Essentials: Effects of Fasting & Time Restricted Eating on Fat Loss & Health
Huberman Lab28 Aug 2025

Essentials: Effects of Fasting & Time Restricted Eating on Fat Loss & Health

In this Huberman Lab Essentials episode, I explore intermittent fasting and time-restricted eating, highlighting the positive benefits for weight loss, metabolism, organ health, circadian rhythms and cellular repair. I explain a practical framework for designing a time-restricted eating window that aligns with your lifestyle, exercise schedule and social schedule. I also cover what breaks a fast, how to support fasting with tools like salt intake and post-meal walks, and the use of fasting-related supplements, including berberine and metformin. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Carbon: https://joincarbon.com/huberman LMNT: https://drinklmnt.com/huberman Joovv: https://joovv.com/huberman Timestamps (00:00) Intermittent Fasting, Time-Restricted Eating (TRE) (00:50) Diet, Weight Loss, Calories & Hormones (05:50) Body’s Response to Eating vs Fasting, Fasting Duration (09:04) Sponsor: Carbon (10:50) Time-Restricted Feeding & Metabolic Benefits, Circadian Gene Rhythm (16:19) Optimal Meal Timing, Tool: Extend Sleep-Related Fasts (21:29) Sponsors: AG1 & LMNT (24:02) Eating Window Length, Tools: Adjusting TRE for Building Muscle, Regularity (26:55) Accelerate Transition to Fasting, Glucose Clearing, Tool: After-Meal Walk (28:36) Metformin, Berberine, Continuous Glucose Monitors; Cell Growth vs Repair, mTOR (31:46) Gut Microbiome; Transitioning to Intermittent Fasting & Individualization (34:03) Tool: 8-Hour Feeding Window & Weight Loss (35:25) Sponsor: Joovv (36:40) What Breaks a Fast?, Sugar; Tool: Using Salt to Support Fasting (39:42) Tool: Ideal Feeding Window Guidelines; Exercise & Social Considerations Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

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Science-Based Meditation Tools to Improve Your Brain & Health | Dr. Richard Davidson

Science-Based Meditation Tools to Improve Your Brain & Health | Dr. Richard Davidson

Dr. Richard Davidson, PhD, is a professor of psychology and psychiatry at the University of Wisconsin–Madison and a pioneer in the scientific study of meditation. We discuss how meditation changes you...

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Essentials: Benefits of Sauna & Deliberate Heat Exposure

Essentials: Benefits of Sauna & Deliberate Heat Exposure

In this Huberman Lab Essentials episode, I discuss the mechanisms through which deliberate heat exposure enhances both physical and mental health. I outline specific protocols for deliberate heat exp...

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Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex Marson

Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex Marson

Dr. Alex Marson, MD, PhD, is a Senior Investigator at the Gladstone Institutes and a professor of medicine at the University of California, San Francisco. We discuss the biology of the immune system a...

9 Mars 2h 27min

Essentials: The Biology of Taste Perception & Sugar Craving | Dr. Charles Zuker

Essentials: The Biology of Taste Perception & Sugar Craving | Dr. Charles Zuker

In this Huberman Lab Essentials episode, my guest is Dr. Charles Zuker, PhD, a professor of biochemistry, molecular biophysics and neuroscience at Columbia University and an Investigator with the Howa...

5 Mars 35min

Unlearn Negative Thoughts & Behaviors Patterns | Dr. Alok Kanojia

Unlearn Negative Thoughts & Behaviors Patterns | Dr. Alok Kanojia

Dr. Alok Kanojia, MD, MPH ("Dr. K"), is a Harvard-trained psychiatrist and expert in both Eastern and Western medicine to improve mental health. He explains tools for unlearning maladaptive thoughts a...

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Essentials: Using Light to Optimize Health

Essentials: Using Light to Optimize Health

In this Huberman Lab Essentials episode, I explore how different wavelengths of light affect the human body and how light exposure can improve sleep quality, mood and daytime alertness while supportin...

26 Feb 42min

Restore Youthfulness & Vitality to the Aging Brain & Body | Dr. Tony Wyss-Coray

Restore Youthfulness & Vitality to the Aging Brain & Body | Dr. Tony Wyss-Coray

Dr. Tony Wyss-Coray, PhD, is a professor of neurology at Stanford School of Medicine and Director of the Phil and Penny Knight Initiative for Brain Resilience who is discovering factors present in you...

23 Feb 1h 59min

Essentials: Optimize Your Exercise Program with Science-Based Tools | Jeff Cavaliere

Essentials: Optimize Your Exercise Program with Science-Based Tools | Jeff Cavaliere

In this Huberman Lab Essentials episode, my guest is Jeff Cavaliere, MSPT, CSCS, a physical therapist, strength coach and the founder of ATHLEAN-X, an online training platform. We explain the foundat...

19 Feb 40min

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