Biohacking News Weekly Update : 1383

Biohacking News Weekly Update : 1383

This episode covers:


• FDA Loosening Supplement Warning Labels

The FDA is considering a rule change that would allow supplement companies to include the DSHEA disclaimer only once per package rather than next to every claim. Dave explains why fewer visible warnings could make marketing look more like medical claims, and why biohackers should treat labels as advertising rather than evidence. He shares how to protect yourself now: add one variable at a time, run baseline labs, and rely on data instead of packaging.

Source: https://www.nbcnews.com/health/health-news/fda-supplements-warning-label-rule-change-rfk-jr-rcna249321

• Quantum Sensors for Early Heart Attack Detection

Mayo Clinic is testing a contactless heart-monitoring system called CardiAQ using quantum magnetic sensors and AI noise filtering. The device reads subtle electromagnetic signatures from the heart and compares them to invasive angiography. Dave breaks down why earlier detection of ischemia could shift heart care from reactive treatment to proactive screening — and why building baseline metrics like VO₂max, blood pressure and HRV today will pay off when next-gen diagnostics arrive.

Source: https://www.sandboxaq.com/press/sandboxaq-collaborates-with-mayo-clinic-on-novel-cardiac-diagnostics

• Sauna Detox for Microplastics

Emerging research shows that sweating meaningfully removes plastic-related chemicals like BPA and phthalate metabolites from the body, often more efficiently than blood or urine alone. Sauna use amplifies this effect by increasing circulation, mobilizing stored toxins from tissues, and accelerating sweat-based excretion. When you combine regular heat exposure with reduced environmental plastic contact, you create a powerful detox strategy that targets a chemical burden once thought unavoidable. Dave breaks down how sauna protocols can support toxin elimination, improve cardiovascular resilience, strengthen autonomic balance, and help counteract the metabolic and hormonal disruptions linked to microplastics in modern life.

Source: https://superage.com/can-you-sweat-out-microplastics-in-the-sauna/

• Psychedelics and Longevity Biomarkers

Bryan Johnson treated a guided psilocybin experience as a structured longevity experiment, collecting nearly 250 biomarkers including CGM, stress markers, HRV and Kernel brain imaging. The experiment revealed a surprising metabolic change: mean glucose dropped 8 percent, variability fell 11 percent, and estimated HbA1c moved from 4.7 to 4.4 — similar to months of metformin but after a single session. Dave explores the emerging idea that neuroplastic events might influence glucose regulation through brain-pancreas signaling, while emphasizing the need for supervised, legal use and proper clinical trials.

Source: https://www.businessinsider.com/bryan-johnson-trip-on-mushrooms-five-hours-live-2025-12


• A Mitochondrial Protein that Extends Mouse Lifespan

Researchers boosted the mitochondrial protein COX7RP and extended mouse lifespan by ~6.6 percent while improving insulin sensitivity, lipid handling, endurance and liver fat metabolism. COX7RP supports formation of mitochondrial “supercomplexes,” improving respiratory efficiency and ATP generation. Dave explains how this reinforces lifestyle levers — strength training, aerobic capacity, stabilizing blood sugar — as tools that likely preserve supercomplex architecture and mitochondrial resilience.

Source: https://www.eurekalert.org/news-releases/1109082


All source links provided for direct access to the original research and reporting.


This episode is designed for biohackers, longevity seekers and high-performance listeners who want practical strategies rooted in cutting-edge science. Dave Asprey translates emerging research into actionable upgrades for your biology — from metabolism and mitochondria to nervous system health, detox, and prevention.


New episodes every Tuesday, Thursday, Friday, and Sunday.


Keywords: FDA supplement rule change, supplement warning labels, DSHEA disclaimer removal, supplement regulation risks, quantum cardiac scanner, Mayo Clinic heart attack detection, AI heart monitoring, early ischemia detection technology, sauna detox evidence, sweating out toxins research, BPA phthalate sweat studies, microplastics sauna myth, Bryan Johnson psilocybin experiment, psychedelic longevity research, psychedelic metabolic reset, glucose control psychedelics, HbA1c psilocybin results, continuous glucose monitor insights, mitochondria lifespan research, COX7RP protein aging study, mitochondrial supercomplex benefits, ATP energy output aging, metabolic flexibility longevity, biohacking news update, anti-aging science breakthroughs, evidence-based longevity tools, biological age biomarkers


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• 40 Years of Zen: https://40yearsofzen.com

Timestamps:

0:00 - Intro

0:18 - Story 1: FDA Supplement Label Changes

1:43 - Story 2: CardiAQ Heart Scanner

2:59 - Story 3: Saunas and Microplastics

4:58 - Story 4: Psychedelics and Blood Sugar

8:22 - Story 5: Mitochondrial Longevity Research

10:29 - Weekly Wrap-Up

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Jaksot(1457)

Discover Your Attributes & Get More Out of Yourself – Rich Diviney : 937

Discover Your Attributes & Get More Out of Yourself – Rich Diviney : 937

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Control Blood Glucose: https://pendulumlife.com, sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipmentTasty Keto Bread & Chips: https://www.uprisingfood.com/DAVE, use code DAVE to get $10 off the starter bundleBusiness Growth With SEO: https://www.stephanspencer.com, get a FREE consultationIN THIS EPISODE OF THE HUMAN UPGRADE™...… you’ll learn why developing your attributes may be more important than skills when it comes to getting more out of yourself. Attributes are wired into your internal circuitry, always running in the background, says Rich Diviney. You’re born with attributes. They’re elemental and considered innate traits—not to be confused with personality traits.Rich, a retired Navy SEAL commander, bestselling author, and leadership and human performance expert, explains how attributes determine how you absorb, process, and respond to the world around you. By knowing this, you’ll be able to assess your own attributes and put them into action with SMART steps.In his book, “The Attributes: 25 Hidden Drivers of Optimal Performance,” Rich shows you how mindset, optimism and becoming uniquely resilient to stress can help you become a better human. His approach identifies core attributes needed for success in personal or professional tasks.His ability to choose the right people to be in elite performance groups—like the U.S. Navy SEALs—could be considered a superpower. As the officer in charge of training for a specialized command, Rich was part of the SEAL selection process. He pared down a group of exceptional candidates to a small cadre of the most elite optimal performers. How did he do it? By looking at attributes.It’s Rich's belief that SEALs are not born extraordinary. Instead, they’ve mastered their own mindset to get the most out of their innate abilities to make themselves extraordinary. He believes we all have the power to do this.In “The Attributes,” you’ll find examples of attributes within five distinct categories plus a couple more that don’t fit so neatly: Grit, Mental Acuity, Drive, Leadership and Teamability. So, what are attributes and how are they different than skills? “A lot of times we get seduced by skills, and we don't think about attributes,” Rich says. “And the reason is very simple: skills are not inherent to our nature. They're very visible, which means they're very easy to assess, measure and test and you can put scores around them and stats around them. … Attributes are inherent to our nature. We're all born with levels of adaptability and situational awareness and resilience. Attributes don't dictate our behavior or director behavior; they inform our behavior.” See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

13 Touko 20221h 18min

A Crash Course in How to Build Radical Confidence – Lisa Bilyeu : 936

A Crash Course in How to Build Radical Confidence – Lisa Bilyeu : 936

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Track Blood Glucose: https://www.levelshealth.com/DAVE, sign up for the Beta groupKickstart Autophagy: https://timelinenutrition.com/DAVE, use the code ASPREY10 to get 10% off any planMattress Temperature Tech: https://www.eightsleep.com/dave, use code DAVE to save $250 on the Pod ProIN THIS EPISODE OF THE HUMAN UPGRADE™... …you’ll learn that to be a high performer, you’ve got to have radical confidence to achieve whatever goals you set for yourself. Today’s guest, Lisa Bilyeu, explains how real confidence is an inside job, not something you gain from outside validation. When Lisa co-founded Quest Nutrition, she was a self-professed housewife boxing protein bars in her living room. The company grew 57,000 percent in its first three years and became a billion-dollar brand. Her learning curve was steep and fast and filled with things she didn’t know how to do—yet. She went on to co-found (with her husband, Tom Bilyeu) and serve as president of Impact Theory Studios. It’s a digital-first studio that produces entertaining original content focusing on themes of empowerment. That content has been viewed over half a billion times by a global audience.Lisa oversees in-house development of projects focused on female-driven content for multiple platforms. She hosts the digital series, “Women of Impact.”In her first book, “Radical Confidence: 10 No BS Lessons on Becoming the Hero of Your Own Life,” she shares her journey from a housewife to successful entrepreneur with relatable lessons, anecdotes, and lots of humor.She explains how the “Purgatory of the Mundane” is even more dangerous than hitting rock bottom. She dishes tough love for those of you who are stuck in mind loops that hold you back.From ditching the fairy tale to getting off the couch to putting on goggles when the shit hits the fan, Lisa’s got realistic tips to get you moving. An important part of that momentum is setting boundaries: material, physical, and mental and emotional. She shows you exactly how.She also suggests a fresh perspective on a few things that can help you build “radical” confidence:Manage the voice in your headSet clear boundariesLearn from your mistakesKeep your goals top of mindMaintain self-awareness around your emotions and triggersSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

11 Touko 20221h 11min

Upgrade Spotlight: Find Your Footing in Minimalist Footwear – Xero Shoes : 935

Upgrade Spotlight: Find Your Footing in Minimalist Footwear – Xero Shoes : 935

IN THIS EPISODE OF THE HUMAN UPGRADE™... …you’re listening to a new Upgrade Spotlight series based on what you told me you wanted to hear on this podcast. On one Friday each month, these shorter episodes will feature guests who’ll get right into useful information in a Q&A style. You’ll find out how to improve your energy and upgrade your performance. You’ll also get the latest knowledge about powerful tools and technologies that allow you to change your biology and the environment around you. Introducing Xero Shoes! During this Upgrade Spotlight, you’ll learn how minimalist footwear reduces injury, improves foot strength and supports healthy feet. You’ll learn that getting grounded is a good thing.Today’s guest—serial entrepreneur Steven Sashen—is a competitive sprinter. He knows the mechanics of human feet. He also knows what it feels like to move in shoes that suck. So, he and his wife, Lena Phoenix, founded the footwear company Xero Shoes. They ran headlong into shoe history and shoe science to intentionally create “a MOVEMENT movement” of people with happy, healthy, strong feet in addictively comfortable footwear. “A quarter of the bones and joints of your whole body are in your feet and ankles,” Steven says. “They're supposed to bend and move and flex just like any other joint. If you're wearing shoes that don't let them do that, that function tries unsuccessfully to move into your ankle, your knee, your hip and your back joints. Those joints aren't built for those micro motions that keep you balanced, that give you agility and mobility.”Your feet, and by design the rest of your body, know something’s off with cushioned shoes. So does Steven.“The value of natural movement, the importance of foot health, and all the things that relate to foot health got me going,” he says. “But what really catalyzed it was discovering that what the footwear industry has been doing for 50 years is lying to people– selling people on ideas that they know don't work, but they can't pull back. They can't tell a different story, because they've been promoting this story for so long about arch support, motion control, padding, cushioning, etc.” Research published by the American College of Sports Medicine in 2021, “Stepping Back to Minimal Footwear: Applications Across the Lifespan," showed that minimal footwear leads to improved musculoskeletal health across your lifetime. “It’s all about natural motion,” Steven explains. “Our ancestors didn't have a problem being on their feet all day, every day. It wasn't because they're different from us, it was just that they got used to using their feet correctly. We can still do that any day, anytime, any of age.”CHECK OUT XERO SHOES and the 5,000-MILE SOLE WARRANTY! U.S.: https://xeroshoes.com and EU: https://xeroshoes.euSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

7 Touko 202246min

How to Double Your Energy – Ari Whitten : 934

How to Double Your Energy – Ari Whitten : 934

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Complete Spectrum Hemp + Chinese Herbs: https://radicalrootsherbs.com/DAVE, use code DAVE to get 10% off Meat Sticks, Apple Cider Vinegar and More Good Stuff: https://paleovalley.com/DAVE, use code DAVE to get 15% off your first orderBiostack for High Performance: https://vatellia.com, use code DAVE2022 to save 10% or subscribe and save 15% + receive a free bottle of Kale BusterIN THIS EPISODE OF THE HUMAN UPGRADE™...…you’ll find out why you’re tired, how to fix it and ways to increase your energy. Fatigue is a hidden epidemic, with chronic fatigue syndrome being the most severe end, but most people (in the U.S.) are experiencing some level of being flat-out tired as hell.Guest Ari Whitten, Ph.D. (Cand.), CES, PES, says that as a culture, we have normalized fatigue. In his newest book, “EAT FOR ENERGY: How to Beat Fatigue, Supercharge Your Mitochondria, and Unlock All-Day Energy,” he explains that 5.4 million adults in the U.S. have been diagnosed with chronic fatigue syndrome (the most severe case of fatigue). However, the true fatigue epidemic affects 50 to 100 times more people.This episode’s discussion gets right into the role of mitochondria in human energy. Ari’s research (420 citations in “Eat for Energy”!] is clear. The cause of fatigue is mitochondrial dysfunction, he says. And the biggest factors that affect your mitochondria include:Circadian rhythm dysregulation and poor sleep Carrying too much body fat and too little muscle mass Poor gut and microbiome health Blood sugar dysregulation Nutritional toxicities and deficiencies Neurotransmitter and hormone imbalances So what can you do to increase your energy currency? A lot, as it turns out. When you understand factors like resilience, cell defense, nutrition and supplementation, you’re on your way to better energy. In this conversation, you’ll learn:what’s causing the dysfunction in your mitochondria and how you can repair these critical energy cells. strategies that will double your energy levels. 7 top supplements (and more) that help get your mitochondria back on the energy track. Ari has been studying and teaching natural health science for more than 25 years. He went through his own battle with chronic fatigue that inspired his obsession with energy. For the past seven years, he's focused specifically on improving human energy. His education and work in this area touches on critical aspects of human health from nutrition to physical training, to light science, to psychology, and more. He created The Energy Blueprint science-based lifestyle programs that target brain energy and mitochondria. He also hosts The Energy Blueprint podcast that features world-wide experts on the subject of understanding fatigue and how to get more energy. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Touko 20221h 1min

Relieve Your Back Pain in 4 Steps – Dr. Marcella Madera : 933

Relieve Your Back Pain in 4 Steps – Dr. Marcella Madera : 933

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Sleep Better on Natural Memory Foam: https://myessentia.com, use code DAVEVIP to get an exclusive discountMust-Have Magnesium: https://magbreakthrough.com/DAVE, use code DAVE10 to get a 10% discountControl Blood Glucose: https://pendulumlife.com, sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipmentIN THIS EPISODE OF THE HUMAN UPGRADE™...… you’ll meet a holistic neurosurgeon who’s evolving spine care away from cutting. Dr. Marcella Madera’s integrative approaches to spine problems pair science with holistic healing modalities. This means way better healing for you.Dr. Madera’s innovations in spine treatments include the “Aqua Method,” where photobiomodulated platelet rich plasma meets functional tissue mobilization and movement. You’re going to get exciting new information about this effective form of regenerative medicine and find out if this treatment may be right for you. “It's a very nuanced discussion,” says Dr. Madera. “It's very patient specific. It's very injury specific.”“The term Aqua really gives a description of what we're trying to create in the body and that is more fluidity,” she explains. “And also, water, aqua, is pure. It’s intense at times, depending on the form. And it is soothing at times, depending on the form. And that is how our treatment goes.”Dr. Madera’s four-part system includes: Reveal, Restore, Revitalize, Revel. You could benefit whether you have an old or new injury, or chronic pain.During this episode, she explains how each part is interconnected and helps you heal your spine, or even knee, problems. The Aqua Method’s three-day immersive experience includes a full team of experts focused on your biology, your energy and your state of mind.Dr. Madera, a board-certified neurosurgeon, trained extensively in conventional medicine. Her expertise in spine care includes surgical treatments, approaches, and techniques for degenerative spine disease, spine tumors, and degenerative deformity. She started a private practice in in Austin, Texas where she combines her technical spine care with stem cell treatments and holistic modalities like herbs, energy modalities, Chinese healing practices, autogenic training and diet modification.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Get a $1,000 discount on the Aqua Method at Austin Integrative Spine in Austin, Texas. Call the clinic at 512-817-4600 and mention discount code DAVEASPREY.More about Dr. Marcella Madera: She’s experienced in open surgery, minimally invasive surgery, endoscopic spine surgery, and regenerative/stem cell procedures. She’s been an assistant professor of Surgery at the University of Texas at Austin Dell Medical School. She also travelled throughout Europe and the U.S. to learn progressive endoscopic techniques and regenerative medicine practices. She completed a Spine Fellowship and faculty instructorship at Johns Hopkins School of Medicine.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Touko 20221h 6min

Mini-Episode: Cool Facts Friday #22

Mini-Episode: Cool Facts Friday #22

Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.GlyNAC (glycine and N-acetylcysteine) can correct glutathione deficiency, oxidative stress, mitochondrial dysfunction and mitophagy abnormalities to help you live longer.Moms and dads think — and react — differently to newborn baby smells.Clock and Cycle factors control circadian rhythm and protect your eyes as you age. Oleic acid produced in the brain helps regulate memory, learning, and mood; promotes neurogenesis; and increases cell proliferation.EPISODE SPONSOR: The Eng3 NanoVi device helps repair oxidative stress damage and support the body’s natural repair mechanisms. https://eng3corp.com/DAVE/. Learn more: The Anti-Aging Science Behind the NanoVi Device – Rowena Gates & Hans Eng – #416.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

29 Huhti 202215min

Great Relationships Start with You & Hard Truths – Gary John Bishop : 932

Great Relationships Start with You & Hard Truths – Gary John Bishop : 932

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Nature’s Nootropic: https://trukava.com, use code DAVE15 to get 15% offNAD+ for Brain Health: https://innovativemedicine.com/DAVE and save 20%Support Immune & Digestive Health: https://justthrivehealth.com, use code ASPREY to get 15% offIN THIS EPISODE OF THE HUMAN UPGRADE™...…you’ll learn that one of the major life upgrades you can make includes your relationships. Personal development expert Gary John Bishop doesn’t buy into mainstream notions of what makes a happy relationship. Not 50/50 effort, not compromise, not molding yourself into what your partner wants. It’s just you and some hard truths.What this episode is not about;Blame or providing communication tipsHow to change or cope with your partner and personality types Healing past trauma or understanding fear of commitment Instead, you’ll get the ingredients to creating a real, lasting and profound connection with another human being.“There's some, again, cold truths that you have to face and then really have to start to take on,” he says, “but in a way that it's not always going to go your way. You're not always going to get this thing flowing the way you would want it to go, but your job is to keep bringing yourself to this phenomenon in a way that's consistent with you, who you are, what you're about. And powerfully managing all that you might do to undermine it.”Gary, the New York Times bestselling author of the Unfu*k book series, uses an “urban philosophy” approach that’s both simple and enlightening. In his latest book, “LOVE UNFU*kED Getting Your Relationship Sh!t Together,” he puts the focus on relationships. “The quality of your relationships dictates the quality of your life,” he says in “LOVE UNFU*kED.” This conversation gets right to the heart of what you can do to make changes that stick in all areas of your life.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

28 Huhti 20221h 6min

WetSpace, Crypto & Taking on Big Tech – Allie Rae : 931

WetSpace, Crypto & Taking on Big Tech – Allie Rae : 931

WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Gifts for Mother’s Day – or Any Day: Give the sensation of a hug, deep relaxation and better sleep: https://balooliving.com/dave, use code DAVE for a special discountHealth Upgrades with Custom Lab Testing and Your Own Data: https://get-base.com/DAVE, use code DAVE to get 20% off your first month of membershipMeat Sticks, Apple Cider Vinegar and More Good Stuff: https://paleovalley.com/DAVE, use code DAVE to get 15% off your first orderIN THIS EPISODE OF THE HUMAN UPGRADE™...You’ll be part of a candid conversation about choice and freedom. And, why it’s important to be able to make a living in your chosen line of work without restriction or judgment. That’s just part of being a better-performing human.Guest Allie Rae, a wife, mother, retired nurse and Navy veteran, shares her unusual entrepreneurial journey within the adult sex entertainment industry. It may be a different topic than you expect on this show, but it’s a look at innovation opening up alternative ways of doing business outside restrictive Big Tech.She’s CEO of a brand-new online adult platform called WetSpace. You may have heard about or know of the OnlyFans platform. WetSpace is similar, but not direct competition. Allie Rae saw a problem with payment systems and banking restrictions and set out to find a solution.“At this point, this is no longer a hobby, it's a business for me,” Allie Says. “And as any business in any industry, you want to protect your business and provide stability and have long-term prosperity.”We get into some cool topics:Why Allie Rae created WetSpace;How cryptocurrency fits into her plans;The influence of Big Tech; andHow advocacy—not regulation—can guide the growth of the adult sex industry.Today’s show looks at personal choice and freedom—both yours and other people’s. It challenges stigma, advocates for better systems of work, and supports creativity and business acumen.it's important that we think about both sex, because that's one of those big things that nourishes us, and also think about what's going on in the world around us, that environment that controls your biology.It matters that you’re able to choose what to do to and with your body, your energy, and your time. You get to choose to live your values—and so does everyone else. Even if you don’t agree. Being kind and respectful goes a long way in creating communities that allow you to be the highest performing human you want to be.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

26 Huhti 20221h 9min

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