolution with natural selection involves an intricate mix of the random and the driven. Mutations are essentially random, while selection pressures work to prefer certain outcomes over others. There ...

26 Jan 1h 37min

341 | Stewart Brand on Maintenance as an Organizing Principle

341 | Stewart Brand on Maintenance as an Organizing Principle

"Things fall apart; the centre cannot hold," wrote W.B. Yeats. I don't know about the centre, but the tendency of things to fall apart is pretty universal, ultimately due to the Second Law of Thermody...

19 Jan 1h 12min

340 | Rebecca Newberger Goldstein on What Matters and Why It Matters

340 | Rebecca Newberger Goldstein on What Matters and Why It Matters

At any given moment, an uncountable number of events are happening, but only some of them matter to us. What does it mean for something to matter, and more importantly, what does it mean for us to mat...

12 Jan 1h 18min

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