What Actually Happens to Your Brain When You Start Fasting | Dr Mindy Pelz

It's a controversial topic, fasting, especially for women. Dr. Mindy Pelz was teaching women to fast primarily because they wanted to lose weight, but what she was witnessing was women saying things like, "I lost weight, but my hair's falling out. I don't have a period anymore. I sat down with Dr. Mindy Pelz, New York Times bestselling author of Age Like a Girl, hormone expert, and the voice redefining fasting for women - because doing it wrong can wreck your health. We explore why fasting affects women differently, how ketones can restore brain function during menopause, and why understanding your hormonal cycle is critical for metabolic health, cognitive performance, and longevity. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro 01:50 What put Dr. Mindy Pelz on the map 03:14 The truth about fasting vs intermittent fasting 05:13 How the brain uses glucose vs ketones 07:25 Why the brain "eats itself" during menopause 10:14 What is mitophagy and cellular autophagy 13:11 Why autophagy is the body's repair system 15:24 The 12-hour vs 17-hour vs 72-hour fast 17:23 Why women's cycles are disrupted by fasting 19:59 The fasting cycle for women 21:05 Lactate as a fuel source for the brain 23:01 Hemoglobin A1C and insulin resistance 27:36 Understanding CGM data correctly 30:13 Where women should start at 48 32:01 HRT: personal decision or necessity? 34:15 The nervous system shift during perimenopause 38:48 The grandmother hypothesis and evolutionary sensitivity 41:09 The "menopause divorce" phenomenon 44:18 Dementia, Alzheimer's, and women46:17 Dopamine, novelty, and neuroplasticity47:23 Cold water immersion and trauma rewiring51:19 Cold water and cortisol for women53:51 Exercise, BDNF, and brain health55:21 Serotonin, light exposure, and sleep58:00 Glycine, bone broth, and longevity01:02:26 Preparing for perimenopause and menopause 01:04:24 Acetylcholine, storytelling, and memory 01:08:38 Why eggs and cholesterol matter for the brain _______ A huge thank you to my sponsors for supporting this episode. Check them out and enjoy exclusive discounts: Ketone-IQ: Mental clarity that lasts - without the crash. Visit https://ketone.com/NEURO for 30% OFF your subscription order - PLUS receive a free gift with your second shipment or find Ketone-IQ at Target stores nationwide and get your first shot free! IQBAR: The New Year gives us all a chance to reset. Maximize your brain and body's potential with IQBAR's protein bars, hydration mixes, and mushroom coffees. Text NEURO to 64000 to get 20% off all IQBAR products, plus FREE shipping. Caraway: Visit Carawayhome.com/neuro10 or use code neuro10 at checkout to take an additional 10% off your next purchase. Caraway. Non-Toxic cookware made modern. Cure Hydration: For The Neuro Experience listeners, you can get 20% off your first order at curehydration.com/NEURO with code NEURO. Cure is FSA/HSA approved, so you can use your FSA or HSA funds to stay hydrated the smart way. Jones Road Beauty: Use code NEURO at jonesroadbeauty.com to get a Free Cool Gloss with your first purchase! _______ I’m Louisa Nicola - clinical neurophysiologist - Alzheimer’s prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer’s risk - and staying mentally sharp for life, you’re in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices