Ep. 482 How the Oral Microbiome Impacts Your Whole Body with Dr. Staci Whitman

I am happy to connect with Coach Bronson Dant today. He has spent over a decade guiding and training people in health and fitness. He discovered the benefits of a whole-food, animal-based ketogenic diet for optimizing metabolic health and performance, and wrote The Ultimate Ketogenic Fitness Book. In our discussion today, we dive into the powerful story of Coach Bronson’s pain-to-purpose journey. We explore the value of mindset and examine how age-related changes impact muscle, inflammation, and metabolic flexibility. He shares his three pillars of muscle health related to nutrient density, bioavailability, and satiety, and we examine the importance of sleep, the impact of extremes in exercise, and the value of stress management. We also unravel the complexities of weight loss resistance, and Coach Bronson discusses his research from the Journal of Nutrition Metabolism and Health Science, sharing his perspective on macros and functional movement in menopausal women. IN THIS EPISODE YOU WILL LEARN: Coach Bronson shares his three pillars for nutrition The limitations of basing nutrition on calories alone How the hormone piece impacts effective weight management How to avoid physical deterioration through fitness and nutrition Why Coach Bronson advocates for living life to the fullest and dying quickly How does muscle mass impact metabolic health? The importance of taking a balanced approach to weight loss How sleep aids muscle recovery and growth  Stress management, nutrition, and fitness for overall well-being How alcohol affects our health and fitness The benefits of combining functional movement training and proper nutrition for older adults  Connect with Cynthia Thurlow Follow on X, ⁠Instagram⁠ & ⁠LinkedIn⁠ Check out Cynthia’s ⁠website⁠ Submit your questions to support@cynthiathurlow.com Connect with Bronson Dant On his ⁠website⁠  ⁠YouTube⁠ and ⁠Instagram⁠ ⁠The Ultimate Ketogenic Fitness Bundle⁠

1 Sep 1h 4min

Today, I am thrilled to connect with Dr. Austin Perlmutter, a board-certified internal medicine physician, New York Times bestselling author, researcher, educator, podcaster, and entrepreneur. He is on a mission to help people get their brains unstuck for better mental and cognitive health.  In our conversation today, we explore brain inflammation and its connection to longevity, the differences between acute and chronic inflammation, the influence of environmental factors, and how exposure to negative news and biases can elevate stress and affect our brain health. We examine how consumer culture promotes stress and disconnection, and we unpack the immune-metabolic effects of estrogen and its impact on neuroplasticity and our ability to learn. We also focus on the role of nutrition and nutraceuticals, and we discuss the relationship between the brain, gut, and the vagus nerve. This discussion with Dr. Austin Perlmutter is rich and insightful, and I look forward to welcoming him back for further exploration into the science and research. IN THIS EPISODE, YOU WILL LEARN: Why brain inflammation becomes an issue for many women as they navigate middle age and beyond How inflammation leads to constant changes in our cognitive and mental state Various environmental factors and other inputs that could influence brain inflammation Some easy ways to positively impact your brain health and cognition How chronic stress affects the brain How the gut microbiome and the gut immune system influence cognitive and mental health The long-term health benefits of avoiding processed foods and following a Mediterranean diet  The importance of being conscientious and purposeful about the quality of the foods you eat Dr. Perlmutter shares easy and cost-effective ways to improve your cognitive, mental, and overall health Bio: Dr. Austin Perlmutter is a board-certified internal medicine physician, New York Times bestselling author, published researcher, and a leading expert on how lifestyle and environmental factors impact mental health. His mission is to help people reclaim their mental and physical health by addressing the biological basis of “stuckness” that disrupts brain function and emotional balance. He is a co-producer of the Alzheimer’s: The Science of Prevention series and the host of the Better Brain Blueprint series, where he provides actionable strategies to support brain resilience. Dr. Perlmutter currently serves as the Managing Director at Big Bold Health, a food-as-medicine company focused on helping people rejuvenate health through better immune function, where he has published a pioneering study exploring the effects of plant nutrients on human aging through epigenetics. Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Austin Perlmutter On his website On social media: @draustinperlmutter Find out more about the research on immuno-metabolism pathways  Big Bold Health on social media: @bigboldhealth

30 Aug 58min

We have the second episode in a series of conversations with Dr. Thomas Dayspring today.  The esteemed Dr. Dayspring is an expert on internal medicine and clinical lipidology. In this episode, we continue with our last conversation, diving into Lp(a) and the influences of gender, race, and menopause. We explain how estrogen is a PCSK9 inhibitor and explore the significance of brain health and risks for dementia. We tackle cholesterol synthesis and discuss the side effects of statins, clarifying who is most susceptible to their impact on the brain. We also examine the significance of the desmosterol biomarker, highlighting the level to aim for, especially when making decisions regarding cholesterol medications, and we answer one question from a listener.  You may want to listen to this insightful conversation with the renowned Dr. Dayspring more than once. He has graciously agreed to return and film additional episodes, where we will dive into more questions from listeners.  IN THIS EPISODE, YOU WILL LEARN: Why Lp(a) is like a wolf in sheep's clothing for many individuals How Lp(a) levels are higher in African Americans and women, especially after menopause  Dr. Dayspring highlights that Lp(a) particles are even more pro-inflammatory than LDL particles How PCSK9 inhibitors are the only drugs that significantly reduce Lp(a) Why do women have a higher risk of dementia than men? Dr. Dayspring explains ApoE as the key lipoprotein for brain cholesterol transport. How statins cross the blood-brain barrier to lower brain cholesterol Why desmosterol levels matter New therapies that can lower ApoB and Lp(a) Why imaging is essential for menopausal women with elevated ApoB and Lp(a) Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Thomas Dayspring On X (@Drlipid) On LinkedIn Journal Article: Atherosclerosis: Non-genetic influences on lipoprotein(a) concentrations  Journal of the American Heart Association: Trajectories of Blood Lipid Profiles in Midlife Women: Does Menopause Matter?

27 Aug 1h

We have another episode in our series of sponsored podcasts today, with brands I like, know, and trust. I am delighted to reconnect with Angelo Keely, the founder and CEO of Kion, a supplement company that focuses on helping people look good, feel young, and be strong. In our discussion today, Angelo explains essential aminos, highlighting their importance and clarifying how to differentiate between various protein powders and other forms of protein. We explore the significance of bioavailability, anabolic resistance, and changes in body composition, discussing how protein needs increase with age and how dieting and caloric restriction can augment our protein requirements. We also cover the results of intermittent fasting, examining how sleep, stress, and lifestyle requirements can change with menopause. I regularly take Kion essential amino acids. They have generously offered a discount for our community. Use the link in the show notes to get 20% off your next Kion purchase. IN THIS EPISODE, YOU WILL LEARN: The importance of eating sufficient protein as you age How various protein sources, such as animal protein, plant protein, whey protein, and essential amino acids, differ Strategies to buffer your protein intake and support your body as you navigate middle age and beyond Why Leucine is vital for muscle protein synthesis Why you should only source your amino acid supplements from trusted brands that follow the science How much protein do you need to maintain your body composition as you age? Why sleep is crucial for muscle protein synthesis How supplementing with essential amino acids helps you maintain your muscle mass throughout your life   The benefits of body scans for a better understanding of your body composition Connect with Cynthia Thurlow   Follow on X Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Angelo Keely Get a 20% discount on Kion products

25 Aug 1h 3min

I am deeply honored to reconnect with Dr. Thomas Dayspring, who joined me in 2024 for an immensely popular five-part series. Dr. Dayspring is certified in internal medicine and clinical lipidology. He is a distinguished fellow of both the American College of Physicians and the National Lipid Association.  Today, we have the first episode in a new series of conversations with Dr. Dayspring, in which he will share more of his perspective and answer more questions from listeners. In our discussion, we review the basics about cholesterol, triglycerides, and lipoproteins, exploring the factors that contribute to the development of cardiovascular disease, the significance of ApoB and Lp(a), and the risk factors for younger women. We also dive into the limitations of traditional allopathic medicines, and Dr. Dayspring shares his views on lipids, lipid changes in menopause, specific ways to address ApoB, some of the challenges associated with statin therapy, and more.  Dr. Dayspring brings a wealth of experience and expertise to this discussion, and you are sure to find this series as invaluable as the last. IN THIS EPISODE, YOU WILL LEARN: Dr. Dayspring revisits the differences between cholesterol, triglycerides, and lipoproteins What atherosclerosis is, and why it is concerning Dr. Dayspring explains the structure and function of lipoproteins The role of ApoB in lipoprotein particles and its significance in atherosclerosis Some of the risk factors for lipid abnormalities in younger women Lipid changes that occur as women transition from perimenopause to menopause  Dr. Dayspring shares his take on statin therapy Ways to address high ApoB Dr. Dayspring’s suggested goals for ApoB therapy Connect with Cynthia Thurlow   Follow on ⁠X⁠, ⁠Instagram⁠ & ⁠LinkedIn⁠ Check out Cynthia’s ⁠website⁠ Submit your questions to ⁠support@cynthiathurlow.com⁠ Connect with Dr. Thomas Dayspring On⁠ X⁠ (@Drlipid) On⁠ LinkedIn⁠ ⁠Journal Article: Atherosclerosis: Non-genetic influences on lipoprotein(a) concentrations⁠  ⁠Journal of the American Heart Association: Trajectories of Blood Lipid Profiles in Midlife Women: Does Menopause Matter?⁠

23 Aug 1h

I am honored to connect with Mike Sapiro today. He is an ordained Zen Buddhist monk, poet, clinical psychologist, psychedelic psychotherapist, author, meditation teacher, and researcher, in addition to being a transformational coach for world-class musicians, athletes, veterans, scientists, authors, and playwrights. In our conversation, Mike talks about truth medicine and explains how trauma is a disconnection from the present moment, clarifying how the nervous system responds to chronic stress or trauma, and how midlife transitions can reactivate unhealed wounds. We explore how culture, ancestry, parenting, and epigenetics shape conditioning, and examine the roles of ego, psychedelics, and surrender in the healing process. We also discuss what it means to lead with the heart, integrity, and humility, and tackle the emotional weight of regret, remorse, and shame. Mike also recommends some simple yet powerful daily practices to help us heal. This conversation with Mike Sapiro is truly invaluable. I loved his book, Truth Medicine, and I know the wisdom in both the book and this episode will resonate deeply with many of you. IN THIS EPISODE, YOU WILL LEARN: The healing benefits of framing trauma as a disconnection from the present moment Understanding and addressing the causes of undesirable behaviors, and addressing the hurt and conditioning that drive them How chronic stress and trauma impact the nervous system How societal pressures and constant connectivity contribute to stress and a sense of disconnection The value of psychedelics for accessing new perspectives and insights How midlife transitions can reactivate unhealed wounds The benefit of involving the heart, psyche, and cosmos in the therapeutic process Why trusting, letting go, and surrendering are essential for psychedelic therapy  How integrity and humility can lead to profound healing and transformation within the therapeutic process Mike shares some small, consistent actions that can help build trust and self-care  Bio: Michael Ryoshin Sapiro, PsyD, is an ordained Zen Buddhist monk and poet, clinical psychologist, psychedelic psychotherapist, author, meditation teacher, and researcher. He is also a transformational coach for world-class musicians, athletes, former special operations veterans, scientists, CEOs, authors, and playwrights.  Over the last two decades, he has served and reached thousands of people in a variety of settings: therapy, workshops, international retreats, hosting a nationally syndicated radio show called Radio Awakened, keynote addresses, and being featured on podcasts. In the last several years, his work has been featured on over 20 well-known podcasts, and he is a co-host for global mental health summits put on by Wisdom for Life, landing in over 70 countries and reaching hundreds of thousands of people. He is featured in a documentary by Brandow Kapelow called “An Act of Service” on ketamine treatment for first responders that was featured by The New York Times. He currently works extensively with first responders in therapy, offering ketamine-assisted psychotherapy, leading retreats, and running calls with them. He believes that unconditional love, speaking one’s truth, and authenticity are the medicines for good health and a thriving life. His work is dedicated to personal awakening for the sake of collective transformation.  Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Michael Sapiro On his website On Instagram Purchase a copy of Truth Medicine

20 Aug 54min

I am delighted to have the privilege of reconnecting with Dr. Deb Matthew today. She joined me once before in Episode 259. She is a distinguished best-selling author, international speaker, and dedicated educator known as the Happy Hormone Doctor.  Cardiovascular disease is the number one killer of women in the United States, causing one of every 3.2 deaths among women annually. In our conversation today, Dr. Matthew and I delve into the realm of cardiovascular disease, exploring the benefits of hormone replacement therapy, essential laboratory testing, medications, and the neurocognitive changes that occur during perimenopause and menopause. We also focus on lifestyle, gut testing, and the all-time favorite topic of weight loss resistance.  Stay tuned for today’s engaging, enriching, and enlightening discussion with Dr. Deb Matthew. IN THIS EPISODE YOU WILL LEARN: How HRT reduces the risk of cardiovascular disease  How long-term use of estrogen can reduce the risk of heart disease over time Why should you do a hormone panel before starting HRT? How cortisol levels impact cardiovascular health How the coronary calcium score helps to predict heart attack risk Cholesterol markers and their significance in cardiovascular risk assessment Managing cholesterol levels in perimenopausal women The importance of addressing underlying hormonal imbalances in women to mitigate cognitive decline and lipid disorders The connection between gut health and brain fog How women’s testosterone levels impact their cognition and motivation Hormone imbalance and weight loss resistance in women  Connect with Cynthia Thurlow Follow on ⁠Twitter⁠ ⁠Instagram⁠ ⁠LinkedIn⁠ Check out Cynthia’s ⁠website⁠. Submit your questions to ⁠support@cynthiathurlow.com⁠. Connect with Dr. Deb Matthew On her ⁠website⁠ ⁠Facebook⁠ ⁠Instagram⁠ Dr. Deb Mathew’s book ⁠This is Not Normal on Amazon⁠ or ⁠download the ebook⁠  Previous Episode featuring Dr. Matthew ⁠Ep. 295: HRT’s Impact on Women’s Health Through Time with Dr. Deb Matthew

18 Aug 56min

Today, I have the honor of reconnecting with Dr. Vonda Wright, a renowned expert in Aging and Longevity with over 20 years of experience in orthopedic surgery and sports medicine. She is also the host of the Hot for Your Health podcast.  In our discussion, we examine how mainstream news relies on sedentary science, highlighting the hallmarks of aging and the value of shifting mindsets around aging. We explore the foundational role of mitochondria in cellular health changes as we navigate the aging process, looking at satellite cells and the communication between muscle, bone, and adipose tissue. We also discuss the musculoskeletal syndrome in menopause, VO2 Max, and the science and lab testing that can help predict longevity and peak performance. This conversation with Dr. Vonda Wright is truly invaluable, and I highly recommend her book, Unbroken, as a powerful resource for understanding the transition from perimenopause to menopause. IN THIS EPISODE, YOU WILL LEARN: Vonda explains how mainstream news is based on sedentary science  How hormonal changes impact muscle quality during the perimenopause to menopause transition Why exercise is essential for rejuvenating muscle stem cells and maintaining muscle mass as we age  How satellite cells can lose their regenerative capacity through inactivity Why exercise is necessary for producing Klotho (the longevity protein)  How your muscles, bones, and fat are in constant communication The benefit of VO2 Max for understanding how your current level of fitness will project into the future The importance of knowing your longevity goals for creating a balanced fitness plan  Knowing the difference between being lean and being healthy Why muscle mass is crucial for your health and mobility The specialty labs Dr. Vonda uses in her practice Connect with Cynthia Thurlow   Follow on X Instagram LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Connect with Dr. Vonda Wright On her website  Instagram and YouTube Dr. Wright’s book, Unbreakable, will come out on the 26th of August. You can pre-order a copy and get your Unbreakable Data Assessment App here.

16 Aug 52min