Special Encore: Who’s Disrupting — and Funding — the AI Boom

Special Encore: Who’s Disrupting — and Funding — the AI Boom

Original Release Date: November 13, 2025

Live from Morgan Stanley’s European Tech, Media and Telecom Conference in Barcelona, our roundtable of analysts discusses tech disruptions and datacenter growth, and how Europe factors in.

Read more insights from Morgan Stanley.


----- Transcript -----


Paul Walsh: Welcome to Thoughts on the Market. I'm Paul Walsh, Morgan Stanley's European Head of Research Product.

Today we return to my conversation with Adam Wood. Head of European Technology and Payments, Emmet Kelly, Head of European Telco and Data Centers, and Lee Simpson, Head of European Technology.

We were live on stage at Morgan Stanley's 25th TMT Europe conference. We had so much to discuss around the themes of AI enablers, semiconductors, and telcos. So, we are back with a concluding episode on tech disruption and data center investments.

It's Thursday the 13th of November at 8am in Barcelona.

After speaking with the panel about the U.S. being overweight AI enablers, and the pockets of opportunity in Europe, I wanted to ask them about AI disruption, which has been a key theme here in Europe. I started by asking Adam how he was thinking about this theme.

Adam Wood: It’s fascinating to see this year how we've gone in most of those sectors to how positive can GenAI be for these companies? How well are they going to monetize the opportunities? How much are they going to take advantage internally to take their own margins up? To flipping in the second half of the year, mainly to, how disruptive are they going to be? And how on earth are they going to fend off these challenges?

Paul Walsh: And I think that speaks to the extent to which, as a theme, this has really, you know, built momentum.

Adam Wood: Absolutely. And I mean, look, I think the first point, you know, that you made is absolutely correct – that it's very difficult to disprove this. It's going to take time for that to happen. It's impossible to do in the short term. I think the other issue is that what we've seen is – if we look at the revenues of some of the companies, you know, and huge investments going in there.

And investors can clearly see the benefit of GenAI. And so investors are right to ask the question, well, where's the revenue for these businesses?

You know, where are we seeing it in info services or in IT services, or in enterprise software. And the reality is today, you know, we're not seeing it. And it's hard for analysts to point to evidence that – well, no, here's the revenue base, here's the benefit that's coming through. And so, investors naturally flip to, well, if there's no benefit, then surely, we should focus on the risk.

So, I think we totally understand, you know, why people are focused on the negative side of things today. I think there are differences between the sub-sectors. I mean, I think if we look, you know, at IT services, first of all, from an investor point of view, I think that's been pretty well placed in the losers’ buckets and people are most concerned about that sub-sector…

Paul Walsh: Something you and the global team have written a lot about.

Adam Wood: Yeah, we've written about, you know, the risk of disruption in that space, the need for those companies to invest, and then the challenges they face. But I mean, if we just keep it very, very simplistic. If Gen AI is a technology that, you know, displaces labor to any extent – companies that have played labor arbitrage and provide labor for the last 20 - 25 years, you know, they're going to have to make changes to their business model.

So, I think that's understandable. And they're going to have to demonstrate how they can change and invest and produce a business model that addresses those concerns. I'd probably put info services in the middle. But the challenge in that space is you have real identifiable companies that have emerged, that have a revenue base and that are challenging a subset of the products of those businesses. So again, it's perfectly understandable that investors would worry. In that context, it's not a potential threat on the horizon. It's a real threat that exists today against certainly their businesses.

I think software is probably the most interesting. I'd put it in the kind of final bucket where I actually believe… Well, I think first of all, we certainly wouldn't take the view that there's no risk of disruption and things aren't going to change. Clearly that is going to be the case.

I think what we'd want to do though is we'd want to continue to use frameworks that we've used historically to think about how software companies differentiate themselves, what the barriers to entry are. We don't think we need to throw all of those things away just because we have GenAI, this new set of capabilities. And I think investors will come back most easily to that space.

Paul Walsh: Emmet, you talked a little bit there before about the fact that you haven't seen a huge amount of progress or additional insight from the telco space around AI; how AI is diffusing across the space. Do you get any discussions around disruption as it relates to telco space?

Emmet Kelly: Very, very little. I think the biggest threat that telcos do see is – it is from the hyperscalers. So, if I look at and separate the B2C market out from the B2B, the telcos are still extremely dominant in the B2C space, clearly. But on the B2B space, the hyperscalers have come in on the cloud side, and if you look at their market share, they're very, very dominant in cloud – certainly from a wholesale perspective.

So, if you look at the cloud market shares of the big three hyperscalers in Europe, this number is courtesy of my colleague George Webb. He said it's roughly 85 percent; that's how much they have of the cloud space today. The telcos, what they're doing is they're actually reselling the hyperscale service under the telco brand name.

But we don't see much really in terms of the pure kind of AI disruption, but there are concerns definitely within the telco space that the hyperscalers might try and move from the B2B space into the B2C space at some stage. And whether it's through virtual networks, cloudified networks, to try and get into the B2C space that way.

Paul Walsh: Understood. And Lee maybe less about disruption, but certainly adoption, some insights from your side around adoption across the tech hardware space?

Lee Simpson: Sure. I think, you know, it's always seen that are enabling the AI move, but, but there is adoption inside semis companies as well, and I think I'd point to design flow. So, if you look at the design guys, they're embracing the agentic system thing really quickly and they're putting forward this capability of an agent engineer, so like a digital engineer. And it – I guess we've got to get this right. It is going to enable a faster time to market for the design flow on a chip.

So, if you have that design flow time, that time to market. So, you're creating double the value there for the client. Do you share that 50-50 with them? So, the challenge is going to be exactly as Adam was saying, how do you monetize this stuff? So, this is kind of the struggle that we're seeing in adoption.

Paul Walsh: And Emmet, let's move to you on data centers. I mean, there are just some incredible numbers that we've seen emerging, as it relates to the hyperscaler investment that we're seeing in building out the infrastructure. I know data centers is something that you have focused tremendously on in your research, bringing our global perspectives together. Obviously, Europe sits within that. And there is a market here in Europe that might be more challenged. But I'm interested to understand how you're thinking about framing the whole data center story? Implications for Europe. Do European companies feed off some of that U.S. hyperscaler CapEx? How should we be thinking about that through the European lens?

Emmet Kelly: Yeah, absolutely. So, big question, Paul. What…

Paul Walsh: We've got a few minutes!

Emmet Kelly: We've got a few minutes. What I would say is there was a great paper that came out from Harvard just two weeks ago, and they were looking at the scale of data center investments in the United States. And clearly the U.S. economy is ticking along very, very nicely at the moment. But this Harvard paper concluded that if you take out data center investments, U.S. economic growth today is actually zero.

Paul Walsh: Wow.

Emmet Kelly: That is how big the data center investments are. And what we've said in our research very clearly is if you want to build a megawatt of data center capacity that's going to cost you roughly $35 million today.

Let's put that number out there. 35 million. Roughly, I'd say 25… Well, 20 to 25 million of that goes into the chips. But what's really interesting is the other remaining $10 million per megawatt, and I like to call that the picks and shovels of data centers; and I'm very convinced there is no bubble in that area whatsoever.

So, what's in that area? Firstly, the first building block of a data center is finding a powered land bank. And this is a big thing that private equity is doing at the moment. So, find some real estate that's close to a mass population that's got a good fiber connection. Probably needs a little bit of water, but most importantly needs some power.

And the demand for that is still infinite at the moment. Then beyond that, you've got the construction angle and there's a very big shortage of labor today to build the shells of these data centers. Then the third layer is the likes of capital goods, and there are serious supply bottlenecks there as well.

And I could go on and on, but roughly that first $10 million, there's no bubble there. I'm very, very sure of that.

Paul Walsh: And we conducted some extensive survey work recently as part of your analysis into the global data center market. You've sort of touched on a few of the gating factors that the industry has to contend with. That survey work was done on the operators and the supply chain, as it relates to data center build out.

What were the key conclusions from that?

Emmet Kelly: Well, the key conclusion was there is a shortage of power for these data centers, and…

Paul Walsh: Which I think… Which is a sort of known-known, to some extent.

Emmet Kelly: it is a known-known, but it's not just about the availability of power, it's the availability of green power. And it's also the price of power is a very big factor as well because energy is roughly 40 to 45 percent of the operating cost of running a data center. So, it's very, very important. And of course, that's another area where Europe doesn't screen very well.

I was looking at statistics just last week on the countries that have got the highest power prices in the world. And unsurprisingly, it came out as UK, Ireland, Germany, and that's three of our big five data center markets. But when I looked at our data center stats at the beginning of the year, to put a bit of context into where we are…

Paul Walsh: In Europe…

Emmet Kelly: In Europe versus the rest. So, at the end of [20]24, the U.S. data center market had 35 gigawatts of data center capacity. But that grew last year at a clip of 30 percent. China had a data center bank of roughly 22 gigawatts, but that had grown at a rate of just 10 percent. And that was because of the chip issue. And then Europe has capacity, or had capacity at the end of last year, roughly 7 to 8 gigawatts, and that had grown at a rate of 10 percent.

Now, the reason for that is because the three big data center markets in Europe are called FLAP-D. So, it's Frankfurt, London, Amsterdam, Paris, and Dublin. We had to put an acronym on it. So, Flap-D. Good news. I'm sitting with the tech guys. They've got even more acronyms than I do, in their sector, so well done them.

Lee Simpson: Nothing beats FLAP-D.

Paul Walsh: Yes.

Emmet Kelly: It’s quite an achievement. But what is interesting is three of the big five markets in Europe are constrained. So, Frankfurt, post the Ukraine conflict. Ireland, because in Ireland, an incredible statistic is data centers are using 25 percent of the Irish power grid. Compared to a global average of 3 percent.

Now I'm from Dublin, and data centers are running into conflict with industry, with housing estates. Data centers are using 45 percent of the Dublin grid, 45. So, there's a moratorium in building data centers there. And then Amsterdam has the classic semi moratorium space because it's a small country with a very high population.

So, three of our five markets are constrained in Europe. What is interesting is it started with the former Prime Minister Rishi Sunak. The UK has made great strides at attracting data center money and AI capital into the UK and the current Prime Minister continues to do that. So, the UK has definitely gone; moved from the middle lane into the fast lane. And then Macron in France. He hosted an AI summit back in February and he attracted over a 100 billion euros of AI and data center commitments.

Paul Walsh: And I think if we added up, as per the research that we published a few months ago, Europe's announced over 350 billion euros, in proposed investments around AI.

Emmet Kelly: Yeah, absolutely. It's a good stat. Now where people can get a little bit cynical is they can say a couple of things. Firstly, it's now over a year since the Mario Draghi report came out. And what's changed since? Absolutely nothing, unfortunately. And secondly, when I look at powering AI, I like to compare Europe to what's happening in the United States. I mean, the U.S. is giving access to nuclear power to AI. It started with the three Mile Island…

Paul Walsh: Yeah. The nuclear renaissance is…

Emmet Kelly: Nuclear Renaissance is absolutely huge. Now, what's underappreciated is actually Europe has got a massive nuclear power bank. It's right up there. But unfortunately, we're decommissioning some of our nuclear power around Europe, so we're going the wrong way from that perspective. Whereas President Trump is opening up the nuclear power to AI tech companies and data centers.

Then over in the States we also have gas and turbines. That's a very, very big growth area and we're not quite on top of that here in Europe. So, looking at this year, I have a feeling that the Americans will probably increase their data center capacity somewhere between – it's incredible – somewhere between 35 and 50 percent. And I think in Europe we're probably looking at something like 10 percent again.

Paul Walsh: Okay. Understood.

Emmet Kelly: So, we're growing in Europe, but we're way, way behind as a starting point. And it feels like the others are pulling away. The other big change I'd highlight is the Chinese are really going to accelerate their data center growth this year as well. They've got their act together and you'll see them heading probably towards 30 gigs of capacity by the end of next year.

Paul Walsh: Alright, we're out of time. The TMT Edge is alive and kicking in Europe. I want to thank Emmett, Lee and Adam for their time and I just want to wish everybody a great day today. Thank you.

(Applause)

That was my conversation with Adam, Emmett and Lee. Many thanks again to them. Many thanks again to them for telling us about the latest in their areas of research and to the live audience for hearing us out. And a thanks to you as well for listening.

Let us know what you think about this and other episodes by living us a review wherever you get your podcasts. And if you enjoy listening to Thoughts on the Market, please tell a friend or colleague about the podcast today.

Jaksot(1538)

Why Shutdown Standoff Raises Stakes for Healthcare

Why Shutdown Standoff Raises Stakes for Healthcare

Our analysts Ariana Salvatore and Erin Wright explain the pivotal role of healthcare in negotiations to end the government shutdown.Read more insights from Morgan Stanley.----- Transcript -----Ariana Salvatore: Welcome to Thoughts on the Market. I'm Ariana Salvatore, Morgan Stanley's U.S. Public Policy Strategist. Erin Wright: And I'm Erin Wright, U.S. Healthcare Services Analyst. Ariana Salvatore: Today we'll talk about what the U.S. government shutdown means for healthcare. It's Thursday, October 30th at 12pm in New York. Thus far, it seems like markets haven't really been paying too much attention to the government shutdown. Obviously, we're aware of the cumulative economic impact that builds every week that it lasts. But we haven't seen any movement from the political front either this week or last, which signals that it could be going on for a while longer. That being said, the end of this month is an important catalyst for a few reasons. First of all, you have the potential rollover of SNAP benefits. You have another potential missed military paycheck. And most importantly, the open enrollment period for healthcare plans. Polling is still showing neither side coming out on top with a clear advantage. Absent that changing, you probably need to see one of two things happen to have any movement forward on this front. Either more direct involvement from President Trump as he wraps up the APEC meeting or some sort of exogenous economic event, like a strike from air traffic controllers. Those types of events obviously are difficult to predict this far in advance. But up until now we know that President Trump has not really been involved in the debate. And the FAA seems to be operating a little bit with delays, but as usual. So, Erin, let's pivot to what's topical in here from a healthcare policy perspective. What are investors that you speak with paying the most attention to? Erin Wright: You bring up some important points Ariana. But from a policy perspective, it's very much an always top of mind for healthcare investors here. Right now, it is a key negotiating factor when it comes to the government shutdown. So, the shutdown debate is predominantly centered around the Affordable Care Act or the healthcare exchanges. This was a part of Obamacare. It was a program where individuals can purchase standalone health insurance through an exchange marketplace.The program has been wildly popular. It's been wildly popular in recent years with 24 million members. Growing 30 per cent last year, particularly with enhanced subsidies that are being offered today. So those subsidies are expected to expire at the end of this year, and those exchange members could be left with some real sticker shock – especially when we're going to see premium increases that could, on average, increase about 25 to 30 percent, in some states even more. So, folks are really starting to see that now. November 1st will be a key date here as open enrollment period begins. Ariana Salvatore: Right. So, as you mentioned, this is pretty key to the entire shutdown debate. Republicans are in favor of letting the expanded subsidies roll off. Democrats want to restore them to that COVID level enhancement. Of course, there's probably some middle path here, and we have seen some background reporting indicating that lawmakers are talking about a potential middle path or concession. So, talk me through what's on the table in terms of negotiating a potential compromise or extension of these subsidies. Erin Wright: So, we could see a permutation of outcomes here. Maybe we don't get a full extension, but we could see something partial come through. We could see something in terms of income caps, which restrict, kind of, the level of participants in the AC exchanges. You could see out-of-pocket minimums, which would eliminate some of those shadow members that we've been seeing and have been problematic across the space. And then you could also grandfather in some existing members that get subsidies today. So, all of those could offer some degrees of positive. And some degrees of relief when it comes to broader healthcare services, when it comes to insurance companies, when it comes to others that are participating in this program, as well as the individuals themselves. So, it's really a patient dynamic that's getting real here. A lot is on the table, but a lot is at stake with the potential for the sunsetting of these subsidies to drive 4 million in uninsured lives. So, it is meaningful, and I think that that's something we have to kind of put into perspective here.So, would love to know Ariana though, beyond healthcare, what are some of those key debates in terms of the negotiations around the shutdown? Ariana Salvatore: Healthcare really is central to this debate. So aside from just the ACA subsidies that we talked about, some Democrats have also been pushing for a repeal or rollback of some of the pieces of the One Big Beautiful Bill Act that passed earlier this year. That was the fiscal bill of Republicans passed through the reconciliation process – that included some cuts to Medicaid down the line. So, there's been talk around that front. I think more of a clear path on the subsidies front, because that seems to be something that Republicans are treating as an absolute no-go. Some of the other really key debates are around just kind of how to keep the ball rolling while we're still in the shutdown. So, I mentioned SNAP at first, the potential release of some contingency funds there. Again, the military paychecks are really critical. And, of course, what this all means for incoming data, which is really important – not just for investors but also for the Fed, as it kind of calibrate[s] their next move. In particular, as we head into the December meeting. I think we got a little bit of a hawkish surprise in yesterday's meeting, and that's something that investors were not expecting. So, obviously the longer that this goes on, the more those risks just continue to grow, and this deadline that we're talking about is a really critical one. It's coming up soon. So we should have a sense of how our prognosis pans out in the coming days. Thanks for the conversation, Erin. Erin Wright: Great talking to you, Ariana. Ariana Salvatore: And to our audience, thanks for listening. Let us know what you think by leaving us a review wherever you listen. And if you like Thoughts on the Market, tell a friend or colleague about the podcast today.

30 Loka 20255min

M&A Poised to Gain Momentum

M&A Poised to Gain Momentum

Our Head of Corporate Credit Research Andrew Sheets explains why the recent revival of M&A activity has room to accelerate.Read more insights from Morgan Stanley.----- Transcript -----Andrew Sheets: Welcome to Thoughts on the Market. I'm Andrew Sheets, Head of Corporate Credit Research at Morgan Stanley. Today – a discussion of merger and acquisition activity or M&A. Last year, we had a view that this activity would pick up significantly. We think we're seeing that increase now. It has further to go. It's Wednesday, October 29th at 2pm in London. We have been firm believers at Morgan Stanley in a significant multi-year uplift in global merger and acquisition activity or M&A. That conviction remains. The incentives for this type of action are strong in our view; activity still lags what fundamentals would suggest, and supportive regulatory shifts are real. M&A has now returned, and importantly, we think there's much further to go. Indeed, M&A is very closely linked to corporate confidence, and we think investors need to consider the possibility that we'll see an even bigger surge in this confidence – or a boom. First, policy uncertainty is declining as U.S. tax legislation has now passed, and tariff rates get finalized. It's the relative direction of this uncertainty that we think matters most for corporate confidence. Second, interest rates are declining with the Fed, European Central Bank, and Bank of England all set to cut rates further over the next 12 months. Third, bank capital requirements may decline in the view of Morgan Stanley analysts, which would unlock more lending for these types of transactions. Fourth, and very importantly, the regulatory backdrop is becoming more accommodative in both the U.S. and in Europe. Indeed, we think that companies may think that this is going to be the most permissive regulatory window for transactions that they might get for some time. Fifth, private equity, which is a big driver of M&A activity, is sitting on over $4 trillion of dry powder in our view – at a time when credit markets look very wide open for financing their transactions. And finally, we're seeing a surge in capital expenditure on Morgan Stanley estimates, which we see as a sign of rising corporate confidence, and importantly an urgency to act – with corporates far less content to simply sit back and repurchase their stock. All of these favorable conditions together argue for activity to push even higher. We forecast global M&A volumes to increase by 32 percent this year, an additional 20 percent next year, and reach $7.8 trillion in volume in 2027. This is a global story with M&A rising across regions, especially in Japan. It has cross-asset implications with M&A already being one of the biggest drivers of bond outperformance within the U.S. high-yield market. And this is also a story where we see a lot of value in bringing together macro and micro perspectives. While we think the top-down conditions look favorable for all the reasons I just mentioned, we also see a very encouraging picture bottom up. We polled a large number of Morgan Stanley sector analyst teams and asked them about M&A conditions in their sector. A large majority of them see more activity. So, where could these more specific implications lie? Well, as you heard on yesterday's episode, Healthcare and Biotech may see an uptick in activity. In the U.S., we also think that Banking and Media stand out. In Europe, Business Services, Metals and Mining, and Telecom seem most ripe for more M&A. Aerospace and Defense is an interesting sector that may see more M&A within multiple regions, including the U.S. and Europe, as companies look for scale. And with smaller companies trading at a valuation discount to their larger peers across the world, Morgan Stanley analysts generally see the strongest case for activity in larger companies acquiring these smaller ones. Thank you as always for your time. If you find Thoughts on the Market useful, let us know by leaving a review wherever you listen, and also tell a friend or colleague about us today.

29 Loka 20254min

A Turnaround in Sight for Healthcare?

A Turnaround in Sight for Healthcare?

Our U.S. Biotech and Biopharma analysts Sean Laaman and Terence Flynn discuss the latest developments that could be positioning the healthcare sector for strong outperformance.Read more insights from Morgan Stanley.----- Transcript -----Sean Laaman: Welcome to Thoughts on the Market. I'm Sean Laaman, Morgan Stanley's U.S. Small and Mid-Cap Biotech Analyst. Terence Flynn: And I'm Terence Flynn, Morgan Stanley's U.S. Biopharma Analyst. Sean Laaman: Today, we'll discuss how a rally in the healthcare sector is being driven by more favorable macro conditions. It's Tuesday, October 28th at 10am in New York. So, Terence, healthcare has lagged the broader market year-to-date, and valuations have been near historical lows. But recent weeks show strengthening performance. Policy headwinds have been front and center.What's changed in the regulatory environment and how is the biopharma sector adapting to these pricing and tariff dynamics? Terence Flynn: Sean, as you know, with many other sectors, tariffs were initially a focus earlier this year. But a number of companies in our space have subsequently announced significant U.S. manufacturing investments to reshore supply chains. And hence, the market's less focused on tariffs in our space right now. But the other policy dynamic and focus is what's called Most Favored Nation or MFN drug pricing. Now, this is where the President's been focused on aligning U.S. drug prices with those in other developed countries. And recently we've seen several companies announce agreements with the administration along these lines, which importantly has provided investors with more visibility here. And we're watching to see if additional agreements get announced. Sean Laaman: Got it. Another hurdle for Large-cap biopharma is a looming expiration of patents with [$]177 billion exposed by 2030. How is this shaping M&A trends and strategic priorities? Terence Flynn: For sure. I mean, as you know, Sean, patent expiry is our normal part of the life cycle of drug development. Every company goes through this at some point, but this does put the focus on company's internal pipelines to continue to progress while also being able to access external innovation via M&A. Recently we have started to see a pickup in deal activity, which could bode well for performance in SMID-cap biotech. Sean Laaman: At the same time, you believe relative valuations look compelling for Large-cap biopharma. Where are valuations versus where they've been historically? What's driving this and how should investors think about positioning? Terence Flynn: Absolutely. Look, on a price to earnings multiple, the sector's trading at about a 30 percent discount to the S&P 500 right now. Now that's in line with prior periods of policy uncertainty. But as policy visibility improves, we expect the focus will shift back to fundamentals. Now, positioning to me still feels light here, given some of the patent cliff dynamics we just discussed. Now, Sean, with the Fed moving toward rate cuts, how do you see this impacting your sector on the biotech side? Sean Laaman: Well, Terence, particularly in my space, which is Small- and Mid-cap biotech companies, they're typically capital consumers are not capital producers. They're particularly sensitive to the current rate environment.Therefore, they're sensitive to spending on pipeline. They're sensitive to M&A. So, as rates come down, we expect more spending on pipeline and more M&A activity, which is generally positive for the sector. Looking forward, biotech sector is generally the best performing sector on a six-to-12-month timeframe post the first rate cut. Terence Flynn: Great. You've also talked about this SMID to Big thesis on the biotech side. Can you explain what's driving that? Sean Laaman: Sure Terence. There’s three pieces to the SMID to Big thematic. So, we in SMID-cap biotech, we cover 80 to 90 companies. About a third of those are newly, kind of profitable companies. Those companies are turning from being capital consumers to capital producers. We see about $15 billion of cash on balance sheets for 2025, going to north of 130 billion by 2030. That's the first piece. The second piece is due to regulatory uncertainty at the USFDA. We're seeing more attractive valuations amongst clinical stage names. That's the second piece. And third piece relates to your coverage, Terence. I refer back to that [$]177 billion of LOE. So, we expect generally that M&A activity will be quite high amongst our sector. Terence Flynn: And let's not forget about AI, which has implications across the healthcare space. How much is this changing the dynamic in biotech, Sean? Sean Laaman: It is changing, but we're really at the beginning. I think there's three things to think about. The first one is faster trial recruitment. The second one is faster regulatory submissions. And the third one, which is the most interesting, but we're really at the beginning of, is faster time to appropriately targeted molecules. Terence Flynn: Great. And maybe lastly, what are the key risks and catalysts for SMID-cap biotech in the current environment? Sean Laaman: As always, we're focused on pipeline failures in terms of risk. Secondly, in terms of risk, we're looking at regulatory risk at the FDA. And thirdly, we're looking at the rise in China biotech and the competitive dynamic there.Whether you're watching large cap biopharma, M&A moves, or the rise of cash-rich, SMID-cap biotechs, the healthcare sector setup is unlike anything we've seen in years.Terence, thanks for speaking with me. Terence Flynn: Always a pleasure to be on the show. Thanks for having me, Sean. Sean Laaman: And thanks for listening. If you enjoy Thoughts on the Market, please leave us a review wherever you listen and share the podcast with a friend or colleague today.

28 Loka 20255min

Will the Stock Market Rally Continue?

Will the Stock Market Rally Continue?

Our CIO and Chief U.S. Equity Strategist Mike Wilson discusses the outlook for stocks after the preliminary U.S.-China trade agreement and ahead of the Fed meeting and big tech earnings.Read more insights from Morgan Stanley.----- Transcript -----Welcome to Thoughts on the Market. I'm Mike Wilson, Morgan Stanley’s CIO and Chief U.S. Equity Strategist. Today on the podcast I’ll be discussing the remaining hurdles for equities after what appears to be a preliminary trade deal with China.It's Monday, October 27th at 11:30am in New York. So, let’s get after it.Over the past few weeks, trade tensions between the U.S. and China escalated once again focused on rare earths and technology transfers with each country playing its strongest card. Over the weekend, it appears that we have at least a preliminary agreement to de-escalate these tensions which means avoiding prohibitively high tariffs that were scheduled to go on at the end of this month. While we don’t have many details on what has been agreed to, it appears that critical rare earths will continue to ship to the U.S. while technology transfer restrictions by the U.S. to China will ease. Presumably, Fentanyl tariffs of 20 percent on China are likely to be part of any broader agreement between Presidents Trump and Xi, if they end up meeting at the upcoming Asia Pacific Economic Cooperation forum.Given the sharp sell-off in stocks a few weeks ago on the news of trade tensions re-escalating, it’s not surprising that stocks are rallying sharply this morning on news of a possible deal from last week’s talks. Our attention now turns to the other big events this week. First, the Federal Reserve is meeting tomorrow and Wednesday to decide its next move on monetary policy. There is a broad consensus view that the Fed will cut another 25 basis points but there are very different views about how they will address its balance sheet run-off known as quantitative tightening, or QT. Based on my conversations, there is a growing consensus view for the Fed to announce the end of QT but uncertainty around the timing. Our house view is for the Fed to wait until the January meeting to make this official with an end of the program in February. Others believe the Fed could announce something as early as this week. That dispersion in expectations does create some room for disappointment from markets, especially given the recent increase in funding market spreads. More specifically, the widening in spreads suggests banking reserves may already be too low and restrictive for the pick-up in economic activity and capital spending that requires more liquidity. Second, earnings revision breadth has rolled over sharply the past few weeks. Most of this decline is due to normal seasonality and the fact that revisions breadth had reached unsustainably high levels since bottoming out in April. Therefore, a reset should be expected as we previewed over a month ago. Nevertheless, it needs to stabilize and push higher again for stocks to continue their advance in my view. Perhaps most importantly for the S&P 500 is the fact that all of the hyperscalers are reporting this week and will likely determine if revision breadth rebounds. It will also be important to see how those stocks react to what is likely to be continued aggressive guidance on AI capex plans. Since April, the hyperscaler stocks have rewarded higher guidance on spending. Should that change, we may see a different tone to how these companies discuss their spending plans. Bottom line, I remain bullish on my 12 month view for U.S. stocks based on what I believe will be better and broader growth in earnings next year. Nevertheless, the near term window remains a bit cloudy on trade, Fed policy shifts and earnings revisions breadth. Stay patient with new capital deployment and look to take advantage of downdrafts when they arise like a few weeks ago. Thanks for tuning in; I hope you found it informative and useful. Let us know what you think by leaving us a review. And if you find Thoughts on the Market worthwhile, tell a friend or colleague to try it out!

27 Loka 20253min

What Happens to Software Developers as AI Can Code?

What Happens to Software Developers as AI Can Code?

Our U.S. Software Analyst Sanjit Singh explains how AI is reshaping software development and why the future for the sector may be brighter – and busier – than ever.Read more insights from Morgan Stanley.----- Transcript -----Welcome to Thoughts on the Market. I’m Sanjit Singh, the U.S. Software Analyst at Morgan Stanley.Today: how AI is transforming software and what that means for developers.It’s Friday, October 24th, at 10am in New York.There's been a lot of news stories and anecdotal accounts about AI taking over jobs, especially in the software industry. You may have heard of vibe coding, where people can use natural language prompts, guiding AI to build software applications. So yes, AI is creating a world where software writes itself. But at the same time, the demand for human creativity only grows.The introduction of AI coding assistants has dramatically expanded what software can do, fueling a surge in both the volume of code and the complexity of projects. But instead of shrinking the developer workforce, AI is actually supporting continued growth in developer headcount, even as productivity soars.We’re estimating the software development market will grow at a 20 percent compound annual growth rate, reaching $61 billion by 2029. And that’s up from $24 billion in 2024. And in terms of the developer population, [research] firms like IDC expect it to jump from 30 million paid developers in 2024 to 50 million by 2029 – that’s a 10 percent annual growth rate. Even the most conservative estimates, like those from the U.S. Bureau of Labor Statistics, see developer jobs growing roughly 2 percent per year through 2033, outpacing overall employment growth.So, what does this mean for people behind the code? AI isn’t replacing developers. It’s redefining them. Routine tasks are increasingly handled by AI agents, and this frees up developers to become curators, reviewers, architects, and most important problem-solvers.The upshot? Companies may need fewer developers for repetitive work, but the overall demand for skilled engineers remains robust. As AI lowers the barrier to entry, the pool of people who can build software applications expands dramatically. But at the same time, the complexity and ambitions of projects rise, keeping experienced developers in high demand.No doubt, AI coding tools are delivering real productivity gains. Some teams are reporting nearly doubling their code capacity and cutting pull request times in half after adopting AI assistants. Test coverage has increased sharply, resulting in 20 percent fewer production incidents for some organizations. But there is a catch with all this AI-generated code. It’s creating significant new bottlenecks downstream.An example of this is code review, which is becoming a major pain point. Many organizations are experiencing pull request fatigue, with developers rubber-stamping changes just to keep up. Some teams now require three reviewers for AI-generated change, compared to just one before. And in terms of automated testing, systems are getting overwhelmed because every change made with AI sets off a complete round of test.Now we estimate productivity gains from AI in software engineering at about 15–20 percent. But in complex projects, the gains are much lower, as the volume of new code often means more bugs and more rework – and hence more human developers.So where do we go from here? In our view, the future isn’t about fully autonomous software development. Instead, large enterprises are likely to favor an integrated approach, where AI agents and human developers work side by side. AI will automate more of the software development lifecycle. And that not only includes coding – which, coding typically accounts for 10-20 percent of the software development effort – but other areas like testing, security, and deployment. But humans will remain in the loop for oversight, design, and decision-making. And as software gets cheaper and faster to build, organizations won’t just do the same work with fewer people – they likely will do more.In short, the need for skilled developers isn’t going away. But it’s definitely evolving. And in the age of AI, it’s not about man versus machine. It’s about man with machine. And so with more software, we see more developers.Thanks for listening. If you enjoy the show, please leave us a review wherever you listen and share Thoughts on the Market with a friend or colleague today.

24 Loka 20254min

Should AI Spending Worry Investors?

Should AI Spending Worry Investors?

Our Head of Corporate Credit Research Andrew Sheets wades into the debate around whether the boom in artificial intelligence investment is a warning sign for credit markets. Read more insights from Morgan Stanley.----- Transcript ----- Andrew Sheets: Welcome to Thoughts on the Market. I'm Andrew Sheets, Head of Corporate Credit Research at Morgan Stanley.Today – the debate about whether elevated capital expenditure and AI technology is showing classic warning signs of overbuilding and worries for credit.It's Thursday, October 23rd at 2pm in London.Two things are true. AI related investment will be one of the largest investment cycles of this generation. And there is a long history of major investment cycles causing major headaches to the credit market. From the railroads to electrification, to the internet to shale oil, there are a number of instances where heavy investment created credit weakness, even when the underlying technology was highly successful.So, let's dig into this and why we think this AI CapEx cycle actually has much further to run.First, Morgan Stanley has done a lot of good collaborative in-depth work on where the AI related spend is coming from and what's still in the pipeline. And importantly, most of the spending that we expect is still well ahead of us. It's only really ramping up starting now.Next, we think that AI is seen as the most important technology of the next decade by some of the biggest, most profitable companies on the planet. We think this increases their willingness to invest and stick with those investments, even if there's a lot of uncertainty around what the return on all of this expenditure will ultimately be.Third, unlike some other major recent capital expenditure cycles – be they the internet of the late 1990s or shale oil of the mid 2010s, both of which were challenging for credit – much of the spending that we're seeing today on AI is backed by companies with extremely strong balance sheets and significant additional debt capacity. That just wasn't the case with some of those other prior investment cycles and should help this one run for longer.And finally, if we think about really what went wrong with some of these prior capital expenditure cycles, it's often really about overcapacity. A new technology – be it the railroads or electricity or the internet – comes along and it is transformational.And because it's transformational, you build a lot of it. And then sometimes you build too much; you build ahead of the underlying demand. And that can lower returns on that investment and cause losses.We can understand why large levels of AI capital investment and the history of large investment cycles in the past causes understandable concern. But when tying these dynamics together, it's important to remember why large investment cycles have a checkered history. It's usually not about the technology not working per se, but rather a promising technology being built ahead of demand for it and resulting in excess capacity driving down returns in that investment, and the builders lacking the financial resources to bridge that gap.So far, that's not what we see. Data centers are still seeing strong underlying demand and are often backed by companies with exceptionally good resources. We need to watch if either of these change.But for now, we think the AI CapEx cycle has much further to go.Thank you as always for your time. If you find Thoughts on the Market useful, let us know by leaving a review wherever you listen. And also tell a friend or colleague about us today

23 Loka 20253min

The Next Turning Points in Tech

The Next Turning Points in Tech

Our analysts Brian Nowak, Keith Weiss and Matt Bombassei break down the most important tech insights from Morgan Stanley’s Spark Private Company Conference and industry shifts that will likely shape 2026 and beyond. Read more insights from Morgan Stanley.----- Transcript ----- Brian Nowak: Welcome to Thoughts on the Market. I'm Brian Nowak, Morgan Stanley's Head of U.S. Internet Research. I'm joined today by Keith Weiss, Head of U.S. Software Research and Matt Bombassei from my team.Today we're going to talk about private companies and technology – and how they're showing us the direction of travel for disruptive technologies and emerging investment opportunities.It's Wednesday, October 22nd at 10am in New York.Keith and Matt, we just returned from Morgan Stanley's Spark Private Company Conference last week in Los Angeles. It had over 85 private tech companies, 150 plus investor firms. There were a lot of themes that were discussed across the entire tech space impacting a lot of different sectors, including energy, healthcare, financial services, and cybersecurity.Keith, what were some of the biggest takeaways you took away from Spark this year?Keith Weiss: I'd say just to start off with, the Spark Conference is one of my favorite conferences of the year. It's a more intimate conference where you really get to spend time with both the private company executives and founders, as well as investors from the VC community and public company investors. And the conversations are more broad ranging; they're more about the thematics in the industry. They're more long term in nature.So, it's not just a conversation about what's next quarter going to look like, or what data points are you drumming up. You're having these thoughtful conversations about what's going on in the industry and how that's going to impact business models, how it's going to impact innovation cycles, how it's going to impact pricing models, within these companies. So, it tends to be a very interesting conference for me to attend.So, for me, some of the key takeaways. Typically, when we're in these innovation cycles, it feels like everybody's rowing in the same direction. We all understand where the technology's heading, we're all understanding how it's going to be delivered, and it's a race to get there. And you're having a conversation about who's doing best in that race, who's best positioned, who's got a better motor in their race car, if you will.So, to me, one of the big takeaways was we don't have that agreement today, right? There's different players that are looking at this market evolution differently. On one side of the equation, the application vendors – and a lot of this debate is in SaaS based applications. They see SaaS based applications having a very big role in taking these models that are inherently in-determinative and making them to be more determinative and useful within an enterprise context.Bringing them the data that they need to get the job done and the right data; bringing them the context of the business process being solved; bringing the governance that's necessary to use in an enterprise environment. But most importantly, to make it effective and efficient for the large enterprise.On the other side of the equation, you have venture capital investors and more early-stage investors who are looking at this as a huge phase shift, right? This is going to fundamentally change how we build software, how we utilize software, and they worry about a deprecation of that SaaS application layer. They think the model itself is going to start to encompass, it's going to start to subsume a lot more of that application functionality, a lot more of that analytics. And they see a lot more disruption going forward.So that debate within the marketplace, that's something that's interesting to me. It's something that we don't typically see in these innovation cycles. So that's takeaway number one.Takeaway number two, we're still really early days, and that's a little bit implied in in the first statement; I definitely hear a lot of it when I talk to the end customer. When I talk to CIOs. This wasn't necessarily at Spark, but earlier in the week, I was at a CIO conference, there was 150 CIOs in the room. One of the gentlemen on stage asked a question. ‘Who in the room has a good understanding of what we're talking about when we mean Agentic AI, when we mean agentic computing within our enterprise.’ Of the 150 CIOs, four raised their hands. Still very early days in understanding how this is going to evolve, how we're going to actually deliver these capabilities into the enterprise.And the last takeaway I would say is more excitement about the federal government becoming a better customer for software companies overall. People are more interested in new avenues into that federal government. There's been some very successful companies that have opened the door to getting into these federal government contracts without going through the primes, without doing the typical federal government procurement cycles.And that's very interesting to the startup community, which tends to move faster, which tends to drive on innovation versus relationship building; versus being in an existing kind of incumbent prime. So, I thought that opening was – it was pretty interesting as well.Brian Nowak: it sounds like it's still very early, there are a lot of different points of view and no real consensus as to where technologies could go next. However, one theme with an enterprise software – [it] does seem like cybersecurity has a little more of a unified view.So maybe walk us through what you learned from a cybersecurity perspective and what should we be focused on there?Keith Weiss: Yeah, absolutely. If there is a consensus, the consensus is that generative AI and these innovations and the fast pace of innovation is going to be a positive for cybersecurity spending, right? The reason being, there's three main factors that are driving that overall spending.One is expansion of surface area, right? Cybersecurity in one dimension, you can think of how much is there to be protected, right? And if we think about the major themes that we're talking about, we're going to be developing a lot more software, right? The code generation tools are improving software developer productivity. You have an expanding capability of what you can actually automate.We'll be building a lot more software. That software needs to be protected, right? We have new entities that are going to be operating inside of enterprises, and that's the agents. So, CIOs are thinking about this future state where you have tens, thousands, maybe hundreds of thousands of agents operating in the environment, doing work on behalf of end users, but having permissions and having ability to execute business processes. How do we secure that side of the equation? We're talking about outside of just the four walls of the large enterprise, going into more operational technologies, being able to automate more of that work. That needs to be secured as well.So, an expanding surface area is definitely good for the cybersecurity budget. You can almost think of cybersecurity as a tax on that surface area. We generally think about it; somewhere between 4 and 6 percent of IT spend is going to be spent on overall security. So, that's one big driver.The second big driver is the elevated threat environment. So, while we're excited to get our hands on these extended capabilities of generative AI, the bad guys are already there, right? They're taking advantage of this. The sophistication, the volume and the velocity of these attacks is all increasing. That makes a harder job for the existing infrastructure to keep up, and it's going to likely necessitate more spending on cybersecurity to tackle these newer challenges; the newer dynamism within the cybersecurity threat appropriately. So, you're going to have to use generative AI to counter the generative AI.And then the last component of it; the last driver would be the regulatory environment. Regulatory tends to have some cybersecurity angles. If we think about it here, we're seeing it in terms of data governance is probably the big one. Where does this data go when it goes into the model? Are we putting the right controls around it? Do we have the right governance on it? So that's a big area of concern.A lot of complaining going on at the conference about the lack of consistency in that regulatory environment. All these different initiatives coming up from the state – really creates a challenging environment to navigate. But that's all good-ness for cybersecurity vendors that can help you get into compliance with these new regulations that are coming up. So overall, a lot of positivity around cybersecurity spending and startups definitely look to take advantage of that.Brian Nowak: Matt, so Keith says there's lack of consensus and boats being rode in every direction on what should be adopted first. And only 3 percent of CIOs know what agentic AI means. What did you learn about early signal on adoption? And some of the barriers to adoption? And hurdles that companies are talking about that they need to overcome to really adopt some of these new tools?Matt Bombassei: Yeah. Well, to Keith's point, it is really early, right? And that was a consistent theme that we heard from our companies at the conference. They are seeing early signs of cost efficiency, making employees more productive as opposed to maybe broad scale layoffs. But it's the deployment of these model technologies into specific sub-verticals – so accounting, legal engineering – where that adoption is driving greater efficiency within the organization.These companies are also adopting models that are smaller and a bit more fine tuned to their specific work product. And so that comes at a lower cost. We heard companies talking about costs at 1/50 of the cost of the broader foundational models when they're deploying it within the organization. And so, cost efficiency is something that we're seeing.At the same time, to speak to how early it is, one of the biggest hurdles here is change management and actually adoption. Getting people to use these products, getting them to learn the new technologies, that is a big hurdle. You know, you can lead a horse to water, you can't make it drink, right? And so, getting people to actually deploy these technologies is something that organizations are thinking through. How do we approach [it]?Brian Nowak: And you make an autonomous car drive? I know you've been doing a lot of work on autonomous driving more broadly. There were some autonomous driving and autonomous driving technology companies at Spark. What were your takeaways on autonomous driving from last week?Matt Bombassei: Yeah, well, not only can you make an autonomous car drive, you can make a truck drive and a bunch of other physical equipment. I think that was one of the takeaways here was that these neural nets that are powering autonomous vehicles are actually becoming much more generalizable. The integration of the transformer architecture into these neural nets is allowing them to take the context from one sub-vertical and deploy it in another vertical.So, we heard that 80 to 90 percent of the software, the underlying neural net, is applicable across these verticals. So, think applicable from autonomous ride sharing to autonomous trucking, right? What that means from our point of view is that it's important to get the scale of total miles driven – to establish that kind of safety hurdle if you're these companies.But also, don't necessarily think of these companies as defined by the vertical that they're operating in. If these models truly are generalizable, a company that's successful and scaled and autonomous ride hailing can switch or navigate verticals to also become successful potentially in trucking and other industries as well. So, the generalization of these models is particularly interesting for scale, and long-term market position for these companies.Brian Nowak: It's fascinating. Well, from consumer and enterprise adoption, the future of agentic computing and autonomous driving, there will be a lot more themes we all have to stay on top of. Keith, Matt, thanks so much for taking the time today.Keith Weiss: Great speaking with you Brian.Matt Bombassei: Thanks for having us.Brian Nowak: And thanks for listening. If you enjoy Thoughts on the Market, please leave us a review wherever you listen and share the podcast with a friend or colleague today.

22 Loka 202511min

How to Navigate U.S.-China Tensions

How to Navigate U.S.-China Tensions

Our Global Head of Fixed Income Research and Public Policy Michael Zezas discuss the latest developments in U.S.-China relations and how they could affect investors.Read more insights from Morgan Stanley.----- Transcript ----- Welcome to Thoughts on the Market. I’m Michael Zezas, Global Head of Fixed Income Research and Public Policy Strategy. Today, we’re talking about the U.S. and China—why the relationship remains complicated, and what it means for markets. It’s Tuesday, Oct 21st, at 12:30pm in New York. If you’ve been following headlines, you know that U.S.-China relations are rarely out of the news. But beneath the surface, the dynamics are more nuanced than the daily soundbytes suggest. Investors often ask: Are we headed for a decoupling of the two economies, or is there room for cooperation? The answer, as always, is—it’s complicated. Let’s start with the basics. The U.S. and China are deeply intertwined economically, but strategic competition has intensified. Recent years have seen tariffs, export controls, and restrictions on technology transfer. Yet, there’s still plenty of trade between the two countries, and both economies are dependent on each other for growth and innovation. So what’s going on now? In recent weeks, China has moved to tighten rare earth export controls and the U.S. has proposed 100 percent tariffs in return. If this came to pass, these events could mark a clear economic split. But given the interdependencies we just cited, neither Washington nor Beijing seems eager for a true split, at least not anytime soon. The economic costs would be staggering, and both sides know it. So, a truce seems more likely, perhaps with somewhat different terms than the narrow semis-for-rare earths agreement they made this spring. And longer term, this episode seems to be a part of a broader dynamic, where rolling negotiations and truces are more likely than either a durable trade peace or a hard economic decoupling. For fixed income investors, this drives some important considerations. First, U.S. industrial policy is ramping up, with clear implications for AI infrastructure. AI is an area where the U.S. views it as essential that they outcompete China. Supported by renewed CapEx incentives from the latest tax bill, it’s clear to us that U.S. companies will be pushing further into AI development, where my colleagues have identified $2.9 trillion of data center financing needs over the next three years, about half of which will come from various credit markets. And for credit investors, this presents an important opportunity. Another consideration is how markets will balance near-term growth risks with an array of medium term growth possibilities. As our U.S. economics team has pointed out, the evidence suggests that corporates haven’t yet been forced to make tough decisions about passing on or absorbing tariff costs, underscoring that trade-related growth pressures aren’t yet in the rearview. The ongoing U.S. government shutdown doesn’t help either. It’s all a good argument for why bond yields could move lower in the near term. But also, we should expect yield curves could steepen more, with higher relative yields in longer maturities. This would reflect greater uncertainties around higher fiscal deficits, inflation, and economic growth. Our economists have been calling out the mixed messages in economic data, as well as a U.S. fiscal sustainability picture that appears reliant on acceleration in corporate CapEx for a manufacturing and AI-driven growth burst. In sum, the U.S.-China relationship is evolving, with global implications that don’t lend themselves to easy narratives or quick fixes. Our challenge will continue to be crafting investment strategies that reflect durable policy undercurrents, the signal amid news headline noise. Thanks for listening. If you enjoy the show, please leave us a review wherever you listen and share Thoughts on the Market with a friend or colleague.

21 Loka 20253min

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