Biohacking News Weekly Update : 1383

Biohacking News Weekly Update : 1383

This episode covers:


• FDA Loosening Supplement Warning Labels

The FDA is considering a rule change that would allow supplement companies to include the DSHEA disclaimer only once per package rather than next to every claim. Dave explains why fewer visible warnings could make marketing look more like medical claims, and why biohackers should treat labels as advertising rather than evidence. He shares how to protect yourself now: add one variable at a time, run baseline labs, and rely on data instead of packaging.

Source: https://www.nbcnews.com/health/health-news/fda-supplements-warning-label-rule-change-rfk-jr-rcna249321

• Quantum Sensors for Early Heart Attack Detection

Mayo Clinic is testing a contactless heart-monitoring system called CardiAQ using quantum magnetic sensors and AI noise filtering. The device reads subtle electromagnetic signatures from the heart and compares them to invasive angiography. Dave breaks down why earlier detection of ischemia could shift heart care from reactive treatment to proactive screening — and why building baseline metrics like VO₂max, blood pressure and HRV today will pay off when next-gen diagnostics arrive.

Source: https://www.sandboxaq.com/press/sandboxaq-collaborates-with-mayo-clinic-on-novel-cardiac-diagnostics

• Sauna Detox for Microplastics

Emerging research shows that sweating meaningfully removes plastic-related chemicals like BPA and phthalate metabolites from the body, often more efficiently than blood or urine alone. Sauna use amplifies this effect by increasing circulation, mobilizing stored toxins from tissues, and accelerating sweat-based excretion. When you combine regular heat exposure with reduced environmental plastic contact, you create a powerful detox strategy that targets a chemical burden once thought unavoidable. Dave breaks down how sauna protocols can support toxin elimination, improve cardiovascular resilience, strengthen autonomic balance, and help counteract the metabolic and hormonal disruptions linked to microplastics in modern life.

Source: https://superage.com/can-you-sweat-out-microplastics-in-the-sauna/

• Psychedelics and Longevity Biomarkers

Bryan Johnson treated a guided psilocybin experience as a structured longevity experiment, collecting nearly 250 biomarkers including CGM, stress markers, HRV and Kernel brain imaging. The experiment revealed a surprising metabolic change: mean glucose dropped 8 percent, variability fell 11 percent, and estimated HbA1c moved from 4.7 to 4.4 — similar to months of metformin but after a single session. Dave explores the emerging idea that neuroplastic events might influence glucose regulation through brain-pancreas signaling, while emphasizing the need for supervised, legal use and proper clinical trials.

Source: https://www.businessinsider.com/bryan-johnson-trip-on-mushrooms-five-hours-live-2025-12


• A Mitochondrial Protein that Extends Mouse Lifespan

Researchers boosted the mitochondrial protein COX7RP and extended mouse lifespan by ~6.6 percent while improving insulin sensitivity, lipid handling, endurance and liver fat metabolism. COX7RP supports formation of mitochondrial “supercomplexes,” improving respiratory efficiency and ATP generation. Dave explains how this reinforces lifestyle levers — strength training, aerobic capacity, stabilizing blood sugar — as tools that likely preserve supercomplex architecture and mitochondrial resilience.

Source: https://www.eurekalert.org/news-releases/1109082


All source links provided for direct access to the original research and reporting.


This episode is designed for biohackers, longevity seekers and high-performance listeners who want practical strategies rooted in cutting-edge science. Dave Asprey translates emerging research into actionable upgrades for your biology — from metabolism and mitochondria to nervous system health, detox, and prevention.


New episodes every Tuesday, Thursday, Friday, and Sunday.


Keywords: FDA supplement rule change, supplement warning labels, DSHEA disclaimer removal, supplement regulation risks, quantum cardiac scanner, Mayo Clinic heart attack detection, AI heart monitoring, early ischemia detection technology, sauna detox evidence, sweating out toxins research, BPA phthalate sweat studies, microplastics sauna myth, Bryan Johnson psilocybin experiment, psychedelic longevity research, psychedelic metabolic reset, glucose control psychedelics, HbA1c psilocybin results, continuous glucose monitor insights, mitochondria lifespan research, COX7RP protein aging study, mitochondrial supercomplex benefits, ATP energy output aging, metabolic flexibility longevity, biohacking news update, anti-aging science breakthroughs, evidence-based longevity tools, biological age biomarkers


Thank you to our sponsors!

-BEYOND Conference 2026 | Register now at https://beyondconference.com/

-BodyGuardz | Visit https://www.bodyguardz.com/ and use code DAVE for 25% off.


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• Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome

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• Dave Asprey’s BEYOND Conference: https://beyondconference.com

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com

Timestamps:

0:00 - Intro

0:18 - Story 1: FDA Supplement Label Changes

1:43 - Story 2: CardiAQ Heart Scanner

2:59 - Story 3: Saunas and Microplastics

4:58 - Story 4: Psychedelics and Blood Sugar

8:22 - Story 5: Mitochondrial Longevity Research

10:29 - Weekly Wrap-Up

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Jaksot(1456)

Upgrade Your Keto Thinking – Steven Gundry, M.D. – Best of 2022

Upgrade Your Keto Thinking – Steven Gundry, M.D. – Best of 2022

IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™…… Steven Gundry, M.D., explains that ketones aren’t the fat-burning molecules you think they are. Ketones actually work to enhance health, weight loss, and longevity by acting as signaling molecules that stimulate your mitochondria. A cellular process known as “mitochondrial uncoupling” happens. He debunks common myths about keto in his newest book, “Unlocking the Keto Code: The Revolutionary New Science of Keto That Offers More Benefits Without Deprivation,” and shares eight “keys” that unlock the keto code: Intermittent fasting or time-controlled eating PolyphenolsDietary fiber Fermented foods PolyaminesCold temperaturesHot temperaturesRed light therapyUpgrading your nutrition with keto gets even simpler in this conversation that gives you real food examples of how to ignite your mitochondrial uncoupling process without a monotonous, limiting, high-fat diet.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Get 30% off products at https://gundrymd.com. Use code DAVE30 at checkout.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Clean up Zombie Cells with Senolytics: https://neurohacker.com/dave, use code Asprey15 to save 15%Cooler Temps for Deeper Sleep: https://www.chilisleep.com/, use code HUMANUPGRADE20 to save 20% on the Dock Pro Sleep System. Learn more: Upgrade Spotlight: Improve Your Sleep With a Cooler Body Temp – ChiliSleep – #923Business Growth With SEO: https://www.stephanspencer.com, get a FREE consultationSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

28 Joulu 20221h 29min

Upgrade Your Eyesight – Claudia Muehlenweg – Best of 2022

Upgrade Your Eyesight – Claudia Muehlenweg – Best of 2022

IN THIS “BEST OF” EPISODE OF THE HUMAN UPGRADE™… natural vision expert Claudia Muehlenweg explains how you can take better care of your eyes and improve your vision. Her work is based in the Bates Method. She focuses on finding the root cause of blurry vision instead of using symptomatic treatments like glasses, contacts or surgery that actually can make eyesight worse in the long term.For nearly 15 years, Claudia’s taught eyesight improvement for presbyopia, myopia, astigmatism, hyperopia, strabismus, convergence insufficiency, and eye diseases such as cataracts, macular degeneration and glaucoma. She also helps people restore clarity after corrective surgeries like LASIK have worn off. Claudia starts with root causes in your body, including nervous system regulation. She then brings in bodywork, breathwork, rest, light and movement healing methods. Listen on to get practical solutions and essential Dos and Don’ts for good eyesight.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!A Pre-Alcohol Probiotic to Offset a Rough Morning After: https://zbiotics.com/dave, use code DAVE to save 15% off your first order. Learn more: The Bacteria That Lets You Drink Alcohol Again – Zack Abbott, Ph.D. – #1000Biostack for High Performance: https://vatellia.com, use code DAVE2022 to save 10% or subscribe and save 15% + receive a free bottle of Kale BusterSleep Better on Natural Memory Foam: https://myessentia.com/daveasprey, use code DAVE to get an extra $100 off an Essentia mattress purchase on top of Essentia’s Holiday 25% off sale. Through Dec. 31, 2022, only. Learn more: Mattress Smarts 101 for High-Performance Sleep – Jack Dell’Accio – #875See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

23 Joulu 20221h 22min

Hacking Injury Healing from the Inside Out – Interventions With Dave – Rachelle Copeland : 1006

Hacking Injury Healing from the Inside Out – Interventions With Dave – Rachelle Copeland : 1006

In this Episode of The Human Upgrade™… Dave talks with Rachelle Copeland about putting her energy into healing facial injuries and building new tissues—starting with the central nervous system. Rachelle experienced an accident that injured her face, teeth, nerves and jaw. She wants to heal quickly and avoid scarring and long-term damage while also managing the accompanying emotional trauma.This intervention looks at ways to heal and recover both internally and externally, covering suggestions such as: EMDR, Tapping, EFT for physical and emotional trauma (What Is EMDR and How Does It Work?, Nick Ortner: The Tapping Solution for Pain Relief – #219, Tap into Tapping: The EFT Episode – Dawson Church # 474)Jaw misalignment (Dr. Dwight Jennings: TMJ, Jaw Pain, & Substance P – #179)Vagal nerve (Stephen Porges: The Polyvagal Theory & The Vagal Nerve – #264, The Nervous System Circuitry of Safety, Sound & Gratitude – Stephen Porges #573)Hyperbaric therapyCraniosacral workInflammationOral and topical cayenneRed and infrared, LED or laser light therapy Ozone therapySupplements to support healingEnzymesIf you’re recovering from injury, take a listen to this episode for tips and resources on how to heal.Note: The "Interventions With Dave” recommendations are designed to help you upgrade yourself and your biology so you can perform better at everything you do. They are not, however, a substitute for advice or treatment by a trained medical professional that may be needed for specific health conditions, illness or injury.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Vascular System Protection https://calroy.com/dave, save on a 3-pack to protect your blood vessels from vulnerable plaqueGet Fit in Five Minutes: https://www.carolbike.com, use code HumanUpgrade to get 2 years of free membership (a total savings of $360) on the CAROL Bike 2.0 and a 100-day home trial. 9th Annual Biohacking Conference: Come join like-minded people June 22-24 in Orlando, Florida, for three days of awesome! You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life.https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

21 Joulu 202228min

How Your Biomes Drive Custom Food & Supplement Solutions – Naveen Jain : 1005

How Your Biomes Drive Custom Food & Supplement Solutions – Naveen Jain : 1005

Viome sponsored this episode.IN THIS EPISODE OF THE HUMAN UPGRADE™… entrepreneur and philanthropist Naveen Jain joins the show in person at the Beverly Hilton to talk about new developments in the human biome—particularly the oral microbiome. Turns out, there may be more density in your gut microbiome, but there’s more diversity in your oral microbiome.Naveen’s company, Viome, built an AI-driven platform that analyzes the interaction between food, your body’s biomes, and your cells from at-home tests. Your results are used to develop precise ways of eating and taking supplements that prevent and can even help reverse chronic disease. They’ve so far collected 425,000 samples showing 600 trillion data points.The newest Viome test kit takes a look at your oral health. Viome prepares custom supplements, probiotics and prebiotics with the exact ingredients in the exact dosages you need based on your personal test results. This customization is important because supplements are not universally healthy, more isn’t better, and consuming nutrients and biotics you don’t need can actually do more harm than good. Custom formulations work with and for your own physiology.Viome testing also helps you see your personal health trends over time. Your tests could show different results at six months or a year. Then, your supplements would be adjusted to your changing physiology. Check out Viome’s at-home test kits:Oral Health Intelligence: coming soon!Full Body Intelligence (gut, cellular, oral health)Health Intelligence (gut, cellular health)Gut Intelligence (gut health)Cancer Detect (oral & throat)SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Go to https://viome.com/dave and use code DAVE10 to get 10% off tests and 10% off a 12-month subscriptionWatch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Nature’s Nootropic: https://trukava.com, use code DAVE15 to get 15% offUpgrade Your Air Quality: https://hypoair.com/Dave/Mattress Temperature Tech: https://www.eightsleep.com/dave, use code dave to save $250 on the Pod ProSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

16 Joulu 20221h 4min

How Gut Bacteria Can Change Your Weight & Metabolism – Colleen Cutcliffe, Ph.D. : 1004

How Gut Bacteria Can Change Your Weight & Metabolism – Colleen Cutcliffe, Ph.D. : 1004

Pendulum sponsored this episode.IN THIS EPISODE OF THE HUMAN UPGRADE™…molecular biologist and biochemist Colleen Cutcliffe, Ph.D., returns to the show with brand new science about your gut. She’s a regular guest because she and her team at Pendulum continue to uncover innovative ways to improve your gut health, your metabolism, your immune system, how your brain works and how long you live. This time, Akkermansia’s back in the spotlight, with more than 300 new studies showing connections to weight, metabolism and immunity. A unique and novel probiotic strain (species of bacteria) naturally found in your gastrointestinal tract, Akkermansia muciniphila, directly interacts with your gut lining and helps regulate the mucus lining in your gut. Now, there’s growing evidence showing Akkermansia to be a keystone bacterial strain.This conversation dives into the latest research and what it means for you. You’ll learn how to apply this new knowledge and how to boost Akkermansia in your gut.SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: Go to https://pendulumlife.com and use promo code DAVEVIP to get 20% off your first month of membership. Watch this episode on YouTube!A Pre-Alcohol Probiotic to Offset a Rough Morning After: https://zbiotics.com/dave, use code DAVE to save 15% off your first order. Sleep Better on Natural Memory Foam: https://myessentia.com/daveasprey, use code DAVE to get an extra $100 off an Essentia mattress purchase on top of Essentia’s Holiday 25% off sale. Through Dec. 31, 2022, only. Go Deep on Relaxation & Sleep: https://balooliving.com/dave, use code DAVE for a special discount. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

13 Joulu 202244min

Why Youth Mental Health & Suicide Matters to Everyone – Dr. Mark Goulston : 1003

Why Youth Mental Health & Suicide Matters to Everyone – Dr. Mark Goulston : 1003

IN THIS EPISODE OF THE HUMAN UPGRADE™ … you’ll find out that kids are killing themselves more often and at younger ages. Suicide prevention expert Dr. Mark Goulston joins the show to discuss the very real and very urgent topics of youth mental health and suicide—from pre-teens to teens to young adults. These issues concern everyone, not only families, educators or professionals who connect with young people. Here’s why:Suicide shows up in the top three causes of death in young people between the ages of 10-24, according to 2020 stats from the Centers for Disease Control and Prevention (CDC) WISQARS Leading Causes of Death Reports.Young people are hurting. The National Alliance on Mental Illness reports that nearly 20% of high school students say they’ve had serious thoughts of suicide and 9% have made an attempt to take their lives. Dr. Mark explains that many young people struggling mentally and emotionally feel like they're a burden to everyone. And they don’t have confidence that parents can help them feel better. You’ll learn a lot during this conversation, such as:factors driving teen mental health issues and teen suicide.what’s going on in the teen brain from a developmental perspective that leads them to think that death is a preferable alternative to working through life situations.signs or red flags that a teen is struggling. how parents and adults often can diminish or dismiss teens’ emotions, situations with friends or love relationships.what emotional intelligence skills are most useful for parents/adults to better understand teens.how to talk to teens—whether you’re a parent or a caring adult in a teen’s life.how to improve listening in a culture dominated by tech.how to listen to teens and help them realize and understand their emotions—without cutting them off, interrupting them, or jumping to advice and solutions.when to seek professional intervention.More about Dr. Mark Goulston: He's a retired psychiatrist, former UCLA professor of psychiatry and former FBI and police hostage negotiation trainer. He recently received the “Shine the Light Media Award” from the Los Angeles County Medical Association for bringing attention to teen mental health and suicide. He’s the author or co-author of nine books: “Just Listen: Discover the Secret to Getting Through to Absolutely Anyone,” ranks in the 15 Best Communication Skills Books of All Time.Watch this episode on YouTube!Biostack for High Performance: https://vatellia.com, use code DAVE2022 to save 10% or subscribe and save 15% + receive a free bottle of Kale BusterGet Fit in Five Minutes: https://www.carolbike.com, use code HumanUpgrade to get 2 years of free membership (a total savings of $360) on the CAROL Bike 2.0 and a 100-day home trial.Business Growth With SEO: https://www.stephanspencer.com, get a FREE consultation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

9 Joulu 20221h 1min

How to Do the Work, Meet Your Self and Be Your Most Authentic – Nicole LePera, Ph.D. : 1002

How to Do the Work, Meet Your Self and Be Your Most Authentic – Nicole LePera, Ph.D. : 1002

IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn about a new holistic framework for self-healing and how to heal yourself with prompts, tools and actionable tips.Using the tenants of holistic psychology, Nicole LePera, Ph.D., created a different way to reach people and equip them with the tools necessary to heal themselves. Holistic psychology focuses on the mind, body, and soul in the service of rebalancing the body and nervous system and healing unresolved emotional wounds. It’s all about a daily practice of creating your own wellness by:seeing yourself from a new perspective,breaking negative patterns, healing from your past, andcreating your conscious self.Nicole, the author of the New York Times Bestselling Book “How to Do the Work: Recognize Your Patterns, Heal from Your Past, and Create Your Self,” builds on that theme and goes even deeper with her newly published “How to Meet Your Self: The Workbook for Self-Discovery” workbook.In this conversation, you’ll find out how to:objectively and compassionately observe the physical, mental, and emotional patterns that keep you stuck.deep dive into your ego, trauma and emotions so you can safely do the inner work that can transform your outer world.change ingrained beliefs and habits so you can move toward realizing your authentic self. Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! A Cleaner Nicotine Alternative: https://lucy.co, use code DAVE20 for 20% off your first order of pouches, gums or lozengesMattress Temperature Tech: https://www.eightsleep.com/dave, use code dave to save $250 on the Pod ProTest Your Own Biology: https://knowinglabs.com/dave, use code dave to save 20% off any test kitSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Joulu 202248min

Discovering Blue Zones In America – Dan Buettner : 1001

Discovering Blue Zones In America – Dan Buettner : 1001

IN THIS EPISODE OF THE HUMAN UPGRADE™… Dan Buettner joins the show to talk about the origins and food foundations of Blue Zones. He discusses how they were discovered, what makes them different, and what’s changed for people living there over the past few decades. And the big question—is it still possible to live to 100?Dan, an explorer, National Geographic Fellow, award-winning journalist and producer, and photographer, has studied and written extensively about the five places in the world—dubbed Blue Zones—where people live the longest, healthiest, and often happiest lives. He’s partnered with epidemiologists, anthropologists, medical researchers, demographers, and statisticians to take a data-based approach to everything from genetics to census data.Combining this intensive research with cultural immersion, Dan’s brought out aspects of Blue Zones lifestyles—like food and social connection—that form a foundation for human life quality and longevity. He’s the bestselling author of a series of Blue Zone books.In Dan’s latest Blue Zones adventure, he took a road trip across the United States to explore food and communities. He found that pockets of Blue Zones do exist throughout the U.S. He talked to heritage cooks passing on recipes to younger generations. He uncovered the traditional roots of plant-forward cuisine in the United States and presents both traditional and revolutionary ideas in vegetarian food in his newest book, “The Blue Zones American Kitchen: 100 Recipes to Live to 100.” Stunning photography and recipes show the vitality of both food and people from five distinct areas: Indigenous, Native & Early American, African American, Latin American, Asian American and Regional and Contemporary American.Dan also dug deep into the country’s food history and brings to light the dramatic changes in food processing, regulation, government intervention, and leadership choices that have influenced food supply. He combed through 60 oral histories, scientific reports and academic papers to reconstruct traditional American diets. In “The Blue Zones American Kitchen,” you’ll find out why the 1970s were the worst decade for America’s food environment. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Upgrade Your Air Quality: https://hypoair.com/Dave/Nature’s Nootropic: https://trukava.com, use code DAVE15 to get 15% offMust-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discount. Learn more: Magnesium: The Master Mineral That Conquers Stress – BiOptimizers – #669See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

2 Joulu 202249min

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