What Keeps Facebook Up at Night

Last May, a 12-year-old with sickle cell anemia was the first person to receive a new gene therapy to treat the disease. The process is painful, expensive, and still frightening and uncertain, but biomedical researchers are cautiously calling it a “cure.”Guests:Gina Kolata, medical reporter for the New York TimesDeb and Keith Cromer, parents to Kendric Cromer, the first person in the world to go through a commercially approved gene therapy for sickle cell anemia.Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen.Podcast production by Evan Campbell, Patrick Fort, and Cheyna Roth. Hosted on Acast. See acast.com/privacy for more information.

24 Marras 202428min

The Department of Justice has released its recommendations for how Google’s monopoly on web search should be broken up. Top of their wishlist? Spinning off their web browser Chrome. But with a new administration coming to the White House, will Google have to comply?Guest: Leah Nylen, antitrust reporter for Bloomberg NewsWant more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen.Disclosure in Podcast Description: A Bond Account is a self-directed brokerage account with Public Investing, member FINRA/SIPC. Deposits into this account are used to purchase 10 investment-grade and high-yield bonds. As of 9/26/24, the average, annualized yield to worst (YTW) across the Bond Account is greater than 6%. A bond’s yield is a function of its market price, which can fluctuate; therefore, a bond’s YTW is not “locked in” until the bond is purchased, and your yield at time of purchase may be different from the yield shown here. The “locked in” YTW is not guaranteed; you may receive less than the YTW of the bonds in the Bond Account if you sell any of the bonds before maturity or if the issuer defaults on the bond. Public Investing charges a markup on each bond trade. See our Fee Schedule. Bond Accounts are not recommendations of individual bonds or default allocations. The bonds in the Bond Account have not been selected based on your needs or risk profile. See https://public.com/disclosures/bond-account to learn more. Hosted on Acast. See acast.com/privacy for more information.

22 Marras 202420min

The Department of Justice has released its recommendations for how Google’s monopoly on web search should be broken up. Top of their wishlist? Spinning off their web browser Chrome. But with a new administration coming to the White House, will Google have to comply?Guest: Leah Nylen, antitrust reporter for Bloomberg NewsWant more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen.Disclosure in Podcast Description: A Bond Account is a self-directed brokerage account with Public Investing, member FINRA/SIPC. Deposits into this account are used to purchase 10 investment-grade and high-yield bonds. As of 9/26/24, the average, annualized yield to worst (YTW) across the Bond Account is greater than 6%. A bond’s yield is a function of its market price, which can fluctuate; therefore, a bond’s YTW is not “locked in” until the bond is purchased, and your yield at time of purchase may be different from the yield shown here. The “locked in” YTW is not guaranteed; you may receive less than the YTW of the bonds in the Bond Account if you sell any of the bonds before maturity or if the issuer defaults on the bond. Public Investing charges a markup on each bond trade. See our Fee Schedule. Bond Accounts are not recommendations of individual bonds or default allocations. The bonds in the Bond Account have not been selected based on your needs or risk profile. See https://public.com/disclosures/bond-account to learn more. Hosted on Acast. See acast.com/privacy for more information.

22 Marras 202420min

On the campaign trail, Donald Trump promised to deport millions of “illegal immigrants.” As he prepares to return to the White House, it’s time to figure out how that would work—and who it would include.Guest: Molly O'Toole, reporter covering immigration and security.Want more What Next? Join Slate Plus to unlock full, ad-free access to What Next and all your other favorite Slate podcasts. You can subscribe directly from the What Next show page on Apple Podcasts and Spotify. Or, visit slate.com/whatnextplus to get access wherever you listen.Podcast production by Elena Schwartz, Paige Osburn, Anna Phillips, Madeline Ducharme and Rob Gunther. Hosted on Acast. See acast.com/privacy for more information.

21 Marras 202423min

Donald Trump’s picks for cabinet positions are causing a lot of rolling of eyes and gnashing of teeth. But even though they don’t have official titles or well-known names, the future of Trump’s agenda might lie with a group of White House-appointed “czars,” who are also being announced with less fanfare. Guest: David Dayen, executive editor of The American Prospect.Want more What Next? Join Slate Plus to unlock full, ad-free access to What Next and all your other favorite Slate podcasts. You can subscribe directly from the What Next show page on Apple Podcasts and Spotify. Or, visit slate.com/whatnextplus to get access wherever you listen.Podcast production by Elena Schwartz, Paige Osburn, Anna Phillips, Madeline Ducharme and Rob Gunther. Hosted on Acast. See acast.com/privacy for more information.

20 Marras 202425min

Donald Trump retook the presidency, in part, by doing much better in American cities in 2024 than ever before. Why did these urban Democratic strongholds shift towards Republicans, and are these changes permanent? Guests:Henry Grabar, staff writer at Slate.Ron Kim, representative for New York State’s 40th Assembly District.Want more What Next? Join Slate Plus to unlock full, ad-free access to What Next and all your other favorite Slate podcasts. You can subscribe directly from the What Next show page on Apple Podcasts and Spotify. Or, visit slate.com/whatnextplus to get access wherever you listen.We want to hear from you! Submit your answers to our What Next listener survey at slate.com/WhatNextSurvey.Podcast production by Elena Schwartz, Paige Osburn, Anna Phillips, Madeline Ducharme and Rob Gunther. Hosted on Acast. See acast.com/privacy for more information.

19 Marras 202424min

Rep. Jamie Raskin led the second impeachment of Donald Trump, the effort to get him off the ballot under the 14th amendment, and campaigned to beat him at the ballot box. With Trump heading back to the White House with even fewer guardrails, Raskin’s still not giving up the fight.Guest: Jamin “Jamie” Raskin is the U.S. representative for Maryland’s 8th congressional districtWant more What Next? Join Slate Plus to unlock full, ad-free access to What Next and all your other favorite Slate podcasts. You can subscribe directly from the What Next show page on Apple Podcasts and Spotify. Or, visit slate.com/whatnextplus to get access wherever you listen.Podcast production by Elena Schwartz, Paige Osburn, Anna Phillips, Madeline Ducharme and Rob Gunther. Hosted on Acast. See acast.com/privacy for more information.

18 Marras 202421min

Since Elon Musk took over, Twitter—er, sorry “X”—has been slowly deflating. But given that soon you’ll be getting yelled at by right-wing trolls directly from White House press briefings, and your data is being swept up to train A.I., is there any reason to stay on the site at all anymore? Guest: Nitish Pahwa, Slate business writer.Want more What Next TBD? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen. Hosted on Acast. See acast.com/privacy for more information.

17 Marras 202422min