Episode 433: Our Most Important Conversations of 2025 with Dr. John Corboy, Dr. Mikael Simons, Dr. John DeLuca, and Dr. Stehen Krieger
RealTalk MS15 Joulu 2025

Episode 433: Our Most Important Conversations of 2025 with Dr. John Corboy, Dr. Mikael Simons, Dr. John DeLuca, and Dr. Stehen Krieger

As the year draws to a close, we wanted to share some of the most compelling conversations we've had over the past 12 months. And rather than make my own picks, we went through the hundreds of emails we've received over the past year from the RealTalk MS listener community to see which topics really connected with you.

In this week's episode, you'll hear from four of the top MS experts in the world discussing the subjects you've told me are most important to you.

First, we'll explore aging and MS with Dr. John Corboy, the principal investigator of the largest study designed to answer the question, "Once I turn 60, can I discontinue my disease-modifying therapies?"

We'll talk about remyelination with the winner of the 2025 Barancik Prize for Innovation in Multiple Sclerosis Research, Dr. Mikael Simons.

You'll hear our conversation with one of the world's top MS rehabilitation experts, Dr. John DeLuca, as we tackle one of the most disruptive MS symptoms -- fatigue.

And we'll wrap up this episode by talking with clinician-scientist Dr. Stephen Krieger about the confusion around trying to reconcile the idea of progression independent of relapse activity (PIRA) with a diagnosis of relapsing-remitting MS.

We have a lot to talk about! Are you ready for RealTalk MS??!

This Week: Our most important conversations of 2025 :22

Dr. John Corboy discusses aging and MS 1:07

Dr. Mikael Simons discusses remyelination 10:54

Dr. John DeLuca discusses MS-related fatigue 19:20

Dr. Stephen Krieger discusses how the current course descriptors for MS (relapsing-remitting, secondary progressive, primary progressive) may no longer be working for doctors or patients 26:11

Share this episode 42:10

Next week's episode 42:30

SHARE THIS EPISODE OF REALTALK MS

Just copy this link & paste it into your text or email: https://realtalkms.com/433

ADD YOUR VOICE TO THE CONVERSATION

I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts!

Email: jon@realtalkms.com
Phone: (310) 526-2283

And don't forget to join us in the RealTalk MS Facebook group!

LINKS

If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com

SIGN UP: Become an MS Activist
https://nationalmssociety.org/advocacy

JOIN: The RealTalk MS Facebook Group
https://facebook.com/groups/realtalkms

REVIEW: Give RealTalk MS a rating and review
http://www.realtalkms.com/review

Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com.

RealTalk MS Episode 433
Guests: Dr. John Corboy, Dr. Mikael Simons, Dr. John DeLuca, Dr. Stephen Krieger

Privacy Policy

Jaksot(502)

Episode 448: At the National MS Society's Public Policy Conference with David, Cliff, and Michelle

Episode 448: At the National MS Society's Public Policy Conference with David, Cliff, and Michelle

Last week, about 170 MS activists from across the country gathered in Washington, D.C. to participate in the National MS Society's Public Policy Conference. It's hard to come away from this event and ...

30 Maalis 31min

Episode 447: Walking with Many Sisters Toward a Cure with Brigitte Delaney

Episode 447: Walking with Many Sisters Toward a Cure with Brigitte Delaney

In 1988, there were just 42 Walk MS events, raising approximately $4 million. In 2025, there were 170 events across the country that raised over $30 million. As the largest private funder of MS resear...

23 Maalis 23min

Episode 446: MS Advocacy and the National MS Society's Public Policy Conference with Steffany Stern

Episode 446: MS Advocacy and the National MS Society's Public Policy Conference with Steffany Stern

175 MS activists are heading to Washington, D.C. next week for the National MS Society's Public Policy Conference. Their mission: to bring the concerns of the MS community directly to lawmakers on Cap...

16 Maalis 34min

Episode 445: It's MS Awareness Week with Kristine Werner Ozug and Kim, Kim, and Kim

Episode 445: It's MS Awareness Week with Kristine Werner Ozug and Kim, Kim, and Kim

It's MS Awareness Week, and this year we're diving into a theme that hits home for millions: Unseen MS. Multiple sclerosis is a master of disguise; it can be entirely invisible to the naked eye while ...

9 Maalis 40min

Episode 444: Treating MS with a GLP-1 with Dr. Ellen Mowry

Episode 444: Treating MS with a GLP-1 with Dr. Ellen Mowry

You know them by their trade names such as Ozempic, Wegovy, Mounjaro, and Zepbound. This class of medications is known as GLP-1 receptor agonists. And while they are best known for managing diabetes a...

2 Maalis 31min

Episode 443: The 2026 ACTRIMS Forum (Part 3) with Dr. Helen Tremlett, Dr. Ilana Katz Sand, and Kathy Smith

Episode 443: The 2026 ACTRIMS Forum (Part 3) with Dr. Helen Tremlett, Dr. Ilana Katz Sand, and Kathy Smith

Welcome back to the third and final part of our coverage of the 2026 ACTRIMS Forum. This week's episode bridges the gap between groundbreaking clinical research and the nuanced reality of living with ...

23 Helmi 35min

Episode 442: The 2026 ACTRIMS Forum (Part 2) with Dr. Jeffrey Cohen, Dr. Daniel Ontaneda, and Kristine Werner Ozug

Episode 442: The 2026 ACTRIMS Forum (Part 2) with Dr. Jeffrey Cohen, Dr. Daniel Ontaneda, and Kristine Werner Ozug

Welcome back to Part Two of our coverage of the 2026 ACTRIMS Forum. This week, we shift our focus to emerging therapies and clinical insights that are re-shaping the future of MS care. From the latest...

16 Helmi 44min

Episode 441: The 2026 ACTRIMS Forum with Dr. Manuel Friese, Dr. Amit Bar-Or, and Dr. Haritha Desu

Episode 441: The 2026 ACTRIMS Forum with Dr. Manuel Friese, Dr. Amit Bar-Or, and Dr. Haritha Desu

Last week, over 1,400 scientists and clinicians gathered in San Diego, California, at the 2026 Americas Committee for Treatment and Research in Multiple Sclerosis annual meeting, better known as the A...

9 Helmi 33min

Suosittua kategoriassa Terveys ja hyvinvointi

unicast
voi-hyvin-meditaatiot-2
psykopodiaa-podcast
vakeva-elama-viisaampi-mieli-vahvempi-keho
tiedenaiset-podcast
rss-pitaisko-erota
rss-narsisti
terapiassa
junnut-pelissa
puhu-muru
meditaatiot-suomeksi
aamukahvilla
rss-kuumilla-aalloilla
paritellen
rss-uplevel-by-sonja-hannus
rss-mighty-finland-podcast
rss-vapaudu-voimaasi
mielen-puolikkaat
rss-pt-paahtio