Symposium | Implications for clinical practice: Managing AML with FLT3-ITD and -TKD mutations
AML Hub11 Helmi

Symposium | Implications for clinical practice: Managing AML with FLT3-ITD and -TKD mutations

The AML Hub held a virtual symposium on November 19, 2025, titled Understanding the differences between FLT3-ITD and -TKD mutations in AML: Implications for clinical practice. Here, we share a presentation from the symposium by Gail J. Roboz, Weill Cornell Medicine, New York, US, in which she discussed the management of patients with acute myeloid leukemia (AML) with FLT3-internal tandem duplication (ITD) and FLT3-tyrosine kinase domain (TKD) mutations in clinical practice.


Roboz reflected on whether 7+3 regimens are the most appropriate approach for older patients with FLT3-mutated AML, and reviewed considerations for using targeted FLT3 inhibitor therapies in combination with standard intensive chemotherapy. She then highlighted the importance of measurable residual disease (MRD) assessment in guiding treatment decisions before and after allogeneic hematopoietic stem cell transplantation (allo-HSCT), and the potential of triplet therapies for the treatment of patients with FLT3m AML.


This educational resource is independently supported by Daiichi Sankyo. All content was developed by SES in collaboration with an expert steering committee. Funders were allowed no influence on the content of this resource.

Hosted on Acast. See acast.com/privacy for more information.

Jaksot(35)

Addressing uncertainty in patient selection for transplant in AML

Addressing uncertainty in patient selection for transplant in AML

During a meeting of the AML Hub Steering Committee, held on July 22, 2025, Charles Craddock chaired a discussion on the topic: Addressing uncertainty in patient selection for transplant. The discussio...

22 Syys 202523min

Integrating menin inhibitors into the treatment landscape of AML: Future directions

Integrating menin inhibitors into the treatment landscape of AML: Future directions

The AML Hub was pleased to speak with Joshua Zeidner, Associate Professor of Medicine at the University of North Carolina Lineberger Comprehensive Cancer Center in Durham, North Carolina. We asked for...

3 Syys 20255min

Know AML webinar | Closing remarks and Q&A

Know AML webinar | Closing remarks and Q&A

Know AML conducted a healthcare professional (HCP) and patient webinar on April 23, 2025, titled ‘Mutation testing in AML: What you need to know’. Here, we share closing remarks and questions from the...

26 Kesä 20259min

Know AML webinar | How can physicians and patients communicate more clearly about mutation testing in AML going forward?

Know AML webinar | How can physicians and patients communicate more clearly about mutation testing in AML going forward?

This independent educational activity is supported by Thermo Fisher Scientific. All content is developed independently by the faculty. The funder is allowed no influence on the content. Know AML hoste...

19 Kesä 20259min

Know AML webinar | Empowering patients to ask their physician the right questions during their AML journey

Know AML webinar | Empowering patients to ask their physician the right questions during their AML journey

Know AML hosted a webinar for patients and healthcare professionals (HCPs) on April 23, 2025, titled ‘Mutation testing in AML: What you need to know’. Here, we share a discussion between Gail J. Roboz...

13 Kesä 202527min

Know AML webinar | What are mutations, and why do they matter in AML?

Know AML webinar | What are mutations, and why do they matter in AML?

Know AML hosted a webinar for patients and healthcare professionals (HCPs) on April 23, 2025, titled ‘Mutation testing in AML: What you need to know’. Here, we share a presentation by the chair, Charl...

9 Kesä 202513min

“How I treat” a patient with DNMT3A-mutated AML in remission post intensive chemotherapy

“How I treat” a patient with DNMT3A-mutated AML in remission post intensive chemotherapy

The AML Hub was pleased to speak with Cristina Papayannidis, Universitaria di Bologna, Bologna, IT. We asked, How do you treat a patient with DNMT3A-mutated acute myeloid leukemia (AML) in remission p...

3 Loka 20245min

CPX-351 as first-line treatment in AML: Real-world data

CPX-351 as first-line treatment in AML: Real-world data

Here, we summarize five real-world studies presented at EHA 2024 on real-world outcomes of patients with AML who received CPX-351 as a first-line treatment. Hosted on Acast. See acast.com/privacy fo...

30 Syys 202416min

Suosittua kategoriassa Koulutus

rss-murhan-anatomia
psykopodiaa-podcast
voi-hyvin-meditaatiot-2
rss-narsisti
adhd-podi
rss-duodecim-lehti
jari-sarasvuo-podcast
leveli
rss-liian-kuuma-peruna
rss-valo-minussa-2
rss-koira-haudattuna
rahapuhetta
rss-niinku-asia-on
salainen-paivakirja
psykologia
ihminen-tavattavissa-tommy-hellsten-instituutti
rss-uskonto-on-tylsaa
rss-luonnollinen-synnytys-podcast
rss-tietoinen-yhteys-podcast-2
rss-arkea-ja-aurinkoa-podcast-espanjasta