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In this episode, I describe the science of how and why pain arises in the body and brain, and how we can actively control our experience of pain. I discuss inflammation, stress, acupuncture, limb damage and Traumatic Brain Injury (TBI). I review protocols that leverage the lymphatic and nervous system to accelerate pain relief and healing in a variety of situations. Other topics discussed include how heat versus cold impacts neurons and wounds, red-light, sunlight, stem cells and more. Read the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://www.wakingup.com/huberman Timestamps 00:00:00 Introduction/Avenues for Support 00:00:31 Sponsors: AG1, LMNT & Waking Up 00:04:58 Deliberate Unlearning 00:06:43 Pain, Injury and Regeneration 00:09:17 A System of Touch (Somatosensation) 00:11:42 Pain and Injury are Dissociable 00:15:19 Objective versus Subjective Control of Experience 00:16:15 Plasticity of Perception 00:16:41 Lack of Pain Is Self-Destructive; So Is Excessive Pain 00:18:42 Homoculous, Ratonculous, Dogunculus 00:19:05 “Sensitivity” explained 00:21:30 Inflammation 00:22:24 Phantom Limb Pain 00:24:00 Top-down Relief of Pain by Vision 00:26:41 From Deaf to Hearing Sounds 00:28:10 Pain Is In The Mind & Body 00:29:44 Recovering Movement Faster After Injury 00:35:00 Don’t Over Compensate 00:37:34 Concussion, TBI & Brain Ageing 00:40:49 The Brain’s Sewage Treatment System: Glymphatic Clearance 00:43:05 Body Position & Angle During Sleep 00:44:30 Types of Exercise For Restoring & Maintaining Brain Health 00:47:33 Ambulance Cells in The Brain 00:49:20 True Pain Control by Belief and Context 00:51:45 Romantic Love and Pain 00:55:05 Dopaminergic Control of Pain 00:57:15 Acupuncture: Rigorous Scientific Assessment 01:07:32 Vagus Activation and Autonomic Control of Pain 01:08:30 Inflammation, Turmeric, Lead and DHT 01:11:40 Adrenalin: Wim Hof, Tummo, “Super-Oxygenation” Breathing 01:14:53 Protocols For Accelerating Tissue Repair & Managing Pain 01:17:55 Ice Is Not Always Nice (For Pain and Injury): Sludging, Fascia, Etc. 01:22:02 Chronic and/or Whole Body Pain; Red-Light Therapy, Sunlight 01:26:10 Glymphatics and Sleep 01:26:29 Stem Cells, Platelet Rich Plasma (PRP): Shams, Shoulds and Should Nots 01:31:38 Young Blood: Actual Science 01:35:44 Synthesis, Support & Resources Disclaimer & Disclosures