Examining Volume of Distribution (Ep. 56)
In this episode we’re going to define Volume of Distribution, look at the different types of Volume of Distribution parameters, talk about how we actually calculate it, examine what drives its value, ...
20 Huhti 19min
Talking about data science with Mike Stackhouse (Ep. 55)
This episode is an interview with Michael Stackhouse, the Chief Innovation Officer at Atorus Research. We discussed a variety of topics such as modern data science tools, why regulatory agencies want ...
16 Maalis 45min
Using Accelerator Mass Spectrometry in Clinical Pharmacology
This episode is an interview with Dr. Wouter Vaes, the Chief Science Officer of Peregrion. We discuss how accelerator mass spectrometry is being used in early clinical development for drug metabolism ...
16 Helmi 38min
When to use model-informed drug development (Ep. 52)
This episode is a collection of my thoughts on model-informed drug development and where different modeling modalities fit into the development schedule. These are just my opinions and each developmen...
22 Joulu 202528min
QSP Modeling with Ahmed Elmokadem (Ep. 51)
In this episode I chat with Ahmed Elmokadem about QSP modeling. Ahmed, from Metrum Research Group, is an expert consultant in QSP modeling and how it can be used to provide a framework to connect mech...
24 Marras 202544min
CDISC datasets and ACoP 2025 (Ep. 50)
In this episode I discuss dataset-JSON, a new proposed data standard for CDISC files and explain some of the CDISC files I use in my clinical pharmacology work. I end with some brief thoughts about th...
27 Loka 202518min
Statistics in Pharmacokinetics (Ep. 49)
In this episode I discuss review statistics that are commonly used in pharmacokinetics and pharmacometrics work. I reviewed the basic theory of the normal distribution and then discussed various indiv...
22 Syys 202525min
