Biohacking News Weekly Update : 1383

Biohacking News Weekly Update : 1383

This episode covers:


• FDA Loosening Supplement Warning Labels

The FDA is considering a rule change that would allow supplement companies to include the DSHEA disclaimer only once per package rather than next to every claim. Dave explains why fewer visible warnings could make marketing look more like medical claims, and why biohackers should treat labels as advertising rather than evidence. He shares how to protect yourself now: add one variable at a time, run baseline labs, and rely on data instead of packaging.

Source: https://www.nbcnews.com/health/health-news/fda-supplements-warning-label-rule-change-rfk-jr-rcna249321

• Quantum Sensors for Early Heart Attack Detection

Mayo Clinic is testing a contactless heart-monitoring system called CardiAQ using quantum magnetic sensors and AI noise filtering. The device reads subtle electromagnetic signatures from the heart and compares them to invasive angiography. Dave breaks down why earlier detection of ischemia could shift heart care from reactive treatment to proactive screening — and why building baseline metrics like VO₂max, blood pressure and HRV today will pay off when next-gen diagnostics arrive.

Source: https://www.sandboxaq.com/press/sandboxaq-collaborates-with-mayo-clinic-on-novel-cardiac-diagnostics

• Sauna Detox for Microplastics

Emerging research shows that sweating meaningfully removes plastic-related chemicals like BPA and phthalate metabolites from the body, often more efficiently than blood or urine alone. Sauna use amplifies this effect by increasing circulation, mobilizing stored toxins from tissues, and accelerating sweat-based excretion. When you combine regular heat exposure with reduced environmental plastic contact, you create a powerful detox strategy that targets a chemical burden once thought unavoidable. Dave breaks down how sauna protocols can support toxin elimination, improve cardiovascular resilience, strengthen autonomic balance, and help counteract the metabolic and hormonal disruptions linked to microplastics in modern life.

Source: https://superage.com/can-you-sweat-out-microplastics-in-the-sauna/

• Psychedelics and Longevity Biomarkers

Bryan Johnson treated a guided psilocybin experience as a structured longevity experiment, collecting nearly 250 biomarkers including CGM, stress markers, HRV and Kernel brain imaging. The experiment revealed a surprising metabolic change: mean glucose dropped 8 percent, variability fell 11 percent, and estimated HbA1c moved from 4.7 to 4.4 — similar to months of metformin but after a single session. Dave explores the emerging idea that neuroplastic events might influence glucose regulation through brain-pancreas signaling, while emphasizing the need for supervised, legal use and proper clinical trials.

Source: https://www.businessinsider.com/bryan-johnson-trip-on-mushrooms-five-hours-live-2025-12


• A Mitochondrial Protein that Extends Mouse Lifespan

Researchers boosted the mitochondrial protein COX7RP and extended mouse lifespan by ~6.6 percent while improving insulin sensitivity, lipid handling, endurance and liver fat metabolism. COX7RP supports formation of mitochondrial “supercomplexes,” improving respiratory efficiency and ATP generation. Dave explains how this reinforces lifestyle levers — strength training, aerobic capacity, stabilizing blood sugar — as tools that likely preserve supercomplex architecture and mitochondrial resilience.

Source: https://www.eurekalert.org/news-releases/1109082


All source links provided for direct access to the original research and reporting.


This episode is designed for biohackers, longevity seekers and high-performance listeners who want practical strategies rooted in cutting-edge science. Dave Asprey translates emerging research into actionable upgrades for your biology — from metabolism and mitochondria to nervous system health, detox, and prevention.


New episodes every Tuesday, Thursday, Friday, and Sunday.


Keywords: FDA supplement rule change, supplement warning labels, DSHEA disclaimer removal, supplement regulation risks, quantum cardiac scanner, Mayo Clinic heart attack detection, AI heart monitoring, early ischemia detection technology, sauna detox evidence, sweating out toxins research, BPA phthalate sweat studies, microplastics sauna myth, Bryan Johnson psilocybin experiment, psychedelic longevity research, psychedelic metabolic reset, glucose control psychedelics, HbA1c psilocybin results, continuous glucose monitor insights, mitochondria lifespan research, COX7RP protein aging study, mitochondrial supercomplex benefits, ATP energy output aging, metabolic flexibility longevity, biohacking news update, anti-aging science breakthroughs, evidence-based longevity tools, biological age biomarkers


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• 40 Years of Zen: https://40yearsofzen.com

Timestamps:

0:00 - Intro

0:18 - Story 1: FDA Supplement Label Changes

1:43 - Story 2: CardiAQ Heart Scanner

2:59 - Story 3: Saunas and Microplastics

4:58 - Story 4: Psychedelics and Blood Sugar

8:22 - Story 5: Mitochondrial Longevity Research

10:29 - Weekly Wrap-Up

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Jaksot(1452)

#69 Clearing Up Cholesterol with Jimmy Moore

#69 Clearing Up Cholesterol with Jimmy Moore

What if everything you thought you knew about cholesterol was wrong? In this episode of Bulletproof Radio cholesterol expert Jimmy Moore about how we’re being lied to about our cholesterol health. We discuss triglycerides and lab results and reveal a wealth of information on the basics of cholesterol. You’ll learn the difference between LDL and HDL, why you don’t have to be fat to have bad heart health, and why low cholesterol is bad for baby making! And that’s just the tip of the iceberg. Enjoy! In January 2004, Jimmy Moore made a decision to get rid of the weight that was literally killing him. At 32 years of age and 410 pounds, the time had come for a radical change of lifestyle. A year later, he had shed 180 pounds, shrunk his waist by 20 inches, and dropped his shirt size from 5XL to XL. He is regarded as a fan of low carbohydrate diets and eating plans and promotes them through his blog, books, YouTube videos and podcasts. He currently resides in Spartanburg, South Carolina. Moore's latest book Cholesterol Clarity is a joint venture with Dr. Eric C. Westman. This book lays out in plain language what the numbers in a cholesterol test mean, and what can be done about them. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

25 Loka 201356min

#67 For the Love of Fermentation with Jill Ciciarelli

#67 For the Love of Fermentation with Jill Ciciarelli

Fermenting phenomenon Jill Ciciarelli is on the show to talk about her healthy hobby turned full-time passion, food fermentation. It’s a discerning topic amongst Bulletproof Radio listeners and enquiring minds want to know: Is fermenting optimal or not? You’ll hear Jill and Dave share their personal experiences with eating fermented foods, how it improves Jill’s life, and why Dave’s still a bit skeptical. Jill Ciciarelli is the author of Fermented: A Four Season Approach to Paleo Probiotic Foods and founder of the health blog First Comes Health. She graduated from the Institute for Integrative Nutrition as a holistic health coach and is certified by the American Association for Drugless Practitioners. Ciciarelli lives in Pennsylvania with her husband and a cat named Quincy. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

17 Loka 201342min

#66 “The Calorie Myth” with Jonathan Bailor

#66 “The Calorie Myth” with Jonathan Bailor

Millions of enquiring minds want to know: Calories, do they count or not? What if everything you were taught about eating, exercise, weight loss, and health could be proven wrong? On this episode you’ll hear Jonathan Bailor make a pretty sane argument for no more calorie counting and how doing so may actually be bad for your health! Learn how to eat more to weigh less, why you’ll want to ignore that number on the treadmill, and how not to be a slave to willpower. There’s a lot going on in this show! Collaborating with top scientists for over 10 years, analyzing over 1,300 studies, and garnering endorsements by top doctors from Harvard Medical School, Johns Hopkins, Yale, and UCLA, Jonathan Bailor is a nutrition and exercise expert and  former personal trainer who specializes in using high-quality food and exercise to simplify wellness. He has registered over 25 patents and authored the revolutionary upcoming book “The Calorie Myth.”   Bailor serves as a Senior Program Manager at Microsoft, hosts a popular syndicated wellness radio show, blogs on The Huffington Post, and consults for organizations around the world. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

15 Loka 201345min

#65 The Paleo Manifesto with John Durant

#65 The Paleo Manifesto with John Durant

Author of “The Paleo Manifesto” and professional caveman, John Durant, came on Bulletproof Radio to chat about primitive living in an urban jungle. In this fun and down to earth episode you’ll hear John and I talk about Paleo being a biohack and cricket-based protein! Whether you live in a cave now or just plan on retiring in one, there’s something in this show for everyone. John Durant is an author and health entrepreneur. He recently released his first book – The Paleo Manifesto: Ancient Wisdom for Lifelong Health – in which he advocates using evolutionary principles to combat the global epidemic of obesity, diabetes, and other chronic health conditions. He studied evolutionary psychology at Harvard before moving to New York City and becoming a “professional caveman”: running barefoot through Central Park, mimicking a hunter-gatherer diet, experimenting with intermittent fasting, and doing polar bear swims in the Atlantic. John has been featured in the New York Times, and interviewed on The Colbert Report and NPR Morning Edition. He keeps a freezer chest full of organ meats in the bedroom of his Manhattan apartment, and he is fully aware of how strange that is.     See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

10 Loka 201351min

#64 Grass Fed Beef from the Mountains of Idaho, with Glenn Elzinga from Alderspring Ranch

#64 Grass Fed Beef from the Mountains of Idaho, with Glenn Elzinga from Alderspring Ranch

Alderspring Ranch produces some of the best tasting and highest quality grass fed beef in North America. Glenn Elzinga, expert organic rancher and owner of Alderspring Ranch, shares what goes into creating Bulletproof approved beef and why it’. For over 20 years Glenn and Caryl Elzinga have worked hard and stayed true to the land and the cattle that roam on it. It’s a family ranch with a ton of heart and in this episode you will hear Glenn and I really geek out about beef. You will learn about the roots of Alderspring, why it’s so important not to micro-manage roaming cattle, how eating grass fed beef makes you more Bulletproof, and a lot more! Alderspring Ranch is a real place, a family ranch. Glenn and Caryl Elzinga have grown grass fed and finished beef in Idaho’s Rocky Mountains for over 20 years. It is in the wild and pristine setting of Idaho’s high Pahsimeroi Valley that they found the ideal place to raise their certified organic Angus beef.  In addition, Glenn’s background in forest ecology and Caryl’s as a PhD in plant ecology specifically equipped them to manage their landscape-level ranch comprised of over 70 square miles of high elevation wildlands- one of the largest certified organic ranches in the U.S They are experts at producing top quality cuts of beef for the discerning public. They are the opposite of a corporate outfit or a front through which to funnel odd cattle. Their passion is to grow the best beef you’ve ever had, and do it in a way that benefits all parts of an agricultural system, including the consumer, the land, the community, the cattle, and family. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

8 Loka 201358min

#63 Q&A: Heart Rate Variability, Food Sensitivities, and Charcoal

#63 Q&A: Heart Rate Variability, Food Sensitivities, and Charcoal

Being Bulletproof is about asking questions and getting answers. Take that suspicious spot on your calf, for example. Have you ever wondered what the heck it is? Have you ever questioned how marijuana can have an effect on heart rate variability? Each month, I record a special podcast to answer questions from the Bulletproof community. We pick the best questions that come from emails, Facebook, Twitter, the Bulletproof Forum, and the blog’s comment section. In this show you’ll gain access to a wealth of information that I hope will empower you on the way to living a more optimal life. Please enjoy! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Loka 201353min

#62 The New “Naked Calories” & Micronutrient, with Mira and Jayson Calton

#62 The New “Naked Calories” & Micronutrient, with Mira and Jayson Calton

Forget everything you thought you knew about micronutrients! Mira and Jayson Calton are back on the show to tell you the importance of micronutrients and discuss the new and improved “Naked Science.” You will hear about the dangers of micronutrient defficiency, the ABCs of optimal supplementation, and the importance of taking a properly formulated multi-vitamin. Did you know that in order to become micronutrient sufficient you would need to eat 27,575 calories a day of the standard American diet? Pretty crazy, right? The Calton’s have certainly done their research and this is definitely a podcast you don’t want to miss! Mira and Jayson Calton are among the world's leading experts on the topics of weight management, lifestyle medicine and micronutrient deficiency. In 2005 the Caltons’ lead a 100-country, 7 continent, 6-year global expedition to explore the dietary and lifestyle habits of people around the world– which also resulted in reversing Mira's advanced osteoporosis. The Caltons are columnists for First for Women magazine and Livestrong.com, and contribute regularly to media sources such as “Fox and Friends,” “Happening Now,” Headline News, NBC, ABC, AOL Travel, Prevention, Shape and more. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

1 Loka 201355min

#61 Gluten Sensitivity, Celiacs & Bulletproofing Your Gut, with Dr. Tom O'Bryan

#61 Gluten Sensitivity, Celiacs & Bulletproofing Your Gut, with Dr. Tom O'Bryan

Have you heard? Gluten is harmful, but do you know why? Dr. Tom O’Bryan explains away dietary gluten, how it is detrimental to your health, and why it keeps you from being optimal – in a big way! He talks about his 30 years of experience in researching Celiac disease and gluten sensitivity and how you can drastically increase the quality of your life by getting rid of gluten in your diet. We also talk about the number one supplement he recommends to Bulletproof your gut, how gluten is like morphine, and if there are such a thing as “good” grains.  If you want to understand gluten in a way you never have before and learn how it affects your body, this episode   is for you! Dr. Tom O’Bryan is a nationally recognized speaker, workshop leader, healer, and researcher specializing in Celiac disease & gluten intolerance. He is a highly esteemed clinician in treating chronic disease and metabolic disorders from a Functional Medicine perspective. Dr. O’Bryan is the Sherlock Holmes for chronic disease & metabolic disorders, a triathalete, and a second-degree black belt in Aikido. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

24 Syys 201352min

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