Inside GRAPPA7 Marras 2025

Sleep and PsA: Exploring the Hidden Connection

In this episode of Inside GRAPPA, host Dr. Mio Nakamura (University of Michigan) speaks with Dr. Tina Bhutani-Jacques, MD, MAS, FAAD (Synergy Dermatology / University of California San Francisco) about her groundbreaking study on the role of sleep in psoriasis disease severity. Funded by the GRAPPA Pilot Research Grant, Dr. Bhutani-Jacques’s work is the first prospective cohort study to objectively examine sleep patterns in psoriasis patients.

💡 Together, they explore:

How a patient’s unexpected experience sparked the idea to investigate sleep and psoriasis
The design and findings of the pilot study using three nights of polysomnography in patients and healthy controls
Early results showing reduced sleep efficiency, more awakenings, and nearly an hour less sleep per night among psoriasis patients
The potential link between poor sleep, inflammation, and cardiovascular comorbidities
Practical advice for clinicians on discussing sleep with psoriasis patients
Next steps, including home-based sleep studies using wearables for more naturalistic data

🎧 Tune in for an engaging discussion that highlights how sleep—often overlooked—may be a key factor in understanding psoriatic disease and improving patient outcomes.

🔗 Learn more about GRAPPA’s research initiatives at grappanetwork.org.

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